检索结果-内蒙古大学图书馆

CGMP Consortium:A Multicenter,Longitudinal Clinical Trial Plan for Constipation Multi-Omics and Precision Micro-Ecological Intervention Strategies

引用

engineering 2024年第12期43卷 17-21页

作者： Linlin Wang Tong Zhang Hongliang Tian Qiyi Chen Lianmin Chen Yuzheng Xue Gaojue Wu Yurong Tang Ning Li Qixiao Zhai Wei Chen State Key Laboratory of Food Science and Resources Jiangnan UniversityWuxi 214122China School of Food Science and Technology Jiangnan UniversityWuxi 214122China Institute of Gut Microbiota Research and Engineering Development Shanghai Tenth People's HospitalTongji University School of MedicineShanghai 200072China Cardiovascular Research Center The Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou Municipal HospitalGusu SchoolNanjing Medical UniversitySuzhou 215000China Department of Gastroenterology Affiliated Hospital of Jiangnan UniversityWuxi 214000China Department of Gastroenterology Jiangnan University Medical Center(Wuxi No2 People's Hospital)Wuxi 214000China Department of Gastroenterology Jiangsu Province Hospital(The First Affiliate Hospital of Nanjing Medical University)Wuxi 214122China National Engineering Research Center for Functional Food Jiangnan UniversityWuxi 214122China

*** functional constipation(FC),encompassing normal-transmission constipation(NTC),slow-transmission constipation(STC),obstructed defecation constipation,and mixed constipation(MC),is a common gastrointestinal disorde... 详细信息

关键词： Clinical constipation gastrointestinal

来源：评论

学校读者我要写书评

暂无评论

An Innovative Carbon Dots Polarity Probe Based on Intramolecular Charge-Transfer for Visual Monitoring of the Total Polar Materials in Frying Oil

SSRN

引用

SSRN 2024年

作者： Xu, Jiangbin Yang, Wei Liu, Yuanfa State Key Laboratory of Food Science and Resources School of Food Science and Technology National Engineering Research Center for Functional Food National Engineering Laboratory for Cereal Fermentation Technology Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province Jiangnan University 1800 Lihu Road Jiangsu Wuxi214122 China Research Institute 111 Baima Road Jiangsu Nanjing211200 China

The presence of Total Polar Materials (TPM) in edible oils is a crucial indicator for assessing oil quality. It is of paramount importance to develop a rapid and dependable technique for monitoring polarity in frying oil. Sensitive polarity responsive fluorescence carbon dots (F-CDs) were synthesized by using p-phenylenediamine as precursors and 2-formylphenylboronic acid pinacol ester (2-FAPE) as a post-modifier. The construction of the fluorescent probe F-CDs involved a strong intramolecular charge-transfer (ICT) mechanism, with 2-FAPE serving as the electron-withdrawing fluorophore and the π-conjugated structure acting as a potent electron-donating group. A strong linear relationship was observed between the emission wavelength and the TPM value of frying oil within a range of 11% to 30%. Notably, the fluorescence color of the probe transitioned from blue to yellow under UV light at 365 nm as the TMP value increased. This study expands the range of sensing applications for CDs in food safety. © 2024, The Authors. All rights reserved.

关键词： Fluorescence

来源：评论

学校读者我要写书评

暂无评论

Comparison of Digestion, Absorption, and Metabolism Characteristics of Phosphatidylcholines from Egg, Soy, and Krill in Vivo Using Lc-Mrm-Ms

SSRN

引用

SSRN 2024年

作者： Du, Runfeng Liu, Yanjun Ye, Zhan Zhang, Jian Li, Cailing Liu, Yuanfa State Key Laboratory of Food Science and Resources School of Food Science and Technology National Engineering Research Center for Functional Food National Engineering Laboratory for Cereal Fermentation Technology Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province Jiangnan University 1800 Lihu Road Jiangsu Wuxi214122 China Research Institute 111 Baima Road Jiangsu Nanjing211200 China

The acyl chain composition of dietary sources phosphatidylcholine (PC) is highly diverse. Here, the differences of 36 PCs and the major metabolites 10 LPCs species in mice small intestinal contents, jejunum, plasma, and colonic contents within 12h after administration of Egg-PC, Soy-PC, and Krill-PC were evaluated. Three PCs could be rapidly hydrolyzed to LPCs within 0.5h after reaching the small intestine, and then LPCs containing 16:0, 18:0, and 18:2 could be re-esterified to chylomicron PCs, and incorporated into blood. Specifically, Egg-PC administration increased plasma LPC 20:4 and PC16:0_20:4. Notably, the fraction of plasma PUFA_PUFA PCs such as PC 18:2_18:2 after administration of Soy-PC for 2 h increased 5-fold. Strikingly, plasma LPC20:5 and PCs containing 20:5 increased more than 20-fold after administration of krill-PC for 2h, but the level of PC20:5_20:5 was scarce. These results could helpful to efficiently utilize the nutritional functions of PCs with different acyl chains. © 2024, The Authors. All rights reserved.

关键词： Metabolites

来源：评论

学校读者我要写书评

暂无评论

New insights into the interactions between dark blue pigment from Vaccinium bracteatum Thunb leaves and digestive enzymes

引用

Food Bioscience 2022年第6期50卷 1856-1865页

作者： Mingcong Fan Zhengyu Bao Tingting Li Jiajia Zhao Yan Li Haifeng Qian Hui Zhang Zhiming Rao Li Wang School of Food Science and Technology State Key Laboratory of Food Science and TechnologyNational Engineering Research Center for Functional FoodJiangnan University1800 Lihu AvenueWuxi214122China Department of Food Science and Engineering College of Light Industry and Food EngineeringNanjing Forestry University159 Longpan RoadNanjing210037China College of Cooking Science and Technology Jiangsu College of TourismYangzhou225000China School of Biotechnology Jiangnan University1800 Lihu AvenueWuxi214122China

The dark blue pigment from Vaccinium bracteatum ***(VBTL)is a healthy ingredient for controlling postprandial blood glucose during the stage of dietary carbohydrate *** previous study has proved that the dark blue pigment has an inhibition effect on pancreaticα-***,the influence on other digestive enzymes(α-glucosidases,trypsin,andα-chymotrypsin)is still ***,this research evaluated the impact of this dark blue pigment on the three digestive enzymes during in-vitro *** effects of dark blue pigment on the activities and conformations of theα-glucosidase,trypsin,andα-chymotrypsin were confirmed by multi-spectroscopic techniques and molecular *** results showed that this pigment possessed a higher inhibition ability on theα-*** complexes of three enzymes and the pigment all resulted in the changes in fluorescence quenching and secondary structures of these ***,the interactions between two proteolytic enzymes and pigment slightly impacted their ***,molecular docking suggested that the complex betweenα-glucosidase and pigment formed hydrogen bonds and hydrophobic interactions in the substrate-binding *** findings provide creative insight into the VBTL dark blue pigment controlling postprandial hyperglycemia without side effects on the proteolytic enzymes.

关键词： Vaccinium bracteatum Thunb.leaf Dark blue pigment α-glucosidase Spectrophotometric assays Molecular docking

来源：评论

学校读者我要写书评

暂无评论

An Innovative Carbon Dots Polarity Probe Based on Intramolecular Charge-Transfer for Visual Monitoring of the Total Polar Materials in Frying Oil

SSRN

引用

SSRN 2024年

关键词： Fluorescence

来源：评论

学校读者我要写书评

暂无评论

D^(6h)Symmetric Radical Donor-Acceptor Nanographene Modulated Interfacial Carrier Transfer for High-Performance Perovskite Solar Cells

引用

CCS Chemistry 2023年第9期5卷 2159-2170页

作者： Can Wang Yifeng Gao Zhen-Lin Qiu Ping-Ping Sun Naoyuki Shibayama Zilong Zhang Qiu Xiong Fangbin Ren Shui-Yang Lien Lusheng Liang Jiaoxia Zhang Yuan-Zhi Tan Peng Gao CAS Key Laboratory of Design and Assembly of Functional Nanostructures Fujian Provincial Key Laboratory of NanomaterialsFujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhouFujian 350002 Laboratory for Advanced Functional Materials Xiamen Institute of Rare Earth MaterialsHaixi InstituteChinese Academy of SciencesXiamen 361021 University of Chinese Academy of Sciences Beijing 100049 School of Materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003 Collaborative Innovation Center of Chemistry for Energy Materials State Key Laboratory for Physical Chemistry of Solid SurfacesEngineering Research Center for Nano-Preparation Technology of Fujian ProvinceDepartment of ChemistryCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005 Department of Chemistry School of ScienceHainan UniversityHaikou 570228 Faculty of Biomedical Engineering Graduate School of EngineeringToin University of YokohamaYokohamaKanagawa 225-8503 Xiamen University of Technology Xiamen 361024

Imbalanced charge-carrier extraction remains an issue aggravating interfacial charge accumulation and *** hopping transport channels could accelerate the extraction of ***,we demonstrated an effective“bridging interface”strategy between the perovskite/2,2′,7,7′-tetrakis(N,N-di-pmethoxyphenylamine)-9,9′-spirobifluorene(spiro-OMeTAD)that modulates interfacial charge transfer and improves hole mobility using radical-containing donor-acceptor nanographenes(D-A NGs)possessing electron-deficient perchlorinated NGs and electron-rich aniline *** fully delocalized backbone of nanographene formed a conjugated bridge for intermolecular charge transfer and generated stable radical cations,verified by electron spin *** andπ-πstacking orientation of D-A NGs also provided advantageous hopping transport *** favorable charge transfer within D-A NGs,systematic explorations indicated a strong interface coupling and noticeable charge transfer across the D-A NGs and perovskite interface,where electrons would flow from D-A NGs to perovskite,and holes would flow from perovskite to D-A ***,the hole mobility of spiro-OMeTAD was also enhanced because the D-A NGs would diffuse into the spiro-OMeTAD *** a result,planar n-i-p perovskite solar cellsmodified byD-ANG-OMe/D-ANG-tBudeliveredchampion power conversion efficiencies(PCEs)of 23.25%and 23.51%,respectively.

关键词： perovskite solar cell radicals donor-acceptor nanographene hole mobility interfacial charge transfer

来源：评论

学校读者我要写书评

暂无评论

Polygonatum sibiricum polysaccharide extract relieves FB1-induced neurotoxicity by reducing oxidative stress and mitochondrial damage in Caenorhabditis elegans

引用

Food Bioscience 2022年第5期49卷 799-809页

作者： Xiaojuan Zhang Yongli Ye Jiadi Sun Yida Xu Yaoguang Huang Jia-Sheng Wang Lili Tang Jian Ji Bi-yan Chen Xiulan Sun State Key Laboratory of Food Science and Technology School of Food Science and TechnologyNational Engineering Research Center for Functional FoodSynergetic Innovation Center of Food Safety and Quality ControlJiangnan UniversityWuxiJiangsu214122PR China Department of Environmental Health Science College of Public HealthUniversity of GeorgiaAthensGAUSA Zhejiang HeTianXing Biotechnology Co.Ltd. TaizhouZhejiang318000PR China

Fumonisin B1(FB1)is a mycotoxin that is harmful to the nervous system;however,there is currently a lack of studies on plant compounds that alleviate the neurotoxicity of *** sibiricum polysaccharides exhibit neuroprotective effects,but it is unclear whether they protect against FB1-induced ***,Caenorhabditis elegans(***)was used to study the alleviation effects of *** polysaccharide extract(PSPE)preprotection on FB1-induced *** pretreatment improved the behavioral deficits and neuronal damage in FB1-induced *** addition,20-200μg/mL PSPE alleviated the oxidative damage in FB1-induced *** by regulating the levels of reactive oxygen species,antioxidant enzyme activities and gene *** studies have shown that PSPE pretreatment induced mitochondrial expression,increased ATP levels and mitochondrial membrane potential,and regulated mitochondrial oxidative phosphorylation and ***,the protective effects of PSPE against FB1-induced neurotoxicity might be closely related with the reduction of oxidative stress and the regulation of mitochondria.

关键词： Polygonatum sibiricum polysaccharide Extract Fumonisin B1 Caenorhabditis elegans Neurotoxicity Oxidative stress Mitochondria

来源：评论

学校读者我要写书评

暂无评论

Observation of Topological Transition in Floquet Non-Hermitian Skin Effects in Silicon Photonics

引用

Physical Review Letters 2024年第7期133卷 073803-073803页

作者： Zhiyuan Lin Wange Song Li-Wei Wang Haoran Xin Jiacheng Sun Shengjie Wu Chunyu Huang Shining Zhu Jian-Hua Jiang Tao Li National Laboratory of Solid State Microstructures Key Laboratory of Intelligent Optical Sensing and Manipulations Jiangsu Key Laboratory of Artificial Functional Materials School of Physics College of Engineering and Applied Sciences School of Physical Science and Technology & Collaborative Innovation Center of Suzhou Nano Science and Technology School of Biomedical Engineering Suzhou Institute for Advanced Research School of Physics

Non-Hermitian physics has greatly enriched our understanding of nonequilibrium phenomena and uncovered novel effects such as the non-Hermitian skin effect (NHSE) that has profoundly revolutionized the field. NHSE has been predicted in systems with nonreciprocal couplings which, however, are challenging to realize in experiments. Without nonreciprocal couplings, the NHSE can also emerge in systems with coexisting gauge fields and loss or gain (e.g., in Floquet non-Hermitian systems). However, such Floquet NHSE remains largely unexplored in experiments. Here, we realize the Floquet NHSEs in periodically modulated optical waveguides integrated on a silicon photonic platform. By engineering the artificial gauge fields induced by the periodical modulation, we observe various Floquet NHSE phases and unveil their rich topological transitions. Remarkably, we discover the transitions between the unipolar NHSE phases and an unconventional bipolar NHSE phase, which is accompanied by the directional reversal of the NHSEs. The underlying physics is revealed by the band winding in complex quasienergy space which undergoes a topology change from isolated loops with the same winding to linked loops with opposite windings. Our work unfolds a new route toward Floquet NHSEs originating from the interplay between gauge fields and dissipation effects, and thus offers fundamentally new ways for steering light and other waves.

关键词： Edge states Integrated optics Topological effects in photonic systems Floquet systems Non-Hermitian systems Waveguide arrays

来源：评论

学校读者我要写书评

暂无评论

Effect of highland barely germination on thermomechanical,rheological,and micro-structural properties of wheat-oat composite flour dough

引用

Food Bioscience 2023年第3期53卷 554-563页

作者： Waleed AL-Ansi Jalal Ahmed Fadhl Abdulmageed Bagash Abdullah Abduqader Al-Adeeb Amer Ali Mahdi Qais Ali Al-Maqtari Bilal Sajid Mushtaq Mingcong Fan Yan Li Haifeng Qian Li Wang School of Food Science and Technology State Key Laboratory of Food Science and TechnologyJiangnan University1800 Lihu AvenueWuxi214122China National Engineering Research Center for Functional Food Jiangnan University1800 Lihu AvenueWuxi214122China Department of Food Science and Nutrition Faculty of AgricultureFood and EnvironmentSana’a UniversitySana’aYemen School of Biotechnology Jiangnan University1800 Lihu AvenueWuxi214122China School of Food and Biological Engineering Jiangsu UniversityZhenjiang212013China Department of Biology Faculty of ScienceSana’a UniversitySana’aYemen

This study investigated the effects of highland barley’s germination time(24,48,and 72 h)on the thermomechanical,pasting,fermentation,dynamic rheological,molecular mobility,and protein structural properties of oat-wheat composite flour *** significantly reduced flour water absorption,freezable water,melting enthalpy,and increased protein weakening compared with native barley(NB)*** addition,germination decreased bound and immobilized water and increased the free water compared to the NB-composite flour dough samples,according to the results of a low-field nuclear magnetic resonance spectrometer(LF-NMR).Germination also increased the protein’s extractability and surface hydrophobicity while negatively impacting the starch-protein network;however,it decreased bread-specific *** for 24 h,on the other hand,had minor effects on dough and bread samples compared to 48 and 72 *** a result,germination for 24 h under controlled conditions could be used to improve the rheological qualities of highland barley and avoid the adverse rheological effects of the prolonged germination period.

关键词： Germination Mixolab Rheological properties Highland barley Molecular mobility

来源：评论

学校读者我要写书评

暂无评论

Toxicity and metabolic effect of combined deoxynivalenol,3-acetyldeoxy-nivalenol,and 15-acetyldeoxynivalenol on a Caco-2 cell model

引用

Food Bioscience 2023年第3期53卷 2224-2233页

作者： Yongli Ye Kaimin Wei Jian Ji Xiao Ning Jia-Sheng Wang Xiulan Sun State Key Laboratory of Food Science and Technology School of Food Science and TechnologyNational Engineering Research Center for Functional FoodSynergetic Innovation Center of Food Safety and Quality ControlJiangnan UniversityWuxiJiangsu214122PR China Yixing Institute of Food and Biotechnology Co. LtdYixing214200PR China Department of Environmental Health Science College of Public HealthUniversity of GeorgiaAthensGA30602USA Key Laboratory of Food Quality and Safety for State Market Regulation National Institute of Food and Drug ControlBeijing100050PR China

Deoxynivalenol(DON),3-acetyldeoxynivalenol(3-acetylDON),and 15-acetyldeoxynivalenol(15-acetylDON)are typical type-B trichothecenes produced by Fusarium commonly found in cereals *** on the combined toxicity of these mycotoxins remain *** this study,human colorectal adenocarcinoma Caco-2 cell line was used to analyze the individual and combined toxic effects,together with the potential cytotoxic mechanism,of DON,3-acetylDON,and *** exerted the highest inhibitory rate of cell viability,followed by 15-acetylDON and *** binary and ternary combinations exerted an antag-onistic effect on Caco-2 cells at IC50-IC90 treatment doses;meanwhile,3-acetylDON+15-acetylDON at low doses exhibited additive effects,and DON+15-acetylDON and DON+3-acetylDON+15-acetylDON showed synergistic *** apoptotic rate and reactive oxygen species level of DON+3-acetylDON were lower than those of DON *** Caco-2 cells were treated with trichothecenes individually or in combination,Bcl-2 was significantly down-regulated,and Bax,p53,and caspases genes were ***,DON and its acetylated derivatives disrupted amino acid metabolism and protein *** results indicate that the toxicological effects of trichothecene combinations varied depending on the type of combination and *** co-exposure of DON and its derivatives may induce apoptosis of Caco-2 cells by inhibiting protein synthesis,inducing oxidative stress,and regulating the level of apoptosis-related *** findings can provide new vision for proposing intervention strategies for co-exposure toxicity of DON and its acetylated derivatives.

关键词： Deoxynivalenol Trichothecene Combined toxicity Metabonomics

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：