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Variable Length Multi-Objective Whale Optimization for Trust Aware Data Gathering in Wireless Sensor Network

IEEE Access 2025年 13卷 32100-32121页

作者： Saad, Mohammed Ayad Jaafar, Rosmina Chellappan, Kalaivani Faculty of Engineering and Built Environment Department of Electrical Electronics and System Engineering Selangor Bangi43600 Malaysia Al-Kitab University Department of Medical Instrumentations Technique Engineering Kirkuk36001 Iraq Universitas Airlangga Biomedical Engineering Study Program Faculty of Science and Technology Surabaya60115 Indonesia

Efficient data collection in wireless sensor networks (WSNs) is crucial. While traditional approaches rely on stationary data sinks, the use of mobile sinks, like unmanned aerial vehicles (UAVs), has shown promise in enhancing data-gathering capabilities. However, existing methods often overlook the importance of trust, leaving the network susceptible to malicious or faulty nodes. To address this issue, we propose a novel trust-aware data-gathering algorithm, Variable Length Multi-Objective Whale Optimization Data Gathering (VLMOWO-DG). Our algorithm simultaneously optimizes energy consumption, delay, and trust while employing mobile sinks to collect data from sensor nodes. By considering trust as a key performance metric, we improve data reliability and security. The VLMOWO-DG algorithm introduces flexibility through variable-length solution representation and application-oriented operators, allowing for efficient exploration of the solution space. Simulation results demonstrate that our proposed algorithm significantly outperforms established benchmarks, NSGA-II and NSGA-III, in terms of domination and hypervolume. This leads to a remarkable improvement of 200% in data gathering performance. © 2015 The Authors.

关键词： Data collection

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A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair

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Neural Regeneration Research 2025年第1期20卷 291-304页

作者： Simeon C.Daeschler Katelyn J.W.So Konstantin Feinberg Marina Manoraj Jenny Cheung Jennifer Zhang Kaveh Mirmoeini JPaul Santerre Tessa Gordon Gregory HBorschel SickKids Research Institute Neuroscience and Mental Health ProgramTorontoONCanada Institute of Biomaterials and Biomedical Engineering University of TorontoTorontoONCanada Indiana University School of Medicine IndianapolisINUSA Division of Plastic and Reconstructive Surgery the Hospital for Sick ChildrenTorontoONCanada Translational Biology and Engineering Program Ted Rogers Centre for Heart ResearchInstitute of Biomedical EngineeringFaculty of DentistryUniversity of TorontoTorontoONCanada

Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong ***,there are no FDA-approved therapies available to promote nerve *** accelerates axonal regeneration,but systemic side effects presently outweigh its potential benefits for peripheral nerve *** authors describe herein a biodegradable polyurethane-based drug delivery system for the sustained local release of tacrolimus at the nerve repair site,with suitable properties for scalable production and clinical application,aiming to promote nerve regeneration and functional recovery with minimal systemic drug *** is encapsulated into co-axially electrospun polycarbonate-urethane nanofibers to generate an implantable nerve wrap that releases therapeutic doses of bioactive tacrolimus over 31 *** and drug loading are adjustable for applications in small and large caliber nerves,and the wrap degrades within 120 days into biocompatible *** released from the nerve wrap promotes axon elongation in vitro and accelerates nerve regeneration and functional recovery in preclinical nerve repair models while off-target systemic drug exposure is reduced by 80%compared with systemic *** its surgical suitability and preclinical efficacy and safety,this system may provide a readily translatable approach to support axonal regeneration and recovery in patients undergoing nerve surgery.

关键词： biodegradable local drug delivery nerve injury nerve regeneration nerve wrap tacrolimus

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Nanoparticle formulation of ZnO: TiO2 as sunscreen cream for Cutaneous Lupus Erythematosus (CLE) patients 12

Nanoparticle formulation of ZnO: TiO2 as sunscreen cream for...

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12th International Conference on Physics and Its Applications, ICOPIA 2024

作者： Siswanto Qulub, Fitriyatul Junico, Vallery Ofelia Viannco Physics Program Study Faculty Science and Technology Universitas Airlangga Surabaya Indonesia Biomedical Engineering Program Study Faculty Science and Technology Universitas Airlangga Surabaya Indonesia

Cutaneous Lupus Erythematosus (CLE) is a form of lupus that affects the skin and is highly sensitive to ultraviolet (UV) light. UV-B. in particular. can trigger inflammation and apoptosis in CLE patients. making a sunscreen with effective UVB protection crucial. This study evaluates the effectiveness of zinc oxide (ZnO) and titanium dioxide (TiO2) nanoparticles in sunscreen. ZnO and TiO2 nanoparticles were prepared using the High Energy Milling method. resulting in particle sizes of 7.77 nm and 4.44 nm. respectively. The creams containing these nanoparticles were tested for physical stability and UV protection. Results showed that the creams were physically stable and provided good UV protection. with ZnO and TiO2 nanoparticles making up 12.60% of the total cream ingredients. resulting in the highest SPF (Sun Protection Factor) value of 62.0 ± 1.37. © 2025 Institute of Physics Publishing. All rights reserved.

关键词： TiO2 nanoparticles

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Brain age estimation:premise,promise,and problems

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Neural Regeneration Research 2025年第8期20卷 2313-2314页

作者： Jarrad Perron Ji Hyun Ko Graduate Program in Biomedical Engineering Price Faculty of EngineeringUniversity of ManitobaWinnipegMBCanada PrairieNeuro Research Centre Kleysen Institute for Advanced MedicineHealth Sciences CentreWinnipegMBCanada Department of Human Anatomy and Cell Science Rady Faculty of Health SciencesUniversity of ManitobaWinnipegMBCanada

Premise:The com bined effects of modern healthcare practices which prolong lifespan and declining birthrates have created unprecedented changes in age demographics worldwide that are especially pronounced in Japan,South Korea,Europe,and North *** old age is the most significant predictor of dementia,global healthcare systems must rise to the challenge of providing care for those with neurodegenerative disorders.

关键词： estimation providing birth

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A generalized adder for cell size homeostasis: Effects on stochastic clonal proliferation

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Biophysical Journal 2025年第9期124卷 1376-1386页

作者： Nieto, César Vargas-García, César Augusto Singh, Abhyudai Department of Electrical and Computer Engineering University of Delaware Newark DE United States AGROSAVIA - Corporacion Colombiana de Investigacion Agropecuaria Cundinamarca Mosquera Colombia Department of Electrical and Computer Engineering Biomedical Engineering Mathematical Sciences Interdisciplinary Neuroscience Program University of Delaware Newark DE United States

Measurements of cell size dynamics have revealed phenomenological principles by which individual cells control their size across diverse organisms. One of the emerging paradigms of cell size homeostasis is the adder, where the cell cycle duration is established such that the cell size increase from birth to division is independent of the newborn cell size. We provide a mechanistic formulation of the adder, considering that cell size follows any arbitrary nonexponential growth law. Our results show that the main requirement to obtain an adder regardless of the growth law (the time derivative of cell size) is that cell cycle regulators are produced at a rate proportional to the growth law, and cell division is triggered when these molecules reach a prescribed threshold level. Among the implications of this generalized adder, we investigate fluctuations in the proliferation of single-cell-derived colonies. Considering exponential cell size growth, random fluctuations in clonal size show a transient increase and then eventually decay to zero over time (i.e., clonal populations become asymptotically more similar). In contrast, several forms of nonexponential cell size dynamics (with adder-based cell size control) yield qualitatively different results: clonal size fluctuations monotonically increase over time, reaching a nonzero value. These results characterize the interplay between cell size homeostasis at the single-cell level and clonal proliferation at the population level, explaining the broad fluctuations in clonal sizes seen in barcoded human cell lines. © 2025 Biophysical Society

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Synthesis, characterization, and interfacial adhesion of titania iodine-doped nanotubes architectures on additively manufactured Ti-6Al-4 V implant

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Materialwissenschaft und Werkstofftechnik 2025年第3期56卷 438-454页

作者： Taweekitikul, P. Aliyu, A.A. Decha-Umphai, D. Tantavisut, S. Khamwannah, J. Puncreobutr, C. Lohwongwatana, B. Biomedical Engineering Program Faculty of Engineering Chulalongkorn University Bangkok10330 Thailand Trauma Unit Department of Orthopaedic Queen Savang Vadhana Memorial Hospital Chonburi20110 Thailand Biomedical Engineering Research Center Chulalongkorn University Bangkok10330 Thailand M3D Laboratory Advanced Materials Analysis Research Unit Department of Metallurgical Engineering Faculty of Engineering Chulalongkorn University Phayathai Road Wangmai Pathumwan District Bangkok10330 Thailand Biomechanics Research Center Meticuly Co. Ltd. Chulalongkorn University Bangkok10330 Thailand Hip Fracture Research Unit Department of Orthopaedic Faculty of Medicine Chulalongkorn University Bangkok10330 Thailand Department of Metallurgical Engineering Faculty of Engineering Chulalongkorn University Bangkok10330 Thailand CambridgeMA02139 United States

This study aimed to synthesize, characterize, and evaluate the adhesion strength of titania nanotubes (titania nanotubes) and iodine-doped titania nanotubes (I-titania nanotubes) architectures on the additively manufactured Ti-6Al-4 V (Ti64) implant surface. The titania nanotubes and I-titania nanotubes were synthesized through two stages of electrochemical anodization, whereby titania nanotubes are anodically fabricated through a conventional approach and then modified by replacing the ethylene glycol electrolyte with potassium iodide solution. The characterization results revealed the formation of α-Ti, β-Ti, and titanium iodide (TiI2) phases on the titania nanotubes and I-titania nanotubes surfaces. The morphology of titania nanotubes exhibits a consistent diameter, evenly distributed, well-ordered array, and densely packed nanotubular structures. Formation of a water-soluble fluoride-rich [TiF6]2 complexes in the inner titania nanotubes surface and incessant nanotube′s sidewall etching resulted in poor interfacial titania nanotubes adhesion to the titanium-substrate surface. Iodine doping on the titania nanotubes is believed to reduce the [TiF6]2 complexes accumulation and the titania nanotubes sidewall etching. This facilitates the adhesion and interfacial mechanical anchorage between the titania nanotubes and the surface of the Ti64 implant. The hardness and adhesion strength of the titania nanotubes increased by more than 50 %, due to the formation of a hard titanium iodide film at the titania nanotubes/I-titania nanotubes surfaces and interfaces. © 2025 The Author(s). Materialwissenschaft und Werkstofftechnik published by Wiley-VCH GmbH.

关键词： Potassium iodide

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Injectable Platelet Lysate–Thai Silk Fibroin Hydrogel for Canine Intervertebral Disc Repair: A Minimally Invasive Strategy for Sustained Growth Factor Release

SSRN

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SSRN 2025年

作者： Ratanavaraporn, Juthamas Chayatup, Kannika Boonkruephan, Sarinthorn Keeratihattayakorn, Saran Wangdee, Chalika Interdisciplinary Program of Biomedical Engineering Program Faculty of Engineering Chulalongkorn University Bangkok Thailand Biomedical Engineering Research Center Faculty of Engineering Chulalongkorn University Bangkok Thailand Research Unit Chulalongkorn University Bangkok10330 Thailand Department of Veterinary Surgery Faculty of Veterinary Science Chulalongkorn University Bangkok Thailand

Canine intervertebral disc degeneration (IVDD) is a progressive spinal disorder that compromises mobility, induces chronic pain, and reduces quality of life. Existing treatments provide only symptomatic relief and do not halt disease progression or restore disc integrity. This study aims to develop and characterize an injectable platelet lysate–Thai silk fibroin (PL–TSF) hydrogel as a minimally invasive platform for localized and sustained growth factor delivery in canine IVDD treatment. The hydrogel was formulated using PL from expired canine platelet concentrates and TSF extracted from cocoons of Thai-bred Bombyx mori silkworms. Fabricated via sonication-induced gelation, it exhibited tunable gelation kinetics and injectability through a 27-gauge spinal needle, supporting clinical feasibility for minimally invasive delivery. PL incorporation enhanced the hydrogel’s elasticity and mechanical resilience without compromising scaffold integrity. The system demonstrated biphasic degradation over 35 days. TGF-β1 release kinetics exhibited an initial burst followed by sustained release over 28 days, consistent with diffusion-controlled delivery suitable for IVD repair. Cytotoxicity testing confirmed good biocompatibility and supported the viability of canine chondrocytes. By combining mechanical support with prolonged growth factor availability, PL–TSF hydrogels address key limitations of conventional platelet-based therapies and represent a promising strategy for early-stage IVDD intervention. Further in vivo studies are warranted to confirm long-term regenerative efficacy and facilitate clinical translation in veterinary medicine. © 2025, The Authors. All rights reserved.

关键词： Gelation

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Innovative metallization pattern and technique for industrial rear emitter p-type tunnel oxide passivated contact solar cells

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Journal of Industrial and engineering Chemistry 2025年 147卷 628-635页

作者： Khokhar, Muhammad Quddamah Yousuf, Hasnain Rahman, Rafi Ur Aida, Maha Nur Madara, Polgampola Chamani Jony, Jaljalalul Abedin Dao, Vinh-Ai Pham, Duy Phong Yi, Junsin Department of Electrical and Computer Engineering Sungkyunkwan University Suwon16419 Korea Republic of Interdisciplinary Program in Photovoltaic System Engineering Sungkyunkwan University Suwon16419 Korea Republic of Department of Future Energy Engineering Sungkyunkwan University Suwon16419 Korea Republic of Department of Physics Faculty of Applied Sciences HCMC University of Technology and Education Ho Chi Minh City700000 Viet Nam College of Information and Communication Engineering Sungkyunkwan University Suwon16419 Korea Republic of

In this study, we aim to enhance the efficiency of p-type tunnel oxide passivated contact (p-TOPCon) solar cells by improving charge carrier extraction while achieving higher fill factor (FF) and open circuit voltage (Voc). We explore various potential methods for the photovoltaic industrial procedure, including optimizing metallization patterns and techniques, such as the utilization of a high efficiency grid pattern (HEGP) in place of the conventional straight finger-line pattern (SFLP). Co-firing conditions, peak firing temperature, and belt speed are investigated for their impact on FF enhancement, along with evaluating the effects of single and double print processes. Furthermore, we examine the efficacy of Nafion treatment as a surface modification technique to enhance FF. Experimental results indicate that optimizing co-firing conditions and employing Nafion treatment significantly increased FF to approximately 83.26% in p-TOPCon solar cells. Adjusting peak firing temperature and belt speed, as well as implementing the double print process, demonstrate superior FF enhancement compared to the single print process. Additionally, Nafion treatment contributes to FF improvement by passivating surface defects and enhancing charge carrier collection. Overall, this study provides valuable insights into optimizing co-firing conditions and surface treatment techniques to enhance p-TOPCon solar cell efficiency (Eff) up to 23.50%, thus advancing high-efficiency photovoltaic technology. © 2024 The Korean Society of Industrial and engineering Chemistry

关键词： Metallizing

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Investigation of Microplastic Abundance from Commercial Marine Fish in Bintulu, Sarawak, Malaysia

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Water, Air, and Soil Pollution 2025年第7期236卷 1-14页

作者： Son Sam, Wil Rubiyatno Hadibarata, Tony Environmental Engineering Program Curtin University CDT250 Miri98009 Malaysia Graduate Faculty of Interdisciplinary Research University of Yamanashi 4-3-11 Takeda Yamanashi Kofu400-8511 Japan

The plastic pollution is an ever-growing issue across the globe. In particular, Microplastics (MPs) can act as toxin accumulators in the fish tissues, which may transfer to human bodies via food chain and potentially harmful to human health. In Malaysia, studies related to MPs mostly focused on sediment and wild-caught freshwater fish. However, there is a lack of study on commercial marine fish especially conducted in Bintulu, Sarawak, East Malaysia. Therefore, this study was to investigate and establish baseline data for future research and monitor of MPs pollution in Bintulu's marine environment. The MPs were observed in the gastrointestinal tracts (GITs) and gills from the 6 species of commercial marine fish. The sample was digested with 15% of KOH solution, with shaking at 90 rpm, at 60 °C for 24 h, then continued with shaking at 90 rpm at room temperature for 24 h. After that, the MPs sample were extracted by density separation using 100 mL NaCl solution. The samples were identified and characterized under stereomicroscope and Attenuated Total Reflection Fourier Transform Infrared spectroscopy (ATR-FTIR). As the result, the highest abundance was found in Alepes djedaba with an abundance of 3.51 ± 0.764 items/g, and the lowest abundance was found in Gerres filamentosus with an abundance of 1.48 ± 0.440 items/g. The most dominant shape, color and size of MPs across the study were fiber (73%), blue (47%) and less than 1 mm (67%), respectively. FTIR analysis detected polymer compositions of polystyrene (PS) and polyamide (PA) in the sample. This study provides baseline data on MPs research in Bintulu and becomes source of information for policy makers to take better actions. © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2025.

关键词： Fourier transform infrared spectroscopy

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Low resolution fabrication of highly precise diffractive optics by near index matching 18

Low resolution fabrication of highly precise diffractive opt...

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Advanced Fabrication Technologies for Micro/Nano Optics and Photonics XVIII 2025

作者： Kedem, Reut Orange Leites, Leonid Shechtman, Yoav Russell Berrie Nanotechnology Institute Technion—Israel Institute of Technology Haifa Israel Lorry Lokey Interdisciplinary Center for Life Sciences and Engineering Technion—Israel Institute of Technology Haifa Israel Faculty of Biomedical Engineering Technion—Israel Institute of Technology Haifa Israel Faculty of Electrical and Computer Engineering Technion—Israel Institute of Technology Haifa Israel

ISBN: (数字)9781510685116

ISBN: (纸本)9781510685109

Diffractive optical elements (DOEs) are essential in optics and photonics, offering compact solutions for complex wavefront shaping. Despite their potential, the widespread adoption of DOEs remains constrained by the high costs and complexities of current fabrication techniques. This study introduces a simple, cost-effective method for fabricating high-performance, solid DOEs by conjugating two nearly index-matched transparent materials. This approach leverages commercially available additive manufacturing (AM) to produce templates at a resolution of tens of micrometers, enabling substantial scaling in the axial dimension, dramatically simplifying fabrication. The method's versatility is demonstrated through the production of microlens arrays, vortex plates, and phase masks for three-dimensional localization microscopy. Additionally, it facilitates the fabrication of highly complex elements, such as high-order spiral phase plates and spectrum-encoding phase masks, significantly expanding the accessibility and applicability of DOEs. © 2025 SPIE.

关键词： Diffractive optical elements

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