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arXiv 2021年

作者： Lutter, Michael Belousov, Boris Mannor, Shie Fox, Dieter Garg, Animesh Peters, Jan Intelligent Autonomous Systems group Computer Science Department Technical University of Darmstadt Darmstadt Germany Andrew and Erna Viterbi Faculty of Electrical & Computer Engineering Technion – Israel Institute of Technology and a Distinguished Scientist at NVIDIA Tel Aviv Israel Allen School of Computer Science & Engineering University of Washington and Senior Director of Robotics Research NVIDIA Washington Seattle United States Computer Science Department University of Toronto NVIDIA Toronto Canada

Solving the Hamilton-Jacobi-Bellman equation is important in many domains including control, robotics and economics. Especially for continuous control, solving this differential equation and its extension the Hamilton-Jacobi-Isaacs equation, is important as it yields the optimal policy that achieves the maximum reward on a give task. In the case of the Hamilton-Jacobi-Isaacs equation, which includes an adversary controlling the environment and minimizing the reward, the obtained policy is also robust to perturbations of the dynamics. In this paper we propose continuous fitted value iteration (cFVI) and robust fitted value iteration (rFVI). These algorithms leverage the non-linear control-affine dynamics and separable state and action reward of many continuous control problems to derive the optimal policy and optimal adversary in closed form. This analytic expression simplifies the differential equations and enables us to solve for the optimal value function using value iteration for continuous actions and states as well as the adversarial case. Notably, the resulting algorithms do not require discretization of states or actions. We apply the resulting algorithms to the Furuta pendulum and cartpole. We show that both algorithms obtain the optimal policy. The robustness Sim2Real experiments on the physical systems show that the policies successfully achieve the task in the real-world. When changing the masses of the pendulum, we observe that robust value iteration is more robust compared to deep reinforcement learning algorithm and the non-robust version of the algorithm. Videos of the experiments are shown at https://***/view/rfvi Copyright © 2021, The Authors. All rights reserved.

关键词： Dynamic programming

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CertainOdom: Uncertainty Weighted Multi-task Learning Model for LiDAR Odometry Estimation

CertainOdom: Uncertainty Weighted Multi-task Learning Model ...

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IEEE International Conference on robotics and Biomimetics

作者： Leyuan Sun Guanqun Ding Yusuke Yoshiyasu Fumio Kanehiro Department of Intelligent and Mechanical Interaction Systems Graduate School of Science and Technology University of Tsukuba Tsukuba Ibaraki Japan CNRS-AIST Joint Robotics Laboratory (JRL) IRL National Institute of Advanced Industrial Science and Technology (AIST). Digital Architecture Research Center (DARC) National Institute of Advanced Industrial Science and Technology (AIST) Tokyo Japan Computer Vision Research Team Artificial Intelligence Research Center (AIRC) National Institute of Advanced Industrial Science and Technology (AIST) Japan

ISBN: (纸本)9781665481106

As a basic and indispensable module, LiDAR odom-etry estimation is widely used in robotics. In recent years, learning-based modeling approaches for odometry estimation have been validated to be feasible. However, it is necessary to consider security factors as the highest priorities when we apply the learning-based model to certain high-risk real-world scenarios, such as autonomous driving. The odometry uncertainty estimation provides more valuable information for downstream tasks, such as route planning and navigation. In this paper, we propose an end-to-end neural network (namely CertainOdom) to solve odometry and uncertainty estimation tasks by applying multi-task learning. Instead of using the manually-tuned hyper-parameters, we employ the learnable uncertainties to weigh the balance between the error of translation and orientation in the loss function. We evaluate the estimated trajectory and uncertainty on KITTI dataset. We also compare the robustness against the traditional geometry-based methods on our artificially degraded KITTI LiDAR dataset. Extensive experimental results show that our model with uncertainty weighted loss achieves competitive performance in LiDAR odometry estimation. We also explain our uncertainties qualitatively and quantitatively.

关键词： Uncertainty Laser radar Biological system modeling Estimation Multitasking Robustness Trajectory

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Application of Graph-Curvature Features in Auxiliary Diagnosis for Histopathological Image Identification of Gastric Cancer

SSRN

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SSRN 2023年

作者： He, Ruilin Li, Chen Yang, Xinyi Yang, Jinzhu Jiang, Tao Grzegorzek, Marcin Sun, Hongzan Microscopic Image and Medical Image Analysis Group College of Medicine and Biological Information Engineering Northeastern University Shenyang China Key Laboratory of Intelligent Computing in Medical Image Ministry of Education Northeastern University Liaoning Shenyang China School of Intelligent Medicine Chengdu University of Traditional Chinese Medicine Chengdu China International Joint Institute of Robotics and Intelligent Systems Chengdu University of Information Technology Chengdu China Institute for Medical Informatics University of Luebeck Luebeck Germany Department of Knowledge Engineering University of Economics in Katowice Katowice Poland Shengjing Hospital of China Medical University Shenyang China School of Computer Science and Engineering

Background: Histopathology diagnosis is often regarded as the final diagnostic method for malignant tumors, but it has some drawbacks. This paper explores a computer-aided diagnostic method that can identify benign and malignant gastric cancer with histopathology images. Method: This article obtains the most suitable process through multiple experiments, compared multiple methods and features for classification. Firstly, the U-net is applied to segment the image. Next, the nucleus is extracted from the segmented image and the Minimum Spanning Tree (MST) diagram structure is drawn. The third step is to extract the graph-curvature features of histopathology image according to the MST image. Finally, by inputting graph-curvature features into the classifier, the recognition results for benign or malignant can be obtained. Result: During the experiment, we use various methods for comparison. In the image segmentation stage, U-net, watershed algorithm and Otsu threshold segmentation methods are used respectively. Combined with multiple indicators, we find that the U-net method is the most suitable for segmentation of histopathology images. In the feature extraction stage, in addition to extracting graph-edge feature and graph-curvature feature, several basic image features are also extracted, including Red, Green, Blue feature, Gray-Level Co-occurrence Matrix feature, Histogram of Oriented Gradient feature, and Local Binary Pattern feature. In the classifier design stage, we experimented with various methods, such as Support vector machine (SVM), Random forest, Artificial Neural Network, K Nearest Neighbors, VGG-16 and Inception-V3. Through the comparison and analysis, the classification results with an accuracy of 98.57% can be obtained by inputting the graph-curvature feature into SVM classifier. Conclusion: This paper has created a unique feature, graph-curvature feature based on MST to represent and analyze histopathology images. This graph-based feature can be used

关键词： Local binary pattern

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Efficient MedSAMs: Segment Anything in Medical Images on Laptop

arXiv

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arXiv 2024年

作者： Ma, Jun Li, Feifei Kim, Sumin Asakereh, Reza Le, Bao-Hiep Nguyen-Vu, Dang-Khoa Pfefferle, Alexander Wei, Muxin Gao, Ruochen Lyu, Donghang Yang, Songxiao Purucker, Lennart Marinov, Zdravko Staring, Marius Lu, Haisheng Dao, Thuy Thanh Ye, Xincheng Li, Zhi Brugnara, Gianluca Vollmuth, Philipp Foltyn-Dumitru, Martha Cho, Jaeyoung Mahmutoglu, Mustafa Ahmed Bendszus, Martin Pflüger, Irada Rastogi, Aditya Ni, Dong Yang, Xin Zhou, Guang-Quan Wang, Kaini Heller, Nicholas Papanikolopoulos, Nikolaos Weight, Christopher Tong, Yubing Udupa, Jayaram K. Patrick, Cahill J. Wang, Yaqi Zhang, Yifan Contijoch, Francisco McVeigh, Elliot Ye, Xin He, Shucheng Haase, Robert Pinetz, Thomas Radbruch, Alexander Krause, Inga Kobler, Erich He, Jian Tang, Yucheng Yang, Haichun Huo, Yuankai Luo, Gongning Kushibar, Kaisar Amankulov, Jandos Toleshbayev, Dias Mukhamejan, Amangeldi Egger, Jan Pepe, Antonio Gsaxner, Christina Luijten, Gijs Fujita, Shohei Kikuchi, Tomohiro Wiestler, Benedikt Kirschke, Jan S. de la Rosa, Ezequiel Bolelli, Federico Lumetti, Luca Grana, Costantino Xie, Kunpeng Wu, Guomin Puladi, Behrus Martín-Isla, Carlos Lekadir, Karim Campello, Victor M. Shao, Wei Brisbane, Wayne Jiang, Hongxu Wei, Hao Yuan, Wu Li, Shuangle Zhou, Yuyin Wang, Bo AI Collaborative Centre University Health Network Department of Laboratory Medicine and Pathobiology University of Toronto Vector Institute Toronto Canada Peter Munk Cardiac Centre University Health Network Toronto Canada Toronto General Hospital Research Institute University Health Network Department of Computer Science University of Toronto University Health Network Vector Institute Toronto Canada University of Science Vietnam National University Ho Chi Minh City Viet Nam Institute of Computer Science University of Freiburg Freiburg Germany School of Medicine and Health Harbin Institute of Technology Harbin China Division of Image Processing Department of Radiology Leiden University Medical Center Leiden Netherlands Department of System and Control Engineering School of Engineering Institute of Science Tokyo Formerly Tokyo Institute of Technology Tokyo Japan Institute for Anthropomatics and Robotics Karlsruhe Institute of Technology Karlsruhe Germany School of Information and Communication Engineering University of Electronic Science and Technology of China Chengdu China School of Electrical Engineering and Computer Science University of Queensland Brisbane Australia School of Cyberspace Hangzhou Dianzi University Hangzhou China Division for Computational Radiology and Clinical AI The Department of Neuroradiology University Hospital Bonn Germany Division for Computational Radiology and Clinical AI The Department of Neuroradiology University Hospital Bonn Germany Department of Neuroradiology Heidelberg University Hospital Heidelberg Germany Division for Computational Radiology and Clinical AI Department of Neuroradiology University Hospital Bonn Germany School of Biomedical Engineering Shenzhen University Shenzhen China School of Biological Science and Medical Engineering Southeast University Nanjing China Department of Urology Cleveland Clinic Cleveland United States Department of Computer Science University of Minnesota Minneapolis United St

Promptable segmentation foundation models have emerged as a transformative approach to addressing the diverse needs in medical images, but most existing models require expensive computing, posing a big barrier to their adoption in clinical practice. In this work, we organized the first international competition dedicated to promptable medical image segmentation, featuring a large-scale dataset spanning nine common imaging modalities from over 20 different institutions. The top teams developed lightweight segmentation foundation models and implemented an efficient inference pipeline that substantially reduced computational requirements while maintaining state-of-the-art segmentation accuracy. Moreover, the post-challenge phase advanced the algorithms through the design of performance booster and reproducibility tasks, resulting in improved algorithms and validated reproducibility of the winning solution. Furthermore, the best-performing algorithms have been incorporated into the open-source software with a user-friendly interface to facilitate clinical adoption. The data and code are publicly available to foster the further development of medical image segmentation foundation models and pave the way for impactful real-world applications. © 2024, CC BY-NC-SA.

关键词： Open source software

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Placental Vessel Segmentation and Registration in Fetoscopy: Literature Review and MICCAI FetReg2021 Challenge Findings

arXiv

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arXiv 2022年

作者： Bano, Sophia Casella, Alessandro Vasconcelos, Francisco Qayyum, Abdul Benzinou, Abdesslam Mazher, Moona Meriaudeau, Fabrice Lena, Chiara Cintorrino, Ilaria Anita De Paolis, Gaia Romana Biagioli, Jessica Grechishnikova, Daria Jiao, Jing Bai, Bizhe Qiao, Yanyan Bhattarai, Binod Gaire, Rebati Raman Subedi, Ronast Vazquez, Eduard Plotka, Szymon Lisowska, Aneta Sitek, Arkadiusz Attilakos, George Wimalasundera, Ruwan David, Anna L. Paladini, Dario Deprest, Jan De Momi, Elena Mattos, Leonardo S. Moccia, Sara Stoyanov, Danail Department of Computer Science University College London United Kingdom Department of Advanced Robotics Istituto Italiano di Tecnologia Italy Department of Electronics Information and Bioengineering Politecnico di Milano Italy The BioRobotics Institute Department of Excellence in Robotics and AI Scuola Superiore Sant'Anna Italy Fetal Medicine Unit Elizabeth Garrett Anderson Wing University College London Hospital United Kingdom EGA Institute for Women's Health Faculty of Population Health Sciences University College London United Kingdom Department of Development and Regeneration University Hospital Leuven Belgium Department of Fetal and Perinatal Medicine Istituto Giannina Gaslini Italy ENIB UMR CNRS 6285 LabSTICC 29238 France Department of Computer Engineering and Mathematics University Rovira i Virgili Spain ImViA Laboratory University of Bourgogne Franche-Comté France Physics Department Lomonosov Moscow State University Russia Fudan University China Medical Computer Vision and Robotics Group Department of Mathematical and Computational Sciences University of Toronto Canada Co. Ltd China NepAL Applied Mathematics and Informatics Institute for Research Nepal Redev Technology United Kingdom Sano Center for Computational Medicine Poland Quantitative Healthcare Analysis Group Informatics Institute University of Amsterdam Amsterdam Netherlands Center for Advanced Medical Computing and Simulation Massachusetts General Hospital Harvard Medical School BostonMA United States

Fetoscopy laser photocoagulation is a widely adopted procedure for treating Twin-to-Twin Transfusion Syndrome (TTTS). The procedure involves photocoagulation pathological anastomoses to restore a physiological blood exchange among twins. The procedure is particularly challenging, from the surgeon's side, due to the limited field of view, poor manoeuvrability of the fetoscope, poor visibility due to amniotic fluid turbidity, and variability in illumination. These challenges may lead to increased surgery time and incomplete ablation of pathological anastomoses, resulting in persistent TTTS. computer-assisted intervention (CAI) can provide TTTS surgeons with decision support and context awareness by identifying key structures in the scene and expanding the fetoscopic field of view through video mosaicking. Research in this domain has been hampered by the lack of high-quality data to design, develop and test CAI algorithms. Through the Fetoscopic Placental Vessel Segmentation and Registration (FetReg2021) challenge, which was organized as part of the MICCAI2021 Endoscopic vision (EndoVis) challenge, we released the first large-scale multi-center TTTS dataset for the development of generalized and robust semantic segmentation and video mosaicking algorithms with a focus on creating drift-free mosaics from long duration fetoscopy videos. For this challenge, we released a dataset of 2060 images, pixel-annotated for vessels, tool, fetus and background classes, from 18 in-vivo TTTS fetoscopy procedures and 18 short video clips of an average length of 411 frames for developing placental scene segmentation and frame registration for mosaicking techniques. Seven teams participated in this challenge and their model performance was assessed on an unseen test dataset of 658 pixel-annotated images from 6 fetoscopic procedures and 6 short clips. The challenge provided an opportunity for creating generalized solutions for fetoscopic scene understanding and mosaicking. In this paper,

关键词： Pixels

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Self-supervised linear motion deblurring

arXiv

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arXiv 2020年

作者： Liu, Peidong Janai, Joel Pollefeys, Marc Sattler, Torsten Geiger, Andreas Computer Vision and Geometry Group Department of Computer Science ETH Zürich Switzerland Autonomous Vision Group Max Planck Institute for Intelligent Systems Univeristy of Tübingen Tübingen Germany Microsoft Mixed Reality and Artificial Intelligence Lab Zürich Switzerland Computer Vision and Medical Image Analysis Group Chalmers University of Technology Sweden

Motion blurry images challenge many computer vision algorithms, e.g., feature detection, motion estimation, or object recognition. Deep convolutional neural networks are state-of-the-art for image deblurring. However, obtaining training data with corresponding sharp and blurry image pairs can be difficult. In this paper, we present a differentiable reblur model for self-supervised motion deblurring, which enables the network to learn from real-world blurry image sequences without relying on sharp images for supervision. Our key insight is that motion cues obtained from consecutive images yield sufficient information to inform the deblurring task. We therefore formulate deblurring as an inverse rendering problem, taking into account the physical image formation process: we first predict two deblurred images from which we estimate the corresponding optical flow. Using these predictions, we re-render the blurred images and minimize the difference with respect to the original blurry inputs. We use both synthetic and real dataset for experimental evaluations. Our experiments demonstrate that self-supervised single image deblurring is really feasible and leads to visually compelling results. Both the code and datasets are available at https://***/ethliup/SelfDeblur. Copyright © 2020, The Authors. All rights reserved.

关键词： Image enhancement

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Bitcoin Price Forecasting: A Comparative Study Between Statistical and Machine Learning Methods

Bitcoin Price Forecasting: A Comparative Study Between Stati...

引用

International Conference on computer & Information science (ICCIS)

作者： Waddah Waheeb Habib Shah Mohammed Jabreel Domenec Puig School of Computing Asia Pacific University of Technology & Innovation Kuala Lumpur Bukit Jalil Malaysia College of Computer Science King Khalid University Abha Saudi Arabia IRCV - Intelligent Robotics and Computer Vision Group Universitat Rovira i Virgili Tarragona Spain

ISBN: (数字)9781728154671

ISBN: (纸本)9781728154688

This paper presents a comparative study between statistical and machine learning methods in forecasting Bitcoin's closing prices. Thirteen forecasting methods namely average, naive, drift, auto-regressive integrated moving-average, simple exponential smoothing (SES), Holt, and damped exponential smoothing, the average of SES, Holt and damped methods, exponential smoothing (ETS), bagged ETS, Theta, multilayer perceptron, and extreme learning machines (ELM) were used to forecast the closing prices for the next 14 days. The findings of this study are three folds. First, there are seven forecasting methods outperformed the naive method namely MLP, ELM, damped exponential smoothing, simple exponential smoothing, Theta, ETS, and ARIMA. Second, MLP and ELM showed better forecasting accuracy on both validation and out-of-sample data among the forecasting methods used in this study. Third, the size of the training data is essential factor that should be considered when training forecasting methods.

关键词： Forecasting Bitcoin Training data Smoothing methods Training Time series analysis Support vector machines

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OTE: Optimal Trustworthy EdgeAI solutions for smart cities

OTE: Optimal Trustworthy EdgeAI solutions for smart cities

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IEEE/ACM International Symposium on Cluster Computing and the Grid (CCGRID)

作者： Vasileios Mygdalis Lorenzo Carnevale Jose Ramiro Martí nez-De-Dios Dmitriy Shutin Giovanni Aiello Massimo Villari Ioannis Pitas Department of Informatics Aristotle University of Thessaloniki Thessaloniki Greece Department of Mathematical and Computer Science Physics and Hearth Sciences University of Messina Messina Italy Gruppo Nazionale per il Calcolo Scientifico (GNCS) Istituto Nazionale di Alta Matematica (INdAM) &#x201C F. Severi&#x201D Rome Italy Robotics Vision and Control Group University of Seville Seville Spain Institute of Communications and Navigation German Aerospace Center (DLR) Wessling Germany Research and Development Lab. Engineering Ingegneria Informatica S.p.A Rome Italy

This work studies and defines the problem of providing extensive and opportunistic Edge AI-based area coverage in smart city application scenarios, by researching and determining the optimal configuration of sensing and computational resources for minimizing the environmental/technology footprint of the solution. A typical smart city computing continuum consists of statically installed multimodal sensing Internet-of-Things (IoT) nodes at various city locations, accompanied by interconnected computational Cloud/Edge/IoT nodes. This paper presents Optimal Trustworthy EdgeAI (OTE), an entirely novel research pipeline, that complements existing smart city infrastructure with intelligent drone Edge/IoT nodes (in the form of modularly equipped unmanned aerial vehicles), capable of autonomous repositioning according to individual/collective sensing and coverage criteria. Thereby, we envisage the emerging cutting-edge technologies of trustworthy sensing, perceiving, modelling technologies for predicting the behavior of moving targets (e.g., citizens/vehicles/objects), understanding natural phenomena (e.g., sea wave motion, urban flora/fauna, biodiversity) in order to anticipate events (people's bad habits, environmental changes), by exploiting novel continuous data processing services across the whole span of the enhanced Cloud-Edge-IoT computing continuum.

关键词： Cloud computing Privacy Smart cities Pipelines Semantics Robot sensing systems Software

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Analysing the direction of emotional influence in nonverbal dyadic communication: A facial-expression study

arXiv

引用

arXiv 2020年

作者： Shadaydeh, Maha Müller, Lea Schneider, Dana Thümmel, Martin Kessler, Thomas Denzler, Joachim Computer Vision Group Department of Mathematics and Computer Science Friedrich Schiller University of Jena Ernst-Abbe-Platz 2 Jena07743 Germany Max Planck Institute for Intelligent Systems Max-Planck-Ring 4 Tübingen72076 Germany Department of Social Psychology Friedrich Schiller University of Jena Humboldtstrasse 26 Jena07743 Germany

Identifying the direction of emotional influence in a dyadic dialogue is of increasing interest in the psychological sciences with applications in psychotherapy, analysis of political interactions or interpersonal conflict behavior. Facial expressions are widely described as being automatic and thus hard to overtly influence. As such, they are a perfect measure for a better understanding of unintentional behavior cues about social-emotional cognitive processes. With this view, this study is concerned with the analysis of the direction of emotional influence in dyadic dialogue based on facial expressions only. We exploit computer vision capabilities along with causal inference theory for quantitative verification of hypotheses on the direction of emotional influence, i.e., causal effect relationships, in dyadic dialogues. We address two main issues. First, in a dyadic dialogue, emotional influence occurs over transient time intervals and with intensity and direction that are variant over time. To this end, we propose a relevant interval selection approach that we use prior to causal inference to identify those transient intervals where causal inference should be applied. Second, we propose to use fine-grained facial expressions that are present when strong distinct facial emotions are not visible. To specify the direction of influence, we apply the concept of Granger causality to the time series of facial expressions over selected relevant intervals. We tested our approach on newly, experimentally obtained data. Based on quantitative verification of hypotheses on the direction of emotional influence, we were able to show that the proposed approach is most promising to reveal the causal effect pattern in various instructed interaction conditions. © 2020, CC BY.

关键词： Statistical tests

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REFUGE2 CHALLENGE: A TREASURE TROVE FOR MULTI-DIMENSION ANALYSIS AND EVALUATION IN GLAUCOMA SCREENING

arXiv

引用

arXiv 2022年

作者： Fang, Huihui Li, Fei Wu, Junde Fu, Huazhu Sun, Xu Son, Jaemin Yu, Shuang Zhang, Menglu Yuan, Chenglang Bian, Cheng Lei, Baiying Zhao, Benjian Xu, Xinxing Li, Shaohua Fumero, Francisco Sigut, José Almubarak, Haidar Bazi, Yakoub Guo, Yuanhao Zhou, Yating Baid, Ujjwal Innani, Shubham Guo, Tianjiao Yang, Jie Orlando, José Ignacio Bogunović, Hrvoje Zhang, Xiulan Xu, Yanwu The REFUGE2 Challenge Australia State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science Guangzhou China Intelligent Healthcare Unit Baidu Inc. Beijing China The Institute of High Performance Computing Agency for Science Technology and Research Singapore Yatiris Group PLADEMA Institute CONICET UNICEN Tandil Argentina Christian Doppler Lab for Artificial Intelligence in Retina Department of Ophthalmology and Optometry Medical University of Vienna Vienna Austria VUNO Inc Seoul Korea Republic of Tencent HealthCare Tencent Shenzhen China Computer Vision Institute College of Computer Science and Software Engineering of Shenzhen University Shenzhen China School of Biomedical Engineering Health Science Center Shenzhen University China Xiaohe Healthcare ByteDance Guangdong Guangzhou510000 China School of Biomedical Engineering Shenzhen University China College of Computer Science & Software Engineering Shenzhen University China Department of Computer Science and Systems Engineering Universidad de La Laguna Spain Saudi Electronic University Saudi Arabia King Saud University Saudi Arabia Institute of Automation Chinese Academy of Sciences Beijing China University of Chinese Academy of Sciences Beijing China SGGS Institute of Engineering and Technology India Institute of Medical Robotics Shanghai Jiao Tong University China Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University China

With the rapid development of artificial intelligence (AI) in medical image processing, deep learning in color fundus photography (CFP) analysis is also evolving. Although there are some open-source, labeled datasets of CFPs in the ophthalmology community, large-scale datasets for screening only have labels of disease categories, and datasets with annotations of fundus structures are usually small in size. In addition, labeling standards are not uniform across datasets, and there is no clear information on the acquisition device. Here we release a multi-annotation, multi-quality, and multi-device color fundus image dataset for glaucoma analysis on an original challenge-Retinal Fundus Glaucoma Challenge 2nd Edition (REFUGE2). The REFUGE2 dataset contains 2000 color fundus images with annotations of glaucoma classification, optic disc/cup segmentation, as well as fovea localization. Meanwhile, the REFUGE2 challenge sets three sub-tasks of automatic glaucoma diagnosis and fundus structure analysis and provides an online evaluation framework. Based on the characteristics of multi-device and multi-quality data, some methods with strong generalizations are provided in the challenge to make the predictions more robust. This shows that REFUGE2 brings attention to the characteristics of real-world multi-domain data, bridging the gap between scientific research and clinical application. © 2022, CC BY-NC-ND.

关键词： Color

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