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SSRN 2024年

作者： Sousa, Claudevan A. Melo, Antonio F.A.A. Silva, Nefe J.B. Silva, Tânia Patrícia Silva E. Viana, Bartolomeu C. Santos, Francisco Eroni P. Garcia, Hans Department of Physics UFPI - Universidade Federal do Piauí PI Teresina64049-550 Brazil Materials Engineering Graduate Program Federal Institute of Education Science and Technology of Piauí Central Campus PI Teresina64000-040 Brazil Interdisciplinary Laboratory for Advanced Materials BioMatLab group Materials Science & Engineering Graduate Program UFPI - Universidade Federal do Piauí PI Teresina64049-550 Brazil

In this work, we reported experimental investigations on third-order optical properties of aqueous colloidal dispersions of silver nanocubes (Ag-NCs) and Ag-Au hollow nanostructures. The hollow bimetallic are nanoboxes, that were synthesized by galvanic substitution using silver nanocubes as templates, inserting silver with gold in molar ratios of 1.5 and 3.0 mL. This process adjusted tuning the Surface Plasmon Resonance (SPR) compared to the original Ag-NCs nanocubes. Femtosecond Z-scan measurements performed at 1040 nm, 350fs and laser intensities from 99.7 - 279 GW/cm2 shows negative nonlinear refraction for both nanocube and nanoboxes colloids, attributed to hot electron generation. Solvent effects are simultaneously suppressed of the nanostructures. On the other hand, the non-linear absorption observed for bimetallic nanoboxes shows the presence of saturated absorption (SA), but the Ag-NCs do not show a non-linear absorption signal. Therefore, our experimental results provide a reliable reference for the application of these bimetallic nanostructures as active media in nonlinear photonic devices. © 2024, The Authors. All rights reserved.

关键词： Surface plasmon resonance

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Single-cell protein-DNA interactomics and multiomics tools for deciphering genome regulation

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National science Open 2023年第3期2卷 64-82页

作者： Haiqing Xiong Runyu Wang Aibin He State Key Laboratory of Experimental Hematology National Clinical Research Center for Blood DiseasesHaihe Laboratory of Cell EcosystemInstitute of Hematology&Blood Diseases HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeTianjin 300020China Peking University-Tsinghua University-National Institute of Biological Science Joint Graduate Program Academy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China Institute of Molecular Medicine College of Future TechnologyPeking-Tsinghua Center for Life SciencesPeking UniversityBeijing 100871China

The emergence of single-cell genomic and transcriptomic sequencing accelerates the development of single-cell epigenomic technologies,providing an unprecedented opportunity for decoding cell fate decisions largely encoded in the *** advances in single-cell multimodality epigenomic technologies facilitate directly interrogating the reg-ulatory relationship between multi-layer molecular information in the same *** this review,we discuss recent progress in development of single-cell multimodality epigenomic technologies and applications in elucidating cellular diversifications in development and diseases,with a focus on protein-DNA interactomics and regulatory links between epigenome and ***,we provide perspective on the future direction of single-cell multiomics tool development as well as challenges facing ahead.

关键词： single-cell protein-DNA interaction single-cell multiomics single-cell epigenomics epigenome genome regulation

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Wireless,multimodal sensors for continuous measurement of pressure,temperature,and hydration of patients in wheelchair

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npj Flexible Electronics 2023年第1期7卷 479-493页

作者： Seokjoo Cho Hyeonseok Han Hyunwoo Park Sung-Uk Lee Jae-Hwan Kim Sung Woo Jeon Mengqiu Wang Raudel Avila Zhaoqian Xi Kabseok Ko Minsu Park Jungyup Lee Myungwoo Choi Je-Sang Lee Weon Gi Min Byeong-Ju Lee Soyeong Lee Jungrak Choi Jimin Gu Jaeho Park Min Seong Kim Junseong Ahn Osman Gul Chankyu Han Gihun Lee Seunghwan Kim Kyuyoung Kim Jeonghyun Kim Chang-Mo Kang Jahyun Koo Sung Soo Kwak Sungbong Kim Dong Yun Choi Seokwoo Jeon Hyung Jin Sung Yong Bae Park Minkyu Je Young Tae Cho Yong Suk Oh Inkyu Park Department of Mechanical Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea School of Electrical Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Advanced 3D Printing Technology Development Division Korea Atomic Energy Research InstituteDaejeon 34057Republic of Korea Department of Electrical and Computer Engineering University of Illinois at Urbana-ChampaignUrbanaIL 61801USA State Key Laboratory of Structural Analysis for Industrial Equipment Department of Engineering MechanicsDalian University of TechnologyDalian 116023P.R.China Department of Mechanical Engineering Northwestern UniversityEvanstonIL 60208USA DUT-BSU Joint Institute Dalian University of TechnologyDalian 116023China Ningbo Institute of Dalian University of Technology Ningbo 315016China Department of Electronics Engineering Kangwon National UniversityChuncheon 24341Republic of Korea Querrey-Simpson Institute for Bioelectronics Northwestern UniversityEvanstonIL 60208USA Sibel Health Inc NilesIL 60714USA Department of Materials Science and Engineering KAIST Institute for The Nanocentury(KINC)Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Department of Rehabilitation Medicine Gimhae Hansol Rehabilitation&Convalescent HospitalGimhae 50924Republic of Korea Department of planning and development Gimhae Hansol Rehabilitation&Convalescent HospitalGimhae 50924Republic of Korea Department of rehabilitation medicine Pusan national university hospitalBusan 49241Republic of Korea Department of AI Convergence Network Ajou UniversitySuwon 16499Republic of Korea Department of Electronic Convergence Engineering Kwangwoon UniversitySeoul 01897Republic of Korea Korea Photonics Technology Institute Gwangju 61007Republic of Korea School of Biomedical Engineering Korea UniversitySeoul 02841Republic of Korea Interdisciplinary Program in Precision Public Health Korea UniversitySeoul 02841Republic of Korea Center

Individuals who are unable to walk independently spend most of the day in a *** population is at high risk for developing pressure injuries caused by ***,early diagnosis and prevention of these injuries still remain ***,we introduce battery-free,wireless,multimodal sensors and a movable system for continuous measurement of pressure,temperature,and hydration at skin *** device design includes a crack-activated pressure sensor with nanoscale encapsulations for enhanced sensitivity,a temperature sensor for measuring skin temperature,and a galvanic skin response sensor for measuring skin hydration *** movable system enables power harvesting,and data communication to multiple wireless devices mounted at skin-cushion interfaces of wheelchair users over full body *** evaluations and numerical simulations of the devices,together with clinical trials for wheelchair patients,demonstrate the feasibility and stability of the sensor system for preventing pressure injuries caused by sitting.

关键词： injuries modal mounted

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Microstructure and Thermal Conductivity of Porous Al2 O3-ZrO2 Ceramics 58th

Microstructure and Thermal Conductivity of Porous Al2 O3-ZrO...

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58th Brazilian Ceramic Conference, CBC 2014

作者： Delbrücke, Tiago Gouvêa, Rogério A. Raubach, Cristiane W. Longo, Elson Sousa, Vânia C. M.tebcheranic, Sergio Kubaski, Evaldo T. Moreira, Mário L. Jurado, Jose R. Cava, Sergio Graduate Program in Science and Materials Engineering Technology Development Center Federal University of Pelotas RS Pelotas96010-900 Brazil Laboratory of Biomaterials & Advanced Ceramics Federal University of Rio Grande do Sul RS Porto Alegre91509-900 Brazil Interdisciplinary Laboratory of Ceramic Materials Ponta Grossa State University PR Ponta Grossa84030-900 Brazil National Institute of Science and Technology of Materials in Nanotechnology Paulista State University SP Araraquara14801-907 Brazil Glass Department Institute of Glass and Ceramic Madrid28049 Spain Institute of Physics and Mathematics Federal University of Pelotas RS Pelotas96010-900 Brazil

The improvement on the development of porous ceramic materials has leaded to new technologies in thermal insulation, for example, composite materials for better performance of pressure vessels in rocket engines. Within this context, the present work aims to evaluate the ability of a refractory ceramic base alumina/zirconia through the processes of co-precipitation and replica method in an organic fiber template. The green body was burnt-out and sintered at 1200-1600°C to obtain the continuous porous ceramic fibers. In the FEG-SEM analysis, an interconnected porous structure with small grains was observed. The crystalline phases were determined by X-ray diffraction and compared to micro-Raman results regarding the crystalline structure confirms that there present in the material zirconia is composed of more than one phase. Porosity was calculated through a mercury porosimeter as 77.9%, and the Laser Flash method gave a thermal conductivity value of 1.61 K W.m−1 .K−1 for the Al2 O3-ZrO2 fibers. © 2015 Trans Tech Publications Ltd, Switzerland.

关键词： Porosity

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Multivalent‐Interaction‐Driven Assembly of Discrete, Flexible, and Asymmetric Supramolecular Protein Nano‐Prisms

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Angewandte Chemie 2020年第51期132卷 23444-23451页

作者： Suyeong Han Dr. Yu‐na Kim Gyunghee Jo Dr. Young Eun Kim Prof. Dr. Ho Min Kim Dr. Jeong‐Mo Choi Prof. Dr. Yongwon Jung Department of Chemistry Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Korea These authors contributed equally to this work. Biomedical Science and Engineering Interdisciplinary Program KAIST Daejeon 34141 Korea Graduate School of Medical Science & Engineering KAIST Daejeon 34141 Korea Center for Biomolecular & Cellular Structure Institute for Basic Science (IBS) Daejeon 34126 Korea Natural Science Research Institute KAIST Daejeon 34141 Korea Department of Chemistry Busan National University Busan 46241 Korea

Multivalent interactions between protein‐oligomer‐fused binding pairs allowed highly monodisperse assembly of two protein oligomers, where spacing between oligomers can be widely varied. Two different oligomers or three oligomers can also be discretely assembled into protein layer structures via this *** approaches to design monodisperse protein assemblies require rigid, tight, and symmetric interactions between oligomeric protein units. Herein, we introduce a new multivalent‐interaction‐driven assembly strategy that allows flexible, spaced, and asymmetric assembly between protein oligomers. We discovered that two polygonal protein oligomers (ranging from triangle to hexagon) dominantly form a discrete and stable two‐layered protein prism nanostructure via multivalent interactions between fused binding pairs. We demonstrated that protein nano‐prisms with long flexible peptide linkers (over 80 amino acids) between protein oligomer layers could be discretely formed. Oligomers with different structures could also be monodispersely assembled into two‐layered but asymmetric protein nano‐prisms. Furthermore, producing higher‐order architectures with multiple oligomer layers, for example, 3‐layered nano‐prisms or nanotubes, was also *** a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re‐organized for online delivery, but are not copy‐edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the *** note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

关键词： multivalent interaction protein assembly protein design protein engineering protein–protein interactions

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Glucocorticoid Enhances Presenilin1-Dependent Aβ Production at Er's Mitochondrial-Associated Membrane by Downregulating Rer1 in Neuronal Cells

SSRN

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SSRN 2023年

作者： Choi, Gee Euhn Park, Ji Yong Park, Mo Ran Yoon, Jee Hyeon Han, Ho Jae Laboratory of Veterinary Biochemistry College of Veterinary Medicine Veterinary Medical Research Institute Jeju National University Jeju63243 Korea Republic of Interdisciplinary Graduate Program in Advanced Convergence Technology & Science Jeju National University Jeju63243 Korea Republic of Department of Veterinary Physiology College of Veterinary Medicine Research Institute for Veterinary Science BK21 Four Future Veterinary Medicine Leading Education & Research Center Seoul National University Seoul08826 Korea Republic of

Stress-induced release of glucocorticoid is an important amyloidogenic factor that upregulates amyloid precursor protein (APP) and β secretase 1 (BACE1) levels. Glucocorticoid also contributes to the pathogenesis of Alzheimer’s disease (AD) by increasing ER-mitochondria connectivity, in which amyloid β (Aβ) processing occurs rigorously because of its lipid raft-rich characteristics. However, the mechanism by which glucocorticoid enhances γ-secretase activity in the mitochondrial-associated membrane of ER (MAM) and subsequent accumulation of mitochondrial Aβ is unclear. In this study, we determined how glucocorticoid enhances Aβ production in MAM using SH-SY5Y cells and ICR mice. First, we observed that cortisol-induced Aβ accumulation in mitochondria preceded its extracellular apposition by enhancing γ-secretase activity, which was the result of increased presenilin 1 (PSEN1) localization in MAM. Screening data revealed that cortisol selectively downregulated the ER retrieval protein Rer1, which triggered its maturation and subsequent entry into the endocytic secretory pathway of PSEN1. Accordingly, overexpression of RER1 reversed the deleterious effects of mitochondrial Aβ on mitochondrial respiratory function and neuronal cell viability. Notably, we found that cortisol guided the glucocorticoid receptor (GR) to bind directly to the RER1 promoter, thus trans-repressing its expression. Inhibiting GR function reduced Aβ accumulation at mitochondria and improved the outcome of a spatial memory task in mice exposed to corticosterone. Taken together, glucocorticoid enhances PSEN1-mediated Aβ generation at MAM by downregulating Rer1, which is a potential target at early stages of AD pathogenesis. © 2023, The Authors. All rights reserved.

关键词： Mitochondria

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Correction to: N‑doped carbon nanospheres as selective fluorescent probes for mercury detection in contaminated aqueous media: chemistry, fluorescence probing, cell line patterning, and liver tissue interaction

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Environmental science and pollution research international 2025年第20期32卷 2025 May 6页

作者： Soheil Sojdeh Ali Banitalebi Dehkordi Alireza Badiei Ali Zarrabi Pooyan Makvandi Milad Ashrafizadeh Mohammad Reza Saeb Eder C Lima Mohammad Rabiee Mohsen Asadnia Thomas J Webster Navid Rabiee School of Chemistry College of Science University of Tehran P.O. Box Tehran 14155‑6455 Iran. Department of Biomedical Engineering Faculty of Engineering and Natural Sciences Istinye University Istanbul Turkey. Centre for Materials Interfaces Istituto Italiano Di Tecnologia 56025 Pisa Italy. Sabanci University Orta Mahalle Üniversite Caddesi No. 27 Orhanlı Tuzla 34956 Istanbul Turkey. Department of Polymer Technology Gdańsk University of Technology G. Narutowicza 11/12 80‑233 Gdańsk Poland. Institute of Chemistry Federal University of Rio Grande Do Sul (UFRGS) Av. Bento Goncalves 9500 Postal Box 15003 Porto Alegre ZIP 91501‑970 Brazil. profederlima@***. Biomaterials Group Department of Biomedical Engineering Amirkabir University of Technology Tehran Iran. School of Engineering Macquarie University New South Wales Sydney 2109 Australia. School of Health Sciences and Biomedical Engineering Hebei University of Technology Tijian 300130 China. School of Engineering Saveetha University Chennai 602105 India. Interdisciplinary Laboratory for Advanced Materials (LIMAV) Materials Science and Engineering Graduate Program Federal University of Piaui Teresina 64049‑550 Brazil. Centre for Molecular Medicine and Innovative Therapeutics Murdoch University Perth 6150 Australia.

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Linear and nonlinear plasmonic effects modulated by a metalinsulator transition

Linear and nonlinear plasmonic effects modulated by a metali...

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IEEE/LEOS Winter Topical Meeting Series

作者： R. F. Haglund E. U. Donev L. C. Feldman D. W. Ferrara R. Lopez J. Y. Suh K.A. Tetz Department of Physics and Astronomy Interdisciplinary Graduate Program in Materials Science and Vanderbilt Institute for Nanoscale Science and Engineering Vanderbilt University Nashville TN USA Department of Physics and Astronomy and Department of Materials Science and Engineering Rutgers University Piscataway NJ USA Department of Physics and Astronomy and Institute for Advanced Materials Nanoscience and Technology North Carolina State University Chapel Hill NC USA

Localized and propagating plasmonic effects in noble-metal nanostructures are receiving worldwide attention as potential enabling principles for optical and electro-optic devices. A critical need in plasmonic device design is a general technique for active modulation of the plasmon response. In this paper, we describe the use of a reversible, solid-solid phase transition in VO 2 to modulate plasmonic response. Case studies are drawn from experiments on nano structured hole and particle arrays in which VO 2 acts as a modulator by altering the local dielectric constant.

关键词： Plasmons Optical devices Optical propagation Nanostructures Nonlinear optical devices Nonlinear optics Optical modulation Electrooptic devices Phase modulation Dielectric constant

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Thermal Hall Effects of Spins and Phonons in Kagome Antiferromagnet Cd-Kapellasite

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Physical Review X 2020年第4期10卷 041059-041059页

作者： Masatoshi Akazawa Masaaki Shimozawa Shunichiro Kittaka Toshiro Sakakibara Ryutaro Okuma Zenji Hiroi Hyun-Yong Lee Naoki Kawashima Jung Hoon Han Minoru Yamashita The Institute for Solid State Physics The University of Tokyo Kashiwa 277-8581 Japan Graduate School of Engineering Science Osaka University Toyonaka 560-8531 Japan Department of Physics Chuo University Kasuga Bunkyo-ku Tokyo 112-8551 Japan Okinawa Institute of Science and Technology Graduate University Kunigami-gun 904-0495 Japan Department of Applied Physics Graduate School Korea University Sejong 30019 Korea Division of Display and Semiconductor Physics Korea University Sejong 30019 Korea Interdisciplinary Program in E·ICT-Culture-Sports Convergence Korea University Sejong 30019 Korea Department of Physics Sungkyunkwan University Suwon 16419 Korea

We investigate the thermal-transport properties of the kagome antiferromagnet Cd-kapellasite (Cd-K). We find that a field-suppression effect on the longitudinal thermal conductivity κxx sets in below approximately 25 K. This field-suppression effect at 15 T becomes as large as 80% at low temperatures, suggesting a large spin contribution κxxsp in κxx. We also find clear thermal Hall signals in the spin liquid phase in all Cd-K samples. The magnitude of the thermal Hall conductivity κxy shows a significant dependence on the sample’s scattering time, as seen in the rise of the peak κxy value in almost linear fashion with the magnitude of κxx. On the other hand, the temperature dependence of κxy is similar in all Cd-K samples; κxy shows a peak at almost the same temperature of the peak of the phonon thermal conductivity κxxph which is estimated by κxx at 15 T. These results indicate the presence of a dominant phonon thermal Hall κxyph at 15 T. In addition to κxyph, we find that the field dependence of κxy at low fields turns out to be nonlinear at low temperatures, concomitantly with the appearance of the field suppression of κxx, indicating the presence of a spin thermal Hall κxysp at low fields. Remarkably, by assembling the κxx dependence of κxysp data of other kagome antiferromagnets, we find that, whereas κxysp stays a constant in the low-κxx region, κxysp starts to increase as κxx does in the high-κxx region. This κxx dependence of κxysp indicates the presence of both intrinsic and extrinsic mechanisms in the spin thermal Hall effect in kagome antiferromagnets. Furthermore, both κxyph and κxysp disappear in the antiferromagnetic ordered phase at low fields, showing that phonons alone do not exhibit the thermal Hall effect. A high field above approximately 7 T induces κxyph, concomitantly with a field-induced increase of κxx and the specific heat, suggesting a coupling of the phonons to the field-induced spin excitations as the origin of κxyph.

关键词： Frustrated magnetism Spin liquid Thermal Hall effect Thermal conductivity

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Correction: Influence of the ecological environment on the structural characteristics and bioactivities of polysaccharides from alfalfa (Medicago sativa L.)

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Food & function 2022年第14期13卷 7942-7943页

作者： Chongyu Zhang Eunyoung Kim Jiamei Cui Yunpeng Wang Yunkyoung Lee Guiguo Zhang Department of Nutrition and China-Korea Joint R&D center on Plant-derived polysaccharide Shandong Agricultural University 61 Daizong Street Taian City 271018 China. zhanggg@***. Department of Food Science and Nutrition and Korea-China Joint R&D center on Plant-derived polysaccharide Jeju National University Jeju 63243 South Korea. lyk1230@jejunu.ac.kr. Interdisciplinary Graduate Program in Advanced Convergence Technology & Science Jeju National University Jeju 63243 South Korea.

Correction for 'Influence of the ecological environment on the structural characteristics and bioactivities of polysaccharides from alfalfa ( L.)' by Chongyu Zhang , , 2022, https://***/10.1039/d2fo00371f.

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