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Machine-learning-based sampling inspection under OQC capacity for real-time quality monitoring in the TFT-LCd industry

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international Journal of Production Research 2025年第6期63卷 2090-2113页

作者： Shih, Ming-Sung Chen, James C. Chen, Tzu-Li Chiang, Chih-Hsiung Hsu, Ching-Lan International Intercollegiate Ph.D. Program National Tsing Hua University Hsinchu Taiwan Department of Industrial Engineering and Engineering Management National Tsing Hua University Hsinchu Taiwan Graduate Institute of Intelligent Manufacturing Technology National Taiwan University of Science and Technology Taipei Taiwan Division of Quality Control AUO Corporation Taichung Taiwan

In the thin film transistor-liquid crystal display (TFT-LCd) industry, the competition is fierce, and the external failure cost is high. To improve the quality of released products, sampling inspection under outgoing quality control (OQC) is conducted before products are released. Owing to the variety and complexity of inspection items, the task must be carried out manually while realising automation is difficult. Traditional random sampling inspection is limited by sampling quantity, manpower, and material resources. To effectively improve acceptable quality levels, this paper proposes a quality predictive monitoring framework tailored to the production and inspection characteristics of the TFT-LCd industry. This framework includes real-time automatic quality monitoring based on an optimal machine learning prediction model with two-phase feature creation, and it also addresses OQC inspection capacity constraints. Experimental results show the prediction performance based on proposed model is better than the traditional random sampling process. In practice, superior average outgoing quality improves by more than 70% at the same sampling level. In addition, the features of the process can be further controlled and managed based on the prediction model to monitor the key parameters in real time and respond to abnormalities quickly, thereby further improving the quality of released products. © 2024 Informa UK Limited, trading as Taylor & Francis Group.

关键词： Liquid crystal displays

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Exploring the Interaction dynamics of Growth-Promoting Bacterial Endophytes and Fertilizer on Oryza sativa L. Under Heat Stress

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Rice 2025年第1期18卷 1-16页

作者： dlamini, Wonder Nathi Yu, Kuo-Pin Chen, Wen-Ching Shen, Fo-Ting Department of Soil and Environmental Sciences National Chung-Hsing University No. 145 Xingda Rd. South Dist Taichung 402 Taiwan International Ph.D. Program in Environmental Science and Technology National Yang Ming Chiao Tung University No.155 Sec. 2 Li-Nong Street Taipei 112304 Taiwan International Bachelor Program of Agribusiness National Chung-Hsing University 145 Xingda Rd. Taichung 402 Taiwan Innovation and Development Center of Sustainable Agriculture (IDCSA) National Chung Hsing University No. 145 Xingda Road South District Taichung 40227 Taiwan Institute of Environmental and Occupational Health Sciences National Yang Ming Chiao Tung University No. 155 Sec. 2 Li-Nong Street Taipei 112304 Taiwan

The demand for rice (Oryza sativa L.) as a staple food continues to grow, but rising temperatures due to climate change pose a significant threat to its production. This study addresses the challenge by employing endophytic bacteria and fertilizer to mitigate the adverse effects of high temperatures on rice plants. Seedlings were evaluated for growth parameters, comparing outcomes with non-inoculated counterparts under normal and 40 to 45 °C heat shock conditions. Isolates underwent thorough dNA extraction and 16 S rRNA gene sequencing for identification and were scrutinized for their plant growth-promoting (PGP) traits. The effects of fertilizer and thermotolerant bacteria on rice plants were investigated in controlled chambers at 25 °C for 14 days, succeeded by exposure to 40 °C for 10 days. A consecutive soil pot experiment extended over 150 days, exposing plants to growth chambers set at 35 °C for 60 days, followed by a rapid increase to 40 °C for 30 days and a subsequent reduction to 35 °C for an additional 60 days. Inoculating with the isolates resulted in panicle development and increased plant biomass and length, with fresh grain weights showing a 50% improvement when using bacterial strain W (B. paralicheniformis). Additionally, dry grain weights per panicle rose by 113% with strain W, 83% with strain N (B. pumilus), and 87% with strain d (B. paranthracis) compared to the control. Bacterial strain W exhibited the most pronounced effect on rice yield under heat stress. The results demonstrated a decrease in malondialdehyde (MdA) levels after 150 days of heat stress and half-dose of the recommended fertilizer. Bacterial inoculation increased proline, salicylate, and abscisic acid content, suggesting the alleviation of osmotic stress effects. This highlights the role of endophytic bacteria in stimulating biologically active responses within rice plant cells. Notably, bacterial strains W, N, and d show potential for enhancing plant growth and mitigating heat st

关键词： Bacterial endophytes Fertilizer interaction Growth promotion Heat stress mitigation High temperature Rice (Oryza sativa)

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Chemical Characteristics of Stack Particulate Matter Emitted from Sintering Process of an Integrated Steel Mill and Resolution of Source Contributors on Boundary PM_2.5

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Aerosol and Air Quality Research 2025年第6期25卷 1-14页

作者： Shao, Cheng-Tsung Tseng, Yu-Lun Yuan, Chung-Shin Cheng, Wen-Hsi Li, Nian-Jie Zhao, Jia-Yi Institute of Environmental Engineering National Sun Yat-Sen University Kaohsiung City Taiwan Net Zero Emissions and Resource Recycling Technology Research Center National Sun Yat-Sen University Kaohsiung City Taiwan Environmental Protection Department China Steel Corporation Kaohsiung City Taiwan Ph.D. Program in Maritime Science and Technology College of Maritime National Kaohsiung University of Science and Technology Kaohsiung City Taiwan

Background: This study investigated the chemical characteristics of PM2.5 emitted from the sintering process of an integrated steel mill and assesses the contribution of emission sources to boundary PM2.5. Methods: PM... 详细信息

Background: This study investigated the chemical characteristics of PM_2.5 emitted from the sintering process of an integrated steel mill and assesses the contribution of emission sources to boundary PM_2.5. Methods: PM_2.5 samples were simultaneously collected from three stacks of the sintering process and two boundary sites located at the upstream (Site N) and downstream (Site S) of the steel mill. The chemical compositions of PM_2.5, including water-soluble ions (WSIs), metallic elements, carbonaceous matter, anhydrosugars, and organic acids, were further analyzed. The chemical mass balance (CMB) receptor model was then employed to identify emission sources and quantify their contributions. Results and discussion: Stack emissions revealed that the dominant anions (SO₄²⁻, NO₃⁻, Cl⁻) and cations (Na⁺, NH₄⁺, and Ca²⁺) were similar across TPM, FPM, and CPM fractions. Fe, Al, and Ca were the most abundant metals, while organic carbon (OC) dominated the carbonaceous content, primarily from coke oven gas and solid fuel combustion. At the boundary sites, PM_2.5 concentrations were generally higher at Site S, especially in fall and winter, due to fugitive dust from raw material handling and heavy-duty truck activities. Seasonal variation of PM_2.5 concentrations followed the order: winter > fall > spring > summer. dominant WSIs included NO₃⁻, SO₄²⁻, NH₄⁺, Cl⁻, and Na⁺, and the key metals were Fe, Ca, Mg, Al, and Zn. The OC/EC ratios ranged from 1.49–1.88 and were slightly higher at Site N. Source apportionment showed that the steel mill contributed 28.3% and 36.6% of PM_2.5 at Sites N and S, respectively, with the sintering process being the largest contributor (3.37% at Site N and 12.4% at Site S). Conclusions: The sin

关键词： Chemical characteristics Particulate matter Source apportionment Spatiotemporal variation Stack and field samplings

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Cytocompatible and antibacterial Fe-, Cu- and Zn-substituted calcium hydroxyapatite materials for skin applications

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Ceramics international 2025年第9期51卷 11286-11296页

作者： Lukaviciute, L. Lukowiak, A. Stankeviciute, Z. Junka, A. Mortimer, M. Zarkov, A. Yang, J.-C. Ganceviciene, R. Kareiva, A. Faculty of Chemistry and Geosciences Vilnius University Naugarduko st. 24 Vilnius03225 Lithuania Institute of Low Temperature and Structure Research Polish Academy of Sciences Okolna 2 Wroclaw50422 Poland Department of Pharmaceutical Microbiology and Parasitology Wroclaw Medical University Borowska 211A Wroclaw50556 Poland Laboratory of Environmental Toxicology National Institute of Chemical Physics and Biophysics Akadeemia tee 23 Tallinn12618 Estonia Graduate Institute of Nanomedicine and Medical Engineering International Ph.D. Program in Biomedical Engineering College of Biomedical Engineering Research Center of Biomedical Device Research Center of Digital Oral Science and Technology Taipei Medical University Taiwan Faculty of Medicine Vilnius University M.K. Ciurlionio st. 21 Vilnius03101 Lithuania

Calcium hydroxyapatite (C10(PO4)6(OH)2;CHAp) and metal-substituted samples (Fe:CHAp, Cu:CHAp, and Zn:CHAp) were synthesized using a recently developed method. This method involved the wet precipitation of amorphous calcium phosphate (ACP), followed by solid-state reaction synthesis of α-tricalcium phosphate (α-TCP), and finally hydrothermal synthesis of CHAp. The effect of Fe3+, Cu2+, and Zn2+ substitution on the phase purity and antimicrobial properties of CHAp are summarized in this study. Notably, it highlights the phase purity of CHAp and Zn:CHAp (in the presence of Fe3+ and Cu2+ ions, the α- and β-TCP phases have formed) as well as the antimicrobial activity of Zn:CHAp and Cu:CHAp against Staphylococcus aureus and Candida albicans. The synthesized nanosized CHAp, Fe:CHAp, Cu:CHAp, and Zn:CHAp samples were used as additives in the preparation of skin creams. In vitro biological studies of the resulting skin creams demonstrated their antimicrobial activity against Pseudomonas aeruginosa, and showed a reduction in osteoblasts cells viability of in the range of 20–40 %. The addition of zinc enhances antimicrobial efficacy but reduces biocompatibility, while copper maintains both high antimicrobial activity and biocompatibility, making it more suitable for the development of medical or cosmetic materials. dermal creams containing CHAp with copper and iron ions also show significant antimicrobial activity while preserving good cell viability. These results highlight the importance of optimizing the balance between antimicrobial effectiveness and biocompatibility in these materials. © 2024

关键词： Biocompatibility

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Graphene quantum dot-decorated TiO2 nanowires/nanotubes: enhanced photocatalysis for methylene blue and pesticide degradation

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Applied physics A: Materials science and Processing 2025年第4期131卷

作者： Uyen, Ngo Ngoc Tu, Ly Anh Le, phuoc Huu Faculty of Applied Science Ho Chi Minh City University of Technology-VNUHCM 268 Ly Thuong Kiet Street District 10 Ho Chi Minh70000 Viet Nam Center for Plasma and Thin Film Technologies and International Ph.D. Program in Plasma and Thin Film Technology Ming Chi University of Technology New Taipei243303 Taiwan Department of Physics and Biophysics Faculty of Basic Sciences Can Tho University of Medicine and Pharmacy 179 Nguyen Van Cu Street Can Tho94000 Viet Nam

In this study, TiO2 nanowires/nanotubes (TiO2 WT) and graphene quantum dots-decorated TiO2 WT (GQds/TiO2 WT) were fabricated using a combination of anodic oxidation and hydrothermal methods. Both TiO2 WT and GQds/TiO2 WT exhibited anatase phase with preferred orientations along the (101), (004), (112), (200), and (105) planes. The TiO2 WT displayed a well-defined, uniform structure comprising nanotube arrays with an average diameter of ~ 100 nm and a length of ~ 4.8 μm, covered by nanowires with lengths of 2.5–3.5 μm. Amorphous GQds were successfully decorated onto TiO2 WT at various loading levels, as confirmed by XRd, SEM, HRTEM, EdS, Raman spectroscopy, and XPS. GQds/TiO2 WT demonstrated photocatalytic activity approximately twice as high as TiO2 WT for degrading methylene blue (MB) and pesticides, including methiocarb (MTC), carbofuran (CBF), and dimethoate (dMT). The photodegradation rates achieved for GQds-2/TiO2 WT were 1.336 × 10⁻2 min− 1 for MB, 20.3 × 10⁻2 min− 1 for CBF, 121 × 10⁻2 min− 1 for MTC, and 21.8 × 10⁻2 min− 1 for dMT. The enhanced performance was attributed to the synergistic effects of improved photogenerated electron-hole separation and extended light absorption compared to bare TiO2. Stability tests over four cycles of MB degradation showed ~ 80% retention of photocatalytic efficiency, indicating excellent reusability and structural stability. These results highlight the potential of GQds/TiO2 WT as a robust and efficient photocatalyst for environmental remediation, particularly for degrading organic pollutants and pesticides under UV-Vis illumination. © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2025.

关键词： Nanowires

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Structural optimization and biological evaluation of indolin-2-one derivatives as novel CdK8 inhibitors for idiopathic pulmonary fibrosis

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Biomedicine and pharmacotherapy 2025年 184卷 117891-117891页

作者： Hsu, Jui-Yi Hsu, Kai-Cheng Chou, Ching-Hsuan He, Tzu-Ying Lin, Tony Eight Sung, Tzu-Ying Yen, Shih-Chung Hsieh, Jui-Hua Yang, Chia-Ron Huang, Wei-Jan Ph.D. Program for Cancer Molecular Biology and Drug Discovery College of Medical Science and Technology Taipei Medical University and Academia Sinica Taipei Taiwan Graduate Institute of Cancer Biology and Drug Discovery College of Medical Science and Technology Taipei Medical University Taipei Taiwan Ph.D. Program for Cancer Molecular Biology and Drug Discovery College of Medical Science and Technology Taipei Medical University Taipei Taiwan Ph.D. Program in Drug Discovery and Development Industry College of Pharmacy Taipei Medical University Taipei Taiwan TMU Research Center of Cancer Translational Medicine Taipei Medical University Taipei Taiwan Cancer Center Wan Fang Hospital Taipei Medical University Taipei Taiwan School of Pharmacy College of Medicine National Taiwan University Taipei Taiwan Warshel Institute for Computational Biology School of Medicine The Chinese University of Hong Kong (Shenzhen) Shenzhen China Division of Translational Toxicology National Institute of Environmental Health Sciences National Institutes of Health Durham NC United States School of Pharmacy Taipei Medical University Taipei Taiwan

Cyclin-dependent kinase 8 (CdK8) plays a crucial role in the transforming growth factor beta (TGF-β) signaling pathway, which is critical to the pathology of idiopathic pulmonary fibrosis (IPF). CdK8 promotes the epithelial-mesenchymal transition (EMT) and excessive extracellular matrix (ECM) deposition, making it a promising target for IPF treatment. This study focused on optimizing F059–1017, a previously identified CdK8 inhibitor, to enhance its potency. Through integrated structure-based modifications, a series of compounds was synthesized, and their inhibitory effects on CdK8 were tested. Results indicated that substituting with cyclopentanone significantly improved the inhibitory activity, and compound 4j demonstrated the best potency (IC₅₀ = 16 nM). Notably, compared to F059–1017, its potency increased 35-fold, and kinase profiling revealed that the compound was selective for CdK8. Compound 4j inhibited the TGF-β1-induced EMT, cell migration, and morphological changes in A549 cells at a concentration of 0.1 μM and inhibited ECM and EMT protein expressions. In addition, the compound blocked TGF-β1-induced transcriptional changes and inhibited Smad3 and RNA polymerase II phosphorylation. These results highlight the potential of the optimized CdK8 inhibitor as a prospective drug for IPF treatment. © 2025 The Authors

关键词： Cyclin-dependent protein kinase 8 Epithelial-mesenchymal transition Indolin-2-one, Idiopathic pulmonary fibrosis Structural optimization Transforming growth factor beta

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development of BACE2-IN-1/tranylcypromine-based compounds to induce steroidogenesis-dependent neuroprotection

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Biomedicine and pharmacotherapy 2025年 183卷 117851-117851页

作者： Banerjee, Suddhasatwa Hsu, Ying-Ting Nguyen, duc-Hieu Yeh, Shiu-Hwa Liou, Ke-Chi Liu, Jr-Jiun Liou, Jing-Ping Chuang, Jian-Ying School of Pharmacy Taipei Medical University Taipei 11031 Taiwan Ph.D. Program in Medical Neuroscience Taipei Medical University and National Health Research Institutes Taipei 11031 Taiwan Institute of Biotechnology and Pharmaceutical Research National Health Research Institutes Miaoli County 35053 Taiwan TMU Research Center for Drug Discovery Taipei Medical University Taipei 11031 Taiwan Ph.D. Program in Drug Discovery and Development Industry College of Pharmacy Taipei Medical University Taipei 110 Taiwan International Master Program in Medical Neuroscience Taipei Medical University New Taipei City 23564 Taiwan TMU Research Center of Neuroscience Taipei Medical University Taipei 11031 Taiwan Department of Biomedical Science and Environmental Biology Kaohsiung Medical University Kaohsiung 80780 Taiwan

Traumatic brain injury (TBI) constitutes a significant burden on global healthcare systems, especially affecting younger populations, where it is a leading cause of disability and mortality. Current treatments for TBI mainly focus on preventing further brain damage and controlling symptoms. However, despite these approaches, several clinical needs remain unmet. Revelations from single-cell RNA sequencing (scRNA-seq) performed to determine cell-type heterogeneity and gene expression changes in brain tissue indicated that brain trauma increases the expression of lysine-specific demethylase 1 (LSd1) and secretase 2 (BACE2). To capitalize on this finding, a medicinal chemistry campaign was conducted to pragmatically insert tranylcypromine, an LSd1 inhibitor, into a carefully designed BACE2 inhibitory template (BACE2-IN-1). Additionally, tranylcypromine was structurally modified to enhance the effects of LSd1 inhibition in TBI. As a result, a tractable neuroprotective agent, BACE2-IN-1/tranylcypromine-based compound 4, was identified, showing potential to maintain Neuro-2a cell survival by alleviating mitochondrial damage after oxidative stress. Compound 4 also restored TBI-mediated inhibition of the cholesterol biosynthetic pathway (mevalonate pathway) and damage of redox metabolism, increasing neuroprotective effects. Furthermore, behavioral assays, including nest-building and cognitive performance tests, demonstrated significant improvement in mice post-TBI following treatment with compound 4. Taken together, the outcomes of this study validate the favorable effects of inhibiting LSd1 and beta-secretase in mitigating mitochondrial stress and promoting neurometabolic recovery in TBI. These findings pave the way for the development of rationally designed inhibitors as promising neuroprotective agents, potentially addressing unmet clinical needs in TBI treatment. © 2025 The Authors

关键词： Beta-secretase LSd1 Oxidative stress Sterol biosynthesis Tranylcypromine Traumatic brain injury

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The Bacterial Outer Membrane Vesicle-Cloaked Immunostimulatory Nanoplatform Reinvigorates T Cell Function and Reprograms Tumor Immunity

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ACS Nano 2025年 2025 May 20页

作者： Lin, Yu-Han Chen, Chia-Wei Chen, Mei-Yi Xu, Li Tian, Xuejiao Cheung, Siu-Hung Wu, Yen-Ling Siriwon, Natnaree Wu, Si-Han Mou, Kurt Yun Taiwan International Graduate Program in Molecular Medicine National Yang Ming Chiao Tung University and Academia Sinica Taipei 11529 Taiwan Graduate Institute of Nanomedicine and Medical Engineering Taipei Medical University Taipei 11031 Taiwan Institute of Biomedical Sciences Academia Sinica Taipei 11529 Taiwan Research Center for Applied Sciences Academia Sinica Taipei 11529 Taiwan Chakri Naruebodindra Medical Institute Faculty of Medicine Ramathibodi Hospital Mahidol University Samutprakarn 10540 Thailand International Ph.D. Program in Biomedical Engineering Taipei Medical University Taipei 11031 Taiwan Nano Science and Technology Program Taiwan International Graduate Program Academia Sinica Taipei 11529 Taiwan Department of Engineering and System Science National Tsing Hua University Hsinchu 30013 Taiwan

Bacterial outer membrane vesicles (OMVs) represent powerful immunoadjuvant nanocarriers with the capacity to reprogram the tumor microenvironment (TME) and activate immune responses. Here, we investigate a nanotherapeutic platform integrating immunostimulatory cytosine-phosphate-guanine oligodeoxynucleotides (CpG-OdNs, hereafter termed CpG) into mesoporous silica nanoparticles cloaked with OMVs (CpG@MSN-PEG/PEI@OMVs) for cancer immunotherapy. Systemic administration of these nanohybrids facilitates precise tumor targeting, induces antitumor cytokines such as IFNγ, and suppresses immunosuppressive cytokine TGF-β, reshaping the TME. Additionally, CpG@MSN-PEG/PEI@OMVs promote M1 macrophage polarization, dendritic cell maturation, and the generation of durable tumor-specific immune memory, resulting in pronounced tumor regression with minimal systemic toxicity. The platform demonstrates efficacy against metastatic and solid tumor models including 4T1 breast and MC38 colorectal cancers. Transcriptomic analyses reveal that CpG@MSN-PEG/PEI@OMVs enhance mitochondrial oxidative phosphorylation in T cells within tumor-draining lymph nodes, mitigating T cell exhaustion and restoring metabolic fitness. These results support the potential of CpG@MSN-PEG/PEI@OMVs as a modular nanoplatform to modulate innate and adaptive immunity in cancer immunotherapy. © 2025 The Authors. Published by American Chemical Society.

关键词： bacterial outer membrane vesicles mesoporous silica nanoparticles mitochondrial activity T cell exhaustion phenotypes tumor microenvironment

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Investigation of Short-Circuit Current density in Non-Fullerene-Based Ternary Organic Solar Cells by Incorporating Machine Learning Algorithms with Effective descriptors

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Solar RRL 2025年第10期9卷

作者： Lee, Min-Hsuan Chen, Ying-Chun Chang, Yi-Ming Hou, Bo Ph.D. Program in Biomedical Artificial Intelligence National Tsing Hua University Hsinchu Taiwan Institute of Environmental and Occupational Health Sciences School of Medicine National Yang-Ming Chiao Tung University Taipei Taiwan Institute of Environmental Engineering National Yang-Ming Chiao Tung University Hsinchu Taiwan Department of Mechanical Engineering National Taiwan University of Science and Technology Taipei Taiwan Raynergy Tek Incorporation Hsinchu Taiwan School of Physics and Astronomy Cardiff University Cardiff United Kingdom

Non-fullerene acceptor (NFA)-based ternary organic solar cells (OSCs) are emerging as promising devices for converting sunlight into electricity, contributing to environmental solutions. However, selecting the third component remains a significant challenge, as it plays a critical role in achieving high short-circuit current density (Jsc) in NFA-based ternary OSCs (comprising donors, acceptors, and the third component). Traditional trial-and-error experimental methods face substantial limitations, including high energy consumption, cost, and time demands, which may not be sufficient for investigating the quantitative relationships between material properties and Jsc in ternary OSCs. In this study, we examine the effects of the highest occupied molecular orbital–lowest unoccupied molecular orbital (HOMO–LUMO) energy gap (ΔHOMO and ΔLUMO) between different organic materials, considering these as effective molecular descriptors, on the primary photovoltaic parameter (Jsc) in NFA-based ternary OSCs. The eXtreme Gradient Boosting (XGBoost) algorithm yields reasonable predictions, with an R2 value of 0.76. Additionally, three NFA-based ternary OSCs are fabricated and characterized experimentally to validate the predictions made by the proposed model. Using three different NFA-based ternary OSCs as inputs, the model demonstrates good predictive accuracy for Jsc values. The proposed interpretable model and effective molecular descriptors offer a practical machine-learning approach for accelerating the development of NFA-based ternary OSCs with targeted Jsc values and can also be extended to other organic electronic applications. © 2025 Wiley-VCH GmbH.

关键词： Learning algorithms

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Advanced ZnFe₂O₄@f-CNF electrode: A robust electrochemical sensor for Tert-butyl hydroquinone detection in food and edible oil

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Food Chemistry 2025年 486卷 144648页

作者： Yemmi, Rajeshwari Swamy, B.E. Kumara Manjunath, Kumbar Mudakappa Yusuf, Kareem Aljuwayid, Ahmed M. Govindasamy, Mani 577451 India Division of Plant Breeding and Genetics Central Coffee Research Institute Karnataka Chikkamagaluru577117 India Department of Chemistry College of Science King Saud University Riyadh11451 Saudi Arabia International Ph.D. Program in Innovative Technology of Biomedical Engineering and Medical Devices Ming Chi University of Technology New Taipei City243303 Taiwan Research Center for Intelligence Medical Devices Ming Chi University of Technology New Taipei City243303 Taiwan Department of Chemistry Korea University Seoul Seongbuk-gu Korea Republic of

Fabrication of a binary electrocatalyst is expounded in this study, which is based on a biocompatible ZnFe2O4 nanoparticles that is adorned onto the functionalized carbon nanofiber (f-CNF) through a straightforward ultrasonication technique. This electrocatalyst is applied for the reliable quantification of the food additive Tert-Butyl Hydroquinone (TBHQ) from various food samples and products. The electrochemical performance of the ZnFe2O4@f-CNF composite is investigated using cyclic voltammetry and electrochemical impedance spectroscopy analysis. The structural features of the composite, characterized by X-ray diffraction, scanning electron microscopy and transmission electron microscopy which reveals its crystalline and porous attributes. Then electrochemical characteristics of the ZnFe2O4@f-CNF composite for TBHQ detection is evaluated employing cyclic voltammetry and differential pulse voltammetry methodologies. Notably, this composite demonstrates a remarkable low detection limit (LOd) of 0.026 μM with a good linear detection range, accompanied by a favorable sensitivity towards TBHQ. Lastly, the developed sensor system manifests a substantial recovery range for real sample analysis, suggesting its potential as a viable alternative to existing diagnostic tools for TBHQ detection. © 2025 Elsevier Ltd

关键词： Cyclic voltammetry

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