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SSRN 2024年

作者： Huang, Yan Yang, Jinzhu Sun, Qi Yuan, Yuliang Hou, Yang Shang, Jin Key Laboratory of Intelligent Computing in Medical Image Ministry of Education Northeastern University Liaoning Shenyang China School of Computer Science and Engineering Northeastern University Liaoning Shenyang China National Frontiers Science Center for Industrial Intelligence and Systems Optimization Liaoning Shenyang China Department of Radiology Shengjing Hospital of China Medical University Liaoning Shenyang China

Accurate segmentation of small vessels, such as coronary and pulmonary arteries, is crucial for early detection and treatment of vascular diseases. However, challenges persist due to the vessel's small size, complex structures, morphological variations, and limited annotated data. To address these challenges, we propose a detail-preserving network enhanced by a discriminator to improve the few-shot small vessel segmentation performance. The detail-preserving network constructs a complex module with multi-residual hybrid dilated convolution, which can enhance the network's receptive field while preserving the image's full detail features, enabling it to better capture the small vessel's structural features. Simultaneously, discriminator enhancement is incorporated into the training process through adversarial learning, effectively utilizing large amounts of unlabeled data to boost the generalization and robustness of the segmentation model. We validate the proposed method on in-house and public coronary artery datasets and public pulmonary artery datasets. Experimental results demonstrate that the proposed method significantly improves segmentation accuracy, particularly for small vessels. Compared with other state-of-the-art methods, the proposed method achieves higher accuracy, a lower false positive rate, and superior generalization capability, effectively assisting the clinical diagnosis of vessel diseases. © 2024, The Authors. All rights reserved.

关键词： Semi-supervised learning

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COph100: A comprehensive fundus image registration dataset from infants constituting the "RIDIRP" database

arXiv

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arXiv 2025年

作者： Hu, Yan Gong, Mingdao Qiu, Zhongxi Liu, Jiabao Shen, Hongli Yuan, Mingzhen Zhang, Xiaoqing Li, Heng Lu, Hai Liu, Jiang Research Institute of Trustworthy Autonomous Systems Department of Computer Science and Engineering Southern University of Science and Technology Shenzhen China Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing Ophthalmology and Visual Sciences Key Laboratory Beijing China Center for High Performance Computing and Shenzhen Key Laboratory of Intelligent Bioinformatics Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen China

Retinal image registration is vital for diagnostic therapeutic applications within the field of ophthalmology. Existing public datasets, focusing on adult retinal pathologies with high-quality images, have limited number of image pairs and neglect clinical challenges. To address this gap, we introduce COph100, a novel and challenging dataset known as the Comprehensive Ophthalmology Retinal Image Registration dataset for infants with a wide range of image quality issues constituting the public "RIDIRP" database1. COph100 consists of 100 eyes, each with 2 to 9 examination sessions, amounting to a total of 491 image pairs carefully selected from the publicly available dataset. We manually labeled the corresponding ground truth image points and provided automatic vessel segmentation masks for each image. We have assessed COph100 in terms of image quality and registration outcomes using state-of-the-art algorithms. This resource enables a robust comparison of retinal registration methodologies and aids in the analysis of disease progression in infants, thereby deepening our understanding of pediatric ophthalmic conditions. Copyright © 2025, The Authors. All rights reserved.

关键词： Image registration

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Gaussian Process-based Active Learning for Efficient Cardiovascular Disease Inference

Gaussian Process-based Active Learning for Efficient Cardiov...

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IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

作者： Stavroula C. Tassi Konstantinos D. Polyzos Dimitrios I. Fotiadis Antonis I. Sakellarios Department of Material Science and Engineering Unit of Medical Technology and Intelligent Information Systems (MEDLAB) University of Ioannina Ioannina Greece Department of Mechanical and Aeronautics Engineering University of Patras Patras Greece Department of Electrical and Computer Engineering University of Minnesota Minnesota USA Biomedical Reasearch Institute Foundation for Research and Technology-Hellas(FORTH) Ioannina Greece Department of Mechanical and Aeronautics Engineering Laboratory of Biomechanics and Biomedical Engineering University of Patras Patras Greece Unit of Medical Technology and Intelligent Information Systems (MEDLAB) University of Ioannina Ioannina Greece

Cardiovascular disease (CVD) poses a significant global health challenge, and accurate inference methods are vital for early detection and intervention. However, the quality of prediction relies heavily on the availability of labeled data, which are often limited in medical applications. To cope with the challenge of limited labeled data, we are the first to propose an active learning (AL) approach that leverages a weighted ensemble of Gaussian processes to effectively infer CVD by strategically selecting the few most informative data points to label. Through experiments conducted on the SMARTool dataset, we demonstrate the effectiveness of the advocated approach, achieving superior performance in CVD inference compared to baseline methods. Our findings highlight the potential impact of the proposed AL framework in CVD diagnosis and treatment clinical cases, particularly in scenarios where labeled data are scarce, due to data confidentiality concerns or high sampling costs.

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Design and Implementation of a Two-Limbed 3T1R Haptic Device

Design and Implementation of a Two-Limbed 3T1R Haptic Device

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IEEE/RSJ International Conference on intelligent Robots and systems (IROS)

作者： Long Kang Yang Yang Byung-Ju Yi PCA Lab Key Laboratory of Intelligent Perception and Systems for High-Dimensional Information of Ministry of Education School of Computer Science and Engineering Nanjing University of Science and Technology Nanjing China Xi'an Modern Control Technology Research Institute Xi'an China School of Automation Nanjing University of Information Science and Technology Nanjing China Department of the Electronic Systems Engineering Hanyang University Ansan South Korea

This paper presents a haptic device with a simple architecture of only two limbs that can provide translational motion in three degrees of freedom (DOF) and one-DOF rotational motion. Actuation redundancy eliminates all forward-kinematic singularities and improves the motion-force transmission property. Thanks to the special structure of the kinematic chains, all actuators are close to the base and full gravity compensation is achieved passively by using springs. Force producibility analysis shows that this haptic device is able to produce long-term continuous force feedback of 15–30 N in each direction. By developing a prototype of the haptic device and a virtual three-dimensional simulator, a preliminary performance evaluation of the haptic device was conducted. In addition, a torque distribution algorithm considering a relaxed form of actuator-torque saturation was experimentally evaluated, and a comparison with other algorithms reveals that this algorithm offers several advantages.

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How Hard is Takeover in DPoS Blockchains? Understanding the Security of Coin-based Voting Governance

arXiv

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arXiv 2023年

作者： Li, Chao Palanisamy, Balaji Xu, Runhua Duan, Li Liu, Jiqiang Wang, Wei Beijing Key Laboratory of Security and Privacy in Intelligent Transportation Beijing Jiaotong University Beijing China Department of Informatics and Networked Systems School of Computing and Information University of Pittsburgh Pittsburgh United States School of Computer Science and Engineering Beihang University Beijing China

Delegated-Proof-of-Stake (DPoS) blockchains, such as EOSIO, Steem and TRON, are governed by a committee of block producers elected via a coin-based voting system. We recently witnessed the first de facto blockchain takeover that happened between Steem and TRON. Within one hour of this incident, TRON founder took over the entire Steem committee, forcing the original Steem community to leave the blockchain that they maintained for years. This is a historical event in the evolution of blockchains and Web 3.0. Despite its significant disruptive impact, little is known about how vulnerable DPoS blockchains are in general to takeovers and the ways in which we can improve their resistance to takeovers. In this paper, we demonstrate that the resistance of a DPoS blockchain to takeovers is governed by both the theoretical design and the actual use of its underlying coin-based voting governance system. When voters actively cooperate to resist potential takeovers, our theoretical analysis reveals that the current active resistance of DPoS blockchains is far below the theoretical upper bound. However in practice, voter preferences could be significantly different. This paper presents the first large-scale empirical study of the passive takeover resistance of EOSIO, Steem and TRON. Our study identifies the diversity in voter preferences and characterizes the impact of this diversity on takeover resistance. Through both theoretical and empirical analyses, our study provides novel insights into the security of coin-based voting governance and suggests potential ways to improve the takeover resistance of any blockchain that implements this governance model. © 2023, CC BY-NC-ND.

关键词： Blockchain

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Towards silicon photonic neural networks for artificial intelligence

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science China(Information sciences) 2020年第6期63卷 105-118页

作者： Bowen BAI Haowen SHU Xingjun WANG Weiwen ZOU State Key Laboratory of Advanced Optical Communications System and Networks School of Electronics Engineering and Computer Science Peking University Frontiers Science Center for Nano-optoelectronics Peking University State Key Laboratory of Advanced Optical Communication Systems and Networks Intelligent Microwave Lightwave Integration Innovation Center(iMLic) Department of Electronic Engineering Shanghai Jiao Tong University

Brain-inspired photonic neural networks for artificial intelligence have attracted renewed interest. For many computational tasks, such as image recognition, speech processing and deep learning, photonic neural networks have the potential to increase the computing speed and energy efficiency on the orders of magnitude compared with digital electronics. Silicon Photonics, which combines the advantages of electronics and photonics, brings hope for the large-scale photonic neural network integration. This paper walks through the basic concept of artificial neural networks and focuses on the key devices which construct the silicon photonic neuromorphic systems. We review some recent important progress in silicon photonic neural networks, which include multilayer artificial neural networks and brain-like neuromorphic systems, for artificial intelligence. A prototype of silicon photonic artificial intelligence processor for ultra-fast neural network computing is also proposed. We hope this paper gives a detailed overview and a deeper understanding of this emerging field.

关键词： photonic neural networks artificial intelligence deep learning photonic computing accelerator silicon photonics

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PhenoProfiler: Advancing Phenotypic Learning for Image-based Drug Discovery

arXiv

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arXiv 2025年

作者： Li, Bo Zhang, Bob Zhang, Chengyang Zhou, Minghao Huang, Weiliang Wang, Shihang Wang, Qing Li, Mengran Zhang, Yong Song, Qianqian PAMI Research Group Department of Computer and Information Science University of Macau Taipa China Beijing Key Laboratory of Multimedia and Intelligent Software Technology Beijing Institute of Artificial Intelligence Beijing University of Technology Beijing China Department of Health Outcomes and Biomedical Informatics College of Medicine University of Florida Florida United States Faculty of Applied Sciences Macao Polytechnic University Taipa China School of Intelligent Systems Engineering Sun Yat-sen University Guangdong China Department of Cancer Biology Wake Forest School of Medicine Winston SalemNC United States

In the field of image-based drug discovery, capturing the phenotypic response of cells to various drug treatments and perturbations is a crucial step. This process involves transforming high-throughput cellular images into quantitative representations for downstream analysis. However, existing methods require computationally extensive and complex multi-step procedures, which can introduce inefficiencies, limit generalizability, and increase potential errors. To address these challenges, we present PhenoProfiler, an innovative model designed to efficiently and effectively extract morphological representations, enabling the elucidation of phenotypic changes induced by treatments. PhenoProfiler is designed as an end-to-end tool that processes whole-slide multi-channel images directly into low-dimensional quantitative representations, eliminating the extensive computational steps required by existing methods. It also includes a multi-objective learning module to enhance robustness, accuracy, and generalization in morphological representation learning. PhenoProfiler is rigorously evaluated on large-scale publicly available datasets, including over 230,000 whole-slide multi-channel images in end-to-end scenarios and more than 8.42 million single-cell images in non-end-to-end settings. Across these benchmarks, PhenoProfiler consistently outperforms state-of-the-art methods by up to 20%, demonstrating substantial improvements in both accuracy and robustness. Furthermore, PhenoProfiler uses a tailored phenotype correction strategy to emphasize relative phenotypic changes under treatments, facilitating the detection of biologically meaningful signals. UMAP visualizations of treatment profiles demonstrate PhenoProfiler’s ability to effectively cluster treatments with similar biological annotations, thereby enhancing interpretability. These findings establish PhenoProfiler as a scalable, generalizable, and robust tool for phenotypic learning, offering transformative advancement

关键词： Benchmarking

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arXiv

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arXiv 2024年

作者： Ren, Yingying Li, Qiuli Guo, Yangyang Pedrycz, Witold Xing, Lining Liu, Anfeng Song, Yanjie School of Computer Electronics and Information Guangxi University Nanning China Guangxi Key Laboratory of Multimedia Communications and Network Technology China Key Laboratory of Parallel Distributed and Intelligent Computing Guangxi University China School of Systems Science Beijing Jiaotong University Beijing China Department of Electrical and Computer Engineering University of Alberta Edmonton Canada Systems Research Institute Polish Academy of Sciences Poland Faculty of Engineering and Natural Sciences Department of Computer Engineering Sariyer Istanbul Turkey School of Electronic Engineering Xidian University Xian China School of Electronic Engineering Central South University Changsha China National Engineering Research Center of Maritime Navigation System Dalian Maritime University Dalian China

With the rapid development of the satellite industry, the information transmission network based on communication satellites has gradually become a major and important part of the future satellite ground integration network. However, the low transmission efficiency of the satellite data relay back mission has become a problem that is currently constraining the construction of the system and needs to be solved urgently. Effectively planning the task of satellite ground networking by reasonably scheduling resources is crucial for the efficient transmission of task data. In this paper, we hope to provide a task execution scheme that maximizes the profit of the networking task for satellite ground network planning considering feeding mode (SGNPFM). To solve the SGNPFM problem, a mixed-integer planning model with the objective of maximizing the gain of the link-building task is constructed, which considers various constraints of the satellite in the feed-switching mode. Based on the problem characteristics, we propose a distance similarity-based genetic optimization algorithm (DSGA), which considers the state characteristics between the tasks and introduces a weighted Euclidean distance method to determine the similarity between the tasks. To obtain more high-quality solutions, different similarity evaluation methods are designed to assist the algorithm in intelligently screening individuals. The DSGAalso uses an adaptive crossover strategy based on similarity mechanism, which guides the algorithm to achieve efficient population search. In addition, a task scheduling algorithm considering the feed-switching mode is designed for decoding the algorithm to generate a highquality scheme. The results of simulation experiments show that the DSGA can effectively solve the SGNPFM problem. Compared to other algorithms, the proposed algorithm not only obtains higher quality planning schemes but also has faster algorithm convergence speed. The proposed algorithm improves data trans

关键词： Profitability

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Complementary Information Mutual Learning for Multimodality Medical Image Segmentation

arXiv

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arXiv 2024年

作者： Shen, Chuyun Li, Wenhao Chen, Haoqing Wang, Xiaoling Zhu, Fengping Li, Yuxin Wang, Xiangfeng Jin, Bo School of Computer Science and Technology East China Normal University Shanghai200062 China School of Data Science The Chinese University of Hong Kong Shenzhen Shenzhen Institute of Artificial Intelligence and Robotics for Society Shenzhen518172 China Huashan Hospital Fudan University Shanghai200040 China School of Computer Science and Technology East China Normal University Shanghai AI Laboratory Shanghai200062 China School of Software Engineering Shanghai Research Institute for Intelligent Autonomous Systems Tongji University Shanghai200092 China

Radiologists must utilize medical images of multiple modalities for tumor segmentation and diagnosis due to the limitations of medical imaging technology and the diversity of tumor signals. This has led to the development of multimodal learning in medical image segmentation. However, the redundancy among modalities creates challenges for existing subtraction-based joint learning methods, such as misjudging the importance of modalities, ignoring specific modal information, and increasing cognitive load. These thorny issues ultimately decrease segmentation accuracy and increase the risk of overfitting. This paper presents the complementary information mutual learning (CIML) framework, which can mathematically model and address the negative impact of inter-modal redundant information. CIML adopts the idea of addition and removes inter-modal redundant information through inductive bias-driven task decomposition and message passing-based redundancy filtering. CIML first decomposes the multimodal segmentation task into multiple subtasks based on expert prior knowledge, minimizing the information dependence between modalities. Furthermore, CIML introduces a scheme in which each modality can extract information from other modalities additively through message passing. To achieve non-redundancy of extracted information, the redundant filtering is transformed into complementary information learning inspired by the variational information bottleneck. The complementary information learning procedure can be efficiently solved by variational inference and cross-modal spatial attention. Numerical results from the verification task and standard benchmarks indicate that CIML efficiently removes redundant information between modalities, outperforming SOTA methods regarding validation accuracy and segmentation effect. To emphasize, message-passing-based redundancy filtering allows neural network visualization techniques to visualize the knowledge relationship among different modalitie

关键词： Redundancy

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SuperVessel: Segmenting High-resolution Vessel from Low-resolution Retinal Image

arXiv

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arXiv 2022年

作者： Hu, Yan Qiu, Zhongxi Zeng, Dan Jiang, Li Lin, Chen Liu, Jiang Research Institute of Trustworthy Autonomous Systems Department of Computer Science and Technology Southern University of Science and Technology Shenzhen518055 China China Guangdong Provincial Key Laboratory of Brain-inspired Intelligent Computation Department of Computer Science and Engineering Southern University of Science and Technology Shenzhen518055 China

Vascular segmentation extracts blood vessels from images and serves as the basis for diagnosing various diseases, like ophthalmic diseases. Ophthalmologists often require high-resolution segmentation results for analysis, which leads to super-computational load by most existing methods. If based on low-resolution input, they easily ignore tiny vessels or cause discontinuity of segmented vessels. To solve these problems, the paper proposes an algorithm named SuperVessel, which gives out high-resolution and accurate vessel segmentation using low-resolution images as input. We first take super-resolution as our auxiliary branch to provide potential high-resolution detail features, which can be deleted in the test phase. Secondly, we propose two modules to enhance the features of the interested segmentation region, including an upsampling with feature decomposition (UFD) module and a feature interaction module (FIM) with a constraining loss to focus on the interested features. Extensive experiments on three publicly available datasets demonstrate that our proposed SuperVessel can segment more tiny vessels with higher segmentation accuracy IoU over 6%, compared with other state-of-the-art algorithms. Besides, the stability of SuperVessel is also stronger than other algorithms. We will release the code after the paper is published. Copyright © 2022, The Authors. All rights reserved.

关键词： Blood vessels

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