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Review on fate, transport, toxicity and health risk of nanoparticles in natural ecosystems: Emerging challenges in the modern age and solutions toward a sustainable environment

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The Science of the total environment 2024年 912卷 169331页

作者： Thien-Khanh Tran Minh-Ky Nguyen Chitsan Lin Tuan-Dung Hoang Thanh-Cong Nguyen Aasif Mohmad Lone Akhil Pradiprao Khedulkar Mohamed S Gaballah Jagpreet Singh W Jin Chung D Duc Nguyen Advanced Applied Sciences Research Group Dong Nai Technology University Bien Hoa City 76100 Viet Nam Faculty of Technology Dong Nai Technology University Bien Hoa City 76100 Viet Nam. Faculty of Environment and Natural Resources Nong Lam University Hamlet 6 Linh Trung Ward Thu Duc City Ho Chi Minh City 700000 Viet Nam Ph.D. Program in Maritime Science and Technology National Kaohsiung University of Science and Technology Kaohsiung 81157 Taiwan. Electronic address: nmky@hcmuaf.edu.vn. Ph.D. Program in Maritime Science and Technology National Kaohsiung University of Science and Technology Kaohsiung 81157 Taiwan Department of Marine Environmental Engineering National Kaohsiung University of Science and Technology Kaohsiung 81157 Taiwan. School of Chemistry and Life Science Hanoi University of Science and Technology No. 1 Dai Co Viet Hai Ba Trung Hanoi 100000 Viet Nam Vietnam National University Hanoi VNU Town Hoa Lac Thach That District Hanoi 155500 Viet Nam. Department of Civil Engineering Manipal Institute of Technology Manipal Academy of Higher Education Manipal 576104 Karnataka India. Department of Biomedical Engineering and Environmental Science National Tsing Hua University Hsinchu 30013 Taiwan. CAS Key Laboratory of Urban Pollutant Conversion Department of Environmental Science and Engineering University of Science and Technology of China Hefei 230026 China School of Engineering and Technology Central Michigan University Mt. Pleasant MI 48859 USA. Department of Chemistry University Centre for Research and Development Chandigarh University Gharuan Mohali 140413 India. Department of Civil & Energy System Engineering Kyonggi University Suwon 16227 South Korea. Department of Civil & Energy System Engineering Kyonggi University Suwon 16227 South Korea Institute of Applied Technology and Sustainable Development Nguyen Tat Thanh University Ho Chi Minh City 700000 Viet Nam. Electronic address: nguyensyduc@gmail.com.

In today's era, nanoparticles (NPs) have become an integral part of human life, finding extensive applications in various fields of science, pharmacy, medicine, industry, electronics, and communication. The increasing popularity of NP usage worldwide is a testament to their tremendous potential. However, the widespread deployment of NPs unavoidably leads to their release into the environmental matrices, resulting in persistence in ecosystems and bioaccumulation in organisms. Understanding the environmental behavior of NPs poses a significant challenge due to their nanoscale size. Given the current environmental releases of NPs, known negative consequences, and the limited knowledge available for risk management, comprehending the toxicity of NPs in ecosystems is both awaiting and crucial. The present review aims to unravel the potential environmental influences of nano-scaled materials, and provides in-depth inferences of the current knowledge and understanding in this field. The review comprehensively summarizes the sources, fate, transport, toxicity, health risks, and remediation solutions associated with NP pollution in aquatic and soil ecosystems. Furthermore, it addresses the knowledge gaps and outlines further investigation priorities for the sustainable control of NP pollution in these environments. By gaining a holistic understanding of these aspects, we can work toward ensuring the responsible and sustainable use of NPs in today's fast-growing world.

关键词： Bioavailability Fate and transport Nanosized particles Nanotoxicology Silver nanoparticles Toxicity

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Characterization of complete mitochondrial genome of two-spot swimming crabCharybdis bimaculata(Miers, 1886)

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Mitochondrial DNA Part B 2018年第2期3卷 900-901页

作者： Nack-Keun Kim Sapto Andriyono Ah Ran Kim Chung Il Lee Hyun-Woo Kim Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of Korea Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaDepartment of Marine Fisheries and Marine Faculty Universitas Airlangga C Campus Jl Mulyorejo Surabaya East Java Indonesia Department of Marine Bioscience Gangneung-Wonju National University Gangneung Republic of Korea Interdisciplinary Program of Biomedical Mechanical and Electrical Engineering Pukyong National University Busan Republic of KoreaDepartment of Marine Biology Pukyong National University Busan Republic of Korea

The two-spot swimming crabCharybdis bimaculata(Miers,1886) is an important decapod species in the benthic ecosystem of Korean waters. In this study, we determined its complete mitochondrial genome by the combination of NGS analysis using MiSeq platform and PCR-based cloning method. The circular mitochondrial genome ofC. bimaculatawas 15,714 bp in length in which the standard set of 13 protein-coding genes, 22 tRNA genes, and 2 rRNA genes were encoded. Phylogenic analysis showed *** most closely related toCharybdis feriata. The complete mitogenome sequence information ofC. bimaculatawould provide useful data for the conservation of their population in the Pacific ocean.

关键词： Next generation sequencing Charybdis bimaculata mitogenome decapod phylogeny

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Detection of gas concentrations based on age on Staphylococcus aureus biofilms with gas array sensors

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AIP Conference Proceedings 2020年第1期2314卷

作者： A. A. S. Pradhana S. D. Astuti M. Khasanah R. K. D. Ardianti 1)Biomedical Engineering Master Program Post Graduate School Universitas Airlangga Surabaya 60115 Indonesia 2)Department of Physics Faculty Science and Technology Universitas Airlangga Surabaya 60115 Indonesia 3)Department of Physics Faculty Science and Technology Universitas Airlangga Surabaya 60115 Indonesia 4)Biomedical Engineering Bachelor Program Post Graduate School Universitas Airlangga Surabaya 60115 Indonesia

Bacteria that have developed in the biofilm phase will be more resistant to antibiotics and emit gases that have certain characteristics. One dose of culture from Trypticase Soy Broth (TSB) (Merck, Germany) was inoculated into 10 mL of Trypticase Soy Broth (TSB) (Merck, Germany) and homogenized for a concentration of 0.5 McFarland (10-13 CFU / mL). The suspension was detected by ELISA reader (λ 595nm)Based on the results that have been obtained, the sensor on the gas array instrument can detect both a variety of distinctive gas patterns in S. Variations in shelf life and variations in the types of samples provided can be tracked both by the entire sensor. This is indicated by the emergence of a unique and different sensor voltage output pattern in each variation. The processing of sensor output using the PCA (Principal Component Analysis) method can accommodate 86.45% of the data variation, including the first component and the second component respectively 70.4% and 18.1%. Through the PCA method, each variation of bacterial treatment can be classified properly, so it can be used to clearly distinguish the age of bacteria and biofilm age. When loading the PCA plot, the MQ2 sensor shows the most responsive results to gas changes. Meanwhile, the MQ136 sensor ranks second as the most responsive sensor to measure the life span of bacteria and biofilms.

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The effect of polystyrene addition in characteristics of zinc oxide eugenol dental cement

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AIP Conference Proceedings 2020年第1期2314卷

作者： Prihartini Widiyanti Siswanto Betanty Prasetya Sadewi 1Biomedical Engineering Study Program Department of Physics Faculty of Science and Technology Universitas Airlangga Surabaya Indonesia 2Departement of Physics Faculty of Science and Technology Universitas Airlangga Surabaya Indonesia

Zinc oxide-eugenol cements are easier to be tolerated by tissue than other dental materials. They could relieve pain, antibacterial and antiseptic. The cements provide better sealing properties than other type of cements. They used as temporary filling materials, gingival dressings due to their poor mechanic properties. In order to increase the mechanical properties and to reduce solubility of this cement,the additive must be added in the composition of this cement. This study used dental materials, namely zinc oxide eugenol dental cement and polystyrene additives. The sample used in this study was made of the dental cement composition of zinc oxide eugenol cement without the addition of additives polystyrene and with the addition of 2%, 5% and 10% variations of *** results of the tensile strength test and compressive strength test are showed that the larger the percentage of polystyrene additives added to the samples, the greater the two parameters of mechanical strength. This result was in accordance with microstructure characteristic using Scanning Electron Microscopy (SEM) which showed that the greater the percentage of the polystyrene additive, the more subtle the connection between the cement and the teeth.

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Hydroxyapatite-gelatin-HPMC composite as injectable bone substitute with alendronate variation for osteoporotic bone

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AIP Conference Proceedings 2020年第1期2314卷

作者： Novita Sari Alfian Pramudita Putra Siswanto Muhammad Fajar Faliasthiunus Pradipta Dyah Hikmawati 1Department of Physics Faculty of Science and Technology Universitas Airlangga Surabaya Indonesia 2Biomedical Engineering Study Program Department of Physics Faculty of Science and Technology Universitas Airlangga Surabaya Indonesia

The treatment of bone with osteoporosis could be done by filling the bone defect with Injectable Bone Substitute (IBS). IBS could be functioned as drug delivery system by associating a drug inside the IBS, such as alendronate for osteoporosis case. In this study, IBS has been synthesized and characterized with the alendronate variations. The IBS was synthesized by stirring hydroxyapatite and gelatin 5% (w/v) with a ratio of 45:55. The alendronate was added to the solution with composition of 0%, 5%, 10%, 15% and 20%. The mixture was mixed with 2% (w/v) HPMC. FTIR test results indicated the formation of hydroxyapatite-gelatin bonding (Ca2+--COO−) at wavenumber of 1560.54 cm−1. The acidity test result indicated that the sample had a pH of 7 and was able to remain stable. The IBS could be set in 3 hours and 38 minutes when injected to HA substrate and capable of enveloping the surface of HA substrate. The pore size of the substrate decreased from range of 153 to 625.8 µm into 247.4 to 480.8 µm. The XRD test results indicated that degree of crystallinity decreased from 76.81% to 75.13%. The best alendronate composition in IBS was 10% compared to the mass of hydroxyapatite.

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Synthesis and characterization of acrylic resin with ultra high molecular weight polyethylene (UHMWPE) addition as dental prosthetic base

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AIP Conference Proceedings 2020年第1期2314卷

作者： Prihartini Widiyanti Siswanto Ika Fauziyatus Silfiana 1Biomedical Engineering Study Program Department of Physics Faculty of Science and Technology Universitas Airlangga Surabaya Indonesia 2Departement of Physics Faculty of Science and Technology Universitas Airlangga Surabaya Indonesia

Acrylic based resins are frequently used in daily dental practice. The most common use of the materials includes denture bases and denture liners. Dental prosthetic base is part of a denture that rests on the supporting network elements where the artificial tooth is placed. The problem with the denture base is the high incidence of dental base fracture due to masticatory pressure. This study is aimed to obtain the best properties of fiber acrylic resin as a dental prosthetic base by adding Ultra High Molecular Weight Polyethylene (UHMWPE). UHMWPE fiber length variation used was 0 mm, 2 mm, 4 mm, 6 mm, and 8 mm with a width of 2 mm fiber. The characterization test was porosity, density, compressive strength and hardness. The porosity test are showed that its best value was 1.695%, while the highest density test was 1.177 g/cm3. The highest compressive strength test was at 67.615 MPa and the highest hardness was 17.1 kgf/mm2. Based on all results,they are showed that the variation of UHMWPE fiber length with a width of 2 mm affected the physical and mechanical properties of dental prosthetic base materials.

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Preliminary study of the polymesoda expansa based hydroxyapatite for medical devices coating application

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AIP Conference Proceedings 2020年第1期2306卷

作者： M. Riza Roslan N. F. Mohd Nasir M. A. Gilani Nur Farahiyah Mohammad E. M Cheng M. F. Abdul Khalid A. S. Zoolfakar N. A. M. Amin S. F. Khan 1Biomedical Electronic Engineering Program School of Mechatronic Engineering Universiti Malaysia Perlis Perlis Malaysia 2Microwave Research Institute (MRI) Universiti Teknologi Mara Shah Alam Malaysia 3Faculty of Electrical Engineering Universiti Teknologi Mara Shah Alam Malaysia 4Mechanical Engineering Program School of Mechatronic Engineering Universiti Malaysia Perlis Perlis Malaysia

Hydroxyapatite (HA) which is a group of calcium phosphate (CaP) is used as a medical devices coating due to its ability to increase the bioactivity and biocompatibility of the device surface. The attraction of using waste seashells products is interesting due to its sustainability and low cost solution especially in biomedical application. Polymesoda expansa or locally known as Lokan is potentially rich with calcium carbonate (CaCO3). Here, the synthesis of HA was done via precipitation method by utilizing the Polymesoda expansa (Lokan) shells as the resource of calcium precursors. Hydroxyapatite synthesized from Polymesoda expansa was carried out with different pH solution (pH 9 and 13) in alkaline environment. The effects of pH on the morphological and chemical composition properties as well as the Ca/P ratio of HA powders were analyzed through Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR), and Energy Dispersive X-ray Spectrometry (EDS). The finding demonstrates as the pH increases, the calcium apatite reduced and this had increases the Ca/P ratio.

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Potential anti-biofilm producing marine actinomycetes isolated from sea sediments in Thailand

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Agriculture and Natural Resources 2018年第3期52卷 228-233页

作者： Leetanasaksakul, Kantinan Thamchaipenet, Arinthip Department of Genetics Faculty of Science Kasetsart University Bangkok 10900 Thailand Interdisciplinary Graduate Program in Genetic Engineering Graduate School Kasetsart University Bangkok 10900 Thailand Center for Advanced Studies in Tropical Natural Resources Kasetsart University Bangkok 10900 Thailand

Marine actinomycetes are well known as novel resources of bioactive compounds including anti-biofilm agents with various therapeutic applications. In this study, one hundred and one marine actinomycetes were isolated from sea sediments collected from Andaman sea and the Gulf of Thailand. Morphological study and partial 16S rDNA sequence analysis revealed that most of isolates belong to genus Streptomyces (n = 90, 89.11%) and the rest are rare actinomycetes (n = 11, 10.89%) including Actinopolymorpha, Actinomycetospora, Dietzia Nocardiopsis, Micromonospora and Mycobacterium. Among them, ten and thirteen strains significantly reduced more than 60% of biofilm formation of Escherichia coli and Staphylococcus aureus, respectively. But no such activity was found against Pseudomonas aeruginosa. Further analysis of their supernatants indicated that most of marine actinomycetes secreted non-toxic anti-biofilm agents and some accompanied with protease activity. These are preferred characteristics of anti-biofilm substances that potentially restricted biofilm forming of E. coli and S. aureus and simultaneously prevented bacteria to develop resistance. © 2018 Kasetsart University

关键词： Anti-biofilm Marine actinomycetes

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Genetically programmable Fusion Cellular Vesicles for Cancer Immunotherapy

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Angewandte Chemie 2021年第50期133卷

作者： Dr. Qian-Fang Meng Yuyue Zhao Dr. Chunbo Dong Dr. Lujie Liu Dr. Yuanwei Pan Jialin Lai Prof. Zhida Liu Prof. Guang-Tao Yu Prof. Xiaoyuan Chen Prof. Lang Rao Institute of Biomedical Health Technology and Engineering Shenzhen Bay Laboratory Shenzhen 518132 China Stomatological Hospital Southern Medical University Guangzhou 510280 China Shanxi Academy of Advanced Research and Innovation Taiyuan 030032 China Departments of Diagnostic Radiology Surgery Chemical and Biomolecular Engineering and Biomedical Engineering Yong Loo Lin School of Medicine and Faculty of Engineering National University of Singapore Singapore 119074 Singapore Clinical Imaging Research Centre Centre for Translational Medicine Yong Loo Lin School of Medicine National University of Singapore Singapore 117599 Singapore Nanomedicine Translational Research Program NUS Center for Nanomedicine Yong Loo Lin School of Medicine National University of Singapore Singapore 117597 Singapore

Herein, we report that genetically programmable fusion cellular vesicles (Fus-CVs) displaying high-affinity SIRPα variants and PD-1 can activate potent antitumor immunity through both innate and adaptive immune effectors. Dual-blockade of CD47 and PD-L1 with Fus-CVs significantly increases the phagocytosis of cancer cells by macrophages, promotes antigen presentation, and activates antitumor T-cell immunity. Moreover, the bispecific targeting design of Fus-CVs ensures better targeting on tumor cells, but less on other cells, which reduces systemic side effects and enhances therapeutic efficacies. In malignant melanoma and mammary carcinoma models, we demonstrate that Fus-CVs significantly improve overall survival of model animals by inhibiting post-surgery tumor recurrence and metastasis. The Fus-CVs are suitable for protein display by genetic engineering. These advantages, integrated with other unique properties inherited from source cells, make Fus-CVs an attractive platform for multi-targeting immune checkpoint blockade therapy.

关键词： CD47/SIRPα cell membrane nanoparticle genetic engineering immune checkpoint therapy PD-1/PD-L1

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The baby delivery method estimation using naïve bayes classification model for mobile application 8

The baby delivery method estimation using naïve bayes class...

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8th International Conference on Theoretical and Applied Physics, ICTAP 2018

作者： Iftitah, Ewika Nadya Rulaningtyas, Riries Ernawati Biomedical Engineering Study Program Department of Physics Airlangga University Jl. Mulyorejo Surabaya60115 Indonesia Department of Obstetric and Gynecology Medical Faculty Airlangga University Jl. Mulyorejo Surabaya60115 Indonesia

The maternal mortality rate because of cesarean delivery is still high caused by lack of knowledge of pregnant women about the high risk of pregnancy. Cesarean delivery is an alternative labor but remains at high risk for both mother and fetus. The awareness of the mother to check her pregnancy early and precisely is very important. To support the awareness attitude of pregnant women to their health, so in this research has made an application program for the mobile application based on Android by using Naïve Bayes classification model to predict early childbirth process that will be undertaken. From this research, it can be concluded that the application of the baby delivery method estimation with Naïve Bayes model based on Android can educate pregnant women about high-risk pregnancy condition and prediction of delivery method that will be done with 90% accuracy, 100% sensitivity, and 80% specificity. © Published under licence by IOP Publishing Ltd.

关键词： Application programs

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