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Was Wuhan the early epicenter of the COVID-19 pandemic?——a critique

National science Review 2023年第4期10卷 19-21页

作者： Yanan Cao Lingling Chen Hua Chen Yupeng Cun Xiaofeng Dai Hongli Du Feng Gao Fengbiao Guo Yalong Guo Pei Hao Shunmin He Shunping He XiongLei He Zheng Hu Boon-Peng Hoh Xin Jin Qian Jiang Qinghua Jiang Asifullah Khan Hong-Zhi Kong Jinchen Li Shuai Cheng Li Ying Li Qiang Lin Jianquan Liu Qi Liu Jian Lu Xuemei Lu Shujin Luo Qinghua Nie Zilong Qiu Tieliu Shi Xiaofeng Song Jianzhong Su Sheng-ce Tao Chaolong Wang Chuan-Chao Wang Guo-Dong Wang Jiguang Wang Qi Wu Shaoyuan Wu Shuhua Xu Yu Xue Wenjun Yang Zhaohui Yang Kai Ye Yuan-Nong Ye Li Yu Fangqing Zhao Yiqiang Zhao Weiwei Zhai Dandan Zhang Liye Zhang Houfeng Zheng Qi Zhou Tianqi Zhu Ya-ping Zhang Ruijin Hospital Shanghai Jiao Tong University College of Life Science and Technology Guangxi University Beijing Institute of Genomics Chinese Academy of Sciences Children's Hospital of Chongqing Medical University Wuxi School of Medicine Jiangnan University School of Biology and Biological Engineering South China University of Technology Department of Physics School of ScienceTianjin University School of Pharmaceutical Sciences Wuhan University Institute of Botany Chinese Academy of Sciences Institut Pasteur of Shanghai Chinese Academy of Sciences Institute of Biophysics Chinese Academy of Sciences Institute of Hydrobiology Chinese Academy of Sciences School of Life Sciences Sun Yat-sen University Institute of Synthetic Biology Shenzhen Institute of Advanced TechnologyChinese Academy of Sciences Faculty of Medicine and Health Sciences University College Sedaya International School of Medicine South China University of Technology Department of Medical Genetics Capital Institute of Pediatrics School of Life Science and Technology Harbin Institute of Technology Department of Biochemistry Abdul Wali Khan University Xiangya Hospital Central South University Department of Computer Science City University of Hong Kong College of Life Science and Technology Foshan University South China Sea Institute of Oceanology Chinese Academy of Sciences College of Ecology Lanzhou University School of Life Sciences and Technology Tongji University School of Life Sciences Peking University Kunming Institute of Zoology Chinese Academy of Sciences College of Animal Science South China Agricultural University Institute of Neuroscience Chinese Academy of Sciences School of Life Sciences East China Normal University Nanjing University of Aeronautics and Astronautics Wenzhou Institute University of Chinese Academy of Sciences Institute of Systems Biomedicine Shanghai Jiao Tong University Tongji Medical College Huazhong University of Science and Technology School of Life Sciences Xiamen University Division of Life Science and Department of

Recently, Worobey et al.(2022) published a report entitled ‘The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic' that succinctly summarizes their study [1]. A pre-print version of this study had earlier elicited a series of highprofile media coverages [2,3]. All these reports deliver a social-political message that the Huanan market is the epicenter of COVID-19.

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Sensing-Assisted Channel Estimation in ISAC systems 14th

Sensing-Assisted Channel Estimation in ISAC Systems

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14th EAI International Conference on Wireless and Satellite systems, WiSATS 2024

作者： Yin, Rui Shi, Yexin Qi, Wei Chen, Xianfu Wu, Celimuge Ji, Yusheng School of Information and Electrical Engineering Hangzhou City University Hangzhou310018 China College of Information Science and Electronic Engineering Zhejiang University Hangzhou310027 China Shenzhen CyberAray Network Technology Company Ltd Shenzhen China Graduate School of Informatics and Engineering The University of Electro-Communications Tokyo182-8585 Japan Information Systems Architecture Research Division National Institute of Informatics Tokyo101-8430 Japan

ISBN: (纸本)9783031862021

In future Sixth-Generation (6G) mobile communication, satellite communication is a crucial means of extending mobile networks worldwide. However, in satellite communication systems, the transmission capacity between ground stations and users has become a bottleneck for satellite communication systems. For this issue, Integrated Sensing and Communication (ISAC) technology and Artificial Intelligence (AI), which has been widely studied, has the potential to offer excellent solutions. This paper explores a Uformer-based sensing-assisted communication system that enhances channel estimation accuracy through the design of a Uformer-based channel estimation enhancement algorithm. By formulating a global optimization problem, we seek to improve resource efficiency through finding the optimal resource allocation schemes. Initially, the system utilizes radar data to obtain reconstructed channels and employs communication data for channel estimation. The proposed neural network model then fuses these data into a new and more accurate channel state information. Finally, we present a resource allocation algorithm and validate the performance of all proposed algorithms through simulations. © ICST institute for Computer sciences, Social Informatics and Telecommunications Engineering 2025.

关键词： Resource allocation

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Enabling technology and core theory of synthetic biology

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science China(Life sciences) 2023年第8期66卷 1742-1785页

作者： Xian-En Zhang Chenli Liu Junbiao Dai Yingjin Yuan Caixia Gao Yan Feng Bian Wu Ping Wei Chun You Xiaowo Wang Tong Si Faculty of Synthetic Biology Shenzhen Institute of Advanced TechnologyShenzhen 518055China Institute of Synthetic Biology Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China National Laboratory of Biomacromolecules Institute of BiophysicsChinese Academy of SciencesBeijing 100101China Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering(Ministry of Education) School of Chemical Engineering and TechnologyTianjin UniversityTianjin 300072China State Key Laboratory of Plant Cell and Chromosome Engineering Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China State Key Laboratory of Microbial Metabolism Shanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Microbial Resources Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China Tianjin Institute of Industrial Biotechnology Chinese Academy of SciencesTianjin 300308China Ministry of Education Key Laboratory of Bioinformatics Center for Synthetic and Systems BiologyBioinformatics DivisionBeijing National Research Center for Information Science and TechnologyDepartment of AutomationTsinghua UniversityBeijing 100084China

Synthetic biology provides a new paradigm for life science research(“build to learn”)and opens the future journey of biotechnology(“build to use”).Here,we discuss advances of various principles and technologies in the mainstream of the enabling technology of synthetic biology,including synthesis and assembly of a genome,DNA storage,gene editing,molecular evolution and de novo design of function proteins,cell and gene circuit engineering,cell-free synthetic biology,artificial intelligence(AI)-aided synthetic biology,as well as *** also introduce the concept of quantitative synthetic biology,which is guiding synthetic biology towards increased accuracy and predictability or the real rational *** conclude that synthetic biology will establish its disciplinary system with the iterative development of enabling technologies and the maturity of the core theory.

关键词： synthetic biology quantitative synthetic biology genome synthesis and assembly DNA storage molecular evolution de novo design computer-aided design cell engineering gene circuit chassis cell artificial intelligent(AI) biofoundry

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Incremental Learning with Pseudo Labels for Enhanced Glomeruli Segmentation Using SAM

Incremental Learning with Pseudo Labels for Enhanced Glomeru...

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2024 IEEE International Conference on E-Health Networking, Application and Services, HealthCom 2024

作者： Liu, Xinkai Peng, Boyuan Zhu, Xin Iwasaki, Tsuyoshi Sato, Atsuya Kazama, Junichiro James Huang, Jie Graduate Department of Computer Science and Engineering The University of Aizu Fukushima Aizu-Wakamatsu Japan Department of AI Technology Development M&D Data Science Center Institute of Science Tokyo Tokyo Japan Department of Nephrology and Hypertension Fukushima Medical University Fukushima Japan Graduate Department of Computer Science and Engineering Division of Information Systems The University of Aizu Fukushima Aizu-Wakamatsu Japan

ISBN: (纸本)9798350350548

The advent of the Segment Anything Model (SAM) marks a significant milestone in deep learning semantic segmentation tasks. In this study, an incremental learning model based on pseudo labels is proposed. The model generates bounding box prompts for SAM, enhancing the accuracy of glomeruli segmentation in renal pathology images. The model uses DenseNet-121 along with contrastive learning to enable self-supervised pre-training using mouse glomeruli images. Transfer learning is then conducted using labeled human renal pathology images to develop a binary classification model for glomeruli. Unlabeled images of human renal pathology are subsequently introduced for incremental learning. Class activation maps (CAMs) generated by the incremental learning model are post-processed to extract bounding rectangles for connected regions. These rectangles are then used as prompts for SAM segmentation. The proposed approach resulted in an average Dice similarity coefficient (DSC) of 0.825 in the glomeruli segmentation task. This result demonstrates the effectiveness of the incremental learning model and post-processing algorithms in improving SAM’s segmentation accuracy for renal pathology. © 2024 IEEE.

关键词： Contrastive Learning

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Improving Prediction Quality of Face Image Preference Using Combinatorial Fusion Algorithm 16th

Improving Prediction Quality of Face Image Preference Using...

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16th International Conference on Brain Informatics, BI 2023

作者： Zhang, Zihan Schweikert, Christina Shimojo, Shinsuke Hsu, D. Frank Laboratory of Informatics and Data Mining Department of Computer and Information Science Fordham University YorkNY10023 United States Division of Computer Science Mathematics and Science St. John’s University QueensNY11439 United States Division of Biology and Biological Engineering/Computation and Neural Systems California Institute of Technology PasadenaCA91125 United States

ISBN: (纸本)9783031430749

When two face images are shown to a subject, the subject’s preference choice is influenced by many factors. Although it is a challenging task, one way to detect a subject’s preference is to analyze the eye movement gaze cascade in the recorded video sequence together with a set of extracted attributes (features). Combinatorial fusion algorithm (CFA) is a new information fusion and machine learning paradigm for combining multiple scoring systems using rank-score characteristic (RSC) function and cognitive diversity (CD). In this paper, we apply CFA in the analysis of the eye movement gaze cascade sequence. In particular, we characterize each of the attributes and measure the diversity between two attributes using RSC function and CD respectively. The novelty of the combinatorial fusion approach is the new paradigm of incorporating both score function and rank function as well as using both score combination and rank combination. In addition, our results demonstrate that weighted rank combination has some advantage over weighted score combination when the weight is measured using diversity strength. Since diversity strength depends only on cognitive diversity between two attributes but not on any specific sequence in the eye movement gaze cascade, our result facilitates learning and modeling in an unsupervised manner. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.

关键词： information fusion

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Decentralized Optimal Merging Control for Mixed Traffic with Vehicle Inference

Decentralized Optimal Merging Control for Mixed Traffic with...

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American Control Conference (ACC)

作者： Wei Xiao Christos G. Cassandras Computer Science & Artificial Intelligence Lab Massachusetts Institute of Technology Cambridge MA USA Division of Systems Engineering and Center for Information and Systems Engineering Boston University Brookline MA USA

ISBN: (数字)9798350382655

ISBN: (纸本)9798350382662

This paper addresses the optimal control of vehicles arriving from two curved roads at a merging point where the objective is to jointly minimize the travel time, energy consumption, and passenger discomfort. Unlike prior work where traffic consists entirely of Connected and Automated Vehicles (CAVs), we consider optimal controls for CAVs in mixed traffic including Human-Driven Vehicles (HDVs) behaving according to some car-following model that includes random actions. The control applied to CAVs is based on partial information about the presence and states of HDVs which is inferred from local observations available to the CAVs. The passing order of HDVs at the merging point is determined and assisted by CAVs using a proposed Minimum-Effort Merging Contract (MEMC) that uses Control Barrier Functions (CBFs) to guarantee safety. A coordinator is used to manage both the CAV information and inferred HDV information such that the problem can still be solved in a decentralized way. Our approach first determines an analytically tractable unconstrained optimal solution. We then use the joint Optimal Control and Barrier Function (OCBF) method to obtain a controller which optimally tracks such a solution while also guaranteeing all safety and control constraints, including a safe merging contract between CAVs and HDVs. Simulation examples are included to compare the performance under different CAV penetration rates.

关键词： Energy consumption Rollover Roads Merging Optimal control Safety Contracts

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Femoropopliteal Artery Stent Detection in Fluoroscopy Using Otsu's Preprocessing and CNN Segmentation 4

Femoropopliteal Artery Stent Detection in Fluoroscopy Using ...

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4th International Conference on Technological Advancements in Computational sciences, ICTACS 2024

作者： Rajinikanth, Venkatesan Damaševičius, Robertas Taniar, David Saveetha School of Engineering Saveetha Institute of Medical and Technical Sciences Division of Research and Innovation Department of Computer Science and Engineering TN Chennai602105 India Kaunas University of Technology Centre of Real Time Computer Systems Kaunas44249 Lithuania Monash University Faculty of Information Technolog MelbourneVIC3800 Australia

ISBN: (纸本)9798350387490

Computer algorithm supported medical image analysis is a prevalent method in clinics, which effectively alleviates the diagnostic burden associated with traditional image assessment methods. This study aims to create a method that utilizes a Convolutional-Neural-Network (CNN) to accurately segment the Femoropopliteal Artery Stent (FAS) in Digital Fluoroscopy Images (DFI). In order to improve the accuracy of segmentation, this study used the combination of Otsu's tri-level thresholding and the Lévy-Flight Distribution Algorithm (LFDA). The suggested technique consists of many stages: collecting and resizing images and masks, boosting the DFI using Otsu and LFDA, using CNN-segmentation to extract the stent region, comparing segmented stent with mask, and calculating the required performance metrics. The efficacy of the suggested system is validated by analyzing the raw and thresholded DFI. The investigational results of this work affirm that this method achieves a higher level of accuracy (>96%) in segmenting images when the Otsu's preprocessed image is utilized. The experimental study employs the UNet-variants, and in the future, alternative CNN-segmentation methodologies can be utilized to validate the effectiveness of the presented scheme. © 2024 IEEE.

关键词： Convolutional neural networks

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Brownian-Distribution Algorithm Optimized Efficientnet Features for Normal/Glaucoma Retinal Fundus Image Classification 4

Brownian-Distribution Algorithm Optimized Efficientnet Featu...

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4th International Conference on Technological Advancements in Computational sciences, ICTACS 2024

ISBN: (纸本)9798350387490

The eye is a critical sensory organ in human physiology, and any abnormality in the eye will result in vision problems ranging from mild to severe. Image-guided methods are frequently employed to conduct clinical-level eye health assessments, and retinal fundus imaging (RFI) is among the most frequently employed modalities for eye analysis. This research aims to implement a Deep-Learning (DL)-based technique for classifying the Normal/Glaucoma RFI database. This scheme consist following phases, image collection and labelling, feature extraction with EfficientNet, feature optimization using a novel Brownian-Distribution Algorithm (BDA), and binary classification with 3-fold cross validation. Initially, the proposed approach performs the classification with EfficientNet-model features and documents the results. Subsequently, the BDA is employed to optimize the features in order to identify the most significant ones. Serial features-fusion is then implemented to generate a new features vector. The results of this study confirm that this approach is capable of achieving a 100 % accuracy rate when the BDA optimized feature vector is utilized for the classification task. In the future, this application may be utilized to analyze the RFI collected from hospital. © 2024 IEEE.

关键词： Ophthalmology

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Artificial Intelligence based Healthcare Knowledge Structure for Automatic Medical Report Generation 7

Artificial Intelligence based Healthcare Knowledge Structure...

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7th International Conference on Contemporary Computing and Informatics, IC3I 2024

作者： Kumar, Pramod Alghayadh, Faisal Yousef Tamta, Vinay Prasad Anand, Monika Soni, Mukesh Chaudhary, Jitendra Kumar Ganga Institute of Technology and Management Bhadana- Bahadurgarh Road Kablana Haryana Jhajjar India AlMaarefa University Computer Science and Information Systems Department College of Applied Sciences Riyadh Saudi Arabia Department of Information Technology Uttarakhand Srinagar India Chandigarh University Department Cse Punjab Mohali India Lovely Professional University Division of Research and Development Punjab Phagwara India Graphic Era Hill University School of Computing Bhimtal Campus Uttarakhand India

ISBN: (纸本)9798350350067

Automatic medical report production is a key text summarization application. Traditional text summarizing systems cannot completely interpret and use medical texts' complicated vocabulary due to the disparities between medical consultation data and general domain data. The crucial knowledge in medical consultations has not been successfully harnessed. Traditional text summary algorithms cannot automatically identify, and filter key information based on medical reports' structure and generate structured text. An AI-based knowledge-assisted structured medical report creation solution addresses these difficulties. This method uses entity-guided previous domain knowledge and structure-guided task decoupling to fully utilize medical consultation data and medical report structure. The suggested strategy improves ROUGE scores by 2% to 3% compared to similar methods, resulting in more accurate medical reports, according to IMCS21 dataset experiments. © 2024 IEEE.

关键词： Electronic health record

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Advanced UAV photogrammetry for precision 3D modeling in GPS denied inaccessible tunnels

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Safety in Extreme Environments 2024年第4期6卷 269-287页

作者： Ikeda, Hajime Bibish, Baterdene Fissha, Yewuhalashet Sinaice, Brian Bino Toriya, Hisatoshi Adachi, Tsuyoshi Kawamura, Youhei Department of Systems Control and Information Engineering National Institute of Technology Asahikawa College 2-2-1-6 Syunkodai Hokkaido Asahikawa-city 0718142 Japan Graduate School of International Resources Akita University 1-1 Tegatagakuen Machi Akita Akita-City 0108502 Japan Faculty of Engineering Division of Sustainable Resources Hokkaido University 13jyounishi8 Kita-ku Hokkaido Sapporo-City 0608628 Japan North China Institute of Science and Technology Hebei Langfang 065201 China

Unmanned Aerial Vehicles (UAVs) have evolved into potent tools for both researchers and professionals. Their use has expanded significantly in recent years across diverse fields of research and engineering, primarily owing to their image-capturing capabilities. These capabilities offer benefits such as time efficiency, cost-effectiveness, minimal fieldwork, and high precision. This study focuses on harnessing UAVs’ photogrammetric technology to create a reliable and accurate 3D modeling process. By doing so, we assess the feasibility of modeling and mapping hard-to-access tunnels using imagery acquired from UAVs combined with photogrammetry. This approach consistently provided a faithful representation of the environment under study. Three distinct experiments underpin this research. The first aims to construct a 3D model using a singular directional light source, evaluating its precision in a concrete tunnel setting. The second experiment involves crafting a 3D model of an underground sewer tunnel using both unidirectional and omnidirectional light sources. The final experiment leverages the insights from the preceding tests to create a 3D model via a specially-designed UAV system, gauging the accuracy of this 3D photogrammetric model within what is termed in this study as a "pedestrian tunnel." However, there are inherent challenges to this approach. For instance, augmenting a drone with additional equipment changes its weight distribution, potentially compromising its stability. An improperly balanced payload could result in uneven flight patterns, rendering the UAV harder to manage. © The Author(s) 2024.

关键词： Inaccessible tunnel mapping Payload balance challenges Photogrammetric analysis Subterranean 3D modeling Unmanned Aerial Vehicles (UAVs)

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