Skin diseases in companion cats can worsen if not treated promptly, and this can increase the financial burden on pet owners. To prevent this, early and accurate diagnosis is essential. This study introduces a deep le...
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In modern society, the number of households raising pets is increasing. As pet ownership increases, the cost of treating companion cats is also rising, with a significant portion of these costs going toward the treatm...
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In contemporary society, pets are increasingly regarded as integral family members, contributing significantly to human quality of life. The growing prevalence of dog ownership has concurrently escalated the economic ...
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The epidermal growth factor receptor(EGFR)is a transmembrane glycoprotein that plays a crucial role in signal transduction and cellular *** review explores the function of EGFR in kidney physiology and its implication...
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The epidermal growth factor receptor(EGFR)is a transmembrane glycoprotein that plays a crucial role in signal transduction and cellular *** review explores the function of EGFR in kidney physiology and its implications for various kidney *** signaling is essential for kidney function and repair mechanisms,and its dysregulation significantly impacts both acute and chronic kidney *** review discusses the normal distribution of EGFR in kidney tubular segments,the mechanism of its activation and inhibition,and the therapeutic potential of EGFR-targeting antagonists and ***,it explores the pathophysiological characteristics observed in rodent models of kidney diseases through pharmacological and genetic inhibition of EGFR,highlighting therapeutic challenges and limitations such as species differences,variability in disease models,and potential adverse ***,the findings underscore the multifaceted role of EGFR in kidney diseases,influencing inflammation,fibrosis,and tissue *** complex involvement suggests that targeting EGFR may be a beneficial therapeutic strategy for managing these conditions,potentially mitigating inflammation and fibrosis while promoting tissue repair.
Computer-aided diagnosis (CADx) systems play a crucial role in accurately diagnosing and monitoring diseases through medical imaging. However, there are many challenges, such as data scarcity and complex structural pa...
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Computer-aided diagnosis (CADx) systems play a crucial role in accurately diagnosing and monitoring diseases through medical imaging. However, there are many challenges, such as data scarcity and complex structural patterns, limiting the performance of deep-learning models. Although conventional data-augmentation techniques can help mitigate these limitations, excessive augmentation may distort critical diagnostic information, leading to suboptimal performance. To address this issue, this study proposes CyclicAugment, a novel data-augmentation strategy that dynamically adjusts augmentation intensity in a cyclic manner throughout training. The method gradually transitions from using original data as weak augmentation, subsequently applying strong augmentation before reverting to weak augmentation again, reintroducing the original data. This process ensures stable training through an adaptive learning rate. By cyclically adjusting augmentation intensity, our approach enhances data diversity while preserving essential diagnostic information, thereby improving the generalizability of deep learning models. We validated CyclicAugment across six different medical imaging datasets and multiple deep learning architectures, including convolutional neural networks, vision transformers, and multilayer perceptrons. Our framework achieved a maximum accuracy improvement of 8.8%, reaching a peak performance of 0.927 and thereby demonstrating its effectiveness in enhancing medical image analysis.
Motivation: Accurately predicting drug-target protein interactions (DTI) is a cornerstone of drug discovery, enabling the identification of potential therapeutic compounds. Sequence-based prediction models, despite th...
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Background:Binge drinking(BD)has been associated with elevated liver enzymes,but the joint association of BD and adiposity with liver enzymes is *** aimed to examine the combined association of BD and obesity with ele...
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Background:Binge drinking(BD)has been associated with elevated liver enzymes,but the joint association of BD and adiposity with liver enzymes is *** aimed to examine the combined association of BD and obesity with elevated liver ***:Data were obtained from 285,600 patients in the Korean National Health check-up program during *** I BD(BD I)was defined as alcohol consumption of>60g(men)or>40g(women)on one occasion in the previous ***-intensity BD(HIBD)corresponded to at least two times the BD I *** and abdominal obesity were defined by body mass index and waist *** regression was used to examine the independent and joint associations of BD and obesity with elevated alanine aminotransferase(ALT),aspartate aminotransferase(AST),and gamma-glutamyl transferase(GGT)*** excess risk(RERI),attributable proportion(AP),and synergy index(SI)were calculated to estimate the additive interaction ***:The mean age was 42.1±0.03years and 50.2%were *** ALT[odds ratio(OR)1.09,95%confidence interval(CI)1.02-1.16],AST(OR 1.16,95%CI 1.11-1.23),and GGT(OR 1.84,95%CI 1.05-1.94)were associated with *** odds of elevated ALT(OR 3.57,95%CI 3.43-3.71),AST(OR 3.47,95%CI 3.37-3.58),and GGT(OR 2.10,95%CI 1.98-2.12)were observed in individuals with general obesity.A similar trend was observed for abdominal *** RERI,AP,and SI for the interaction effect of BD and general obesity were 23%,7%,and 13%for elevated AST levels,and 67%,24%,and 58%for elevated GGT levels,*** effects were observed for the interaction between BD and abdominal ***:Obesity aggravated the odds of elevated liver AST and GGT levels in HIBD.
To assist radiologists for the characterization of breast masses, Computer-aided Diagnosis(CADx) system has been studied. The CADx system can improve the diagnostic accuracy of radiologists by providing objective info...
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Automatic age estimation has been used in many social network applications, practical commercial applications, and human-computer interaction visual-surveillance biometrics. However, it has rarely been explored. In th...
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- Dental caries is one of the most popular oral disease. The aim of automatic dental cavity detection system is helping dentist to make accurate diagnosis. It is very important to separate cavity from the teeth in the...
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