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Spike train distance metric reveals plasticity in discrimination of salient calls by putative excitatory cells of the auditory cortex

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BMC Neuroscience 2012年第1期13卷 1-2页

作者： Charles L Zhao Frank Lin Robert C Liu Biomedical Engineering Graduate Program Coulter Department of Biomedical Engineering at Georgia Institute of Technology and Emory University Atlanta GA 30332 USA Interdisciplinary Bioengineering Graduate Program Coulter Department of Biomedical Engineering at Georgia Institute of Technology and Emory University Atlanta GA 30332 USA Department of Biology Emory University Atlanta GA 30322 USA

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HRV Analysis and Blood Pressure Monitoring on Weighing Scale using BCG

HRV Analysis and Blood Pressure Monitoring on Weighing Scale...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Jae Hyuk Shin Kwang Suk Park Interdisciplinary program of Biomedical Engineering Seoul National University KOREA. He is now with the Samsung Electronics Co. KOREA Department of Biomedical Engineering Seoul National University KOREA

ISBN: (纸本)9781424441198

Using the Ballistocardiogram(BCG) measured on weighing scale, heart rate variability(HRV) and blood pressure were estimated. BCG was measured while subjects were on weighing scale in resting state and under the Valsalva maneuver and static exercise condition to induce the change in cardiac autonomic rhythm. Time domain, frequency domain and nonlinear HRV parameters were estimated from the measured BCG and compared with the ones calculated from ECG measured simultaneously. For blood pressure(BP) estimation, ECG was measured additionally on the feet using dry electrodes simultaneously installed on weighing scale and R-J intervals were extracted as a BP correlated parameter at every beat cycle. HRV estimation results shows the correlation higher than 0.97, and the estimated BP was similar to the measured BP with a reliable correlations.

关键词： Ballistocardiogram(BCG) induce the change weighing scale

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Appropriate feeding for early juvenile stages of eunicid polychaete Marphysa sanguinea

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Fisheries and Aquatic Sciences 2017年第1期20卷 1-9页

作者： Kim, Kyeong Hun Kim, Byoung Kwon Kim, Sung Kyun Phoo, War War Venmathi Maran, B.A. Kim, Chang-Hoon Pukyong National University Interdisciplinary Program of Biomedical Engineering Busan 48513 South Korea Pukyong National University Department of Marine Bio-materials and Aquaculture Busan 48513 South Korea Pukyong National University Fisheries Science and Technology Centre Goseong-gun Gyeongsangnam-do 52957 South Korea

Survival rate (SR) and growth rate (GR) were tested with various feed sources to identify an appropriate feed to improve the productivity in the early life stage of the rock worm Marphysa sanguinea (Montagu, 1813) (Eunicidae: Polychaeta). In addition, feed supply rates were also examined. Three experiments were performed to identify the appropriate feed for the juvenile stages of M. sanguinea. Experiment 1 was done using seven different feed sources and without feed as well for the first 20days of M. sanguinea culture. Decapsulated Artemia and extruded pellet for shrimp were showed with high SR and GR in the experiment 1. Experiment 2 was performed with five different feed sources. Two feeds were selected from experiment 1 in addition to eel feed, mixed micro-algae, and benthic diatom. Four different quantities of each feed were supplied to 3000 individuals of early juvenile stage of M. sanguinea. High quantity of decapsulated Artemia and shrimp feed resulted with a relatively good SR and GR. In experiment 3, we provided 20, 50, and 75mg of decapsulated Artemia and shrimp feed to 3000 individuals of M. sanguinea. Our results demonstrated that after 3months, decapsulated Artemia showed high survival rate and 75mg/3000 inds provided the best quantity of feed in the earlier life stage culture of M. sanguinea. © 2017 The Author(s).

关键词： Decapsulated Artemia Feed Feeding rate Marphysa sanguinea Polychaete

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A portable flow cytometer with simultaneous detection of impedance and fluorescence

A portable flow cytometer with simultaneous detection of imp...

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13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009

作者： Kim, Kee Hyun Joo, Segyeong Noh, Jong Min Chung, Taek Dong Kim, Hee Chan Interdisciplinary Program Graduate School Seoul National University Korea Republic of Institute of Medical and Biological Engineering Medical Research Center Seoul National University Korea Republic of Department of Chemistry Seoul National University Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Korea Republic of

ISBN: (纸本)9780979806421

A portable flow cytometer with simultaneous detection of impedance and fluorescence was constructed incorporating polyelectrolytic gel electrodes (PGE) based impedance measurement and fluorescence measurement with integrated solid-state photonic devices. Simultaneous detection of fluorescence and impedance signal was performed with fluorescent and plain beads. The fluorescence and impedance signal were in good sync with flow of beads. © 2009 CBMS.

关键词： Fluorescence

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Automatic control of assist flow in totally implantable left ventricular assist device using variable pump rate

Automatic control of assist flow in totally implantable left...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： Jonghoon Choi Jaesoon Choi Youngho Jo Wukeun Kim Byunggoo Min Interdisciplinary Program of Medical and Biological Engineering Graduate School Japan Department of Biomedical Engineering College of Medicine Seoul National University South Korea

In this study, the automatic control algorithm in implantable left ventricular assist device to regulate cardiac output to the extent of preventing atrial-collapse and the high left atrial pressure (LAP) is proposed. Intersac pressure (ISP) waveform which reflects the status of left atrial pressure is used in automatic control. By analyzing the relationship between LAP and the negative peak of ISP, the equation for making the reference of PI-controller was set. By using the reference equation the proposed automatic controller which regulates the assist flow was designed. Through mock circulatory experiments and animal experiment, the automatic control algorithm was evaluated.

关键词： Automatic control Equations Blood Algorithm design and analysis biomedical engineering Pi control engineering in medicine and biology Educational institutions Electronic mail Animals

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The molecular characterization of complete mitochondrial genome of spotted snakehead fish,Channa punctata(Bloch 1793)

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Mitochondrial DNA Part B 2019年第1期4卷 547-548页

作者： Md. Jobaidul Alam Sapto Andriyono Sinar Pagi Sektiana Md. Mofizur Rahman Hyun-Woo Kim Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaDepartment of Fisheries Ministry of Fisheries and Livestock Dhaka Bangladesh Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaFisheries and Marine Faculty Universitas Airlangga Surabaya East Java Indonesia Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaAquaculture Technology Study Program Sekolah Tinggi Perikanan Jakarta Indonesia Department of Marine Biology Pukyong National University Busan Republic of KoreaDepartment of Fisheries and Marine Science Noakhali Science and Technology University Sonapur Noakhali Bangladesh Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaDepartment of Marine Biology Pukyong National University Busan Republic of Korea

The complete mitochondrial genome of spotted snakehead fish,Channa punctata(Bloch 1793) was determined by MiSeq platform. The genome was 16,409 bp in length, in which canonical 13 protein-coding genes, 22 tRNAs, 2 rRNAs, and a control region (D-Loop) were encoded. Relatively higher overall A + T contents (53.70%) was identified compared with G + C contents (46.30%). Among 13 protein-coding genes, only one unusual start condon (GTG) was identified in COX1, whereas six genes includingCOXII,COXIII,NAD2,NAD3,NAD4, andCytbwere ended with the incomplete stop codons (TA-/T–). Based on the currently identified mitogenomes of Channa fish species,C. punctatawas most closely related toChanna gachuawith 82% sequence identity.

关键词： Next generation sequencing Channa punctata mitochondrial genome phylogeny snakehead fish

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A home-based bedside monitoring system of ECG via bluetooth protocol

A home-based bedside monitoring system of ECG via bluetooth ...

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IEEE EMBS Asian-Pacific Conference on biomedical engineering 2003, APBME 2003

作者： Seo, Jin Woo Ryu, Myung Suk Park, Kwang Suk Jeong, Do-Un Interdisciplinary Program-Biomedical Engineering Major Graduate School Seoul National University Korea Republic of Advanced Biometric Research Center Seoul National University Korea Republic of Department of Biomedical Engineering Seoul National University College of Medicine Korea Republic of Dept. of Psychiatry Div. of Sleep Studies Seoul Nat'l Univ. College of Medicine and Hospital Korea Republic of

ISBN: (纸本)0780379438

Despite that ECG(electrocardiogram) provides substantial amount of information about a monitored patient, it has limitations when monitored remotely. In order to overcome long wire and channel interference problems of monitoring, wc used a certified Bluetooth Protocol and developed a home-based bedside ECG monitoring system. Bluetooth Protocol enabled the real-time transfer of ECG data via wireless communication with display and storage on PC(pcrsonal computer). We wore also able to retransmit the stored data to other site via TCP/IP. This system has clinical utility for unconstrained monitoring of ECG at bedside not only at home but also in hospital settings. © 2003 IEEE.

关键词： Electrocardiograms

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Clinical text generation through leveraging medical concept and relations

arXiv

引用

arXiv 2019年

作者： Lee, Wangjin Park, Hyeryun Yoon, Jooyoung Kim, Kyeongmo Choi, Jinwook Interdisciplinary Program in Bioengineering Graduate School Seoul National University Department of Biomedical Engineering College of Medicine Seoul National University

With a neural sequence generation model, this study aims to develop a method of writing the patient clinical texts given a brief medical history. As a proof-of-a-concept, we have demonstrated that it can be workable to use medical concept embedding in clinical text generation. Our model was based on the Sequence-to-Sequence architecture and trained with a large set of de-identified clinical text data. The quantitative result shows that our concept embedding method decreased the perplexity of the baseline architecture. Also, we discuss the analyzed results from a human evaluation performed by medical doctors. Copyright © 2019, The Authors. All rights reserved.

关键词： Embeddings

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Characterization of complete mitochondrial genome of coonstriped shrimpPandalus hypsinotus(Decapoda: Pandalidae)

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Mitochondrial DNA Part B 2019年第1期4卷 294-295页

作者： Nack-keun Kim Sapto Andriyono Kyung Mi Jung Gwang Ho Choi Tae-Ho Yoon Hyun-Woo Kim Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of Korea Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaDepartment of Marine Fisheries and Marine Faculty Universitas Airlangga C Campus Jl. Mulyorejo Surabaya East Java Indonesia Dokdo Fisheries Research Center National Institute of Fisheries Science Pohang Republic of Korea Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaDepartment of Marine Biology Pukyong National University Busan Republic of Korea

The complete mitochondrial genome of the coonstriped,Pandalus hypsinotuswas determined by the MiSeq sequencing platform. The mitogenome ofP. hypsinotus(15,909 bp) encoded the 13 protein-coding genes, 22 tRNA genes, two rRNA genes, non-coding, control region (D-Loop). Phylogenetic analysis based on the full mitochondrial genome sequences showed thatP. hypsinotusis most closely related toP. borealis(86%) clustering together withChlorotocus crassicornisin Pandalidae. The complete mitogenome sequence ofP. hypsinotuswould contribute to the scientific management for conservation of its resources in East/Japan Sea.

关键词： Next-generation sequencing decapoda mitogenome Dokdo Pandalidae

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Highly Wearable Galvanic Skin Response Sensor using Flexible and Conductive Polymer Foam

Highly Wearable Galvanic Skin Response Sensor using Flexible...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Jeehoon Kim Sungjun Kwon Sangwon Seo Kwangsuk Park Interdisciplinary Program of Bioengineering Seoul National University Seoul Korea Department of Biomedical Engineering Seoul National University Seoul Korea

Owing to advancements in daily physiological monitoring technology, diverse healthcare applications have emerged recently. The monitoring of skin conductance responses has extensive feasibility to support healthcare applications such as detecting emotion changes. In this study, we proposed a highly wearable and reliable galvanic skin response (GSR) sensor that measures the signals from the back of the user. To enhance its wearability and usability, we employed flexible conductive foam as the sensing material and designed it to be easily attachable to (and detachable from) a wide variety of clothes. We evaluated the sensing reliability of the proposed sensor by comparing its signal with a reference GSR. The average correlation between the two signals was 0.768;this is sufficiently high to validate the feasibility of the proposed sensor for reliable GSR sensing on the back.

关键词： Skin Correlation Sensors Reliability Electrodes biomedical monitoring Fingers

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