检索结果-内蒙古大学图书馆

Noninvasive electrochemical biosensor for rapid detection of Helicobacter pylori in patient saliva

sensors and Actuators B: Chemical 2025年 442卷

作者： Stella Schuster da Silva Tatiana Lima Valério Bruna M. Hryniewicz Hussamaldeen Jaradat Mel De Souza Wendhausen Araújo Carla Adriane Royer Beatriz Borba Ortiz Andrei Elias Deller Leandro Yoshimi Kashiwagui Paulo de Souza Fonseca Guimarães Jaqueline de Carvalho Oliveira Daniela Fiori Gradia Olfa Kanoun Carolina Camargo de Oliveira Marcio Vidotti Laboratory of Inflammatory and Neoplastic Cells Cell Biology Department Section of Biological Sciences – Federal University of Paraná (UFPR) Curitiba PR 81531-980 Brazil Grupo de Pesquisa em Macromoléculas e Interfaces Federal University of Paraná (UFPR) Curitiba PR 81531-980 Brazil Institute of Chemistry University of Campinas - UNICAMP Campinas 13083-970 Brazil Professorship of Measurement and Sensor Technology Faculty of Electrical Engineering and Information Technology Chemnitz University of Technology Chemnitz 09126 Germany Laboratory of Human Cytogenetics and Oncogenetics Postgraduate Program in Genetics Department of Genetics Federal University of Paraná Curitiba 81531-980 Brazil Cajuru University Hospital Pontifícia Universidade Católica do Paraná Curitiba PR 80050-350 Brazil

The carcinogenic bacterium Helicobacter pylori infect over half the global population, with a higher prevalence in low-income countries. It is linked to diseases such as chronic gastritis, peptic ulcers, and gastric cancer, a leading cause of cancer-related deaths worldwide. The gold standard diagnostic method involves histopathological evaluation of gastric biopsy tissue via upper gastrointestinal endoscopy—an invasive, complex, and time-intensive procedure requiring specialized professionals. This study presents a noninvasive alternative: an impedimetric electrochemical biosensor for H. pylori antigen detection in saliva. The biosensor was developed using a screen-printed carbon electrode modified with polypyrrole nanotubes and carboxylated multi-walled carbon nanotubes. Monoclonal antibodies targeting CagA, a cytotoxic effector protein of H. pylori , were immobilized on carbon nanotubes using EDC/NHS chemistry. The platform was characterized via scanning electron microscopy and electrochemical techniques. Electrochemical impedance spectroscopy (EIS) was employed for analyte detection, with an analytical curve constructed in phosphate-buffered saline (PBS) spiked with CagA protein. The biosensor demonstrated a linear detection range of 0.5 pg mL⁻¹ to 3.3 ng mL⁻¹ and a detection limit of 109.9 fg mL⁻¹ . Validation with patient saliva samples, confirmed by histopathology and rapid urease testing, yielded 97 % accuracy, 80 % sensitivity, and 100 % specificity. Results were obtained within 15 min. This EIS-based biosensor offers a sensitive, innovative, and noninvasive platform for early H. pylori diagnosis, which is essential for preventing severe diseases such as gastric cancer.

关键词： Helicobacter pylori Electrochemical biosensor Polypyrrole Nanotechnology Biomedical engineering

来源：评论

学校读者我要写书评

暂无评论

Ultra precise motion error measurement of rotation kinematics for the integration in nanomeasuring and nanofabrication machines 33

Ultra precise motion error measurement of rotation kinematic...

引用

33rd Annual Meeting of the American Society for Precision engineering, ASPE 2018

作者： Fern, Florian Füßl, Roland Schienbein, Ralf Theska, René Institute of Process Measurement and Sensor Technology Technische Universität Ilmenau Ilmenau Germany Department of Precision Engineering Technische Universität Ilmenau Ilmenau Germany

来源：评论

学校读者我要写书评

暂无评论

Physical layer security in multimode fiber optical networks

arXiv

引用

arXiv 2019年

作者： Rothe, Stefan Koukourakis, Nektarios Radner, Hannes Lonnstrom, Andrew Jorswieck, Eduard Czarske, Jürgen W. Technische Universität Dresden Faculty of Electrical and Computer Engineering Laboratory of Measurement and Sensor System Technique Dresden01062 Germany Technische Universität Braunschweig Faculty of Electrical Engineering Information Technology Physics Institute for Communications Technology Braunschweig38106 Germany

Inverse precoding algorithms in multimode fiber based communication networks are used to exploit mode dependent losses on the physical layer. This provides an asymmetry between legitimate (Bob) and unlegitimate (Eve) receiver of messages resulting in a significant SNR advantage for Bob. In combination with dynamic mode channel changes, Eve has no chance to reconstruct a sent message even in a worst case scenario in which she is almighty. This is the first time, Physical Layer Security in a fiber optical network is investigated on the basis of measured transmission matrices. These results show that messages can be sent securely with conventional communication techniques. Translating the task of securing data from software to hardware represents the potential of a scientific paradigm shift. The introduced technique is a step towards the development of cyber physical systems. Copyright © 2019, The Authors. All rights reserved.

关键词： Multimode fibers

来源：评论

学校读者我要写书评

暂无评论

The Emerging Field of Quantum Based measurements for Pressure, Vacuum and beyond 22

The Emerging Field of Quantum Based Measurements for Pressur...

引用

22nd World Congress of the International measurement Confederation, IMEKO 2018

作者： Hendricks, J. Ahmed, Z. Barker, D. Egan, P. Douglass, K. Eckel, S. Fedchak, J. Klimov, N. Ricker, J. Scherschligt, J. Stone, J. National Institute of Standards and Technology Physical Measurement Laboratory Sensor Science Division Thermodynamic Metrology Group 100 Bureau Drive GaithersburgMD20899-8363 United States National Institute of Standards and Technology Physical Measurement Laboratory Engineering Physics Division Dimensional Metrology Group 100 Bureau Drive GaithersburgMD20899-8363 United States

The future of pressure, vacuum and even temperature measurement will employ lasers, Fabry-Perot optical cavities, cold atom traps and lots of quantum physics. For pressure measurement of a gas, photons interact at the quantum level such that light travels at a slower speed in gas than it does in vacuum. For extreme vacuum measurements, cold atom traps will be used to detect single collisions between gas trapped cold atoms enabling the number density of the gas to be measured. For temperature measurement is performed using silicon photonics to detect the small changes in refractive index in micro machined siliconphontoic cavities coupled to optical fibers. For dynamic pressure, NIST is developing a method where the unique quantum mechanical characteristics of the molecules are themselves the standard for pressure, making it consistent with the quantum-SI. Our approach is to use independent molecular spectroscopy as a dynamic measurement of pressure, where the pressure and temperature is ascertained by measuring time-resolved pressure-broadened spectra of CO molecules. This paper briefly reviews the status of these projects currently underway at the NIST Thermodynamic Metrology Group. © Published under licence by IOP Publishing Ltd.

关键词： Temperature measurement

来源：评论

学校读者我要写书评

暂无评论

Retrospective motion correction for Fast Spin Echo based on conditional GAN with entropy loss

引用

Journal of Physics: Conference Series 2021年第1期1848卷

作者： Yalei Chen Pingan Li Kewen Liu Qingjia Bao Zhao Li Xiaojun Li Information and Communication Engineering Wuhan University of Technology Wuhan Hubei 430070 China Hubei Key Laboratory of Broadband Wireless Communication and Sensor Networks Wuhan University of Technology 430070 Wuhan China Department of Chemical and Biological Physics Weizmann Institute of Science Rehovot Israel State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Wuhan Center for Magnetic Resonance Wuhan Institute of Physics and Mathematics Innovation Academy for Precision Measurement Science and Technology 430071Wuhan China

We proposed a new end-to-end motion correction method based on conditional generative adversarial network (GAN) and minimum entropy of MRI images for Fast Spin Echo (FSE) sequence. The network contains an encoder-decoder generator to generate the motion-corrected images and a PatchGAN discriminator to classify an image as either real (motion-free) or fake(motion-corrected). Moreover, the image's entropy is set as one loss item in the cGAN's loss as the entropy increases monotonically with the motion amplitude, indicating that entropy is a good criterion for motion. The results show that the proposed method can effectively reduce the artifacts and obtain high-quality motion-corrected images from the motion-affected images in both pre-clinical and clinical datasets.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Correction to: Quantitative measurement of density fluctuations with a full‑field laser interferometric vibrometer

引用

Experiments in Fluids 2020年第4期61卷 1-1页

作者： Greiffenhagen, Felix Woisetschläger, Jakob Gürtler, Johannes Czarske, Jürgen Institute for Thermal Turbomachinery and Machine Dynamics Graz University of Technology Graz Austria Laboratory of Measurement and Sensor System Technique Faculty of Electrical and Computer Engineering Technische Universität Dresden Dresden Germany

The original published article contains error in equation and reference.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Acoustic Energy Harvesting with Irradiated Cross-linked Polypropylene Piezoelectret Films

Acoustic Energy Harvesting with Irradiated Cross-linked Poly...

引用

第二届振动与能量收集应用国际学术会议

作者： Yuan Xue Jinfeng Zhao Xiaoqing Zhang Gerhard M.Sessler Mario Kupnik Shanghai Key Laboratory of Special Artificial Microstructure Materials and Technology School of Phys School of Aerospace Engineering and Applied Mechanics Tongji University100 Zhangwu Road200092 Shan Institute for Telecommunications Technology Technische Universit?t DarmstadtMerckstrasse 2564283 D Measurement and Sensor Technology Group Technische Universit?t DarmstadtMerckstrasse 2564283 Darms

来源：评论

学校读者我要写书评

暂无评论

Contribution to the mechanical enhancement of load cells in precision weighing technology by means of advanced adjustment strategies 17

Contribution to the mechanical enhancement of load cells in ...

引用

17th International Conference of the European Society for Precision engineering and Nanotechnology, EUSPEN 2017

作者： Darnieder, Maximilian Marangoni, Rafael R. Theska, René Fröhlich, Thomas Rahneberg, Ilko Institute of Design and Precision Engineering Precision Engineering Group Department of Mechanical Engineering Technische Universität Ilmenau Germany Institute of Process Measurement and Sensor Technology Process Measurement Group Department of Mechanical Engineering Technische Universität Ilmenau Germany

ISBN: (纸本)9780995775107

The accuracy of force measurement systems is predominantly influenced by its stiffness towards deflection. Monolithic mechanical systems in precision weighing technology rely on ultrathin flexure hinges. Further stiffness reduction by a decrease of the minimum hinge thickness is unfavourable. Consequently, the present concept relies on compensation rather than a reduction of the stiffness. Based on precise adjustments, the system's state is altered towards an astatic state. Hereby, the overall stiffness and the tilt sensitivity is reduced. These properties have been determined as major contributions to the measurement error. The results of the theoretical investigations form a basis for future experiments and a further improvement of load cells.

关键词： Stiffness

来源：评论

学校读者我要写书评

暂无评论

Multi-component force measurement in micromachining

Multi-component force measurement in micromachining

引用

作者： Marangoni, Rafael R. Schleichert, Jan Rahneberg, Ilko Mastylo, Rostyslav Manske, Eberhard Fröhlich, Thomas Technische Universität Ilmenau Faculty of Mechanical Engineering Institute of Process Measurement and Sensor Technology PF 100 565 Ilmenau98684 Germany

An experimental setup for performing micro-scratching tasks and measuring the forces involved in the process is presented in this paper. The main component of the system is a multi-component force and torque sensor based on the principle of electromagnetic force compensation (EMFC). With this device it is possible to perform the micromachining process itself while simultaneously measuring the interaction forces between the tool tip and the test specimen. Experiments were performed with specimens of polished steel, silicon and glass. Planar micro-structures could be produced and tool point interaction forces in the order of some millinewtons were measured during the process. © 2017 Walter de Gruyter Berlin/Boston.

关键词： Micromachining

来源：评论

学校读者我要写书评

暂无评论

Combined development and test of product-service systems in early product development stages for customized, availability-oriented business models in the capital goods industry

引用

Procedia CIRP 2018年 72卷 714-719页

作者： Felix Ströer Paaranan Sivasothy Karl-G. Faißt Hristo Apostolov Thomas Eickhoff Dani Bechev Georgis Bulun Jörg Seewig Martin Eigner Bernd Sauer Institute for Measurement and Sensor-Technology Gottlieb-Daimler-Str. 44 67663 Kaiserslautern Germany Institute for Virtual Product Engineering Gottlieb-Daimler-Str. 44 67663 Kaiserslautern Germany Institute of Machine Elements Gears & Transmissions Gottlieb-Daimler-Str. 44 67663 Kaiserslautern Germany

Availability-Oriented Product-Service Systems (AOPSS) give manufacturers of capital goods the opportunity to expand their offerings while fulfilling the customers’ needs for product availability. In turn, they generate special requirements for the early product development phase. Condition monitoring has to be taken into account, which results in a contradiction since learning-based condition monitoring approaches require large amounts of data which isn’t available in that particular stage. Techniques from model-based systems engineering allow solving problems newly arising when developing parts or products in AOPSS. The approach proposed in the paper is being illustrated based on a use case from the agricultural industry.

关键词： Product-Service Systems Model-Based Systems engineering Digital Twin Conditon Monitoring Physical Modeling

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：