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Reuse of Domestic Wastewater by Membrane Technologies towards Sustainable City Development

IOP Conference Series: Earth and Environmental Science 2019年第1期248卷

作者： Nofiana S H Raharjo T Istirokhatun H Susanto Membrane Research Center (MeR-C) Integrated Laboratory for Research and Services Diponegoro University Semarang Indonesia Master Program of Environmental Science School of Postgraduate Studies Diponegoro University Semarang Indonesia Department of Environmental Engineering Faculty of Engineering Diponegoro University Semarang Indonesia Department of Chemical Engineering Faculty of Engineering Diponegoro University Semarang Indonesia Jl. Prof Soedarto SH Tembalang Semarang Indonesia

Supply of sustainable clean water is an activity that must be carried out towards smart cities. Nevertheless, the availability of water is decreasing both in quality and quantity. Wastewater including domestic wastewater is a potential source that can be reused as clean water supply dealing with water scarcity. This is due to domestic wastewater is produced continuously in large amount. In addition, reuse can reduce the total cost of handling wastewater. One modern technology that can be used for domestic wastewater treatment is membrane technology. Characteristics, various types, advantages, disadvantages, and challenges of membrane technology for domestic wastewater were discussed. This paper presents a review of domestic wastewater reuse by using membrane technology. More specifically this paper discusses domestic wastewater.

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Author Correction: Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations

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Nature medicine 2024年第12期30卷 3779页

作者： Sebastian Moguilner Sandra Baez Hernan Hernandez Joaquín Migeot Agustina Legaz Raul Gonzalez-Gomez Francesca R Farina Pavel Prado Jhosmary Cuadros Enzo Tagliazucchi Florencia Altschuler Marcelo Adrián Maito María E Godoy Josephine Cruzat Pedro A Valdes-Sosa Francisco Lopera John Fredy Ochoa-Gómez Alfredis Gonzalez Hernandez Jasmin Bonilla-Santos Rodrigo A Gonzalez-Montealegre Renato Anghinah Luís E d'Almeida Manfrinati Sol Fittipaldi Vicente Medel Daniela Olivares Görsev G Yener Javier Escudero Claudio Babiloni Robert Whelan Bahar Güntekin Harun Yırıkoğulları Hernando Santamaria-Garcia Alberto Fernández Lucas David Huepe Gaetano Di Caterina Marcio Soto-Añari Agustina Birba Agustin Sainz-Ballesteros Carlos Coronel-Oliveros Amanuel Yigezu Eduar Herrera Daniel Abasolo Kerry Kilborn Nicolás Rubido Ruaridh A Clark Ruben Herzog Deniz Yerlikaya Kun Hu Mario A Parra Pablo Reyes Adolfo M García Diana L Matallana José Alberto Avila-Funes Andrea Slachevsky María I Behrens Nilton Custodio Juan F Cardona Pablo Barttfeld Ignacio L Brusco Martín A Bruno Ana L Sosa Ortiz Stefanie D Pina-Escudero Leonel T Takada Elisa Resende Katherine L Possin Maira Okada de Oliveira Alejandro Lopez-Valdes Brian Lawlor Ian H Robertson Kenneth S Kosik Claudia Duran-Aniotz Victor Valcour Jennifer S Yokoyama Bruce Miller Agustin Ibanez Latin American Brain Health Institute Universidad Adolfo Ibañez Santiago de Chile Chile. Cognitive Neuroscience Center Universidad de San Andrés Buenos Aires Argentina. Department of Neurology Massachusetts General Hospital and Harvard Medical School Boston MA USA. Universidad de los Andes Bogota Colombia. Global Brain Health Institute (GBHI) University of California San Francisco CA USA. Global Brain Health Institute (GBHI) Trinity College Dublin Dublin Ireland. The University of California Santa Barbara (UCSB) Santa Barbara CA USA. Escuela de Fonoaudiología Universidad San Sebastián Santiago de Chile Chile. Grupo de Bioingeniería Decanato de Investigación Universidad Nacional Experimental del Táchira San Cristóbal Venezuela. Advanced Center for Electrical and Electronic Engineering Universidad Técnica Federico Santa María Valparaíso Chile. University of Buenos Aires Buenos Aires Argentina. The Clinical Hospital of Chengdu Brain Sciences Institute University of Electronic Sciences and Technology of China Chengdu China. Technology of China Chengdu China. Cuban Neuroscience Center La Habana Cuba. Grupo de Neurociencias de Antioquia (GNA) University of Antioquia Medellín Colombia. Department of Psychology Master Program of Clinical Neuropsychology Universidad Surcolombiana Neiva Neiva Colombia. Department of Psychology Universidad Cooperativa de Colombia Arauca Colombia. Neurocognition and Psychophysiology Laboratory Universidad Surcolombiana Neiva Colombia. Reference Center of Behavioural Disturbances and Dementia School of Medicine University of Sao Paulo Sao Paulo Brazil. Traumatic Brain Injury Cognitive Rehabilitation Out-Patient Center University of Sao Paulo Sao Paulo Brazil. Center for Social and Cognitive Neuroscience School of Psychology Universidad Adolfo Ibáñez Santiago Chile. Neuropsychology and Clinical Neuroscience Laboratory (LANNEC) Physiopathology Program-Institute of Biomedical Sciences (ICBM) Neuroscience and East Neuroscience Dep

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Author Correction: Siliceous zeolite-derived topology of amorphous silica

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Communications chemistry 2025年第1期8卷 23页

作者： Hirokazu Masai Shinji Kohara Toru Wakihara Yuki Shibazaki Yohei Onodera Atsunobu Masuno Sohei Sukenaga Koji Ohara Yuki Sakai Julien Haines Claire Levelut Philippe Hébert Aude Isambert David A Keen Masaki Azuma Department of Materials and Chemistry National Institute of Advanced Industrial Science and Technology 1-8-31 Midorigaoka Ikeda Osaka 563-8577 Japan. hirokazu.masai@aist.go.jp. Center for Basic Research on Materials National Institute for Materials Science 1-2-1 Sengen Tsukuba Ibaraki 305-0047 Japan. KOHARA.Shinji@nims.go.jp. Institute of Engineering Innovation The University of Tokyo Yayoi 2-11-16 Bunkyo-ku Tokyo 113-8656 Japan. Photon Factory Institute of Materials Structure Science High Energy Accelerator Research Organization (KEK) 1-1 Oho Tsukuba Ibaraki 305-0801 Japan. Institute for Integrated Radiation and Nuclear Science Kyoto University 2-1010 Asashiro-nishi Kumatori-cho Sennan-gun Osaka 590-0494 Japan. Center for Basic Research on Materials National Institute for Materials Science 1-2-1 Sengen Tsukuba Ibaraki 305-0047 Japan. Graduate School of Engineering Kyoto University Kyotodaigaku-katsura Nishikyo-ku Kyoto 615-8520 Japan. Institute of Multidisciplinary Research for Advanced Materials Tohoku University 2-1-1 Katahira Aoba-ku Sendai Miyagi 980-8577 Japan. Japan Synchrotron Radiation Research Institute (JASRI/SPring-8) Kouto Sayo-cho Hyogo 679-5198 Japan. Faculty Materials for Energy Shimane University 1060 Nishikawatsu-cho Matsue Shimane 690-8504 Japan. Kanagawa Institute of Industrial Science and Technology (KISTEC) 705-1 Shimoimaizumi Ebina Kanagawa 243-0435 Japan. Laboratory for Materials and Structures Tokyo Institute of Technology 4259 Nagatsuta Yokohama Kanagawa 226-8503 Japan. Institut Charles Gerhardt Montpellier CNRS Université de Montpellier ENSCM 34293 Cedex 5 Montpellier France. Laboratoire Charles Coulomb CNRS Université de Montpellier 34095 Montpellier France. CEA DAM Le Ripault F-37260 Monts France. Institut de Physique du Globe de Paris (IPGP) Université Paris Cité Paris France. ISIS Facility Rutherford Appleton Laboratory Harwell Campus Didcot Oxfordshire OX11 0QX UK.

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Lipid Bilayer Array: Rapid and Resilient Detection of Toxin Pore Formation Using a Lipid Bilayer Array (Small 49/2020)

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Small 2020年第49期16卷 2070268-2070268页

作者： Yoshihisa Ito Toshihisa Osaki Koki Kamiya Tetsuya Yamada Norihisa Miki Shoji Takeuchi Artificial Cell Membrane Systems Group Kanagawa Institute of Industrial Science and Technology 3‐2‐1 Sakado Takatsu‐ku Kawasaki Kanagawa 213‐0012 Japan Center for Multidisciplinary and Design Science School of Integrated Design Engineering Keio University 3‐14‐1 Hiyoshi Kohoku‐ku Yokohama Kanagawa 223‐8522 Japan Institute of Industrial Science The University of Tokyo 4‐6‐1 Komaba Meguro‐ku Tokyo 153‐8505 Japan Department of Mechanical Engineering Faculty of Science and Technology Keio University 3‐14‐1 Hiyoshi Kohoku‐ku Yokohama Kanagawa 223‐8522 Japan Department of Mechano‐Informatics Graduate School of Information Science and Technology The University of Tokyo 7‐3‐1 Hongo Bunkyo‐ku Tokyo 113–8656 Japan

In article number 2005550, Shoji Takeuchi and co‐workers present a parallel lipid bilayer array with integrating series resistors for sensitive and resilient detection of toxin pore formation, illustrated by electrical signatures. This array will help in understanding toxic activity and development of diagnosis, treatment, and control of bacterial infections in medicine.

关键词： electrophysiological analysis planar bilayer lipid membranes pore‐forming proteins stochastic process

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Scientists Against War: A Plea to World Leaders for Better Governance

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Sleep and vigilance 2022年第1期6卷 1-6页

作者： Seithikurippu R Pandi-Perumal Velayudhan Mohan Kumar Namasivayam Ganesh Pandian Joop T de Jong Sudalaikannu Andiappan Alexandru Corlateanu Arehally Marappa Mahalaksmi Saravana Babu Chidambaram Ramasamy Rajesh Kumar Chellamuthu Ramasubramanian Sudhakar Sivasubramaniam Alvhild Alette Bjørkum JosAnn Cutajar Michael Berk Ilya Trakht Anton Vrdoljak Miguel Meira E Cruz Harris A Eyre Janne Grønli Dainiel P Cardinali Andreas Maercker Willem A C M van de Put Jaswant Guzder Bjørn Bjorvatn Wietse A Tol Darío Acuña-Castroviejo Marie Meudec Charles M Morin Markku Partinen Corrado Barbui Mark J D Jordans Mario H Braakman Christine Knaevelsrud Ståle Pallesen Marit Sijbrandij Diego Andrés Golombek Colin A Espie Pim Cuijpers Hernán Andrés Marín Agudelo Koos van der Velden Bessel A van der Kolk Stevan E Hobfoll Walter L J M Devillé Michael Gradisar Dieter Riemann John Axelsson Gloria Benítez-King Robert D Macy Vitalii Poberezhets Samuel Ratnajeevan Herbert Hoole Rangaswamy Srinivasa Murthy Thomas Hegemann Andreas Heinz Jane Salvage Alexander C McFarlane Rob Keukens Harendra de Silva Cornelia Oestereich Jochen Wilhelm Michael von Cranach Klaus Hoffmann Matthias Klosinski Dinesh Bhugra Mary V Seeman Somnogen Canada Inc. College Street Toronto Canada. Saveetha Medical College and Hospitals Saveetha Institute of Medical and Technical Sciences Saveetha University Chennai India. Kerala Chapter National Academy of Medical Sciences (India) New Delhi India. Institute for Integrated Cell-Material Sciences (WPI-iCeMS) A210 Kyoto University Institute for Advanced Study Yoshida Ushinomiya-cho Sakyo-ku Kyoto 606-8501 Japan. Department of Cultural Psychiatry and Global Mental Health Amsterdam UMC Amsterdam The Netherlands. Boston University School of Medicine Boston USA. Department of Gandhian Studies and Ramalingar Philosophy School of Religions Philosophy and Humanist Thought Madurai Kamaraj University Madurai Tamil Nadu India. Department of Respiratory Medicine Nicolae Testemitanu State University of Medicine and Pharmacy Chisinau Moldova. Department of Pharmacology JSS College of Pharmacy JSS Academy of Higher Education and Research Mysuru 570015 India. Global Community Educational Foundation (NGCEF) 7 Peterlee Pl Hebersham NSW 2770 Australia. Division of Community Psychiatry M. S. Chellamuthu Trust and Research Foundation Madurai India. Department of Biotechnology Manonmaniam Sundaranar University Tirunelveli Tamil Nadu 627012 India. Department of Safety Chemistry and Biomedical Laboratory Sciences Faculty of Engineering and Science Western Norway University of Applied Sciences Kronstad Bergen Norway. Department of Gender and Sexualities Faculty for Social Wellbeing University of Malta Room # 114 Guze Cassar Pullicino Building Msida 2080 MSD Malta. Deakin University The Institute for Mental and Physical Health and Clinical Translation (IMPACT) School of Medicine Barwon Health Geelong Australia. Department of Medicine Columbia University New York NY USA. Faculty of Civil Engineering Architecture and Geodesy University of Mostar Kampus Sveučilišta Maticehrvatskeb. b 88000 Mostar Bosnia and Herzegovina. Centro Cardiovascular da Universidade de Lisboa

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Author Correction: A consensus protocol for functional connectivity analysis in the rat brain

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Nature neuroscience 2023年 2023 Apr 18页

作者： Joanes Grandjean Gabriel Desrosiers-Gregoire Cynthia Anckaerts Diego Angeles-Valdez Fadi Ayad David A Barrière Ines Blockx Aleksandra Bortel Margaret Broadwater Beatriz M Cardoso Marina Célestine Jorge E Chavez-Negrete Sangcheon Choi Emma Christiaen Perrin Clavijo Luis Colon-Perez Samuel Cramer Tolomeo Daniele Elaine Dempsey Yujian Diao Arno Doelemeyer David Dopfel Lenka Dvořáková Claudia Falfán-Melgoza Francisca F Fernandes Caitlin F Fowler Antonio Fuentes-Ibañez Clément M Garin Eveline Gelderman Carla E M Golden Chao C G Guo Marloes J A G Henckens Lauren A Hennessy Peter Herman Nita Hofwijks Corey Horien Tudor M Ionescu Jolyon Jones Johannes Kaesser Eugene Kim Henriette Lambers Alberto Lazari Sung-Ho Lee Amanda Lillywhite Yikang Liu Yanyan Y Liu Alejandra López-Castro Xavier López-Gil Zilu Ma Eilidh MacNicol Dan Madularu Francesca Mandino Sabina Marciano Matthew J McAuslan Patrick McCunn Alison McIntosh Xianzong Meng Lisa Meyer-Baese Stephan Missault Federico Moro Daphne M P Naessens Laura J Nava-Gomez Hiroi Nonaka Juan J Ortiz Jaakko Paasonen Lore M Peeters Mickaël Pereira Pablo D Perez Marjory Pompilus Malcolm Prior Rustam Rakhmatullin Henning M Reimann Jonathan Reinwald Rodrigo Triana Del Rio Alejandro Rivera-Olvera Daniel Ruiz-Pérez Gabriele Russo Tobias J Rutten Rie Ryoke Markus Sack Piergiorgio Salvan Basavaraju G Sanganahalli Aileen Schroeter Bhedita J Seewoo Erwan Selingue Aline Seuwen Bowen Shi Nikoloz Sirmpilatze Joanna A B Smith Corrie Smith Filip Sobczak Petteri J Stenroos Milou Straathof Sandra Strobelt Akira Sumiyoshi Kengo Takahashi Maria E Torres-García Raul Tudela Monica van den Berg Kajo van der Marel Aran T B van Hout Roberta Vertullo Benjamin Vidal Roël M Vrooman Victora X Wang Isabel Wank David J G Watson Ting Yin Yongzhi Zhang Stefan Zurbruegg Sophie Achard Sarael Alcauter Dorothee P Auer Emmanuel L Barbier Jürgen Baudewig Christian F Beckmann Nicolau Beckmann Guillaume J P C Becq Erwin L A Blezer Radu Bolbos Susann Boretius Sandrine Bouvard Eike Budinger Joseph D Buxbaum Diana Cash Victor Donders Institute for Brain Behaviour and Cognition Radboud University Nijmegen The Netherlands. joanes.grandjean@radboudumc.nl. Department for Medical Imaging Radboud University Medical Center Nijmegen The Netherlands. joanes.grandjean@radboudumc.nl. Cerebral Imaging Centre Douglas Mental Health University Institute Verdun QC Canada. Integrated Program in Neuroscience McGill University Montreal QC Canada. Bio-imaging Lab University of Antwerp Antwerp Belgium. µNEURO Research Centre of Excellence University of Antwerp Antwerp Belgium. Instituto de Neurobiología Universidad Nacional Autónoma de México Campus Juriquilla Querétaro Mexico. Biological and Biomedical Engineering McGill University Montreal QC Canada. McConnell Brain Imaging Centre McGill University Montreal QC Canada. Montreal Neurological Institute McGill University Montreal QC Canada. UMR INRAE/CNRS 7247 Physiologie des Comportements et de la Reproduction Physiologie de la reproduction et des comportements Centre de recherche INRAE de Nouzilly Tours France. Department of Neurology and Neurosurgery McGill University Montreal QC Canada. Center for Animal MRI University of North Carolina at Chapel Hill Chapel Hill NC USA. Department of Neurology University of North Carolina at Chapel Hill Chapel Hill NC USA. Biomedical Research Imaging Center University of North Carolina at Chapel Hill Chapel Hill NC USA. Preclinical MRI Champalimaud Research Champalimaud Centre for the Unknown Lisbon Portugal. Laboratoire des Maladies Neurodégénératives Molecular Imaging Research Center (MIRCen) Université Paris-Saclay Commissariat à l'Énergie Atomique et aux Énergies Alternatives (CEA) CNRS Fontenay-aux-Roses France. Departamento de Neurobiología Conductual y Cognitiva Instituto de Neurobiología Universidad Nacional Autónoma de México Campus Juriquilla Querétaro México. Translational Neuroimaging and Neural Control Group High-Field Magnetic Resonance Max Planck Institute for Biological Cyberneti

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Native diversity buffers against severity of non-native tree invasions ( vol 621,pg 773 , 2023 )

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NATURE 2023年第7982期622卷 E2-E2页

作者： Delavaux, Camille S. Crowther, Thomas W. Zohner, Constantin M. Robmann, Niamh M. Lauber, Thomas van den Hoogen, Johan Kuebbing, Sara Liang, Jingjing de-Miguel, Sergio Nabuurs, Gert-Jan Reich, Peter B. Abegg, Meinrad Yao, Yves C. Adou Alberti, Giorgio Zambrano, Angelica M. Almeyda Alvarado, Braulio Vilchez Alvarez-Davila, Esteban Alvarez-Loayza, Patricia Alves, Luciana F. Ammer, Christian Anton-Fernandez, Clara Araujo-Murakami, Alejandro Arroyo, Luzmila Avitabile, Valerio Aymard, Gerardo A. Baker, Timothy R. Balazy, Radomir Banki, Olaf Barroso, Jorcely G. Bastian, Meredith L. Bastin, Jean-Francois Birigazzi, Luca Birnbaum, Philippe Bitariho, Robert Boeckx, Pascal Bongers, Frans Bouriaud, Olivier Brancalion, Pedro H. S. Brandl, Susanne Brienen, Roel Broadbent, Eben N. Bruelheide, Helge Bussotti, Filippo Gatti, Roberto Cazzolla Cesar, Ricardo G. Cesljar, Goran Chazdon, Robin Chen, Han Y. H. Chisholm, Chelsea Cho, Hyunkook Cienciala, Emil Clark, Connie Clark, David Colletta, Gabriel D. Coomes, David A. Valverde, Fernando Cornejo Corral-Rivas, Jose J. Crim, Philip M. Cumming, Jonathan R. Dayanandan, Selvadurai de Gasper, Andre L. Decuyper, Mathieu Derroire, Geraldine DeVries, Ben Djordjevic, Ilija Dolezal, Jiri Dourdain, Aurelie Obiang, Nestor Laurier Engone Enquist, Brian J. Eyre, Teresa J. Fandohan, Adande Belarmain Fayle, Tom M. Feldpausch, Ted R. Ferreira, Leandro V. Fischer, Markus Fletcher, Christine Frizzera, Lorenzo Gamarra, Javier G. P. Gianelle, Damiano Glick, Henry B. Harris, David J. Hector, Andrew Hemp, Andreas Hengeveld, Geerten Herault, Bruno Herbohn, John L. Herold, Martin Hillers, Annika Coronado, Euridice N. Honorio Hui, Cang Ibanez, Thomas T. Amaral, Ieda Imai, Nobuo Jagodzinski, Andrzej M. Jaroszewicz, Bogdan Johannsen, Vivian Kvist Joly, Carlos A. Jucker, Tommaso Jung, Ilbin Karminov, Viktor Kartawinata, Kuswata Kearsley, Elizabeth Kenfack, David Kennard, Deborah K. Kepfer-Rojas, Sebastian Keppel, Gunnar Khan, Mohammed Latif Killeen, Timothy J. Kim, Hyun Seok Kitayama, Kanehiro Kohl, Michael Korju Institute of Integrative Biology ETH Zurich (Swiss Federal Institute of Technology) Zurich Switzerland Department of Genetics Evolution and Environment University College London London UK The Forest School at The Yale School of the Environment Yale University New Haven CT USA Department of Forestry and Natural Resources Purdue University West Lafayette IN USA Department of Agriculture Forestry and Bioresources Seoul National University Seoul South Korea Department of Crop and Forest Sciences University of Lleida Lleida Spain Joint Research Unit CTFC–AGROTECNIO–CERCA Solsona Spain Wageningen University and Research Wageningen The Netherlands World Agroforestry (ICRAF) Nairobi Kenya Department of Forest Resources University of Minnesota St Paul MN USA Hawkesbury Institute for the Environment Western Sydney University Penrith New South Wales Australia Institute for Global Change Biology and School for Environment and Sustainability University of Michigan Ann Arbor MI USA Swiss Federal Institute for Forest Snow and Landscape Research WSL Birmensdorf Switzerland UFR Biosciences University Félix Houphouët-Boigny Abidjan Côte d’Ivoire Department of Agricultural Food Environmental and Animal Sciences University of Udine Udine Italy Faculty of Science and Technology Free University of Bolzano Bolzano Italy Spatial Ecology and Conservation Laboratory Department of Tourism Recreation and Sport Management University of Florida Gainesville FL USA Forestry School Tecnológico de Costa Rica TEC Cartago Costa Rica Fundacion ConVida Universidad Nacional Abierta y a Distancia UNAD Medellin Colombia Field Museum of Natural Histiory Chicago IL USA Center for Tropical Research Institute of the Environment and Sustainability UCLA Los Angeles CA USA Silviculture and Forest Ecology of the Temperate Zones University of Göttingen Göttingen Germany Division of Forest and Forest Resources Norwegian Institute of Bioeconomy Research (NIBIO) Ås Norway Museo de Hi

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Utilization of pottery stone as a replacing material for vitreous ceramic sanitary ware production: A case study in Khon Kaen, Thailand 6th

Utilization of pottery stone as a replacing material for vit...

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6th KKU International engineering Conference, KKU-IENC 2016

作者： Sirilar, Pakawadee Srisukhumbowornchai, Nakorn Thanakijkasem, Purit Sirisoonthorn, Somnuk Klein, Gernot Program of Integrated Product Design and Manufacturing Division of Materials Technology School of Energy Environment and Materials King Mongkut's University of Technology Thonburi Bangkok10140 Thailand National Metal and Materials Technology Center National Science and Technology Development Agency Thailand Science Park Pathumthani12120 Thailand Faculty of Engineering University of Applied Sciences Koblenz Koblenz56203 Germany

ISBN: (纸本)9783035710045

The aim of this work was to determine the properties of vitreous ceramic sanitary ware bodies according to the production of Khon Kaen ceramic sanitary ware industry, Thailand. Pottery stone was used as a replacing material in the commercial ceramic sanitary ware body formulation. The cast slurry of seven formulations was prepared by wet milling. The rheological properties (density and torsion viscosity) were investigated before slip casting. The test pieces were fired at 1175, 1200 and 1225°C and the physical-mechanical properties (firing shrinkage, flexural strength, and water absorption) were compared. As a result, pottery stone shows a possibility to replace quartz in the production. It could enhance all of the good properties at lower firing temperature. Using of pottery stone could reduce production cost in term of energy fuel by 4.45% when compared with commercial formulation. © 2017 Trans Tech Publications.

关键词： Water absorption

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Global tracking of marine megafauna space use reveals how to achieve conservation targets

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Science (New York, N.Y.) 2025年第6751期388卷 1086-1097页

作者： Ana M M Sequeira Jorge P Rodríguez Sarah A Marley Hannah J Calich Mirjam van der Mheen Michelle VanCompernolle Lucy M Arrowsmith Lauren R Peel Nuno Queiroz Marisa Vedor Ivo da Costa Gonzalo Mucientes Ana Couto Nicolas E Humphries Sara Abalo-Morla Francisco J Abascal Debra L Abercrombie Katya Abrantes F Alberto Abreu-Grobois André S Afonso Pedro Afonso Heidi Ahonen Susanne Åkesson Joanna Alfaro-Shigueto Russel D Andrews Frédéric Angelier Marina Antonopoulou Javier A Arata Gonzalo Araujo Randall Arauz José Manuel Arcos Igor Arregui Haritz Arrizabalaga Marie Auger-Méthé Steffen Bach Fred Bailleul Robin W Baird George H Balazs Susan G Barco Adam Barnett Warren Baverstock Alastair M M Baylis Annalea Beard Juan Bécares Eduardo J Belda Ian Bell Ashley Bennison Scott R Benson Diego Bernal Michael L Berumen Sandra Bessudo Natalia P A Bezerra Antonin V Blaison Gabriela S Blanco Barbara A Block Mark Bolton Mark E Bond Ramón Bonfil Camrin D Braun Annette C Broderick Michael de L Brooke Annabelle M L Brooks Edward J Brooks Ignacio M Bruno Jennifer M Burns Michael E Byrne Steven E Campana Hamish A Campbell Richard A Campbell Aaron Carlisle Ruth H Carmichael Gemma Carroll Paolo Casale Filipe R Ceia Demian D Chapman Taylor K Chapple Jean-Benoit Charrassin Andre Chiaradia John Chisholm Christopher R Clarke Thomas A Clay Christophe Cleguer Elizabeth Clingham Eric E G Clua Jesse E M Cochran Rochelle Constantine Robert W Cooper Estelle Crochelet Michelle Cronin Eduardo Cuevas Kayla P DaCosta Laurent Dagorn Ryan Daly Randall W Davis P J Nico de Bruyn Carlos Delgado-Trejo Thomas Dellinger Solène Derville Stella Diamant Andrew DiMatteo Kara L Dodge Philip D Doherty Michael C Double Alistair D M Dove Thomas K Doyle Michael J Drew Lindsay L Dubbs Clinton A J Duffy Peter H Dutton Ewan W J Edwards Luke D Einoder Mark V Erdmann Eduardo Espinoza Nicole Esteban Ana Isabel Fagundes Chris Feare Steven H Ferguson Luciana C Ferreira Francesco Ferretti John Filmalter Brittany Finucci G Chris Fischer Richard J Fitzpatrick Jorge Fontes Angela Formia Division of Ecology and Evolution Research School of Biology The Australian National University Canberra (Australian Capital Territory) Australia. UWA Oceans Institute and the School of Biological Sciences The University of Western Australia Perth (Western Australia) Australia. Instituto de Física Interdisciplinar y Sistemas Complejos (IFISC) CSIC-UIB Palma de Mallorca Spain. Instituto Mediterráneo de Estudios Avanzados (IMEDEA) CSIC-UIB Esporles Illes Balears Spain. C.A. Illes Balears Universidad Nacional de Educación a Distancia (UNED) Palma Spain. Delegación Territorial en Illes Balears Agencia Estatal de Meteorología (AEMET) Muelle de Poniente s/n Palma Spain. Scotland's Rural College (SRUC) Craibstone Estate Bucksburn Aberdeen UK. Oceans Graduate School and the UWA Oceans Institute The University of Western Australia Perth (Western Australia) Australia. School of Engineering and the UWA Oceans Institute The University of Western Australia Perth (Western Australia) Australia. Department of Biodiversity Conservation and Attractions Biodiversity and Conservation Science Kensington (Western Australia) Australia. Save Our Seas Foundation Geneva Switzerland. The Manta Trust Catemwood House Norwood Lane Corscombe Dorset UK. Centro de Investigação em Biodiversidade e Recursos Genéticos (CIBIO) InBIO Laboratório Associado Campus de Vairão Universidade do Porto Vairão Portugal. BIOPOLIS Program in Genomics Biodiversity and Land Planning Campus de Vairao Vairão Portugal. Instituto de Investigaciones Marinas Consejo Superior de Investigaciones Científicas (IIM-CSIC) Vigo Pontevedra Spain. School of Biological Sciences University of Aberdeen Aberdeen UK. Biomathematics and statistics Scotland The kings building Edinburgh Scotland. Marine Biological Association (MBA) The Laboratory Citadel Hill Plymouth UK. Instituto de Investigación para la Gestión Integrada de Zonas Costeras Universitat Politècnica de València Gandia València Spain. Instituto Español de O

The recent Kunming-Montreal Global Biodiversity Framework (GBF) sets ambitious goals but no clear pathway for how zero loss of important biodiversity areas and halting human-induced extinction of threatened species will be achieved. We assembled a multi-taxa tracking dataset (11 million geopositions from 15,845 tracked individuals across 121 species) to provide a global assessment of space use of highly mobile marine megafauna, showing that 63% of the area that they cover is used 80% of the time as important migratory corridors or residence areas. The GBF 30% threshold (Target 3) will be insufficient for marine megafauna's effective conservation, leaving important areas exposed to major anthropogenic threats. Coupling area protection with mitigation strategies (e.g., fishing regulation, wildlife-traffic separation) will be essential to reach international goals and conserve biodiversity.

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Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

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Genomics 2020年第2期112卷 1223-1232页

作者： Jason Y Y Wong Han Zhang Chao A Hsiung Kouya Shiraishi Kai Yu Keitaro Matsuo Maria Pik Wong Yun-Chul Hong Jiucun Wang Wei Jie Seow Zhaoming Wang Minsun Song Hee Nam Kim I-Shou Chang Nilanjan Chatterjee Wei Hu Chen Wu Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Adeline Seow Neil E Caporaso Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Yang Yang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Qiuyin Cai Zhihua Yin Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda H Dean Hosgood Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Michiaki Kubo Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Jianxin Shi Lei Song Xing Hua Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Fusheng Wei Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Wu-Chou Su Yu-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Li-Hsin Chien Yong-Bing Xiang Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Kyoung-Mu Lee Batel Blechter Haixin Li Yu-Tang Gao Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Laurie Burdett Meredith Yeager Amy Hutchinson Sonja I Berndt Wei Wu Herbert Pang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu C H Kang Meng Zhu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Michael Hsin Ko-Yung Sit James Ho Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho Il Yoon Chien-Chung Lin In Kyu Park Ping Xu Yuzhuo Wang Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Tzu-Yu Chen Shih-Sheng Jiang Jie Liu Taiki Yamaji Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Division of Cancer Epidemiology and Genetics National Cancer Institute Bethesda MD USA. Electronic address: jason.wong@nih.gov. Division of Cancer Epidemiology and Genetics National Cancer Institute Bethesda MD USA. Institute of Population Health Sciences National Health Research Institutes Zhunan Taiwan. Division of Genome Biology National Cancer Center Research Institute Tokyo Japan. Division of Cancer Epidemiology and Prevention Aichi Cancer Center Research Institute Nagoya Japan Department of Cancer Epidemiology Nagoya University Graduate School of Medicine Nagoya Japan. Department of Pathology Queen Mary Hospital The University of Hong Kong Hong Kong. Department of Preventive Medicine Seoul National University College of Medicine Seoul Republic of Korea. Ministry of Education Key Laboratory of Contemporary Anthropology School of Life Sciences Fudan University Shanghai China State Key Laboratory of Genetic Engineering School of Life Sciences Fudan University Shanghai China. Saw Swee Hock School of Public Health National University of Singapore Singapore. Cancer Genomics Research Laboratory Leidos Biomedical Research Inc Gaithersburg MD USA Department of Computational Biology St. Jude Children's Research Hospital Memphis TN USA. Division of Cancer Epidemiology and Genetics National Cancer Institute Bethesda MD USA Department of Statistics Sookmyung Women's University Seoul Republic of Korea. Department of Preventive Medicine Chonnam National University Medical School Gwangju Republic of Korea. National Institute of Cancer Research National Health Research Institutes Zhunan Taiwan. Bloomberg School of Public Health Johns Hopkins University Baltimore MD USA. Department of Etiology & Carcinogenesis and State Key Laboratory of Molecular Oncology Cancer Institute and Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China. Division of Thoracic Surgery Kinki University School of Medicine Sayama Japan. Division of

We investigated whether genetic susceptibility to tuberculosis (TB) influences lung adenocarcinoma development among never-smokers using TB genome-wide association study (GWAS) results within the Female Lung Cancer Consortium in Asia. Pathway analysis with the adaptive rank truncated product method was used to assess the association between a TB-related gene-set and lung adenocarcinoma using GWAS data from 5512 lung adenocarcinoma cases and 6277 controls. The gene-set consisted of 31 genes containing known/suggestive associations with genetic variants from previous TB-GWAS. Subsequently, we followed-up with Mendelian Randomization to evaluate the association between TB and lung adenocarcinoma using three genome-wide significant variants from previous TB-GWAS in East Asians. The TB-related gene-set was associated with lung adenocarcinoma (p = 0.016). Additionally, the Mendelian Randomization showed an association between TB and lung adenocarcinoma (OR = 1.31, 95% CI: 1.03, 1.66, p = 0.027). Our findings support TB as a causal risk factor for lung cancer development among never-smoking Asian women.

关键词： Lung adenocarcinoma Lung cancer Mendelian randomization Pathway analysis Tuberculosis

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