Modular composition of systems through defined input/output interfaces is a wide-spread engineering approach that allows to make the design of complicated systems tractable. Although this approach has percolated to th...
Modular composition of systems through defined input/output interfaces is a wide-spread engineering approach that allows to make the design of complicated systems tractable. Although this approach has percolated to the design of synthetic genetic circuits, it has proved challenging to obtain predictable design outcomes. In particular, context-dependence due to sharing a limited pool of cellular resources is a major factor that confounds modular composition of genetic modules. Here, we propose the use of a systems framework in which resource sharing among different subsystems is explicitly modeled through disturbance inputs and outputs. Within this system description, resource sharing results in undesired connectivity among subsystems, which is explicitly accounted for in design. Accordingly, we propose to use this system framework to co-design stable systems, with constant input, based on steady state specifications that each subsystem should satisfy. To this end, we provide sufficient conditions on the system parameters such that the output of each subsystem in the network remains in a small interval around a desired value, as well as an algorithmic procedure to compute the feasible region for these parameters. In general, this framework can be used to design subsystems to satisfy a specification, while explicitly accounting for context-dependence.
Circadian rhythms play a vital role in maintaining a person’s well-being but remain difficult to quantify accurately. Numerous approaches exist to measure these rhythms, but they often suffer from performance issues ...
Circadian rhythms play a vital role in maintaining a person’s well-being but remain difficult to quantify accurately. Numerous approaches exist to measure these rhythms, but they often suffer from performance issues on the individual level. This work implements a Steady-State Kalman Filter as a method for estimating the circadian phase shifts from biometric signals. Our framework can automatically fit the filter’s parameters to biometric data obtained for each individual, and we were able to consistently estimate the phase shift within 1 hour of melatonin estimates on 100% of all subjects in this study. The estimation method opens up the possibility of real-time control and assessment of the circadian system, as well as chronotherapeutic *** relevance— This establishes a near real-time alternative to melatonin measurements for the estimation of circadian phase shifts, with potential applications in feedback circadian control and chronotherapeutics
This paper presents a centralized model for operating multi-energy microgrids. The proposed model is based on a linearized optimal power flow (OPF) model for handling the network constraints in the distribution networ...
This paper presents a centralized model for operating multi-energy microgrids. The proposed model is based on a linearized optimal power flow (OPF) model for handling the network constraints in the distribution networks. It is assumed that each local microgrid is self-sustaining and can be operated independently from the other microgrids. However, the network access provides more flexibility to the multi-energy microgrid operators to supply their loads. The network-based electrical energy transactions are accepted in this study, while energy transformation from electricity to the other carriers is an asset to minimize the overall operating cost of the centralized multi-energy microgrid operation. The proposed model is tested and verified on the modified IEEE 33-bus test system.
Cortical visual prostheses are designed to treat blindness by restoring visual perceptions through artificial electrical stimulation of the primary visual cortex (V1). Intracortical microelectrodes produce the smalles...
Cortical visual prostheses are designed to treat blindness by restoring visual perceptions through artificial electrical stimulation of the primary visual cortex (V1). Intracortical microelectrodes produce the smallest visual percepts and thus higher resolution vision - like a higher density of pixels on a monitor. However, intracortical microelectrodes must maintain a minimum spacing to preserve tissue integrity. One solution to increase the density of percepts is to implant and stimulate multiple visual areas, such as V1 and V2, although the properties of microstimulation in V2 remain largely unexplored. We provide a direct comparison of V1 and V2 microstimulation in two common marmoset monkeys. We find similarities in response trends between V1 and V2 but differences in threshold, neural activity duration, and spread of activity at the threshold current. This has implications for using multi-area stimulation to increase the resolution of cortical visual prostheses.
This paper addresses the problem of Multi-Model Federated Learning (MMFL) in a typical wireless network, where a cellular Base Station (BS) cooperates with multiple clients to simultaneously train several Machine Lear...
This paper addresses the problem of Multi-Model Federated Learning (MMFL) in a typical wireless network, where a cellular Base Station (BS) cooperates with multiple clients to simultaneously train several Machine Learning (ML) models. Accordingly, the objective of this paper is to make an efficient joint decision for client association and communication-computation resource allocation to optimize the performance of the MMFL algorithm. In this regard, an optimization problem is formulated to minimize the average global loss of ML models under clients' energy and delay constraints. It is shown that the problem is a mixed-integer optimization whose objective is implicit in terms of the decision variables. To solve the optimization problem, we propose a Multi-Agent Multi-Model Federated Learning (MAMMFL) scheme based on a cooperative multi-agent configuration to intelligently assign models and resources to clients. Specifically, the problem is first converted to a Markov Decision Process (MDP) problem, then it is divided into four sub-MDP problems, where each problem relates to a phase in MMFL. The reinforcement learning algorithm solves each sub-problem, and a team-Q algorithm is adopted to coordinate agents in a cooperative multi-agent setting. Simulation results show that the proposed method can outperform other baselines in terms of average global loss and resource consumption.
Map-Reduce is a programming model and an associated implementation for processing and generating large data sets. This model has a single point of failure: the master, who coordinates the work in a cluster. On the con...
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In order to bolster the next generation of wireless networks, there has been a great deal of interest in non-terrestrial networks (NTN), including satellites, high altitude platform stations (HAPS), and uncrewed aeria...
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To achieve UN Sustainable Development Goal 7 (SDG7) by 2030, better rural electrification is required. Most current projects provide electricity inefficiently to rural users rather using stand-alone designs. As most r...
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Two-dimensional(2D)transition metal dichalcogenides(TMDCs)have attracted growing interest regarding their potential applications in next-generation electronic and optoelectronic *** to their atomic thickness and tunab...
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Two-dimensional(2D)transition metal dichalcogenides(TMDCs)have attracted growing interest regarding their potential applications in next-generation electronic and optoelectronic *** to their atomic thickness and tunable bandgap,they exhibit unique mechanical,electrical,and optical *** a specific member of the TMDC family,rhenium disulfide(ReS_(2))has stimulated intensive interest due to its anisotropic crystal structure,weak inter-layer coupling,and anisotropic electrical and optical *** this review,we summarize the distinct crystal structure and intrinsic anisotropic properties of ReS_(2),followed by an introduction to its synthesis *** current applications of ReS_(2)and its heterojunctions are presented based on its anisotropic *** review not only provides a timely summary of the current applications of ReS_(2)and its heterojunctions,but also inspires new approaches to develop other innovative devices based on 2D materials with a low lattice symmetry.
In this paper, we study the problem of promptly detecting the presence of non-cooperative activity from one or more Reconfigurable Intelligent Surfaces (RISs) with unknown characteristics lying in the vicinity of a Mu...
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