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Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer (Dec, 10.1038/s41467-019-13824-9, 2022)

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NATURE COMMUNICATIONS 2022年第1期13卷 1-1页

作者： Sieverling, Lina Hong, Chen Koser, Sandra D. Ginsbach, Philip Kleinheinz, Kortine Hutter, Barbara Braun, Delia M. Cortes-Ciriano, Isidro Xi, Ruibin Kabbe, Rolf Park, Peter J. Eils, Roland Schlesner, Matthias Brors, Benedikt Rippe, Karsten Jones, David T. W. Feuerbach, Lars Division of Applied Bioinformatics German Cancer Research Center (DKFZ) 69120 Heidelberg Germany Faculty of Biosciences Heidelberg University 69120 Heidelberg Germany Division of Applied Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Biosciences Heidelberg University Heidelberg Germany Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) 69120 Heidelberg Germany Department for Bioinformatics and Functional Genomics Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant 69120 Heidelberg Germany Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany Institute of Pharmacy and Molecular Biotechnology and BioQuant Heidelberg University Heidelberg Germany German Cancer Consortium (DKTK) Heidelberg Germany National Center for Tumor Diseases (NCT) Heidelberg Heidelberg Germany Heidelberg Center for Personalized Oncology (DKFZ-HIPO) German Cancer Research Center (DKFZ) Heidelberg Germany German Cancer Consortium (DKTK) German Cancer Research Center (DKFZ) Heidelberg Germany Division of Chromatin Networks German Cancer Research Center (DKFZ) and BioQuant 69120 Heidelberg Germany Department of Biomedical Informatics Harvard Medical School Boston Massachusetts 02115 USA Department of Chemistry Centre for Molecular Science Informatics University of Cambridge Cambridge CB2 1EW UK Ludwig Center at Harvard Medical School Boston Massachusetts 02115 USA Department of Biomedical Informatics Harvard Medical School Boston MA USA Department of Chemistry Centre for Molecular Science Informatics University of Cambridge Cambridge UK Ludwig Center at Harvard Medical School Boston MA USA School of Mathematical Sciences and Center for Statistical Science Peking University Beijing 100871 China Heidelberg University Heidelberg Germany New BIH Digital Health Center Berlin Institute of Health (BIH) and Charité - Universitätsmedizin Berlin Berlin Germany Bioi

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Analysis on output polarization characteristics of fiber comb filters based on polarization-diversity loop structure

Analysis on output polarization characteristics of fiber com...

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International Conference on Photonics, Optics and Laser Technology (PHOTOPTICS)

作者： Songhyun Jo Kyoungsoo Park Sung Wook Choi Seul Lee Lee Jun Hyeog Jeong Jihoon Kim Yong Wook Lee School of Interdisciplinary Program of Biomedical Mechanical & Electrical Engineering Pukyong National University Busan Republic of Korea School of Electrical Engineering Pukyong National University Busan Korea Republic of

ISBN: (纸本)9781509058860

The output states of polarization (SOP's) were investigated within the bandwidth of a filter channel (0.8 nm) for a variety of optical fiber comb filters based on polarization-diversity loop structure including a zeroth-order comb filter, first-order Lyot-type and Solc-type comb filters, and a second-order Solc-type comb filter. The output SOP's (SOP out 's) of the filters were calculated at a flat-top band operation mode of each filter for four different input SOP's (SOP in 's) except for the zeroth-order filter. It was found that the SOP out of each filter had unique dependence on wavelength. Specifically, the SOP out 's of first-order and second-order comb filters vary periodically with spectral periods of a channel bandwidth (0.8 nm) and its half (0.4 nm), respectively. If an output linear polarizer is located at the output port of each filter, the specific portion of transmission spectra can be passed or rejected, and the rejected band can be continuously tuned in a limited wavelength range by controlling the SOP in . Moreover, the SOP in can be figured out by analyzing the location of the spectral dip at the output transmission spectra obtained above by using the output polarizer.

关键词： Optical fiber filters Optical fiber polarization Bandwidth Maximum likelihood detection Nonlinear filters Optical fiber couplers

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Temperature-dependent transport properties in vanadium dioxide thin films 11

Temperature-dependent transport properties in vanadium dioxi...

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11th Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2015

作者： Choi, J. Kim, B.-J. Seo, G. Lee, Y.W. School of Electrical Engineering Pukyong National University Busan608-737 Korea Republic of Mobrik Co. Ltd. Daejeon305-700 Korea Republic of Natural Sciences Research Institute KAIST Daejeon305-701 Korea Republic of Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan608-737 Korea Republic of

In VO2, which is a promising strongly correlated material of electro-optics, temperature-dependent electrical transport properties were investigated by using ordinary Hall effect measurement. The interesting variation... 详细信息

ISBN: (纸本)9781467371094

关键词： Vanadium dioxide

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NextGen advises "Trying to Manage"

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Science (New York, N.Y.) 2019年第6461期366卷 28-30页

作者： Douglas Steinhauff Joel Henrique Ellwanger Monika Lewinska Edmond Sanganyado Yongsheng Ji Buddini Iroshika Karawdeniya Naike Bochatay Eric Britt Moore Aminata Coulibaly Shaima Ibrahim Déna Skye Jansen Joshua I James David M Cole Anna Lipkin Beth McKinnon Adamowicz Carl M Cohen Shervin Fatehi Maria Helena Holmstrom Rosa Li Department of Biomedical Engineering University of Utah Salt Lake City UT 84112 USA. dbsteinh@***. Department of Genetics Universidade Federal do Rio Grande do Sul Porto Alegre Rio Grande do Sul 91501-970 Brazil. joel.ellwanger@***. Biotech Research and Innovation Centre Faculty of Medicine University of Copenhagen Copenhagen 2200 Denmark. monika.lewinska@bric.ku.dk. Marine Biology Institute Shantou University Shantou Guangdong 515063 China. Department of Human Parasitology Anhui Medical University Hefei Anhui 230032 China. jiyongshengkey@***. Department of Mechanical Engineering Southern Methodist University Dallas TX 75206 USA. bkarawdeniya@smu.edu. Department of Pediatrics Division of Pediatric Critical Care University of California San Francisco San Francisco CA 94143 USA. Department of Agronomy Iowa State University Ames IA 50011 USA. ebm256@iastate.edu. Departments of Neurology and Neuroscience University of Virginia Charlottesville VA 22908 USA. Department of Chemistry The American University in Cairo Cairo 11321 Egypt. Rxshaima@***. Department of Environmental & Geographical Science University of Cape Town Cape Town Western Cape 7700 South Africa. djvirgo17@***. Legal Informatics and Forensic Science Institute Hallym University Chuncheon Gangwon 24252 South Korea. joshua.i.james@hallym.ac.kr. Interdisciplinary Program in Neuroscience Utah State University Logan UT 84322-7000 USA. dcole@***. Department of Neuroscience University of California San Francisco San Francisco CA 94158 USA. Department of Genetics Cell Biology and Development University of Minnesota Minneapolis MN 55455 USA. Science Management Associates Newton MA 02458 USA. Department of Chemistry The University of Texas Rio Grande Valley Edinburg TX 78539-2909 USA. shervin.fatehi@utrgv.edu. Department of Neuroscience Gothenburg University KlinKem Sahlgrenska Akademin GU Gothenburg 40530 Sweden. maria.holmstrom@gu.se. Duke Institute for Brain Sciences Duke Univ

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A Reconfigurable DNA Accordion Rack

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Angewandte Chemie 2018年第11期130卷

作者： Yeongjae Choi Hansol Choi Amos C. Lee Hyunung Lee Sunghoon Kwon Department of Electrical and Computer Engineering Seoul National University 1 Gwanak-ro Gwanak-gu Seoul 08826 Republic of Korea Interdisciplinary Program for Bioengineering Seoul National University 1 Gwanak-ro Gwanak-gu Seoul 08826 Republic of Korea Institute of Entrepreneurial Bio Convergence Seoul National University 1 Gwanak-ro Gwanak-gu Seoul 08826 Republic of Korea Seoul National University Hospital Biomedical Research Institute Seoul National University Hospital 101 Daehak-ro Jongno-gu Seoul 03080 Republic of Korea

DNA nanostructure‐based mechanical systems that control the distance between elements of interest have demonstrated great potential for various applications, including nanoplasmonic systems, molecular reactors, and other nanotechnology platforms. However, previously reported systems could not collectively manipulate a 2D or 3D nanoscale network of elements to various forms in multiple stages. A reconfigurable DNA accordion rack structure is introduced that is a DNA beam lattice that changes its conformation with a small amount of short‐length DNA locks as the controlling input. The lattice shape of the 2D DNA accordion rack and the diameter and the height of the 3D DNA nanotubular structure made of the DNA accordion rack could be controlled. Furthermore, by sequentially repeating the detachment and the attachment of the different DNA locks using strand displacement, the shape reconfiguration was repeatedly carried out.

关键词： DNA-Nanomaschinen DNA-Nanotechnologie DNA-Strukturen Nanoporen Selbstorganisation

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Laminar lifted methane jet flames in coflow-air diluted with helium and nitrogen 10

Laminar lifted methane jet flames in coflow-air diluted with...

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10th Asia-Pacific Conference on Combustion, ASPACC 2015

作者： Sapkal, Narayan P. Lee, Won June Park, Jeong Kwon, Oh Boong Department of Mechanical Engineering Pukyong National University Korea Republic of Interdisciplinary Program of Biomedical Engineering Pukyong National University Korea Republic of

Laminar lifted methane jet flames in co-flow air diluted with helium and nitrogen have been investigated experimentally. Such methane jet flames could be also lifted even at nozzle exit velocities much higher than the stoichiometric laminar flame speed despite the Schmidt number less than unity. The chemiluminescence intensities of OH∗ radical (good indicator of heat release rate), and the radius of curvature for triple flame were measured using an intensified charge-coupled device (ICCD) camera and digital camera at various conditions. The lifted flames were stabilized due to buoyancy-induced convection in buoyancy-dominated regime, causing an increase of reactant mass flux to edge flame and thereby increasing the reaction rate and subsequently edge flame speed. It was confirmed that increased OH∗ concentration caused an increase of edge flame speed via enhanced chemical reaction in buoyancy-dominated regime. In jet-momentum-dominated regime, an increase in radius of curvature in addition to the increased OH∗ concentration stabilizes such lifted flames. Based on the stabilization mechanism, detailed discussion on the stabilization of such lifted flame is made.

关键词： Methane

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Driver drowsiness detection using the in-ear EEG

Driver drowsiness detection using the in-ear EEG

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Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： Taeho Hwang Miyoung Kim Seunghyeok Hong Kwang Suk Park Samsung Electronics DMC Research Center Seoul South Korea Interdisciplinary Program in Bioengineering Seoul National University Seoul South Korea Department of Biomedical Engineering Seoul National University College of Medicine Seoul South Korea

ISBN: (纸本)9781457702198

Driver drowsiness monitoring is one of the most demanded technologies for active prevention of severe road accidents. Electroencephalogram (EEG) and several peripheral signals have been suggested for the drowsiness monitoring. However, each type of signal has partial limitations in terms of either convenience or accuracy. Recent emerged concept of in-ear EEG raises expectations due to reduced obtrusiveness. It is yet unclear whether the in-ear EEG is effective enough for drowsiness detection in comparison with on-scalp EEG or peripheral signals. In this work, we evaluated performance of the in-ear EEG in drivers' alertness-drowsiness classification for the first time. Simultaneously, we also tested three peripheral signals including electrocardiogram (ECG), photoplethysmogram (PPG), and galvanic skin response (GSR) which have advantage in convenience of measurement. The classification analysis using the in-ear EEG resulted in high classification accuracy comparable to that of the individual on-scalp EEG channels. The ECG, PPG and GSR showed competitive performance but only when used together in pairwise combinations. Our results suggest that the in-ear EEG would be viable alternative to the single channel EEG or the individual peripheral signals for the drowsiness monitoring.

关键词： Electroencephalography Electrocardiography Monitoring Vehicles Wheels Standards Ear

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Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021

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The Lancet 2023年第10397期402卷 203-234页

作者： Ong, Kanyin Liane Stafford, Lauryn K. McLaughlin, Susan A. Boyko, Edward J. Vollset, Stein Emil Smith, Amanda E. Dalton, Bronte E. Duprey, Joe Cruz, Jessica A. Hagins, Hailey Lindstedt, Paulina A. Aali, Amirali Abate, Yohannes Habtegiorgis Abate, Melsew Dagne Abbasian, Mohammadreza Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Mohsen ElHafeez, Samar Abd Abd-Rabu, Rami Abdulah, Deldar Morad Abdullah, Abu Yousuf Md Abedi, Vida Abidi, Hassan Aboagye, Richard Gyan Abolhassani, Hassan Abu-Gharbieh, Eman Abu-Zaid, Ahmed Adane, Tigist Demssew Adane, Denberu Eshetie Addo, Isaac Yeboah Adegboye, Oyelola A. Adekanmbi, Victor Adepoju, Abiola Victor Adnani, Qorinah Estiningtyas Sakilah Afolabi, Rotimi Felix Agarwal, Gina Aghdam, Zahra Babaei Agudelo-Botero, Marcela Arriagada, Constanza Elizabeth Aguilera Agyemang-Duah, Williams Ahinkorah, Bright Opoku Ahmad, Danish Ahmad, Rizwan Ahmad, Sajjad Ahmad, Aqeel Ahmadi, Ali Ahmadi, Keivan Ahmed, Ali Ahmed, Luai A. Ahmed, Syed Anees Ajami, Marjan Akinyemi, Rufus Olusola Al Hamad, Hanadi Al Hasan, Syed Mahfuz AL-Ahdal, Tareq Mohammed Ali Alalwan, Tariq A. Al-Aly, Ziyad AlBataineh, Mohammad T. Alcalde-Rabanal, Jacqueline Elizabeth Alemi, Sharifullah Ali, Hassam Alinia, Tahereh Aljunid, Syed Mohamed Almustanyir, Sami Al-Raddadi, Rajaa M. Alvis-Guzman, Nelson Amare, Firehiwot Ameyaw, Edward Kwabena Amiri, Sohrab Amusa, Ganiyu Adeniyi Andrei, Catalina Liliana Anjana, Ranjit Mohan Ansar, Adnan Ansari, Golnoosh Ansari-Moghaddam, Alireza Anyasodor, Anayochukwu Edward Arabloo, Jalal Aravkin, Aleksandr Y. Areda, Demelash Arifin, Hidayat Arkew, Mesay Armocida, Benedetta Arnlov, Johan Artamonov, Anton A. Arulappan, Judie Aruleba, Raphael Taiwo Arumugam, Ashokan Aryan, Zahra Asemu, Mulu Tiruneh Asghari-Jafarabadi, Mohammad Askari, Elaheh Asmelash, Daniel Astell-Burt, Thomas Athar, Mohammad Athari, Seyyed Shamsadin Atout, Maha Moh'd Wahbi Avila-Burgos, Leticia Awaisu, Ahmed Azadnajafabad, Sina Darshan, B.B. Babamohamadi, Hassan Badar, Muhammad Badawi, Alaa Badiye, Ashish D. Baghcheghi, Nayereh Baghe Institute for Health Metrics and Evaluation School of Medicine General Medicine Service Department of Veterans Affairs Seattle WA United States Department of Health Metrics Sciences School of Medicine Faculty of Medicine France Department of Clinical Governance and Quality Improvement Aleta Wondo Hospital Aleta Wondo Ethiopia Department of Nursing Woldia University Woldia Ethiopia Department of Nursing Department of Orthopedic Surgery Orthopaedic Surgery Social Determinants of Health Research Center Non-communicable Diseases Research Center Epidemiology Department Evidence-Based Practice Center Community and Maternity Nursing Unit University of Duhok Duhok Iraq School of Planning Faculty of Environment Department of Public Health Sciences Penn State College of Medicine Pennsylvania State University Hershey PA United States Biocomplexity Institute Virginia Tech Blacksburg VA United States College of Medicine Department of Public Health Laboratory Technology Sciences Department Department of Family and Community Health University of Health and Allied Sciences Ho Ghana Research Center for Immunodeficiencies Department of Biosciences and Nutrition Karolinska University Hospital Huddinge Sweden Clinical Sciences Department Department of Surgery Department of Surgery Department of Obstetrics & Gynecology College of Graduate Health Sciences University of Tennessee Memphis TN United States Department of Obstetrics & Gynecology Department of Clinical and Psychosocial Epidemiology Department of Anesthesia and Critical Care Centre for Social Research in Health Quality and Systems Performance Unit Cancer Institute NSW Sydney NSW Australia Department of Public Health and Tropical Medicine HIV and Infectious Diseases Department Jhpiego Abuja Nigeria Adolescent Research and Care Department Adolescent Friendly Research Initiative and Care Ado Ekiti Nigeria Department of Epidemiology Department of Epidemiology and Medical Statistics Department of Family Medicine McMaster University

Background: Diabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), we produced location-specific, age-specific, and sex-specific estimates of diabetes prevalence and burden from 1990 to 2021, the proportion of type 1 and type 2 diabetes in 2021, the proportion of the type 2 diabetes burden attributable to selected risk factors, and projections of diabetes prevalence through 2050. Methods: Estimates of diabetes prevalence and burden were computed in 204 countries and territories, across 25 age groups, for males and females separately and combined;these estimates comprised lost years of healthy life, measured in disability-adjusted life-years (DALYs;defined as the sum of years of life lost [YLLs] and years lived with disability [YLDs]). We used the Cause of Death Ensemble model (CODEm) approach to estimate deaths due to diabetes, incorporating 25 666 location-years of data from vital registration and verbal autopsy reports in separate total (including both type 1 and type 2 diabetes) and type-specific models. Other forms of diabetes, including gestational and monogenic diabetes, were not explicitly modelled. Total and type 1 diabetes prevalence was estimated by use of a Bayesian meta-regression modelling tool, DisMod-MR 2.1, to analyse 1527 location-years of data from the scientific literature, survey microdata, and insurance claims;type 2 diabetes estimates were computed by subtracting type 1 diabetes from total estimates. Mortality and prevalence estimates, along with standard life expectancy and disability weights, were used to calculate YLLs, YLDs, and DALYs. When appropriate, we extrapolated estimates to a hypothetical population with a standardised age structure to allow comparison in populations with different age structures. We used the comparative r

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Single Cell Genomics: Whole Genome Sequencing of Single Circulating Tumor Cells Isolated by Applying a Pulsed Laser to Cell-Capturing Microstructures (Small 37/2019)

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Small 2019年第37期15卷

作者： Okju Kim Daewon Lee Amos Chungwon Lee Yongju Lee Hyung Jong Bae Han-Byoel Lee Ryong Nam Kim Wonshik Han Sunghoon Kwon Department of Electrical and Computer Engineering Institute of Engineering Research Seoul National University 1 Gwanak-ro Gwanak-gu Seoul 08826 Republic of Korea Interdisciplinary Program in Bioengineering Seoul National University 1 Gwanak-ro Gwanak-gu Seoul 08826 Republic of Korea BK21+ Creative Research Engineer Development for IT Seoul National University 1 Gwanak-ro Gwanak-gu Seoul 08826 Republic of Korea Nano Systems Institute Seoul National University 1 Gwanak-ro Gwanak-gu Seoul 08826 Republic of Korea Department of Surgery Seoul National University College of Medicine 101 Daehak-ro Jongno-gu Seoul 03080 Republic of Korea Biomedical Research Institute Seoul National University Hospital 101 Daehak-ro Jongno-gu Seoul 03080 Republic of Korea Cancer Research Institute Seoul National University 101 Daehak-ro Jongno-gu Seoul 03080 Republic of Korea Institutes of Entrepreneurial BioConvergence Seoul National University 1 Gwanak-ro Gwanak-gu Seoul 08826 Republic of Korea Inter-University Semiconductor Research Center 1 Gwanak-ro Gwanak-gu Seoul 08826 Republic of Korea

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Author Correction: The power of genetic diversity in genome-wide association studies of lipids

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Nature 2023年第7965期618卷 E19-E20页

作者： Sarah E Graham Shoa L Clarke Kuan-Han H Wu Stavroula Kanoni Greg J M Zajac Shweta Ramdas Ida Surakka Ioanna Ntalla Sailaja Vedantam Thomas W Winkler Adam E Locke Eirini Marouli Mi Yeong Hwang Sohee Han Akira Narita Ananyo Choudhury Amy R Bentley Kenneth Ekoru Anurag Verma Bhavi Trivedi Hilary C Martin Karen A Hunt Qin Hui Derek Klarin Xiang Zhu Gudmar Thorleifsson Anna Helgadottir Daniel F Gudbjartsson Hilma Holm Isleifur Olafsson Masato Akiyama Saori Sakaue Chikashi Terao Masahiro Kanai Wei Zhou Ben M Brumpton Humaira Rasheed Sanni E Ruotsalainen Aki S Havulinna Yogasudha Veturi QiPing Feng Elisabeth A Rosenthal Todd Lingren Jennifer Allen Pacheco Sarah A Pendergrass Jeffrey Haessler Franco Giulianini Yuki Bradford Jason E Miller Archie Campbell Kuang Lin Iona Y Millwood George Hindy Asif Rasheed Jessica D Faul Wei Zhao David R Weir Constance Turman Hongyan Huang Mariaelisa Graff Anubha Mahajan Michael R Brown Weihua Zhang Ketian Yu Ellen M Schmidt Anita Pandit Stefan Gustafsson Xianyong Yin Jian'an Luan Jing-Hua Zhao Fumihiko Matsuda Hye-Mi Jang Kyungheon Yoon Carolina Medina-Gomez Achilleas Pitsillides Jouke Jan Hottenga Gonneke Willemsen Andrew R Wood Yingji Ji Zishan Gao Simon Haworth Ruth E Mitchell Jin Fang Chai Mette Aadahl Jie Yao Ani Manichaikul Helen R Warren Julia Ramirez Jette Bork-Jensen Line L Kårhus Anuj Goel Maria Sabater-Lleal Raymond Noordam Carlo Sidore Edoardo Fiorillo Aaron F McDaid Pedro Marques-Vidal Matthias Wielscher Stella Trompet Naveed Sattar Line T Møllehave Betina H Thuesen Matthias Munz Lingyao Zeng Jianfeng Huang Bin Yang Alaitz Poveda Azra Kurbasic Claudia Lamina Lukas Forer Markus Scholz Tessel E Galesloot Jonathan P Bradfield E Warwick Daw Joseph M Zmuda Jonathan S Mitchell Christian Fuchsberger Henry Christensen Jennifer A Brody Mary F Feitosa Mary K Wojczynski Michael Preuss Massimo Mangino Paraskevi Christofidou Niek Verweij Jan W Benjamins Jorgen Engmann Rachel L Kember Roderick C Slieker Ken Sin Lo Nuno R Zilhao Phuong Le Marcus E Kleber Graciela E Delgado Shaofeng Huo Dai Department of Internal Medicine Division of Cardiology University of Michigan Ann Arbor MI USA. VA Palo Alto Health Care System Palo Alto CA USA. Department of Medicine Division of Cardiovascular Medicine Stanford University School of Medicine Stanford CA USA. Department of Computational Medicine and Bioinformatics University of Michigan Ann Arbor MI USA. William Harvey Research Institute Barts and the London School of Medicine and Dentistry Queen Mary University of London London UK. Department of Biostatistics and Center for Statistics Genetics University of Michigan Ann Arbor MI USA. Department of Genetics Perelman School of Medicine University of Pennsylvania Philadelphia PA USA. Clinical Pharmacology William Harvey Research Institute Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK. Endocrinology Boston Children's Hospital Boston MA USA. Medical and Population Genetics Broad Institute Cambridge MA USA. Department of Genetic Epidemiology University of Regensburg Regensburg Germany. McDonnell Genome Institute and Department of Medicine Washington University St Louis MO USA. Department of Precision Medicine Division of Genome Science National Institute of Health Cheongju-si South Korea. Tohoku Medical Megabank Organization Tohoku University Sendai Japan. Sydney Brenner Institute for Molecular Bioscience Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa. Center for Research on Genomics and Global Health National Human Genome Research Institute National Institutes of Health Bethesda MD USA. Blizard Institute Barts and the London School of Medicine and Dentistry Queen Mary University of London London UK. Wellcome Sanger Institute Hinxton UK. Department of Epidemiology Emory University Rollins School of Public Health Atlanta GA USA. Atlanta VA Health Care System Decatur GA USA. Malcolm Randall VA Medical Center Gainesville FL USA. Division of Vascular Sur

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