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检索条件"机构=Interdisciplinary Program in Biomedical Engineering"

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Development of a thrombus mimic in abdominal aortic aneurysms

Development of a thrombus mimic in abdominal aortic aneurysm...

引用

2007 ASME Summer Bioengineering Conference, SBC 2007

作者： Ashton, John H. Vande Geest, Jonathan P. Biomedical Engineering Interdisciplinary Program University of Arizona Tucson AZ United States Department of Aerospace and Mechanical Engineering University of Arizona Tucson AZ United States

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Cell chip to monitor the influence of electric field on the human mesendhymal stem cells 11

Cell chip to monitor the influence of electric field on the ...

引用

11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

作者： Kwon, Gu-Han Lee, Kwang Ho Lee, Eun-Joong Lee, Sang-Hoon Department of Biomedical Engineering College of Medicine Korea University Korea Republic of Interdisciplinary Program in Medical and Biological Engineering Major Seoul National University Korea Republic of

ISBN: (纸本)9780979806407

A new micro cell chip which can induce stem cells to differentiate into specific body cell types has been designed and fabricated for tissue engineering. This paper presents the fabrication and preliminary test results of a MEMS cell electric stimulator. It provides a new tool of cell electric stimulation, culture and analysis for stem cell research. This study provides the controlling proliferation as well as morphology of human mesenchymal stem cell on the microchip. DC 1V, 5V, 12V, AC 5V, 1 Hz, 1K Hz, 1M Hz were compared with electric stimulation for their impact on the expansion and morphology of mesenchymal stem cells (MSCs). It provides a new generation of cell culture, stimulation and analysis devices for stem cell research and tissue engineering. © 2007 CBMS.

关键词： Stem cells

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Second derivative of photoplethysmography for estimating vascular aging

Second derivative of photoplethysmography for estimating vas...

引用

6th International Special Topic Conference on ITAB, 2007

作者： Hyun, Jae Baek Jung, Soo Kim Yun, Sung Kim Haet, Bit Lee Kwang, Suk Park Interdisciplinary Program of Bioengineering Seoul National University Seoul Korea Republic of Interdisciplinary Program on Medical and Biological Engineering Seoul National University Seoul Korea Republic of Dept. of Biomedical Engineering College of Medicine Seoul National University Seoul Korea Republic of

ISBN: (纸本)9781424418688

Coronary artery disease (CAD) is one of the major causes of death. Therefore recurrent monitoring of arterial condition is important. The photoplethysmography (PPG) is simple and cost effective technique to measure blood volume change. As an application of PPG technique, the second derivative of photoplethysmography(SDPTG) was introduced for monitoring arterial condition. SDPTG consists of an a, b, c and d wave in systole and an e wave in diastole. The SDPTG wave pattern is determined by the proportions of the b, c, d, and e waves to the a wave. In the present study, it is confirmed that the b/a ratio and SDPTG-AI increased with age, and the c/a, d/a, and e/a ratios decreased with age. The informal method which substitutes formal SDPTG-AI was suggested. © 2008 IEEE.

关键词： Cost effectiveness

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Two unconstrained methods for blood pressure monitoring in a ubiquitous home healthcare

Two unconstrained methods for blood pressure monitoring in a...

引用

5th IASTED International Conference on biomedical engineering, BioMED 2007

作者： Jung, Soo Kim Ko, Keun Kim Yong, Gyu Lim Kwang, Suk Park Interdisciplinary Program in Biomedical Engineering Seoul National University Korea Republic of Advanced Biometric Research Center Seoul National University Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Korea Republic of

We proposed two unconstrained methods for blood pressure monitoring in a ubiquitous home healthcare. Instead of a conventional oscillometric method, unconstrained pulse arrival time was used. Pulse arrival time is the time delay between Electrocardiogram (ECG) and Photoplethysmogram (PPG). In first method, ECG and PPG could be unconstrainedly obtained in a computer desk environment. In second method, ECG and PPG could be measured in a toilet seat unconstrainedly. The relationship between systolic blood pressure and pulse arrival time was investigated with several experiments. Additionally, the potential of pulse arrival time for blood pressure monitoring was validated in a practical application in a daily life. It showed that these methods were useful for the long term monitoring in a telemedicine.

关键词： Electrocardiograms

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Activity energy expenditure assessment system based on activity classification using multi-site triaxial accelerometers

Activity energy expenditure assessment system based on activ...

引用

29th Annual International Conference of IEEE-EMBS, engineering in Medicine and Biology Society, EMBC'07

作者： Kim, Dongwoo Kim, Hee Chan Interdisciplinary Program Graduate School Seoul National University Seoul Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Seoul Korea Republic of

ISBN: (纸本)1424407885

Wireless networked multisite triaxial accelerometry system was proposed to estimate activity energy expenditure during daily life. Proposed system used different estimation algorithms according to activity classification based on measured acceleration signals. The estimation results showed higher correlation (R2 = 0.98) and smaller standard errors of estimation (SEE = 0.66 kcal) than any other system in preceding reports. © 2007 IEEE.

关键词： biomedical engineering

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Comparison of HRV spectral analysis methods for unconstrainedly measured ECG

Comparison of HRV spectral analysis methods for unconstraine...

引用

5th IASTED International Conference on biomedical engineering, BioMED 2007

作者： Ko, Keun Kim Jung, Soo Kim Byung, Hoon Choi Gih, Sung Chung Haet, Bit Lee Yong, Gyu Lim Kwang, Suk Park Interdisciplinary Program in Medical and Biological Engineering Seoul National University Korea Republic of Advanced Biometric Research Center Seoul National University Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Korea Republic of

For ubiquitous healthcare, interests for unconstrained method for ECG measurement have increased in the biomedical engineering field. Recently, capacitivecoupled method was introduced as the unconstrained method. However, the ECGs obtained from this method have many motion artefact noises, so heart rate data becomes intermittent finally. In this paper, spectral analysis methods of heart rate variability (HRV) for intermittent heart rate (HR) data are compared through simulation of artificial and real intermittent HR data. As the index of comparison, LF/HF ratio is used, which is a parameter reflecting the sympatho-vagal balance. In conclusion, the Burg's algorithm of parametric method has the lowest error, and the Lomb-Scargle (LS) periodogram of uneven method has the worst result. But, in low intermittent number, LS periodogram is the best.

关键词： Electrocardiograms

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Unconstrained heart rate estimation system in bed

Unconstrained heart rate estimation system in bed

引用

2nd International Conference on Convergent Information Technology, ICCIT 07

作者： Chung, Gih Sung Choi, Byoung Hoon Kim, Ko Keun Lim, Yong Gyu Choi, Jin Wook Jeong, Do-Un Park, Kwang Suk Interdisciplinary Program in Medical and Biological Engineering Seoul National University Korea Republic of Dept. of Neuropsychiatry Seoul National University College of Medicine and Hospital Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Korea Republic of Department of Oriental Biomedical Engineering Sangji University Wonju Korea Republic of

ISBN: (纸本)0769530389

It is widely known that autonomic Nervous System (ANS) is one of the indices to indicate the wakefulness of person. Therefore measuring the biosignals relating with the ANS during sleep is required to evaluate sleep quality. There are many researches that heart rate derived from the electrocardiogram (ECG) is good index to show the sympathetic or parasympathetic activities. To assess the quality of sleep, polysomnagraphy is used as golden standard but subjects have to attach many of sensors to their body and It is not only complicate, but also influence their sleep. In this study, to measure the autonomic nervous activities, we introduce newly developed system using load-cell. The sensors installed bottom of the bed measure the ballistocardiogram, mechanical vibration of heart. Ballistocardiogram is one of the nonintrusive methods to measure the heart rates unconstrainedly. By comparing with reference signal, ECG using Ag-AgCl electrodes, we validated our system with the four subjects. The results show comparison of LF/HF ratio, one of the heart rate variability, measured from the load-cells and Ag-AgCl electrodes for the each sleep stage, deep sleep, light sleep and REM sleep. It shows the different pattern for the light and deep sleep but contrary to our expectation, REM sleep doesn't indicate the highest value. LF/HF ratio measured from both methods have no significant differences. © 2007 IEEE.

关键词： Vibrations (mechanical)

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Implementation of the relay server for the Ubiquitous Integrated Biotelemetry System for Emergency Care (UIBSEC) based on 3.5G HSDPA technology

Implementation of the relay server for the Ubiquitous Integr...

引用

29th Annual International Conference of IEEE-EMBS, engineering in Medicine and Biology Society, EMBC'07

作者： Min, Yang Jung Jaemin, Kang Il, Hyung Shin Yoonseo, Koo Gil, Joon Suh Hee, Chan Kim Interdisciplinary Program Graduate School Seoul National University Seoul Korea Republic of Department of Emergency Medicine Seoul National University Seoul Korea Republic of Department of Biomedical Engineering Institute of Medical and Biological Engineering Seoul National University Seoul Korea Republic of

ISBN: (纸本)1424407885

When an emergent case occurs, to give proper and immediate emergency treatment to a patient is as important as to transfer him or her to the hospital as early as possible. For this circumstance where first aid usually happens in an ambulance, we developed the Ubiquitous Integrated Biotelemetry System for Emergency Care (UIBSEC) based on wireless 3.5G HSDPA module in order to provide more proper and active medical care to a patient. For this system we performed experimental tests on the HSDPA module to measure practical performance values with respect to throughput and RTT (round-trip-time) and compared the result with the theoretical specifications. In the course of developing this system we created the C#-based Network Solution Library (NSL) which helps drastically reducing the overhead. We applied this library to components of the UIBSEC - two kinds of clients and one central server - and confirmed that it works smoothly in wireless networks and it is useful in the future development process of network applications. © 2007 IEEE.

关键词： Servers

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Noninvasive heart rate variability analysis using loadcell-installed bed during sleep

Noninvasive heart rate variability analysis using loadcell-i...

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29th Annual International Conference of IEEE-EMBS, engineering in Medicine and Biology Society, EMBC'07

作者： Chung, Gih Sung Choi, Byoung Hoon Jeong, Do-Un Park, Kwang Suk Interdisciplinary Program in Medical and Biological Engineering Seoul National University Graduate School Korea Republic of Dept. of Neuropsychiatry College of Medicine and Hospital Seoul National University Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Korea Republic of

ISBN: (纸本)1424407885

Polysomnography is the standard method to score the sleep stages or to determine the quality of sleep. During all night examination, subjects must attach complicate and numerous electrodes on their body to acquire the biosignals. They can influence participants' sleep stage transition or sleep pattern, and the method seems intricate. In many researches, it is reported that autonomic nervous system (ANS) is varying with sleep stage transition and heart rate variability (HRV) is one of the indices which reflects the changes of autonomic nervous system. In this point of view, we can estimate the sleep quality by observing the HRV variation. In this study, to analyze the heart rate variability, we introduce a new system that can detect the heart beats of subjects during sleep by using bed installed load-cell sensors. The pressure to the sensor changes with the pulsation of the heart and we consider it as ballistocardiogram, the physical heart beat signal. To validate our system, we adopted this system for the 4 subjects with the polysomnography. The results show the LF/HF ratio of the heart rate, one of the reflection parameters of ANS, acquired from the system for each sleep stage. To validate the results, the HRV from electrocardiogram using Ag-AgCl electrodes will be compared. © 2007 IEEE.

关键词： biomedical engineering

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Segmentation of solid nodules in ultrasonographic breast image based on wavelet transform

Segmentation of solid nodules in ultrasonographic breast ima...

引用

29th Annual International Conference of IEEE-EMBS, engineering in Medicine and Biology Society, EMBC'07

作者： Park, Sangyun Kong, Hyoun-Joong Moon, Woo Kyoung Kim, Hee Chan Interdisciplinary Program Graduate School Seoul National University Seoul Korea Republic of Department of Radiology Seoul National University Seoul 110-744 Korea Republic of Department of Biomedical Engineering College of Medicine and Institute of Medical and Biological Engineering Seoul National University Seoul Korea Republic of

ISBN: (纸本)1424407885

An accurate segmentation of solid nodules in ultrasonographic (US) breast image is presented. 1-level 2-dimensional Discrete Wavelet Transform (DWT) is used to create features reflecting the texture information of the original image. Using these features, the texture classification is achieved. Finally, solid nodule region is segmented from the classified texture region. Proper threshold for texture classification is automatically decided. Empirically acquired information about the relationship between the texture characteristic of the original image and the optimal threshold is examined and used. Presented algorithm is applied to 284 malignant solid nodules and 300 benign solid nodules and the resulting images are presented. © 2007 IEEE.

关键词： Ultrasonography

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