检索结果-内蒙古大学图书馆

Exploring the mechanistic role of epidermal growth factor receptor activation in non-cancer kidney disease

BIOCELL 2025年第1期49卷 79-92页

作者： JU-YEON LEE DAEUN MOON JINU KIM Medical Course College of MedicineCatholic Kwandong UniversityGangneung25601Republic of Kore Department of Anatomy College of MedicineJeju National UniversityJeju63243Republic of Korea Interdisciplinary Graduate Program in Advanced Convergence Technology&Science Jeju National UniversityJeju63243Republic of Korea

The epidermal growth factor receptor(EGFR)is a transmembrane glycoprotein that plays a crucial role in signal transduction and cellular *** review explores the function of EGFR in kidney physiology and its implications for various kidney *** signaling is essential for kidney function and repair mechanisms,and its dysregulation significantly impacts both acute and chronic kidney *** review discusses the normal distribution of EGFR in kidney tubular segments,the mechanism of its activation and inhibition,and the therapeutic potential of EGFR-targeting antagonists and ***,it explores the pathophysiological characteristics observed in rodent models of kidney diseases through pharmacological and genetic inhibition of EGFR,highlighting therapeutic challenges and limitations such as species differences,variability in disease models,and potential adverse ***,the findings underscore the multifaceted role of EGFR in kidney diseases,influencing inflammation,fibrosis,and tissue *** complex involvement suggests that targeting EGFR may be a beneficial therapeutic strategy for managing these conditions,potentially mitigating inflammation and fibrosis while promoting tissue repair.

关键词： Epidermal growth factor receptor Chronic kidney disease Acute kidney injury Tubulointerstitial fibrosis

来源：评论

学校读者我要写书评

暂无评论

MERNet: Multimodal Emotion Recognition in Conversation Network via Cross-Modal Knowledge Distillation and Contrastive Learning

MERNet: Multimodal Emotion Recognition in Conversation Netwo...

引用

International Conference on Big Data and Smart Computing (BIGCOMP)

作者： Sooyeon Hwang Gahgene Gweon Eunseong Kwon Interdisciplinary Program in Artificial Intelligence Seoul National University South Korea Graduate School of Convergence Science and Technology Seoul National University South Korea Dept. of Computer Science and Engineering POSTECH South Korea

ISBN: (数字)9798331529024

ISBN: (纸本)9798331529031

Multimodal Emotion Recognition in Conversation (ERC) is a task of predicting the emotion of each utterance in a conversation by utilizing both verbal and non-verbal modalities. However, existing approaches often struggle to bridge cross-modal gaps, resulting in misaligned features and frequent misclassification of minority emotions into semantically similar majority emotions. To address these challenges, we propose MERNet, a framework that employs cross-modal knowledge distillation and contrastive learning to align multimodal features and effectively distinguish subtle emotions in conversations. Our framework consists of two stages: 1) guiding non-verbal modalities with the text modality to transfer knowledge and align their features, and 2) applying contrastive learning with emotion labels as anchors to distinguish subtle differences between similar emotions and address the class imbalance problem. Experiments conducted on two benchmark datasets, IEMOCAP and MELD, demonstrate that our MERNet outperforms existing state-of-the-art models.

关键词： Knowledge engineering Bridges Emotion recognition Visualization Computational modeling Contrastive learning Benchmark testing Linguistics Big Data

来源：评论

学校读者我要写书评

暂无评论

Examining the Impact of Expression Fragmentation and Number Redundancy on Financial QA task

Examining the Impact of Expression Fragmentation and Number ...

引用

International Conference on Big Data and Smart Computing (BIGCOMP)

作者： Yoonjae Lee Kyung Seo Ki Gahgene Gweon Bugeun Kim Graduate School of Convergence Science and Technology Seoul National University South Korea Interdisciplinary Program in Artificial Intelligence Seoul National University South Korea Department of AI Chung-Ang University South Korea

ISBN: (数字)9798331529024

ISBN: (纸本)9798331529031

The goal of financial QA is to generate solution equations by solving problems about financial reports. Current financial QA models can suffer from two issues: expression fragmentation and number redundancy. We conduct experiments to examine the impact of the two issues. The experimental results show that addressing the expression fragmentation issue in financial QA using EPT improves the execution accuracy by 0.09, and alleviating the number redundancy issue by removing redundant numbers in the input of the FinQANet generator improves the execution accuracy by 0.07.

关键词： Accuracy Computational modeling Redundancy Big Data Mathematical models Generators

来源：评论

学校读者我要写书评

暂无评论

EXCESSIVE SUCROSE EXACERBATES HIGH FAT DIET-INDUCED HEPATIC INFLAMMATION AND FIBROSIS PROMOTING OSTEOARTHRITIS IN MICE MODEL

引用

Osteoarthritis and Cartilage 2025年 33卷 S139-S140页

作者： Yunhui Min Yunji Heo Dinesh Suminda Godagama Gamaarachchige minhye Kim myeongyeon shin Md. M. Ansari Young-Ok Son Interdisciplinary Graduate Program in Advanced Convergence Technology and Science Jeju National University Jeju Korea (the Republic of) Department of Animal Biotechnology Faculty of Biotechnology College of Applied Life Sciences Jeju National University Jeju-si Jeju-do Korea (the Republic of) Interdisciplinary Graduate Program in Advanced Convergence Technology and Science Jeju national University Jeju-si Jeju-do Korea (the Republic of)

来源：评论

学校读者我要写书评

暂无评论

XERICO as a target for engineering stress-resilient crops: Mechanisms, applications, and future directions

引用

Plant Physiology and Biochemistry 2025年 225卷 110013页

作者： Im, Jong Hee Kim, Won-Chan Han, Kyung-Hwan Ko, Jae-Heung Department of Horticulture Michigan State University East Lansing 48824 MI United States Interdisciplinary Graduate Program in Advanced Convergence Technology and Science Jeju National University Jeju 63243 South Korea DOE Great Lakes Bioenergy Research Center Michigan State University East Lansing 48824 MI United States School of Applied Biosciences Kyungpook National University Daegu 41566 South Korea Department of Forestry Michigan State University East Lansing 48824 MI United States of Green-Bio Science Kyung Hee University Yongin 17104 South Korea

XERICO's capacity to enhance ABA-driven stress responses across diverse crops, its regulatory crosstalk with other hormonal pathways, and its compatibility with advanced genetic engineering tools highlight its central role in sustainable agriculture. Leveraging XERICO in crop improvement programs aligns with the urgent need to mitigate the impacts of climate-induced stress in agriculture, offering a pathway toward resilient and high-yielding crops. By enabling crops to withstand drought and other environmental stresses, XERICO-based biotechnological approaches hold transformative potential for global food security and environmental sustainability. © 2025 Elsevier Masson SAS

关键词： ABA regulation Climate resilience Drought tolerance Environmental stress Genetic engineering Sustainable agriculture XERICO

来源：评论

学校读者我要写书评

暂无评论

Environmental Chromium Exposure Drives Osteoarthritis Pathogenesis via NF-κB–Hif-2α/Zip8 Signaling in Articular Cartilage

引用

Osteoarthritis and Cartilage 2025年 33卷 S376-S377页

作者： Dinesh Suminda Godagama Gamaarachchige Yunhui Min Yunji Heo minhye Kim myeongyeon shin Md. M. Ansari Young-Ok Son Interdisciplinary Graduate Program in Advanced Convergence Technology and Science Jeju National University Jeju Korea(the Republic of) Animal biothchnology jeju national university Jeju-si Korea(the Republic of) Next Generation Convergence Science and Technology Cooperative Course Jeju National University Jeju Korea (the Democratic People's Republic of) Department of Animal Biotechnology Jeju National University Jeju Jeju self-governing Province Korea (the Republic of)

来源：评论

学校读者我要写书评

暂无评论

Diel and seasonal activity pattern of alien sika deer with sympatric mammalian species from Muljangori-oreum wetland of Hallasan National Park, South Korean

引用

Journal of Ecology and Environment 2021年第1期45卷 88-96页

作者： Banjade, Maniram Han, Sang-Hyun Jeong, Young-Hun Oh, Hong-Shik Faculty of Science Education Jeju National University Jeju 63243 South Korea Korean National Park Institute of Biodiversity Conservation Korean National Park Service Gurye 57616 South Korea Interdisciplinary Graduate Programme in Advance Convergence Technology and Science Faculty of Science Education Jeju National University Jeju 63243 South Korea

Background: Sika deer, Cervus nippon, were originally introduced to South Korea from Japan and Taiwan for commercial farming purposes. Unfortunately, they were released into the wild during religious events and have since begun to impact the native ecosystem and species endemic to South Korea. The study of activity patterns can improve our understanding of the environmental impact of non-native species and their association with sympatric species. Using camera traps, we studied the diel and seasonal activity patterns of non-native sika deer and quantified the temporal overlap with sympatric mammalian species in the Muljangori-oreum wetlands of Hallasan National Park, South Korea. Results: A total of 970 trap events were recorded for five mammalian species from nine locations during the camera-trap survey. Siberian roe deer (Capreoluspygargus tianschanicus) had the highest number of recorded events (72.0%), followed by sika deer (Cervus nippon) (16.2%), wild boar (Sus scrofa) (5.0%), Asian badger (Meles leucurus) (4.5%), and the Jeju weasel (Mustela sibirica quelpartis) (2.0%). Sika deer had bimodal activity patterns throughout the year, with peaks throughout the spring-autumn twilight, and day and night time throughout the winter. Relating the daily activity of sika deer with other mammalian species, roe deer expressed the highest degree of overlap (∆₄ = 0.80) while the Asian badger demonstrated the lowest overlap (∆₄ = 0.37). Conclusions: Our data show that sika deer are a crepuscular species with seasonal variations in daily activity patterns. Additionally, we identified the temporal differences in activity peaks between different mammals in the Muljangori-oreum wetlands and found higher degree of overlap between sika deer and roe deer during twilight hours. © 2021, The Author(s).

关键词： Camera traps Diel activity Management Sika deer Sympatric species

来源：评论

学校读者我要写书评

暂无评论

Dynamics of one-dimensional spin models via complex-time evolution of tensor networks

arXiv

引用

arXiv 2025年

作者： Cha, Jeong Hyeok Lee, Hyun-Yong Kim, Heung-Sik Department of Semiconductor Physics Kangwon National University Chuncheon24341 Korea Republic of Interdisciplinary Program in Earth Environmental System Science and Engineering Kangwon National University Chuncheon24341 Korea Republic of Division of Semiconductor Physics Korea University Sejong30019 Korea Republic of Department of Applied Physics Graduate School Korea University Sejong30019 Korea Republic of Institute of Quantum Convergence Technology Kangwon National University Chuncheon24341 Korea Republic of

Studying the real-time dynamics of strongly correlated systems poses significant challenges, which have recently become more manageable thanks to advances in density matrix renormalization group (DMRG) and tensor network methods. A notable development in this area is the introduction of a complex-time evolution scheme for tensor network states, originally suggested for solving Anderson impurity model and designed to suppress the growth of entanglement under time evolution. In this study, we employ the complex-time evolution scheme to investigate the dynamics of one-dimensional spin systems, specifically the transverse-field Ising model (TFIM) and the XXZ model. Our analysis revisits the dynamic critical exponent z of the TFIM and explores the dynamical structure factor in both gapped and gapless states of the XXZ model. Importantly, the complex-time evolution reproduces the results of real-time evolution while mitigating the rapid growth of quantum entanglement typically associated with the latter. These results demonstrate that the combination of complex-time evolution and extrapolation provides a robust and efficient framework for studying the dynamics of complex quantum systems, enabling more comprehensive insights into their behavior. © 2025, CC BY.

关键词： Quantum entanglement

来源：评论

学校读者我要写书评

暂无评论

First report on the reproduction of captive Chinese many-toothed snake (Sibynophis chinensis) in Jeju Island, South Korea

引用

Journal of Ecology and Environment 2020年第1期44卷 1页

作者： Banjade, Maniram Jeong, Young-Hun Han, Sang-Hyun Kim, Yoo-Kyung Kim, Byung Soo Oh, Hong-Shik Faculty of Science Education Jeju National University Jeju 6324 South Korea Korean National Park Institute of Biodiversity Conservation Korean National Park Service Wonju South Korea Shinseong Girls Middle School Jeju City Jeju Island South Korea Interdisciplinary Graduate Programme in Advance Convergence Technology and Science Faculty of Science Education Jeju National University Jeju 6324 South Korea

The Chinese many-toothed snake (Sibynophis chinensis) is an endangered species in South Korea. To determine its reproductive activity, here we captured a gravid S. chinensis from Mulyeongari Oreum Wetland Conservation Area, Jeju Island, on May 27, 2018, and reared it at Animal Taxonomy and Morphology Laboratory, Jeju National University, South Korea. The snake oviposited a clutch of six eggs between June 12 and 20, 2018, with an average size of 24.86 ± 1.36 mm in length and 9.86 ± 0.49 mm in width, which were artificially incubated at a constant temperature of 27 °C. After incubating for 34-41 days, five of these six eggs successfully hatched. Average snout-vent length (SVL), tail length (TL), and body weight (BW) of hatchlings were 136.5 ± 5.17 mm, 47.76 ± 2.80 mm, and 1.66 ± 0.12 g, respectively. This study observed the reproductive activity of S. chinensis and characterized its eggs and hatchlings for the first time, providing valuable information for the long-term conservation plan of S. chinensis in South Korea. © 2020 The Author(s).

关键词： Clutch size Egg characteristics Egg-laying Hatchling Sibynophis chinensis

来源：评论

学校读者我要写书评

暂无评论

Surface engineering of ZnO electrocatalyst by N doping towards electrochemical CO_(2) reduction

引用

Journal of Energy Chemistry 2024年第1期88卷 71-81,I0002页

作者： Rohini Subhash Kanase Getasew Mulualem Zewdie Maheswari Arunachalam Jyoti Badiger Suzan Abdelfattah Sayed Kwang-Soon Ahn Jun-Seok Ha Uk Sim Hyeyoung Shin Soon Hyung Kang Department of Interdisciplinary Program for Photonic Engineering Chonnam National UniversityGwangju 61186Republic of Korea Graduate School of Energy Science and Technology(GEST) Chungnam National University99 Daehak-roYuseong-guDaejeon 34134Republic of Korea Department of Chemistry Education and Optoelectronic Convergence Research Center Chonnam National UniversityGwangju 61186Republic of Korea Department of Advanced Chemicals and Engineering Chonnam National UniversityGwangju 61186Republic of Korea School of Chemical Engineering Yeungnam UniversityGyeongsan 38541Republic of Korea Department of Energy Engineering Korea Institute of Energy Technology(KENTECH)Naju 58217Republic of Korea

The discovery of efficient,selective,and stable electrocatalysts can be a key point to produce the largescale chemical fuels via electrochemical CO_(2) reduction(ECR).In this study,an earth-abundant and nontoxic ZnO-based electrocatalyst was developed for use in gas-diffusion electrodes(GDE),and the effect of nitrogen(N)doping on the ECR activity of ZnO electrocatalysts was ***,a ZnO nanosheet was prepared via the hydrothermal method,and nitridation was performed at different times to control the N-doping *** an increase in the N-doping content,the morphological properties of the nanosheet changed significantly,namely,the 2D nanosheets transformed into irregularly shaped ***,the ECR performance of Zn O electrocatalysts with different N-doping content was assessed in 1.0 M KHCO_(3) electrolyte using a gas-diffusion electrode-based ECR *** the ECR activity increased after a small amount of N doping,it decreased for higher N doping *** them,the N:ZnO-1 h electrocatalysts showed the best CO selectivity,with a faradaic efficiency(FE_(CO))of 92.7%at-0.73 V *** hydrogen electrode(RHE),which was greater than that of an undoped Zn O electrocatalyst(FE_(CO)of 63.4%at-0.78 V_(RHE)).Also,the N:ZnO-1 h electrocatalyst exhibited outstanding durability for 16 h,with a partial current density of-92.1 mA cm^(-2).This improvement of N:ZnO-1 h electrocatalyst can be explained by density functional theory calculations,demonstrating that this improvement of N:ZnO-1 h electrocatalyst comes from(ⅰ)the optimized active sites lowering the free energy barrier for the rate-determining step(RDS),and(ⅱ)the modification of electronic structure enhancing the electron transfer rate by N doping.

关键词： ZnO N-doped ZnO Gas-diffusion electrode CO Selectivity Electrochemical CO_(2)reduction

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：