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作者： Li, Ying Anjaneya Reddy Guntur, S.R. Choi, Min Joo Paeng, Dong-Guk Marine Industrial Engineering Cheju National University Jeju 690-756 Korea Republic of Department of Medicine Cheju National University Jeju 690-756 Korea Republic of Interdisciplinary Postgraduate Program in Biomedical Engineering Cheju National University Jeju 690-756 Korea Republic of

Tofu was suggested as Tissue Mimicking Materials (TMMs) due to its low cost, availability, gelatinous nature, and shape flexibility. However, the similarity in acoustic properties of the different packets of Tofu and acorn curd (Muk) is critical for TMMs but not fully investigated yet. In order to improve the accuracy for time-consuming and multi-stepped measurements of acoustic properties, an automated measurement system was developed. Using the automated system, the acoustic properties Tofu and Muk were measured to know whether they are similar among the different samples. In conclusion, the acoustic properties were measured to be similar among the different packets of Tofu and Muk, suggesting them as potential TMMs.

关键词： Biomaterials

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Measurements of absorption coefficients within biological tissue in vitro

Measurements of absorption coefficients within biological ti...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： Nam Jung Kim Hyun Soo Lim Interdisciplinary Program of Biomedical Engineering Major Chungnam National University South Korea Department of Biomedical Engineering College of Medicine Chungnam National University South Korea

The authors have examined the absorption coefficients of biological tissue in vitro. To develop the medical instruments for most applications, they have used as a light source the specific fixed wavelengths of lasers. So there are some restrictions while using the optical properties of biological tissue. To broaden the selection of wavelength, the authors experimented with 660/spl sim/940 nm on the highly scattering turbid medium to find out optical properties. The results shows that the absorption coefficients are different depending on wavelength and for each biological tissue.

关键词： Biological tissues In vitro Optical scattering biomedical optical imaging Optical sensors Light scattering Light sources X-ray scattering Electromagnetic wave absorption Equations

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A study on the modeling of nonlinear system using genetic programming

A study on the modeling of nonlinear system using genetic pr...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： Boyeon Kim Kwangsuk Park Interdisciplinary Program of Biomedical Engineering Major Seoul National University South Korea Department of Biomedical Engineering College of Medicine Seoul National University South Korea

Even though there are several deterministic methods for the modeling of linear systems, there is no standard method for the modeling of nonlinear systems. Most biological systems can be thought of as nonlinear systems. For the modeling of biological systems the authors have studied nonlinear systems using genetic programming. Time series were generated from the simple known nonlinear dynamics. Then nonlinear dynamics was estimated from these time series using genetic programming. For the tested nonlinear systems this suggested method estimated the nonlinear dynamics correctly. This method also has been applied for the modeling of the dynamics of the 24-hour electrocardiogram.

关键词： Nonlinear systems Genetic programming Nonlinear equations Dynamic programming Time measurement Biological system modeling Nonlinear dynamical systems Biological systems Genetic mutations Biological cells

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Resorbable polymer-ceramic composites for orthopedic scaffold applications

Resorbable polymer-ceramic composites for orthopedic scaffol...

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28th International Conference on Advanced Ceramics and Composites

作者： Vaidyanathan, R. Hecht, B. Studley, A. Phillips, T. Calvert, P.D. Tellis, B. Coleman, A. Szivek, J. Advanced Ceramics Research Inc. 3292 E. Hemisphere Loop Tucson AZ 85706 University of Arizona Arizona Material Laboratories Tucson AZ 85712 Biomedical Engineering Interdisciplinary Program University of Arizona Tucson AZ 85712

In current state-of-the-art resorbable orthopedic implant materials, loss of strength occurs before substantial mass loss in the degradation process. Materials such as 1:1 PLA:PGA copolymers become too weak to carry any load long before significant amounts of bone have grown to replace the eroded prostheses. An alternative is a two-stage implant material that is both load bearing and osteoconductive;a property of a material to encourage bone already being formed, to lie closely to or adhere to its surface. To achieve this, an interpenetrating network of osteoconductive material and strong (but degradable) biocompatible material is needed. In comparison to conventional prosthesis or scaffold manufacturing routes, rapid prototyping (RP) techniques are an attractive means of fabricating these two-stage implants. A poly butylene terephthalate polymer blend scaffold with 150-300 urn diameter interconnected pores was built using RP and coated with a thin coating of tricalcium phosphate (TCP) or hydroxy apatite suspension in a polycaprolactone matrix. Tissue culture results showed that scaffolds with such thin coatings were more conducive to growth of the cells, perhaps due to a more open scaffold, where the cells can proliferate more easily compared to the other types. The interpenetrating combination of the two biodegradable materials was designed to allow rapid bone in-growth while providing support. This preliminary study validates our hypothesis that the RP process combined with thin coating of HA can tailor an implant to the needs of a specific patient.

关键词： Composite materials

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The complete mitochondrial genome of the Argentine red shrimpPleoticus muelleri(Bate, 1888) (Crustacea, Decapoda, Solenoceridae)

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Mitochondrial DNA Part B 2018年第2期3卷 1027-1028页

作者： Nack-Keun Kim Jobaidul Alam Gyung Ryul Kim Sapto Andriyono Hyun Park Hyun-Woo Kim Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of Korea Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaFisheries and Marine Faculty Universitas Airlangga Surabaya Indonesia Korea Polar Research Institute Korea Ocean Research and Development Institute Incheon Republic of Korea Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaDepartment of Marine Biology Pukyong National University Busan Republic of Korea

The complete mitochondrial genome of Argentine red shrimp,Pleoticus muelleri(Bate, 1888) was determined using the MiSeq platform. Its mitogenome (16,189 bp) encoded the canonical 13 protein-coding genes, 22 tRNA genes, two rRNA genes. Start codons of all protein-coding genes were ATN except for ATP8, while incomplete stop codons (T–) were identified in six genes including COXI, COXII, COXIII, NAD3, NAD5, and NAD6. The mitogenome ofP. muellerishowed highest sequence identity withParapenaeopsis hardwickii(82%) andSolenocera crassicornis(81%). Phylogenetic analysis showed three shrimps in Solenoceridae includingP. muelleriwere grouped together from those in Penaeidae, which suggests taxonomic reexamination for those in those family.

关键词： Next generation sequencing Pleoticus muelleri mitochondrial genome decapod phylogeny

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Molecular characterization of the complete mitochondrial genome of morotoge shrimpPandalopsis japonica(Decapoda: Pandalidae)

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Mitochondrial DNA Part B 2019年第1期4卷 545-546页

作者： Tae-Ho Yoon Sapto Andriyono Hye-Eun Kang Nack-keun Kim Soo Rin Lee Hyun-Woo Kim Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of Korea Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaDepartment of Marine Fisheries and Marine Faculty Universitas Airlangga Surabaya East Java Indonesia Department of Marine Biology Pukyong National University Busan Republic of Korea Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaDepartment of Marine Biology Pukyong National University Busan Republic of Korea

The complete mitochondrial genome of the morotoge shrimp,Pandalopsis japonicawas determined by the high-throughput sequencing technique. The mitogenome ofP. japonica(15,909 bp) encoded the 13 protein-coding genes (PCGs), 22 tRNA genes, 2 rRNA genes as well as the non-coding control region (D-Loop). The mitochondrial genome ofP. japonicashowed an identical gene arrangement in its mitochondrial genome to its relative Pandalid shrimps includingP. borealis and P. *** 13 compared mitogenomes within order Suborder Pleocyemata,P. japonicawas most closely related toP. hypsinotuswith 86% sequence identity clustering together with three other shrimps in family Pandalidae.

关键词： High-throughput sequencing Pandalidae mitochondrial genome shrimp East/Japan Sea

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The complete mitochondrial genome of spearnose grenadier,Coelorinchus multispinulosus, Katayama, 1942 (Gadiformes: Macrouridae)

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Mitochondrial DNA Part B 2019年第1期4卷 1123-1124页

作者： Sapto Andriyono Ah-Ran Kim Md. Jobaidul Alam Hyun Park Hyun-Woo Kim Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaFisheries and Marine Faculty Universitas Airlangga Surabaya Indonesia Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of Korea Korea Polar Research Institute Korea Ocean Research and Development Institute Incheon Republic of Korea Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaDepartment of Marine Biology Pukyong National University Busan Republic of Korea

The complete mitochondrial genome ofCoelorinchus multispinulosuswas determined using the MiSeq platform. The mitogenome ofC. multispinulosus(15,937 bp) contained 13 protein-coding genes, 22 tRNAs, two ribosomal RNAs (12S and 16S), and a control region (D-Loop). The G + C content of its mitogenome was 44.69%, which was lower than A + T contents (55.31%). Unusual start codon (GTG) was identified in three protein-coding genes including COX1, ND2, and ND3. Incomplete stop codons (TA–/T–) were shown in six genes including COX1, COX2, COX3, ND3, ND4, and ATP6. Based on the phylogenetic tree with the currently reported mitogenomes in the family Macrouridae,C. multispinulosuswas most closely related toCoelorinchus kishinouyeiwith 85% nucleotide sequence identity.

关键词： Next-generation sequencing Coelorinchus multispinulosus mitochondrial genome deep-sea fish

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Photo-triggering of the membrane gates in photo-responsive polymer for drug release

Photo-triggering of the membrane gates in photo-responsive p...

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2005 27th Annual International Conference of the engineering in Medicine and Biology Society, IEEE-EMBS 2005

作者： Lee, Jae Kyoo Lee, Hoeun Jang, Eunje Lee, Sin-Doo Kim, Sung June Interdisciplinary Program of Biomedical Engineering Seoul National University Seoul Korea Republic of School of Chemical and Biomolecular Engineering Cornell University Ithaca NY School of Electrical Engineering Seoul National University Seoul Korea Republic of Nano-Bioelectronics and Systems Research Center Seoul National University Seoul Korea Republic of

ISBN: (纸本)0780387406

The use of light stimulus for triggering drug is a promising method for accurate drug delivery. A new approach using azopolymer membrane and laser holography was investigated for developing light-triggering drug delivery system. Polymeric drug delivery system was prepared by covering azopolymer membrane on a drug agent. Holographic laser interference generated surface relief grating pattern on the azopolymer surface. The widths and depths of gates on the polymer membrane were easily modified by adjusting incident angle and irradiation time. Ar laser made the polymeric membrane permeable to the drug agent and release it in a solution. This result indicated that the azopolymer and laser holography would provide a strong foundation for the light-triggering drug delivery system. © 2005 IEEE.

关键词： Biological membranes

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The complete mitochondrial genome of black-spot snapper,Lutjanus fulviflamma(Perciformes: Lutjanidae)

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Mitochondrial DNA Part B 2019年第1期4卷 366-367页

作者： Sapto Andriyono Sinar Pagi Sektiana Jobaidul Alam Hyun-Woo Kim Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaDepartment of Marine Fisheries and Marine Faculty Universitas Airlangga C Campus Jl. Mulyorejo Surabaya East Java Surabaya Indonesia Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of Korea Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaDepartment of Marine Biology Pukyong National University Busan Republic of Korea

The complete mitochondrial genome sequence of Dory snapper,Lutjanus fulviflamma,was determined by high-throughput sequencing (HTS) technique. The circular mitogenome ofL. fulviflammawas 16,512bp in length encoding 37 genes (13 proteins, 22 tRNAs, 2 ribosomal RNAs) and 2 conserved noncoding elements; the control region (D-Loop) and the origin of light strand synthesis (OL). Among the protein-coding genes, unusual start codons were identified in ND2, COX1 and ND3 genes and incomplete stop codons were identified in seven genes. Phylogenetic analysis with the currently known mitogenomes in genus Lutjanus revealed thatL. fulviflammawas most closely related toLutjanus russelliiwith 91% sequence identity.

关键词： High-throughput sequencing Lutjanidae mitogenome snapper coral reef

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Fall detection algorithm for the elderly using acceleration sensors on the shoes

Fall detection algorithm for the elderly using acceleration ...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： S. Y. Sim H. S. Jeon G. S. Chung S. K. Kim S. J. Kwon W. K. Lee K. S. Park Interdisciplinary program of bioengineering College of Engineering Seoul national university Department of biomedical engineering College of Medicine Seoul National University

ISBN: (纸本)9781424441211

The rate of increase in the number of aging population in Korea is very rapid among OECD-member countries. And fall accident is one of the most common factors that threaten the health of the elderly. Therefore, it is needed to develop a fall detection system for the elderly. Most fall detection systems use accelerometers attached on the torso. And in various studies, it was verified that these systems have high sensitivity and high specificity. However, the elderly would feel uncomfortable when banding a sensor on the chest every day. Therefore, in this study, we attached an accelerometer on the shoes to detect fall in the elderly. This prototype system would be improved as a smaller, low-power system in the next study. Also, applying energy harvesting device to this shoe system is being developed to reduce the weight of battery.

关键词： footwear Detection systems acceleration transducer aged person accelerometers falls Fall Autumn Detection algorithms Torso energy harvesting accidents and falls

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