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TPP-Based Microfluidic Chip Design and Fabrication Method for Optimized Nerve Cells Directed Growth

Cyborg and Bionic Systems 2024年第1期5卷 434-447页

作者： Menghua Liu Anping Wu Jiaxin Liu Yanfeng Zhao Xinyi Dong Tao Sun Qing Shi Huaping Wang Intelligent Robotics Institute School of Mechatronical EngineeringBeijing Institute of TechnologyBeijing 100081China School of Medical Technology Beijing Institute of TechnologyBeijing 100081China Beijing Advanced Innovation Center for Intelligent Robots and Systems Beijing Institute of TechnologyBeijing 100081China Key Laboratory of Biomimetic Robots and Systems(Beijing Institute of Technology) Ministry of EducationBeijing 100081China

Microfluidic chips offer high customizability and excellent biocompatibility,holding important promise for the precise control of biological growth at the ***,the microfluidic chips employed in the studies of regulating cell growth are typically fabricated through 2D *** approach partially restricts the diversity of cell growth platform designs and manufacturing *** paper presents a method for designing and manufacturing neural cell culture microfluidic chips(NCMC)using two-photon polymerization(TPP),where the discrete and directional cell growth is optimized through studying the associated geometric parameters of on-chip *** study involves simulations and discussions regarding the effects of different hatching distances on the mold surface topography and printing time in the Describe print preview module,which determines the appropriate printing accuracy corresponding to the desired mold *** the assistance of the 3D maskless lithography system,micron-level rapid printing of target molds with different dimensions were *** NCMC with different geometric parameters,COMSOL software was used to simulate the local flow velocity and shear stress characteristics within the ***-SY5Y cells were selected for directional differentiation experiments on NCMC with different geometric *** results demonstrate that the TPP-based manufacturing method efficiently constructs neural microfluidic chips with high precision,optimizing the discrete and directional cell *** anticipate that our method for designing and manufacturing NCMC will hold great promise in construction and application of microscale 3D drug models.

关键词： two photon polymerization regulating cell growth nerve cell culture microfluidic chip precise control biological growth microfluidic chips d photolithographythis tpp based microfluidic chip cell growth platform

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Hybrid AC/DC Collection and HVDC Transmission Topology for Large-scale Offshore Wind Farms

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CSEE Journal of Power and Energy Systems 2025年第3期11卷 949-959页

作者： Wang Xiang Rui Tu Mingyu Han Jinyu Wen School of Electrical and Electronic Engineering Huazhong University of Science and Technology Wuhan China State Key Laboratory of Advanced Electromagnetic Technology Huazhong University of Science and Technology Wuhan China Changzhou Power Supply Company of State Grid Jiangsu Electric Power Co. Ltd. Changzhou China

Conventional offshore wind integration systems use 33kV or 66kV AC cables to collect wind energy and employ high voltage direct current (HVDC) transmission technology to deliver wind power to onshore grids. This scheme suffers from high costs for collection systems and offshore platforms when the capacity of offshore wind farms increases. This paper proposes a hybrid AC/DC collection and HVDC transmission concept for the large-scale offshore wind integration system. Wind farms near the offshore converter platform are integrated using AC collection cables, while the remaining wind farms are integrated using DC collection cables. The AC and DC collection cables infeed to the offshore converter platform, which features a three-terminal hybrid AC/DC/DC hub. The system layout and operating principle of the hybrid AC/DC collection and HVDC transmission system are introduced in detail. The control strategy and parameter design of the hybrid AC/DC/DC hub are presented. An economic evaluation comparing conventional AC collection and HVDC transmission schemes is conducted. It is indicated that the proposed integration concept can reduce the operating power capacity and power loss of the offshore converter, enhancing the economic efficiency of the overall integration system. Finally, the effectiveness of the proposed integration technology is validated in a 2000MW offshore wind power integration system by PSCAD/EMTDC simulation analysis.

关键词： Wind farms HVDC transmission Voltage Topology Costs Wind power generation Propagation losses Wind energy integration Underwater cables Seaports

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Design of dispersive module for a 3D object shape detection device 2

Design of dispersive module for a 3D object shape detection ...

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2nd IEEE Asia-Pacific Conference on Image Processing, Electronics and Computers, IPEC 2021

作者： Liu, Ruoxu Xie, Zhenhao Zou, Kuaisheng Zhou, Jiankang Soochow University School of Optoelectronic Science and Engineering Suzhou China Key Laboratory of Advanced Optical Manufacturing Technology of Jiangsu Province Key Laboratory of Modern Optical Technology of Ministry of Education Suzhou China

ISBN: (纸本)9781728190181

Confocal line spectroscopy is proposed for obtaining the three-dimensional shape detection of microscopic objects. An off-axis spectral confocal technology composed of TIR lens, PGP beam splitter and cylindrical lens. The design results show that the PGP dispersive device achieves the linearity of dispersion, and the focal plane formed by this scheme has a working distance of 6.92mm on the z-axis, corresponding to the wavelength range of 450nm-700nm, that is, 27.68 mu m/nm (1nm wavelength is corresponding to 27.68 microns);At the same time, the focal plane is 20mm long and 6.92mm deep, with the one-dimensional movement of the object, the three-dimensional shape information of the object can be obtained. © 2021 IEEE.

关键词： Object detection

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Study on refractive index distribution measurement of self-focusing lens with mach-zehnder interferometry 2

Study on refractive index distribution measurement of self-f...

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2nd IEEE Asia-Pacific Conference on Image Processing, Electronics and Computers, IPEC 2021

作者： Sun, Peng Xu, Feng Zou, Kuaisheng Ma, Suodong Soochow University School of Optoelectronic Science and Engineering Suzhou China Key Laboratory of Advanced Optical Manufacturing Technology of Jiangsu Province Key Laboratory of Modern Optical Technology of Ministry of Education Suzhou China

ISBN: (纸本)9781728190181

In this paper, a Mach-Zehnder Interferometry is designed and setup to measure the refractive index of a self-focusing lens. Interference fringe patterns with different ion exchange degrees are investigated and simulated at first. Experimental interference fringe patterns are collected and analyzed by Matlab. The refractive index distribution curve of the self-focusing lens is finally obtained to easily assess the ion exchange status. © 2021 IEEE.

关键词： Ion exchange

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“Three‐in‐one”strategy:Heat regulation and conversion enhancement of a multifunctional separator for safer lithium-sulfur batteries

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Carbon Energy 2023年第11期5卷 54-67页

作者： Kaiping Zhu Luhe Li Pan Xue Jun Pu Liyun Wu Gengde Guo Ran Wang Ye Zhang Huisheng Peng Guo Hong Qiang Zhang Yagang Yao National Laboratory of Solid State Microstructures College of Engineering and Applied SciencesJiangsu Key Laboratory of Artificial Functional MaterialsCollaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjingChina Key Laboratory of Functional Molecular Solids Ministry of EducationCollege of Chemistry and Materials ScienceAnhui Normal UniversityWuhuChina State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceLaboratory of Advanced MaterialsFudan UniversityShanghaiChina Department of Materials Science and Engineering College of EngineeringCity University of Hong KongHong KongChina Beijing Key Laboratory of Green Chemical Reaction Engineering and Technology Department of Chemical EngineeringTsinghua UniversityBeijingChina

The safety problems encountered with lithium–sulfur batteries(LSBs)hinder their development for practical ***,a highly thermally conductive separator was constructed by cross‐weaving super‐aligned carbon nanotubes(SA‐C)on super‐aligned boron nitride@carbon nanotubes(SA‐BC)to create a composite film(SA‐BC/SA‐C).This separator was used to fabricate safe LSBs with improved electrochemical *** highly aligned separator structure created a uniform thermal field that could rapidly dissipate heat accumulated during continuous operation due to internal resistance,which prevented the development of extremely high *** array of boron nitride nanosheets endowed the composite separator with a large number of adsorption sites,while the highly graphitized carbon nanotube skeleton accelerated the catalytic conversion of high‐valence polysulfides into low‐valence *** arrayed molecular brush design enabled the regulation of local current density and ion flux,and considerably alleviated the growth of lithium dendrites,thus promoting the smooth deposition of Li ***,a battery constructed with the SA‐BC/SA‐C separator showed a good discharge capacity of 685.2 mAh g−1 over 300 cycles(a capacity decay of 0.026%per cycle)at 2 C and 60°***“three‐in‐one”multifunctional separator design strategy constitutes a new path forward for overcoming the safety problems of LSBs.

关键词： conversion enhancement heat regulation high safety lithium-sulfur batteries multifunctional separator

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Wideband chaos generation using a VCSEL with intensity modulation optical injection for random number generation

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Science China(Information Sciences) 2024年第6期67卷 457-458页

作者： Yu HUANG Shuangquan GU Yuhang FENG Yigong YANG Shuiying XIANG Pei ZHOU Nianqiang LI School of Optoelectronic Science and Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow University State Key Laboratory of Integrated Service Networks Xidian University Key Lab of Advanced Optical Manufacturing Technologies of Jiangsu Province & Key Lab of Modern Optical Technologies of Education Ministry of China Soochow University

Physical random numbers have been widely used in modern network society,such as the generation of cryptographic keys for classical and quantum cryptography systems[1].Among the many sources of physical entropy,chaotic semiconductor lasers have attracted wide attention due to their desired characteristics including larger bandwidth,low cost,and monolithic integration[2].

关键词： Optical signal processing

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Microstructure and high-temperature tensile property of TiAl alloy produced by selective electron beam melting

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Rare Metals 2021年第12期40卷 3635-3644页

作者： Hang-Yu Yue Hui Peng Yong-Jun Su Xiao-Peng Wang Yu-Yong Chen School of Materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China Key Laboratory of High-Temperature Structural Materials and Coatings Technology Ministry of Industry and Information TechnologyBeihang UniversityBeijing 100191China School of Materials Science and Engineering Beihang UniversityBeijing 100191China Department of Mechanics College of EngineeringLishui UniversityLishui 323000China State Key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyHarbin 150001China

The microstructure and high-temperature tensile property of a Ti-47Al-2Cr-2 Nb alloy fabricated via selective electron beam melting(SEBM) with hatch spacings of 85,100,and 115 μm were systematically *** the hatch spacing increased from 85 to 115 μm,the microstructure comprising the horizontal cross section changed from coarse lamellar(y/B2) colonies to an inhomogeneous structure and the grain morphology transformed from elongated grains to inhomogeneous and equiaxed grains along the building direction of the vertical cross *** boundary population of the SEBMproduced TiAl alloy samples was dominated by high-angle grain boundaries(≥ 15°),and the volume fraction of these boundaries decreased with hatch spacing ***,the as-built TiAl alloy sample produced under a spacing of 100 μm exhibited the highest room-and elevated-temperature tensile strengths,with the ultimate tensile strength at room temperature(642 MPa) increasing to 674 MPa at 700 ℃.Furthermore,the mechanism of anomalous strengthening at 700 ℃ was discussed in detail.

关键词： Selective electron beam melting TiAl alloy Hatch spacing Microstructure Tensile property

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Ultra-low temperature anodic bonding of silicon and glass based on nano-gap dielectric barrier discharge

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Journal of Central South University 2021年第2期28卷 351-360页

作者： YAO Fu-rong PAN Ming-qiang ZHU Zong-jian LIU Ji-zhu WANG Yang-jun College of Mechatronics Engineering&Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow UniversitySuzhou 215123China Jiangsu Key Laboratory for Advanced Robotics Technology Soochow UniversitySuzhou 215123China Robotics and Microsystems Center Soochow UniversitySuzhou 215123China

The article improves the process of dielectric barrier discharge(DBD)activated anode *** treated surface was characterized by the hydrophilic surface *** results showed that the hydrophilic angle was significantly reduced under nano-gap conditions and the optimal discharge voltage was 2 ***,the anodic bonding and dielectric barrier discharge activated bonding were performed in comparison experiments,and the bonding strength was characterized by tensile failure *** results showed that the bonding strength was higher under the nano-gap dielectric barrier *** process completed 110°C ultra-low temperature anodic bonding and the bonding strength reached 2 ***,the mechanism of promoting bonding after activation is also discussed.

关键词： dielectric barrier discharge anodic bonding ultra-low temperature

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Design of dispersive objective lens of spectral confocal displacement sensor 2

Design of dispersive objective lens of spectral confocal dis...

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2nd IEEE Asia-Pacific Conference on Image Processing, Electronics and Computers, IPEC 2021

作者： Xie, Zhenhao Liu, Ruoxu Zou, Kuaisheng Zhou, Jiankang Soochow University School of Optoelectronic Science and Engineering Suzhou China Key Laboratory of Advanced Optical Manufacturing Technology of Jiangsu Province Key Laboratory of Modern Optical Technology of Ministry of Education Suzhou China

ISBN: (纸本)9781728190181

According to the working principle of the spectral confocal displacement sensor, four kinds of glass materials SKIO, H-ZLAF52A, N-LAK34 and SFL6 for dispersive lens are selected. 4 single lenses and one doublet lens are components of the initial structure of the linear dispersion objective lens. Optical design software is used to optimize the tolerance of the initial structure of the dispersive objective lens. The results show that the spot diagram of each wavelength is much smaller than the Airy disk. in the wavelength range of 450-700nm, the measurement range of the dispersive objective lens can reach 3.454 mm, and the linear determination coefficient R2 between the axial dispersion diatance and the wavelength is 0.972. © 2021 IEEE.

关键词： Dispersion (waves)

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Biplane Transrectal Ultrasound Probe Calibration using Dual-arm Robotic System with Multi-DOF End-effectors

Biplane Transrectal Ultrasound Probe Calibration using Dual-...

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IEEE/ASME (AIM) International Conference on advanced Intelligent Mechatronics

作者： Jing Xiong Qiangyun Li Faizan Ahmad Changfu Xu Hao Deng Zeyang Xia Medical Robotics and Minimally Invasive Surgical Devices Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen China Soft Robotics Research Center Shenzhen Institute of Advanced Technology University of Chinese Academy of Sciences Shenzhen China Soft Robotics Research Center Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen China Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced Technology CAS Shenzhen China

Transrectal Ultrasound (TRUS)-guided dual-arm robotic needle insertion system has improved clinical diagnosis treatment for biopsy and brachytherapy. It provides a highly precise and flexible method for inserting surgical needles. In the existing system, both the probe and needle are fixed to the robot’s end flange, which prevents the rotation and translation of the TRUS probe and needle from enabling multi-angle scanning and flexible needle insertion. In our previous work, we developed a dual-arm robotic needle insertion system with multi-degree-of-freedom (DOF) end-effectors to address the aforementioned issues. The calibration accuracy of the system directly determines the system’s effectiveness. However, existing calibration schemes are challenging to complete the calibration of the dual-arm robotic needle insertion system with multi-DOF end-effectors. Therefore, this paper presents a biplane TRUS probe calibration using dual-arm robotic needle insertion system with multi-DOF end-effectors. In the proposed approach, the kinematic of the multi-DOF probe and needle are first modeled to obtain the calibration parameters. Then the multi-DOF needle and probe are calibrated as the biplane TRUS image, which can be used to track the different motion states of the probe and needle. Finally, the experimental results are obtained and validated on the TRUS-guided dual-arm robotic needle insertion system. The results showed that the calibration accuracy of the overall system is 0.80±0.23 mm, which meets the clinical requirements.

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