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biomedical engineering International Conference (BMEiCON)

作者： Piyamas Suapang Chadaporn Naruephai Methinee Thongyoun Sorawat Chivaprecha Biomedical Instrumentation Program Department of Physics Faculty of Sciences Rangsit University Pathumthani Thailand Department of Telecommunications Engineering Engineering Faculty King Mongkut's University of Technology Bangkok Thailand

Medical images segmentation is an important work for object recognition of the human organs and it is an important pre-processing step in medical image segmentation and 3D reconstruction. Conventionally, segmentation is detected according to some early brought forward algorithms such as gradient-based algorithm and template-based algorithm, but they are not so good for noise medical image segmentation. In this paper, basic morphological theory and operations are introduced at first, and then a novel morphological segmentation algorithm is proposed to detect the segment of mammographic masses with salt-and-pepper noise. The experimental results show that the proposed algorithm is more efficient for medical image denoising and segmentation than the usually used template-based segmentation algorithms and general morphological segmentation algorithms.

关键词： Image segmentation Image edge detection Morphology Noise biomedical imaging Algorithm design and analysis Detectors

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A Mammography Database and Viewer System

A Mammography Database and Viewer System

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biomedical engineering International Conference (BMEiCON)

作者： Piyamas Suapang Methinee Thongyoun Rodjarin Boontawan Sorawat Chivaprecha Biomedical Instrumentation Program Department of Physics Faculty of Sciences Rangsit University Pathumthani Thailand Department of Telecommunications Engineering Engineering Faculty King Mongkut's Institute of Technology Ladkrabang Bangkok Thailand

ISBN: (纸本)9781467348904

A Mammography Database and Viewer System have collected and stored mammography images of Thai women, treated at the Radiology Department of Hospital in Rangsit, Pathumtani, Thailand, constructed a database using the digitized mammography images, and developed an image viewing system to display these digital mammograms. The images are stored with the high resolution Matrox Morphis (MOR/2VD/84*) frame grabber board. The digital mammography database is powered by MySQL and PHP. It also has a web-based search engine (with secure access) so that the information can be made accessible to all medical team members. The image viewing software, DICOM Viewer, is coded in Borland C++ Builder and is intended to help medical professionals view and retrieve large data sets in near real time. This have already digitized 200 cases (one case per patient, twenty to forty images per case). The system also have developed a MySQL-based image database, and a PHP-based web-search engine to retrieve cases that have masses (benign or malignant) or calcifications (benign or malignant). This database has been evaluated by medical professionals and the experimental results obtained so far are very promising (high image qualities, fast access time). The system are currently developing an image content-based retrieval function for the database system in order to provide improved search capability for the medical professionals.

关键词： Databases DICOM Software Breast cancer Educational institutions

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Heart sounds measurement using PVDF film sensor and their comparison with RR intervals of ECG signals

Heart sounds measurement using PVDF film sensor and their co...

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IEEE EMBS International Conference on Information Technology Applications in Biomedicine (ITAB)

作者： Won Kyu Lee Gih Sung Chung Hyun Jae Baek Kwang Suk Park Interdisciplinary Program for Bioengineering Seoul National University Seoul South Korea Department of Biomedical Engineering College of Medicine Seoul National University Seoul South Korea

Heart sounds are generated by the fluctuations of blood velocity and the vibrations of cardiac structure. The auscultation of heart sounds is one of the basic tools for patient diagnosis and provides a lot of information associated with cardiovascular systems. For converting mechanical sound waves into electronic signals, PVDF (polyvinylidene fluoride) film sensor was used as heart sounds measurement device. After suited filtering process, the first (S1) and the second (S2) heart sounds components were plainly distinguished and their peak timings were closely corresponded to reference heart sounds signals measured by microphone. Lastly, there was high correlation between S1 intervals (from PVDF signals) and RR intervals (from ECG signals). So it is expected that S1 intervals can replace RR intervals. In future application, these methods have possibilities for non-intrusive heart rate estimation.

关键词： Heart Electrocardiography Films Mechanical variables measurement Filtering Correlation Timing

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Corrigendum to “Navigating the site for embryo implantation: Biomechanical and molecular regulation of intrauterine embryo distribution” [Molecular Aspects of Medicine 34 (2013) 1024–1042]

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Molecular Aspects of Medicine 2013年第6期34卷 1257-1257页

作者： Qi Chen Ying Zhang David Elad Ariel J. Jaffa Yujing Cao Xiaoqin Ye Enkui Duan State Key Laboratory of Reproductive Biology Institute of Zoology Chinese Academy of Sciences Beijing 100101 China Department of Biomedical Engineering Faculty of Engineering Tel-Aviv University Tel-Aviv 69978 Israel Ultrasound Unit in Obstetrics and Gynecology Lis Maternity Hospital Tel-Aviv Medical Center Tel-Aviv 64239 and Sackler Faculty of Medicine Tel-Aviv University Tel-Aviv 69978 Israel Department of Physiology and Pharmacology College of Veterinary Medicine & Interdisciplinary Toxicology Program The University of Georgia Athens GA 30602 USA

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Heart sounds measurement using PVDF film sensor and their comparison with RR intervals of ECG signals

Heart sounds measurement using PVDF film sensor and their co...

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IEEE-EMBS International Conference on biomedical and Health Informatics, BHI 2012. In Conj. with the 8th Int. Symp.on Medical Devices and Biosensors and the 7th Int. Symp. on biomedical and Health engineering

作者： Lee, Won Kyu Chung, Gih Sung Baek, Hyun Jae Park, Kwang Suk Interdisciplinary Program for Bioengineering Seoul National University 111 Fundamental Medical Research Building I 101 Daehak-ro Jongno-gu Seoul Korea Republic of Interdisciplinary Program for Bioengineering Seoul National University 713 Fundamental Medical Research Building I 101 Daehak-ro Jongno-gu Seoul Korea Republic of Interdisciplinary Program for Bioengineering Seoul National University 807 Fundamental Medical Research Building I 101 Daehak-ro Jongno-gu Seoul Korea Republic of Department of Biomedical Engineering Seoul National University College of Medicine 103 Daehak-ro Jongno-gu Seoul Korea Republic of

ISBN: (纸本)9781457721779

关键词： Heart

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31st Annual Meeting and Associated programs of the Society for Immunotherapy of Cancer (SITC 2016): part one: National Harbor, MD, USA. 9-13 November 2016

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J Immunother Cancer 2016年第SUPPL 1期4卷 1-1页

作者： Andreas Lundqvist Vincent van Hoef Xiaonan Zhang Erik Wennerberg Julie Lorent Kristina Witt Laia Masvidal Sanz Shuo Liang Shannon Murray Ola Larsson Rolf Kiessling Yumeng Mao John-William Sidhom Catherine A. Bessell Jonathan Havel Jonathan Schneck Timothy A. Chan Eliot Sachsenmeier David Woods Anders Berglund Rupal Ramakrishnan Andressa Sodre Jeffrey Weber Roberta Zappasodi Yanyun Li Jingjing Qi Philip Wong Cynthia Sirard Michael Postow Walter Newman Henry Koon Vamsidhar Velcheti Margaret K. Callahan Jedd D. Wolchok Taha Merghoub Lawrence G. Lum Minsig Choi Archana Thakur Abhinav Deol Gregory Dyson Anthony Shields Cara Haymaker Marc Uemura Ravi Murthy Marihella James Daqing Wang Julie Brevard Catherine Monaghan Suzanne Swann James Geib Mark Cornfeld Srinivas Chunduru Sudhir Agrawal Cassian Yee Jennifer Wargo Sapna P. Patel Rodabe Amaria Hussein Tawbi Isabella Glitza Scott Woodman Wen-Jen Hwu Michael A. Davies Patrick Hwu Willem W. Overwijk Chantale Bernatchez Adi Diab Erminia Massarelli Neil H. Segal Vincent Ribrag Ignacio Melero Tara C. Gangadhar Walter Urba Dirk Schadendorf Robert L. Ferris Roch Houot Franck Morschhauser Theodore Logan Jason J. Luke William Sharfman Fabrice Barlesi Patrick A. Ott Laura Mansi Shivaani Kummar Gilles Salles Cecilia Carpio Roland Meier Suba Krishnan Dan McDonald Matthew Maurer Xuemin Gu Jaclyn Neely Satyendra Suryawanshi Ronald Levy Nikhil Khushalani Jennifer Wu Jinyu Zhang Fahmin Basher Mark Rubinstein Mark Bucsek Guanxi Qiao Cameron MacDonald Bonnie Hylander Elizabeth Repasky Shilpak Chatterjee Anusara Daenthanasanmak Paramita Chakraborty Kyle Toth Megan Meek Elizabeth Garrett-Mayer Michael Nishimura Chrystal Paulos Craig Beeson Xuezhong Yu Shikhar Mehrotra Fei Zhao Kathy Evans Christine Xiao Alisha Holtzhausen Brent A. Hanks Nicole Scharping Ashley V. Menk Rebecca Moreci Ryan Whetstone Rebekah Dadey Simon Watkins Robert Ferris Greg M. Delgoffe Jonathan Peled Sean Devlin Anna Staffas Melissa Lumish Kori Porosnicu Rodriguez Katya Ahr Miguel Perales Sergio Giralt Ying Taur Eric Pam Karolinska Institutet Stockholm Stockholms Lan Sweden Weill Cornell Medical College New York NY USA Nova Southeastern University Cell Therapy Institute Fort Lauderdale FL USA Johns Hopkins University School of Medicine Baltimore MD USA Immunology Program Johns Hopkins University School of Medicine Columbia MD USA Memorial Sloan Kettering Cancer Center New York NY USA Johns Hopkins Medical Institute Baltimore MD USA University of Rochester Monrovia MD USA NYU Langone Medical Center New York NY USA H. Lee Moffitt Cancer Center Tampa FL USA Ludwig Collaborative Laboratory Memorial Sloan Kettering Cancer Center New York NY USA Immune Monitoring Core Facility Memorial Sloan Kettering Cancer Center New York NY USA Leap Therapeutics Cambridge MA USA Department of Medicine Memorial Sloan Kettering Cancer Center New York NY USA Case Western Reserve University Cleveland OH USA Cleveland Clinic Main Campus Cleveland OH USA University of Virginia Cancer Center Charlottesville VA USA Stony Brook University Medical Center Stony Brook NY USA Karmanos Cancer Institute Detroit MI USA University of Texas MD Anderson Cancer Center Houston TX USA Idera Pharmaceuticals Inc. Cambridge MA USA Institut Gustave Roussy Villejuif Ile-de-France France Center for Applied Medical Research (CIMA) University of Navarra Pamplona Navarra Spain University of Pennsylvania Philadelphia PA USA Earle A. Chiles Research Institute Providence Cancer Center Portland OR USA Universitätsklinikum Essen Essen Nordrhein-Westfalen Germany University of Pittsburgh Pittsburgh PA USA CHU Rennes Service Hématologie Clinique and INSERM 0203 Unité d’Investigation Clinique Rennes Bretagne France Centre Hospitalier Régional Universitaire de Lille Lille Nord-Pas-de-Calais France Simon Cancer Center Indiana University Indianapolis IN USA University of Chicago School of Medicine Chicago IL USA Johns Hopkins University School of Medicine Lutherville MD USA Multidisciplinary Oncology and Therapeuti

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Validation of heart rate extraction using video imaging on a built-in camera system of a smartphone

Validation of heart rate extraction using video imaging on a...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Sungjun Kwon Hyunseok Kim Kwang Suk Park Interdisciplinary Program of Bioengineering Seoul National University Seoul 110 799 Korea Department of Biomedical Engineering College of Medicine Seoul National University Seoul 110 799 Korea

ISBN: (纸本)9781424441198

As a smartphone is becoming very popular and its performance is being improved fast, a smartphone shows its potential as a low-cost physiological measurement solution which is accurate and can be used beyond the clinical environment. Because cardiac pulse leads the subtle color change of a skin, a pulsatile signal which can be described as photoplethysmographic (PPG) signal can be measured through recording facial video using a digital camera. In this paper, we explore the potential that the reliable heart rate can be measured remotely by the facial video recorded using smartphone camera. First, using the front facing-camera of a smartphone, facial video was recorded. We detected facial region on the image of each frame using face detection, and yielded the raw trace signal from the green channel of the image. To extract more accurate cardiac pulse signal, we applied independent component analysis (ICA) to the raw trace signal. The heart rate was extracted using frequency analysis of the raw trace signal and the analyzed signal from ICA. The accuracy of the estimated heart rate was evaluated by comparing with the heart rate from reference electrocardiogram (ECG) signal. Finally, we developed FaceBEAT, an iPhone application for remote heart rate measurement, based on this study.

关键词： smartphone becoming measurement

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Estimation of sleep onset latency based on the correlation between blood pressure and heart beat interval

Estimation of sleep onset latency based on the correlation b...

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IEEE EMBS International Conference on Information Technology Applications in Biomedicine (ITAB)

作者： Da Woon Jung Gih Sung Chung Su Hwan Hwang Kwang Suk Park Interdisciplinary Program of Bioengineering Graduate School Seoul National University Seoul South Korea Department of Biomedical Engineering College of Medicine Seoul National University Seoul South Korea

Sleep onset latency (SOL) provides an objective assessment of sleepiness and it also clinically useful as a sleep deprivation diagnostic tool. In this study, we suggest a new approach to estimate SOL based on the correlation between blood pressure (BP) and heart beat interval (HBI). This approach facilitates less intrusive finding of SOL as compared with currently using polysomnographic method. We hypothesized that the arterial baroreflex, one kind of reflex mechanism to regulate BP, takes a role of maintaining sleep's toning-down effect on BP. At the time of transition from full wakefulness to sleep, the toning-down effect starts to drop the BP and the arterial baroreflex is activated to maintain lowered BP by leading to increase in HBI for the elevated BP. Consequently, there is a great contribution of arterial baroreflex to HBI control. With a quantitative evaluation of the contribution, we tried to estimate SOL. For six healthy subjects (27.5 ± 3.15 years), the mean absolute error (MAE) was 0.3 ± 0.42 minutes. We expect our method can be applicable to non-intrusive and automatic SOL estimation system by not using electroencephalogram (EEG) sensors.

关键词： Sleep Lead Medical diagnostic imaging Protocols Electrocardiography Position measurement Weight measurement

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Heat transfer efficiency analysis of infant radiant warmer by 3D finite element method

Heat transfer efficiency analysis of infant radiant warmer b...

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biomedical engineering International Conference (BMEiCON)

作者： K. Roongprasert P. Phasukkit S. Airphaiboon C. Pintavirooj N. Thongpance A. Sanpanich Biomedical Engineering Program Rangsit University Bangkok Thailand Faculty of Engineering King Mongkut's Institute of Technology Ladkrabang Bangkok Thailand Institute of Molecular Biosciences Mahidol University Bangkok Thailand

ISBN: (纸本)9781467348904

This paper presents heat transfer from infrared element source from infant radiant warmer. The principles of thermal radiate using three-dimensional finite element methods is show the efficiency and effect of Infant radiant warmer. In the design of the system has to model the underlying reality of the infant radiant warmer are used for Simulation results were similar to reality as possible. The simulation results of thermal radiation from the infrared lamp to mattress by using the three-dimensional finite element methods simulation as close to the true result. The results come in the form of temperature, temperature gradient and the direction of heat radiation into the mattress. The result can be that the effects of radiation on the skin of newborns using infant radiant warmer treatment. The results of the analysis of the principle of three-dimensional finite element methods then try to make it easy to design infant radiant warmer effective for use with newborns up.

关键词： Heating Pediatrics Finite element methods Solid modeling Heat transfer Atmospheric modeling Educational institutions

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Distinct mechanisms of FAK mechanoactivation by different extracellular matrix proteins

Distinct mechanisms of FAK mechanoactivation by different ex...

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第五届中美生物医学工程暨海内外生物力学学术研讨会

作者： Jihye Seong Arash Tajik Jie Sun Jun-Lin Guan Martin J.Humphries Susan E.Craig Asha Shekaran Andres J.Garcia Ning Wang Yingxiao Wang Neuroscience Program University of IllinoisUrbana-ChampaignUrbanaIL61801USA Department of Mechanical Science and Engineering University of IllinoisUrbana-ChampaignUrbanaIL61801USA Department of Bioengineering & Beckman Institute for Advanced Science and Technology University of IllinoisUrbana-ChampaignUrbanaIL61801USA Division of Molecular Medicine and Genetics Departments of Internal Medicine and Cell & Developmental BiologyUniversity of Michigan Medical SchoolAnn ArborMI48109USA Wellcome Trust Centre for Cell-Matrix Research Faculty of Life SciencesUniversity of ManchesterManchesterUK Woodruff School of Mechanical Engineering and Petit Institute for Bioengineering and Bioscience Georgia Institute of TechnologyAtlantaGA30332USA Department of Biomedical Engineering School of Life Science and TechnologyHuazhong University of Science and Technology Department of Integrative and Molecular Physiology Center for Biophysics and Computational BiologyInstitute for Genomic BiologyUniversity of IllinoisUrbana-ChampaignUrbanaIL61801USA Department of Bioengineering University of CaliforniaSan DiegoCA92093USA

Introduction Cells can sense and respond to the mechanical microenvironment by converting forces into biochemical signals inside the cells,*** adhesions are the major sites of interaction between a cell and its extracellular matrix(ECM) microenvironment, thus outside mechanical signals can be sensed at focal adhesions through transmembrane receptor *** particular,it has been shown that matrix elasticity can control the cell fate

关键词： FAK Distinct mechanisms of FAK mechanoactivation by different extracellular matrix proteins ECM

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