检索结果-内蒙古大学图书馆

An approach of reducing measure time of noninvasive thermometer: Application of curve-fitting method and autoregressive model for reducing the measure time of dual-heat-flux thermometer

An approach of reducing measure time of noninvasive thermome...

引用

作者： Sim, S.Y. Baek, H.J. Chung, G.S. Park, K.S. Interdisciplinary Program of Bioengineering Seoul National University Jongnogu Seoul Korea Republic of Department of Biomedical Engineering College of Medicine Seoul National University Jongnogu Seoul Korea Republic of

ISBN: (纸本)9789898425355

Newly developed dual-heat-flux thermometer is expected to be useful in measuring core body temperature noninvasively. However, as it takes more than 30 min to measure, the additional process is needed to reduce the measure time. In this study, we made a dual-heat-flux thermometer to verify its performance and obtained an hour-long data from three subjects. Dual-heat-flux thermometer estimated the core body temperature very well in all subjects. In addition, least squares curve-fitting method predicted deep body temperature well with within 100 sec data. Autoregressive model with 10 sec data also seemed to be suitable method for shortening measure time of dual-heat-flux thermometer.

关键词： Heat flux

来源：评论

学校读者我要写书评

暂无评论

Fall detection algorithm for the elderly using acceleration sensors on the shoes

Fall detection algorithm for the elderly using acceleration ...

引用

Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： S. Y. Sim H. S. Jeon G. S. Chung S. K. Kim S. J. Kwon W. K. Lee K. S. Park Interdisciplinary program of bioengineering College of Engineering Seoul national university Department of biomedical engineering College of Medicine Seoul National University

ISBN: (纸本)9781424441211

The rate of increase in the number of aging population in Korea is very rapid among OECD-member countries. And fall accident is one of the most common factors that threaten the health of the elderly. Therefore, it is needed to develop a fall detection system for the elderly. Most fall detection systems use accelerometers attached on the torso. And in various studies, it was verified that these systems have high sensitivity and high specificity. However, the elderly would feel uncomfortable when banding a sensor on the chest every day. Therefore, in this study, we attached an accelerometer on the shoes to detect fall in the elderly. This prototype system would be improved as a smaller, low-power system in the next study. Also, applying energy harvesting device to this shoe system is being developed to reduce the weight of battery.

关键词： footwear Detection systems acceleration transducer aged person accelerometers falls Fall Autumn Detection algorithms Torso energy harvesting accidents and falls

来源：评论

学校读者我要写书评

暂无评论

Validation of heart rate extraction through an iPhone accelerometer

Validation of heart rate extraction through an iPhone accele...

引用

Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Sungjun Kwon Jeongsu Lee Gih Sung Chung Kwang Suk Park Interdisciplinary Program of Bioengineering Seoul National University Department of Biomedical Engineering College of Medicine Seoul National University

ISBN: (纸本)9781424441211

Ubiquitous medical technology may provide advanced utility for evaluating the status of the patient beyond the clinical environment. The iPhone provides the capacity to measure the heart rate, as the iPhone consists of a 3-axis accelerometer that is sufficiently sensitive to perceive tiny body movements caused by heart pumping. In this preliminary study, an iPhone was tested and evaluated as the reliable heart rate extractor to use for medical purpose by comparing with reference electrocardiogram. By comparing the extracted heart rate from acquired acceleration data with the extracted one from ECG reference signal, iPhone functioning as the reliable heart rate extractor has demonstrated sufficient accuracy and consistency.

关键词： Heart rate Accelerometer IPhone Ubiquitous healthcare

来源：评论

学校读者我要写书评

暂无评论

SAT0015 The negative effects of glucocorticoids on bone are primarily mediated by genes involved in osteoblast differentiation and bone remodelling

引用

Annals of the Rheumatic Diseases 2012年 71卷 476-476页

作者： K.I. Blankenstein T.C. Brennan-Speranza K. Lyon C.R. Dunstan F. Buttgereit H. Zhou M.J. Seibel 1Bone Research Program ANZAC Research Institute Sydney Australia 2Dept. of Rheumatology and Clinical Immunology Charité University Medicine Berlin Germany 3Biomedical Engineering Faculty of Engineering University of Sydney 4Department of Endcrinology and Metabolism Concord Hospital Sydney Australia

Background Long-term and high-dose treatment with glucocorticoids causes bone loss and can lead to secondary osteoporosis in both human and mice. The molecular mechanisms underlying the adverse effects of glucocorticoids on bone are not well understood. We recently demonstrated that osteoblast-targeted disruption of glucocorticoid signalling attenuates glucocorticoid-induced bone loss in mice, indicating that the detrimental skeletal effects of glucocorticoids are predominantly mediated by osteoblasts. Objectives To further determine the role of the osteoblast in glucocorticoid-induced bone loss, we aimed to elucidate the effects of glucocorticoids on the gene expression profile in bone cells. Methods Seven-week old male CD1 outbred mice were subcutaneously implanted with slow-release pellets containing either 1.5 mg corticosterone (CS) or placebo (PLC) over 28 days. Blood was obtained weekly and osteocalcin serum levels were measured by IRMA. RNA was isolated from tibia at endpoint (day 28) and Affymetrix Gene Array analysis (GeneSpring GX) was performed to assess changes in expression of genes associated with osteoblast differentiation and the regulation of bone remodelling. Genes considered to be regulated were at least 1.5-fold differentially expressed. Quantitative RT-PCR was employed to validate the gene array results on a selection of genes. Results By comparing gene expression profiles in RNA from mice treated with corticosterone or placebo, we found that corticosterone specifically regulated 391 genes. To further investigate the genes targeted by corticosterone treatment we performed gene ontology analysis with the aid of heat maps. We found that the expression of genes implicated in osteoblast differentiation and the regulation of bone remodelling was downregulated in mice treated with corticosterone compared to placebo. We observed a downregulation of the osteoblast markers Runx2, Colα1, osteocalcin and sclerostin in corticosterone-treated mice compared t

关键词：

来源：评论

学校读者我要写书评

暂无评论

Characterization of human primary chondrocytes of osteoarthritic cartilage at varying severity

引用

Chinese Medical Journal 2011年第24期000卷 4245-4253页

作者： YIN Jing YANG Zheng CAO Yong-ping GE Zi-gang Department of Biomedical Engineering College of EngineeringPeking University Beijing 100871 China Department of Orthopaedic Surgery Yong Loo Lin School ofMedicine NUS Tissue Engineering Program National Universityof Singapore 119260 Singapore Department of Orthopaedics Peking University First Hospital Beijing 100034 China Center for Biomaterials and Tissue Engineering Academy for Advanced Interdisciplinary Studies Peking University Beijing 100871 China

Background There is a difficulty in evaluating the in heterogeneity among cartilage affected by osteoarthritis vivo functionality of individual chondrocytes, and there is much （OA）. In this study, in vitro cultured chondrocytes harvested from varying stages of degeneration were studied as a projective model to further understand the pathogenesis of osteoarthritis. Methods Cartilage of varying degeneration of end-stage OA was harvested, while cell yield and matrix glycosaminoglycan （GAG） content were measured. Cell morphology, proliferation, and gene expression of collagen type 1,‘11, and X, aggrecan, matrix metalloproteinase 13 （MMP-13）, and ADAMTS5 of the acquired chondrocytes were measured during subsequent in vitro culture. Results Both the number of cells and the GAG content increased with increasing severity of OA. Cell spreading area increased and gradually showed spindle-like morphology during in vitro culture. Gene expression of collagen type II, collagen type X as well as GAG decreased with severity of cartilage degeneration, while expression of collagen type I increased. Expression of MMP-13 increased with severity of cartilage degeneration, while expression of ADAMTS-5 remained stable. Expression of collagen type II, X, GAG, and MMP-13 substantially decreased with in vitro culture. Expression of collagen type I increased with in vitro cultures, while expression of ADAMTS 5 remained stable. Conclusions Expression of functional genes such as collagen type Ⅱ and GAG decreased during severe degeneration of OA cartilage and in vitro dedifferentiation. Gene expression of collagen I and MMP-13 increased with severity of cartilage degeneration.

关键词： osteoarthritis chondroeyte differentiation

来源：评论

学校读者我要写书评

暂无评论

Evaluating pharmaceutical assistance activities in Brazilian hospitals

Evaluating pharmaceutical assistance activities in Brazilian...

引用

Pan American Health Care Exchanges, PAHCE

作者： A. Nascimento S. R. Castilho R. M. V. R. Almeida A. F. C. Infantosi Biomedical Engineering Program /COPPE UFRJ Rio de Janeiro Brazil Pharmacy Faculty UFF Niteroi Brazil

This work aims at identifying and evaluating the associations between the pharmaceutical assistance activities in hospital pharmacies services (HPS). The Multiple Correspondence Analysis (MCA) was applied to a sample of 238 hospitals and 30 variables from the survey Diagnosis of Hospital Pharmacy in Brazil. The first dimension of the MCA explained 90.6% of the data variability and allowed discriminate the HPS according to the presence or not of activities. It is noticeable an association between the presence of activities and better categories with large hospitals.

关键词： Hospitals Drugs Conferences Logistics IEEE catalog Couplings

来源：评论

学校读者我要写书评

暂无评论

Corrigendum to “Unintended consequences of regulating drinking water in rural Canadian communities: Examples from Atlantic Canada” [Health and Place 17(5) (2011) 1030–1037]

引用

Health & Place 2012年第2期18卷 446-446页

作者： Megan Kot Heather Castleden Graham A. Gagnon Interdisciplinary PhD Program Faculty of Graduate Studies Dalhousie University Halifax Nova Scotia Canada B3J 1Z1 School for Resource and Environmental Studies Faculty of Management Dalhousie University Halifax Nova Scotia Canada B3H 4R2 Civil and Resource Engineering Faculty of Engineering Dalhousie University Halifax Nova Scotia Canada B3J 1Z1

来源：评论

学校读者我要写书评

暂无评论

Effect of the electrostatic potential on the internalization mechanism of cell penetrating peptides

Effect of the electrostatic potential on the internalization...

引用

2011 AIChE Annual Meeting, 11AIChE

作者： Flores, Karen A. Salgado, J. Cristian Zapata-Torres, Gerald Gerdtzen, Ziomara P. Gonzalez, María-Julieta Hermoso, Marcela A. Laboratory of Process Modeling and Distributed Computing Department of Chemical Engineering and Biotechnology University of Chile Santiago Chile Millennium Institute for Cell Dynamics and Biotechnology Centre for Systems Biology University of Chile Santiago Chile Department of Inorganic and Analytical Chemistry Faculty of Chemical and Pharmaceutical Sciences University of Chile Santiago Chile Centre for Biochemical Engineering and Biotechnology Department of Chemical Engineering and Biotechnology University of Chile Santiago Chile Laboratory of Cell Biology Cell and Molecular Program Faculty of Medicine University of Chile Santiago Chile Laboratory of Innate Immunology Institute of Biomedical Sciences University of Chile Santiago Chile

来源：评论

学校读者我要写书评

暂无评论

Distance estimation from acceleration for quantitative evaluation of Parkinson tremor

Distance estimation from acceleration for quantitative evalu...

引用

Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： Hyoseon Jeon Sang Kyong Kim BeomSeok Jeon Kwang Suk Park Interdisciplinary Program in Medical and Biological Engineering Graduate School Seoul National University South Korea Department of Neurology Seoul National University Hospital South Korea Department of Biomedical Engineering College of Medicine Seoul National University South Korea

The purpose of this paper is to assess Parkinson tremor estimating actual distance amplitude. We propose a practical, useful and simple method for evaluating Parkinson tremor with distance value. We measured resting tremor of 7 Parkinson Disease (PD) patients with triaxial accelerometer. Resting tremor of participants was diagnosed by Unified Parkinson's Disease Rating Scale (UPDRS) by neurologist. First, we segmented acceleration signal during 7 seconds from recorded data. To estimate a displacement of tremor, we performed double integration from the acceleration. Prior to double integration, moving average method was used to reduce an error of integral constant. After estimation of displacement, we calculated tremor distance during 1s from segmented signal using Euclidean distance. We evaluated the distance values compared with UPDRS. Averaged moving distance during 1 second corresponding to UPDRS 1 was 11.52mm, that of UPDRS 2 was 33.58mm and tremor distance of UPDRS 3 was 382.22 mm. Estimated moving distance during 1s was proportional to clinical rating scale — UPDRS.

关键词： Acceleration Accelerometers Educational institutions Three dimensional displays Surgery Thumb

来源：评论

学校读者我要写书评

暂无评论

The application of a real-time rapid-prototyping environment for the behavioral rehabilitation of a lost brain function in rats

The application of a real-time rapid-prototyping environment...

引用

IEEE Symposium on Computational Intelligence, Cognitive Algorithms, Mind, and Brain

作者： Pruckl, R. Grünbacher, E. Ortner, R. Taub, A.H. Hogri, R. Magal, A. Segalis, E. Zreik, M. Nossenson, N. Herreros, I. Giovannucci, A. Almog, R. Ofek Bamford, S. Marcus-Kalish, M. Shacham, Y. Verschure, P.F.M.J. Messer, H. Mintz, M. Scharinger, J. Silmon, A. Guger, C. G.tec - Guger Technologies OG Schiedlberg Austria Psychobiology Research Unit Department of Psychology Tel Aviv University Israel Department of Biomedical Engineering Tel Aviv University Israel School of Electrical Engineering Tel Aviv University Israel SPECS Lab. of Synthetic Perceptive Emotive and Cognitive Systems University Pompeu Fabra Barcelona Spain Faculty of Engineering Tel Aviv University Israel Istituto Superiore di Sanitá Rome Italy Interdisciplinary Center for Technology Analysis and Forecasting Tel Aviv University Israel Department of Computational Perception Johannes Kepler University Linz Austria INEX Newcastle University Newcastle United Kingdom

ISBN: (纸本)9781424498918

In this paper we propose a Rapid Prototyping Environment (RPE) for real-time biosignal analysis including ECG, EEG, ECoG and EMG of humans and animals requiring a very precise time resolution. Based on the previous RPE which was mainly designed for developing Brain Computer Interfaces (BCI), the present solution offers tools for data preprocessing, analysis and visualization even in the case of high sampling rates and furthermore tools for precise cognitive stimulation. One application of the system, the analysis of multi-unit activity measured from the brain of a rat is presented to prove the efficiency of the proposed environment. The experimental setup was used to design and implement a biomimetic, biohybrid model for demonstrating the recovery of a learning function lost with age. Throughout the paper we discuss the components of the setup, the software structure and the online visualization. At the end we present results of a real-time experiment in which the model of the brain learned to react to he acquired signals. © 2011 IEEE.

关键词： Brain

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：