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13th International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering, QR2MSE 2023

作者： Guo, Yu Ding, Taotao Jiangsu XCMG State Key Laboratory Technology Co. Ltd. Xuzhou China State Key Laboratory of Intelligent Manufacturing of Advanced Construction Machinery Xuzhou China Collage of Aerospace Science and Engineering National University of Defence technology Changsha China

ISBN: (纸本)9781839539848

The data deficiency is a universal phenomenon in excavator service life evaluation with classical probabilistic method. In order to solve the problem of small sample in excavator life evaluation, all kinds of storage information in the development process is fully utilized. In this paper, the evidence theory is used to integrate the main and objective information such as field test, laboratory test and expert comprehensive evaluation of each engine component. Therefore, the identification framework of excavator life and the basic probability assignment (BPA) calculation method based on the evidence network (EN) model are established. This method is used to evaluate the life of an excavator. The results show that the method is accurate and the estimated life of the excavator reaches the first maintenance cycle. The proposed method can make full use of all kinds of service life data in development, and is expected to provide a new technical approach for excavator service life evaluation with insufficient information. © The Institution of Engineering & technology 2023.

关键词： Excavators

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Mn‐doped CeO2 derived from Ce-MOF porous nanoribbons as highly active catalysts for the synthesis of dimethyl carbonate from CO2 and methanol

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Environmental Science and Pollution Research 2024年第35期31卷 47911-47922页

作者： Wang, Fei Jin, Yulong Xue, Yun Yu, Shuihang Liu, Na Ma, Qingxiang Xu, Jie Xue, Bing Wei, Xuejiao Jiangsu Province Key Laboratory of Fine Petrochemical Engineering Advanced Catalysis and Green Manufacturing Collaborative Innovation Center School of Petrochemical and Engineering Changzhou University Changzhou213164 China State Key Laboratory of High-Efficiency Coal Utilization and Green Chemical Engineering College of Chemistry and Chemical Engineering Ningxia University Yinchuan750021 China School of Chemical Engineering and Materials Changzhou Institute of Technology Changzhou213164 China

It is desirable but challenging to develop highly-efficient catalysts for the direct synthesis of dimethyl carbonate (DMC) from methanol and CO2. The vacancy-mediated incorporation of heteroatom into surface reconstruction is an efficient method of defect engineering for enhancing the catalytic properties. In this work, manganese-doped cerium oxide porous nanoribbons (Mn/CeO2-BTC) were prepared derived from a Ce-BTC by a sacrificial template approach. It is found that the catalytic activity of Mn/CeO2-BTC catalysts can be readily controlled by varying the amount of Mn dopants and the as-synthesized 0.1-Mn/CeO2-BTC exhibited an outstanding activity for the synthesis of DMC from CO2 and methanol, which reached a high DMC yield (6.53 mmolDMC/gcat.) without any dehydrating agents. Based on characterization results, the enhanced performance may be attributed to the defective structures caused by Mn doping and the porous nanoribbons of the CeO2 crystals, which provide more surface oxygen vacancies and acidic-basic sites, favoring adsorption and activation of CO2 and methanol. © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024.

关键词： Oxygen vacancies

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Motion Analysis of Magnetically Controlled Halbach Array

Motion Analysis of Magnetically Controlled Halbach Array

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2023 IEEE International Conference on Real-Time Computing and robotics, RCAR 2023

作者： Li, Yulu Shang, Wanfeng Huang, Wenqiang Liu, Xiaofei Wu, Xinyu South University of Science and Technology of China Shenzhen518055 China Chinese Academy of Sciences Shenzhen Institute of Advanced Technology Shenzhen518055 China Chinese Academy of Sciences Guangdong Provincial Key Laboratory of Robotics and Intelligent System Shenzhen Institute of Advanced Technology Shenzhen518055 China

ISBN: (纸本)9798350327182

Magnetic control technology is increasingly used in various fields to achieve more accurate wireless control. Different magnetic field arrangement modes can be selected for control according to different scenes. To acquiring the high maneuver of magnetic actuator and good application adaptability, Permanent Magnet Halbach array (PMHA) is a good choice as a potential robotic actuator. This paper presents the PMHA has more maneuverability and magnetic intensity than single polar magnets. FEM simulations and experiments are made to analyze the static and dynamic performances. Under the control of an external permanent magnet (EPM), the PMHA can achieve two kinds of rotation around different axises except for linear motion along with six arises. The experiments validate PMHA has the multi-mode motion performances and higher magnetic intensity per volume. The result provides its potential application as robotic actuator. © 2023 IEEE.

关键词： Permanent magnets

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Temperature-sensitive and solvent-resistance hydrogel sensor for ambulatory signal acquisition in“moist/hot environment”

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Nano Research 2023年第7期16卷 10348-10357页

作者： Xinyu Qu Hanjun Sun Xiaolong Kan Bing Lei Jinjun Shao Qian Wang Wenjun Wang Zhenhua Ni Xiaochen Dong Key Laboratory of Flexible Electronics(KLOFE)&Institute of Advanced Materials(IAM) School of Physical and Mathematical SciencesNanjing Tech University(NanjingTech)Nanjing 211816China School of Physical Science and Information Technology Liaocheng UniversityLiaocheng 252059China School of Physics and Key Laboratory of MEMS of the Ministry of Education Southeast UniversityNanjing 211189China School of Chemistry&Materials Science Jiangsu Normal UniversityXuzhou 221116China

To realize continuously and stably work in a“moist/hot environment”,flexible electronics with excellent humid resistance,antiswelling,and detection sensitivity are ***,a solvent-resistant and temperature-ultrasensitive hydrogel sensor was prepared by combining MXene and quaternized chitosan(QCS)with the binary polymer *** strong electrostatic interaction between the QCS chain and the poly(acrylic acid)(PAA)network endows the hydrogel stability against solvent erosion,high temperature,and high *** strong dynamic interaction between MXene and polymer matrix significantly improves the mechanical properties and sensing(strain and temperature)sensitivity of the *** hydrogel strain sensor exhibits a high gauge factor(5.53),temperature/humidity tolerance(equilibrium swelling ratio of 2.5%at 80℃),and excellent cycle stability,which could achieve a remote and accurate perception of complex human motion and environment fluctuation under aquatic ***,the hydrogel sensor exhibits impressive thermal response sensitivity(-3.183%/℃),ultrashort response time(<2.53 s),and a low detection limit(<0.5℃)in a wide temperature range,which is applied as an indicator of the body surface and ambient *** short,this study broadens the application scenarios of hydrogels in persistent extreme thermal and wet environments.

关键词： flexible electronics hydrogel sensor solvent-resistance underwater application

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Superparamagnetic iron oxide nanoparticle regulates microbiota-gut-inner ear axis for hearing protection

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National Science Review 2024年第6期11卷 273-284页

作者： Zhanhang Guo Yunhao Wu Bo Chen Mengdie Kong Peng Xie Yan Li Dongfang Liu Renjie Chai Ning Gu Jiangsu Key Laboratory for Biomaterials and Devices School of Biological Science and Medical EngineeringSoutheast University Medical Science and Technology Innovation Center Shandong First Medical University &Shandong Academy of Medical Sciences State Key Laboratory of Digital Medical Engineering Department of Otolaryngology Head and Neck SurgeryZhongda HospitalSchool of Life Sciences and Technology School of Medicine Advanced Institute for Life and Health Jiangsu Province High-Tech Key Laboratory for Bio-Medical ResearchSoutheast University Institute of Materials Science and Devices School of Materials Science and Engineering Suzhou University of Science and Technology Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging &Interventional Radiology & Vascular Surgery Department of Radiology Medical School Zhongda Hospital Southeast University Co-Innovation Center of Neuroregeneration Nantong University School of Medical Technology Institute of Engineering MedicineBeijing Institute of Technology Department of Otolaryngology Head and Neck Surgery Sichuan Provincial People's HospitalUniversity of Electronic Science and Technology of China Institute for Stem Cell and Regeneration Chinese Academy of Sciences Southeast university Shenzhen research institute Cardiovascular Disease Research Center Nanjing Drum Tower Hospital Affiliated Hospital of Medical School Medical School Nanjing University

Noise-induced hearing loss(NIHL) is a highly prevalent form of sensorineural hearing damage that has significant negative effects on individuals of all ages and there are no effective drugs approved by the US Food and Drug Administration. In this study, we unveil the potential of superparamagnetic iron oxide nanoparticle assembly(SPIOCA) to reshape the dysbiosis of gut microbiota for treating NIHL. This modulation inhibits intestinal inflammation and oxidative stress responses, protecting the integrity of the intestinal barrier. Consequently, it reduces the transportation of pathogens and inflammatory factors from the bloodstream to the cochlea. Additionally, gut microbiota-modulated SPIOCA-induced metabolic reprogramming in the gut–inner ear axis mainly depends on the regulation of the sphingolipid metabolic pathway, which further contributes to the restoration of hearing function. Our study confirms the role of the microbiota–gut–inner ear axis in NIHL and provides a novel alternative for the treatment of NIHL and other microbiota dysbiosis-related diseases.

关键词： superparamagnetic iron oxide nanoparticle hearing loss gut microbiota inflammation sphingolipid metabolism microbiota–gut–inner ear axis

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The single-cell transcriptomic landscape of the topological differences in mammalian auditory receptors

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Science China(Life Sciences) 2024年第11期67卷 2398-2410页

作者： Xiangyu Ma Xin Chen Yuwei Che Siyao Zhu Xinlin Wang Shan Gao Jiheng Wu Fanliang Kong Cheng Cheng Yunhao Wu Jiamin Guo Jieyu Qi Renjie Chai State Key Laboratory of Bioelectronics Department of Otolaryngology Head and Neck SurgeryZhongda HospitalSchool of Life Sciences and TechnologyAdvanced Institute for Life and HealthJiangsu Province High-Tech Key Laboratory for Bio-Medical ResearchSoutheast UniversityNanjing 210096China School of Engineering Vanderbilt UniversityNashville 37240USA Department of Otolaryngology-Head and Neck Surgery Affiliated Drum Tower Hospital of Nanjing University Medical SchoolJiangsu Provincial Key Medical Discipline(Laboratory)Nanjing 210096China Research Institute of Otorhinolaryngology Nanjing 210096China Department of Neurology Aerospace Center HospitalSchool of Life SciencesBeijing Institute of TechnologyBeijing 100081China Advanced Technology Research Institute Beijing Institute of TechnologyBeijing 100081China Co-innovation Center of Neuroregeneration Nantong UniversityNantong 226001China Department of Otolaryngology Head and Neck Surgery Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610072China Southeast University Shenzhen Research Institute Shenzhen 518063China

Mammalian hair cells(HCs)are arranged spirally along the cochlear axis and correspond to different frequency *** as primary sound detectors,HCs spatially segregate component frequencies into a topographical *** display significant diversity in anatomical and physiological characteristics,yet little is known about the organization of the cochleotopic map of HCs or the molecules involved in this *** single-cell RNA sequencing,we determined the distinct molecular profiles of inner hair cells and outer hair cells,and we identified numerous position-dependent genes that were expressed as *** identified genes such as Ptn,Rxra,and Nfe2l2 were found to be associated with *** employed the SCENIC algorithm to predict the transcription factors that potentially shape these tonotopic ***,we confirmed that Nfe2l2,a tonotopy-related transcription factor,is critical in mice for sensing low-tomedium sound frequencies in *** analysis of cell-cell communication revealed potential receptor-ligand networks linking inner hair cells to spiral ganglion neurons,including pathways such as BDNF-Ntrk and PTN-Scd4,which likely play essential roles in tonotopic ***,these findings suggest that molecular gradients serve as the organizing principle for maintaining the selection of sound frequencies by HCs.

关键词： tonotopic axis hair cell auditory receptor scRNA-seq

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Rhenium-boosted electrocatalytic activity and durability of pyrolytic IrO_(2)for acidic oxygen evolution

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Rare Metals 2024年第12期43卷 6758-6764页

作者： Hong-Wei Lv Hong-Bin Zhao Xin-Yuan Peng Zhi-Guo Ye Quan-Bo Huang Xue-Tao Yuan Duo-Sheng Li Zhong Jin School of Materials Science and Engineering Nanchang Hangkong UniversityNanchang330063China General Research Institute for Nonferrous Metals Beijing100088China China GRINM Group Co. Ltd.Beijing100088China National Engineering Research Center for Environment-Friendly Metallurgy in Producing Premium Non-Ferrous Metals GRINM Resources and Environment Tech.Co.Ltd.Beijing Engineering Research Center of Strategic Nonferrous Metals Green Manufacturing TechnologyBeijing100088China State Key Laboratory of Coordination Chemistry MOE Key Laboratory of Mesoscopic ChemistryMOE Key Laboratory of High Performance Polymer Materials and TechnologyJiangsu Key Laboratory of Advanced Organic MaterialsSchool of Chemistry and Chemical EngineeringNanjing UniversityNanjing210023China

IrO2,renowned for its exceptional stability in acidic media,suffers from limited electrocatalytic activity for the oxygen evolution reaction(OER).To enhance the intrinsic OER activity while preserving ultrahigh stability,here we report the synthesis of rhenium(Re)heteroatom incorporated pyrolytic IrO_(2),using the pyrolytic decomposition method.

关键词： method acidic stability

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3D printed multicore fiber-tip discriminative sensor for magnetic field and temperature measurements

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Light(advanced Manufacturing) 2024年第1期5卷 82-92页

作者： Cong Xiong Caoyuan Wang Ruowei Yu Wei Ji Yu Qin Yichun Shen Wei Chen Ai-Qun Liu Limin Xiao Advanced Fiber Devices and Systems Group Key Laboratory of Micro and Nano Photonic Structures(MoE)Key Laboratory for Information Science of Electromagnetic Waves(MoE)Shanghai Engineering Research Center of Ultra-Precision Optical ManufacturingSchool of Information Science and TechnologyFudan UniversityShanghaiChina Zhongtian Technology Advanced Materials Co. Ltd.NantongJiangsuChina Key laboratory of Specialty Fiber Optics and Optical Access Networks Joint International Research Laboratory of Specialty Fiber Optics and Advanced CommunicationShanghai University.ShanghaiChina Department of Electrical and Electronic Engineering The Hong Kong Polytechnic UniversityHong KongChina

Miniaturized fiber-optic magnetic field sensors have attracted considerable interest owing to their superiorities in anti-electromagnetic interference and ***,the intrinsic thermodynamic properties of the material make temperature cross-sensitivity a challenging problem in terms of sensing accuracy and *** this study,an ultracompact multicore fiber(MCF)tip sensor was designed to discriminatively measure the magnetic field and temperature,which was subsequently evaluated *** novel 3D printed sensing component consists of a bowl-shaped microcantilever and a polymer microfluid-infiltrated microcavity on the end-facet of an MCF,acting as two miniaturized Fabry-Perot *** magnetic sensitivity of the microcantilever was implemented by incorporating an iron micro ball into the microcantilever,and the microfluid-infiltrated microcavity enhanced the capability of highly sensitive temperature *** this tiny fiber-facet device in the two channels of an MCF allows discriminative measurements of the magnetic field and temperature by determining the sensitivity coefficient matrix of two *** device exhibited a high magnetic field intensity sensitivity,approximately 1805.6 pm/mT with a fast response time of~213 ms and a high temperature sensitivity of 160.3 pm/℃.Moreover,the sensor had a low condition number of 11.28,indicating high reliability in two-parameter *** proposed 3D printed MCF-tip probes,which detect multiple signals through multiple channels within a single fiber,can provide an ultracompact,sensitive,and reliable scheme for discriminative *** bowl-shaped microcantilever also provides a useful platform for incorporating microstructures with functional materials,extending multi-parameter sensing scenarios and promoting the application of MCFs.

关键词： Two-photon polymerization Multicore fiber-tip sensor Magnetic field sensing Discriminative sensing

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Vitamin D binding protein in psychiatric and neurological disorders:Implications for diagnosis and treatment

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Genes & Diseases 2024年第5期11卷 324-334页

作者： Ling Li Bing Han Yan Kong Gaojia Zhang Zhijun Zhang Research Institution of Neuropsychiatry School of MedicineSoutheast UniversityNanjingJiangsu 210009China Department of Neurology Affiliated Zhongda HospitalNanjingJiangsu 210009China Department of Pharmacology Jiangsu Provincial Key Laboratory of Critical Care MedicineSchool of MedicineSoutheast UniversityNanjingJiangsu 210009China Department of Biochemistry and Molecular Biology School of MedicineSoutheast UniversityNanjingJiangsu 210009China Brain Cognition and Brain Disease Institute Department of Mental Health and Public HealthFaculty of Life and Health SciencesShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong 518055China

Vitamin D binding protein(VDBP)serves as a key transporter protein responsible for binding and delivering vitamin D and its metabolites to target *** plays a crucial part in the inflammatory reaction following tissue damage and is engaged in actin *** research has shed light on its potential role in various diseases,leading to a growing interest in understanding the implications of VDBP in psychiatric and neurological *** purpose of this review was to provide a summary of the existing understanding regarding the involvement of VDBP in neurological and psychiatric *** examining the intricate interplay between VDBP and these disorders,this review contributes to a deeper understanding of underlying mechanisms and potential therapeutic *** gained from the study of VDBP could pave the way for novel strategies in the diagnosis,prognosis,and treatment of psychiatric and neurological disorders.

关键词： Neurological disorder Polymorphism Psychiatric disorder Structure Vitamin D binding protein

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Landing Area Prediction in Complex Terrains for Walking-assisted Lower-limb Exoskeleton Robot

Landing Area Prediction in Complex Terrains for Walking-assi...

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2023 International Conference on Biomimetic Intelligence and robotics

作者： Liu, Yuexun Liu, Du-Xin Ma, Yue Guo, Sheng Wu, Xinyu Robotics Research Center School of Mechanical Electronic and Control Engineering Beijing Jiaotong University Beijing100044 China Guangdong Provincial Key Laboratory of Robotics and Intelligent System Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen518055 China

With the expansion of application scenarios, the walking-assisted lower-limb exoskeleton robot urgently needs to improve its walking ability in complex terrains. However, due to the lack of environmental understanding ability and decision-making ability, the exoskeleton can not meet the need of people with lower-limb disability in complex terrains. To improve the walking abillity, this paper proposes a method of predicting the landing area in complex terrains for walking-assisted lower-limb exoskeleton robot. Multiple sensors were used to obtain the terrain information, step length, and stride length of human walking, and a multi-type input convolutional network was built to establish the mapping relationship to learn the decision-making mechanism of human standing in a complex environment. The result shows that the established network effectively predicts the landing area. Under the condition of full training, the predicted position deviation of the landing area is controlled within 6%, and the prediction rationality of the landing area can reach 90%. © 2023 The Authors. Published by Elsevier B.V.

关键词： Decision making

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