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检索条件"机构=Interdisciplinary Program in Biomedical Engineering"

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Artificial neural network-based estimation of the eyeball position using the magnetic contact lens sensing technique

Artificial neural network-based estimation of the eyeball po...

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2005 27th Annual International Conference of the engineering in Medicine and Biology Society, IEEE-EMBS 2005

作者： Lee, Seung Yup Kim, Keun Young Kim, Hee Chan Interdisciplinary Program-Biomedical Engineering Major Graduate School Seoul National University Seoul Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Seoul Korea Republic of

ISBN: (纸本)0780387406

We have created an artificial neural network based approach for measuring eye movement using a magnetic contact lens sensing technique. The sensor array is based on using four magnetoresistive sensors. A two-layer feed-forward artificial neural network was used and an artificial eyeball model was made for the test. The neural network is trained with sample data obtained from nine spots. After training, we compared the position calculated from the developed system with the real one. The result shows that there is a good linear relationship between them. This indicates the developed system is capable of recording the position of the eyeball with a high degree of accuracy. © 2005 IEEE.

关键词： Contact lenses

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Unconstrained pulse transit time measurement system for computer users

Unconstrained pulse transit time measurement system for comp...

引用

2005 27th Annual International Conference of the engineering in Medicine and Biology Society, IEEE-EMBS 2005

作者： Park, Juwan Lim, Yongkyu Chee, Youngjoon Kim, Jungsoo Kim, Kokeun Park, Kwang Suk Interdisciplinary Program in Medical and Biological Engineering Seoul National University Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Korea Republic of

ISBN: (纸本)0780387406

Pulse Transit Time (PTT) is a simple non-invasive method to evaluate vascular function using photoplethysmography(PPG) and electrocardiography(ECG). This study introduces unconstrained PTT measurement method for computer users and evaluates that. The proposed system consists of chair and mouse those can measure ECG and PPG respectability. PTT was defined as time delay between ECG R peak and PPG steepest point. The correlation coefficient between PTT that measured from this system and conventional PTT was 0.93. This work will provide many opportunities for ubiquitous health monitoring. ©2005 IEEE.

关键词： Cardiovascular system

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A preliminary study for unconstrained Pulse Arrival Time (PAT) measurement on a chair

A preliminary study for unconstrained Pulse Arrival Time (PA...

引用

2005 27th Annual International Conference of the engineering in Medicine and Biology Society, IEEE-EMBS 2005

作者： Ko, Keun Kim Youngjoon, Chee Juwan, Park Jungsoo, Kim Yong, Kyu Lim Kwang, Suk Park Interdisciplinary Program in Medical and Biological Engineering Seoul National University Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Korea Republic of

ISBN: (纸本)0780387406

A method of measuring the pulse arrival time (PAT) non-consciously on a chair is proposed. In this method, the electrically non-contact ECG measurement system and the air cushion with balancing tubes are used. In this paper, the correlation between the typical PAT and the unconstrained PATs (A-PATs) are compared. The typical PAT is measured as the difference of R-peak of ECG and the steepest descent point of the PPG in toe. The three different A-PATs were measured from the pressure pulse of the air cushion (APP). The correlation between the typical PAT and the A-PAT from the steepest descent point of the APP was the highest (R=0.9663). ©2005 IEEE.

关键词： Electrocardiography

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Common mode noise cancellation for electrically non-contact ECG measurement system on a chair

Common mode noise cancellation for electrically non-contact ...

引用

2005 27th Annual International Conference of the engineering in Medicine and Biology Society, IEEE-EMBS 2005

作者： Ko, Keum Kim Yong, Kyu Lim Kwang, Suk Park Interdisciplinary Program in Medical and Biological Engineering Seoul National University Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Korea Republic of

ISBN: (纸本)0780387406

Electrically non-contact ECG measurement system on a chair can be applied to a number of various fields for continuous health monitoring in daily life. However, the body is floated electrically for this system due to the capacitive electrodes and the floated body is very sensitive to the external noises or motion artifacts which affect the measurement system as the common mode noise. In this paper, the Driven-Seat-Ground circuit similar to the Driven-Right-Leg circuit is proposed to reduce the common mode noise. The analysis of this equivalent circuit is performed and the output signal waveforms are compared between with Driven-Seat-Ground and with capacitive ground. As the results, the Driven-Seat-Ground circuit improves significantly the properties of the fully capacitive ECG measurement system as the negative feedback. © 2005 IEEE.

关键词： Electrocardiography

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Perspective error compensation of pupillography using glint images

Perspective error compensation of pupillography using glint ...

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ETRA 2006 - Symposium on Eye Tracking Research and Applications

作者： Lee, Inbum Park, Kwangsuk Interdisciplinary Program of Medical and Biological Engineering Major Seoul National University Seoul Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Seoul Korea Republic of

ISBN: (纸本)1595933050

This paper suggests a new method to compensate perspective error in measuring real size of pupil of pupillography for pupil light response. To get real size of pupil, the distance between cornea and camera should be calculated. The glints on the eye of the image were used to estimate the distance. The suggested method was validated using telecentric lens. © 2006 ACM.

关键词： Image analysis

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Microfluidic-based PLGA nanosphere generator for protein coating

Microfluidic-based PLGA nanosphere generator for protein coa...

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9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005

作者： Hung, Lung-Hsin Hsieh, Albert Tsung-Hsi Portney, Nate Lee, Abraham Philip Department of Biomedical Engineering Interdisciplinary Materials Science and Engineering Program University of California at Irvine 204 Rockwell Engineering Center Irvine CA 92697 United States Department of Chemical and Environmental Engineering Department University of California at Riverside United States Department of Biomedical Engineering Mechanical and Aerospace Engineering University of California at Irvine United States

ISBN: (纸本)0974361119

This paper presents an integrated microfluidic device for the generation of poly (lactideco- glycolide) (PLGA) nanospheres with protein coating. The chip utilizes the microfluidic droplet reactor technique [1] and PLGA salting-out [2] approach to provide high consistency and efficiency. The size of generated PLGA nanospheres was in the 300nm range;and the coating amount is 1 μg of bovine serum albumin (BSA) per 1mg PLGA nanospheres. Compared to conventional methods, the microfluidic generation of nanospheres reported here has the advantages of continuous synthesis process, tuneable process condition, and small droplet/particle dispersion. Copyright © 2005 by the Transducer Research Foundation, Inc.

关键词： Solvent extraction

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Spatial patterning of fibroblast cells with fabricating holographic patterning on the photoresponsive polymer

Spatial patterning of fibroblast cells with fabricating holo...

引用

2005 27th Annual International Conference of the engineering in Medicine and Biology Society, IEEE-EMBS 2005

作者： Lee, Jae Kyoo Jang, Eunje Lee, Sin-Doo Kim, Sung June Interdisciplinary Program of Biomedical Engineering Seoul National University Seoul Korea Republic of School of Electrical Engineering Seoul National University Seoul Korea Republic of Nano-Bioelectronics and Systems Research Center Seoul National University Seoul Korea Republic of

ISBN: (纸本)0780387406

Micro topographic feature was obtained by laser holographic fabrication on the photoresponsive polymer. Surface feature was localized using photomask for developing two dimensional cellular pattering. Fibroblast cells were cultured and proliferated only on the patterned substrate. Obtained cellular pattering suggests that the laser fabricating with photoresponsive polymer would be applied to regenerating new tissue and developing biomedical device of living cells. © 2005 IEEE.

关键词： Cells

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An wearable energy expenditure analysis system based on the 15-channel whole-body segment acceleration measurement

An wearable energy expenditure analysis system based on the ...

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2005 27th Annual International Conference of the engineering in Medicine and Biology Society, IEEE-EMBS 2005

作者： Yongwon, Jang Jung, M.W. Jaemin, Kang Hee, Chan Kim Interdisciplinary Program Graduate School Seoul National University Seoul Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Seoul Korea Republic of Institute of Medical and Biological Engineering Medical Research Center Seoul National University Seoul Korea Republic of

ISBN: (纸本)0780387406

The measurement of the amount of energy utilized during physical activity has generated considerable interests from various groups ranging from exercise physiologists to nutritionists and fitness center workers. To date, however, the existing energy expenditure estimation methods are not so reliable and compact. In this paper, we propose a new method for accurately and easily estimating energy expenditure during physical activity with a novel algorithm. This method involves acquiring acceleration signals through a 15-channel whole-body segment acceleration measurement system and then estimating the calories expended using a newly developed algorithm. The results of 3 subjects' experiments were compared with a commercially available mask type indirect calorimeter and a 9-axis accelerometry-based calorimeter. The results demonstrate that the proposed method provides a new and reliable way to estimate human energy expenditure during physical activity. © 2005 IEEE.

关键词： Nutrition

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Photo-triggering of the membrane gates in photo-responsive polymer for drug release

Photo-triggering of the membrane gates in photo-responsive p...

引用

2005 27th Annual International Conference of the engineering in Medicine and Biology Society, IEEE-EMBS 2005

作者： Lee, Jae Kyoo Lee, Hoeun Jang, Eunje Lee, Sin-Doo Kim, Sung June Interdisciplinary Program of Biomedical Engineering Seoul National University Seoul Korea Republic of School of Chemical and Biomolecular Engineering Cornell University Ithaca NY School of Electrical Engineering Seoul National University Seoul Korea Republic of Nano-Bioelectronics and Systems Research Center Seoul National University Seoul Korea Republic of

ISBN: (纸本)0780387406

The use of light stimulus for triggering drug is a promising method for accurate drug delivery. A new approach using azopolymer membrane and laser holography was investigated for developing light-triggering drug delivery system. Polymeric drug delivery system was prepared by covering azopolymer membrane on a drug agent. Holographic laser interference generated surface relief grating pattern on the azopolymer surface. The widths and depths of gates on the polymer membrane were easily modified by adjusting incident angle and irradiation time. Ar laser made the polymeric membrane permeable to the drug agent and release it in a solution. This result indicated that the azopolymer and laser holography would provide a strong foundation for the light-triggering drug delivery system. © 2005 IEEE.

关键词： Biological membranes

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Sleep apnea detection by slope analysis

Sleep apnea detection by slope analysis

引用

3rd IASTED International Conference on Medical engineering 2005

作者： Han, Jonghee Shin, Hongbeom Jeong, Do-Un Park, Kwangsuk Department of Biomedical Engineering College of Medicine and Hospital Seoul National University Seoul Korea Republic of Interdisciplinary Program College of Medicine and Hospital Seoul National University Seoul Korea Republic of Department of Psychiatry and Behavioral Science College of Medicine and Hospital Seoul National University Seoul Korea Republic of

ISBN: (纸本)0889864780

Detection of sleep apnea is the one of the major tasks in sleep medicine. Various methods have been applied to detect sleep apnea by analyzing different bio-signals. This paper introduces an innovative algorithm that analyze slope of nasal airflow signal in polysomnography. In this study, slope is obtained by the moving average of an absolute differentiation of a signal with 3.8 seconds' time window followed by segmentation of 1 second. Apnea threshold is determined by 10% of the slope of normal breathing. If segments having slope below apnea threshold appear for 10 consecutive segments, those segments are marked as apnea. The presented algorithm analyzed polysomnography records from 13 subjects and detected 2500 apnea events. Performance of presented algorithm was evaluated by comparing its results against the sleep specialist's manual scoring on same records. The overall agreement rate between the two was 95.36% (κ=0.86). In considering its simplicity and lower computational load, the presented algorithm is robust and useful.

关键词： Sleep research

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