检索结果-内蒙古大学图书馆

Effects of ultrahigh pressure extraction on yield and antioxidant activity of chlorogenic acid and cynaroside extracted from flower buds of Lonicera japonica

引用

Chinese Journal of Natural Medicines 2015年第6期13卷 445-453页

作者： HU Wen GUO Ting JIANG Wen-Jun DONG Guang-Li CHEN Da-Wei YANG Shi-Lin LI He-Ran College of Pharmacy Soochow University Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application Department of Polymer Science and Engineering College of Chemistry Chemical Engineering and Materials Science Soochow University Guiding Long Da Honeysuckle Technology Co. Ltd.

The present study was designed to establish and optimize a new method for extracting chlorogenic acid and cynaroside from Lonicera japonica Thunb. through orthogonal experimental designl. A new ultrahigh pressure extraction （UPE） technology was applied to extract chlorogenic acid and cynaroside from L. japonica. The influential factors, including solvent type, ethanol concentration, extraction pressure, time, and temperature, and the solid/liquid ratio, have been studied to optimize the extraction process, The optimal conditions for the UPE were developed by quantitative analysis of the extraction products by HPLC-DAD in comparison with standard samples. In addition, the microstructures of the medicinal materials before and after extraction were studied by scanning electron microscopy （SEM）. Furthermore, the extraction efficiency of different extraction methods and the 2, 2-diphenyl-1-picrylhydrazyl （DPPH） radical scavenging activities of the extracts were investigated. The optimal conditions for extracting chlorogenic acid and cynaroside were as follows： ethanol concentration, 60%; extraction pressure, 400 MPa; extraction time, 2 rain; extraction temperature, 30 ℃; and the solid/liquid ratio, 1 ： 50. Under these conditions, the yields of chlorogenic acid and cynaroside were raised to 4.863% and 0.080%, respectively. Compared with other extraction methods, such as heat reflux extraction （HRE）, ultrasonic extraction （UE）, and Sohxlet extraction （SE）, the UPE method showed several advantages, including higher extraction yield, shorter extraction time, lower energy consumption, and higher purity of the extracts. This study could help better utilize L. japonica flower buds as a readily accessible source of natural antioxidants in food and pharmaceutical industries.

关键词： Lonicerajaponica Thunb. Ultrahigh pressure extraction Chlorogenic acid Cynaroside Antioxidant activity

来源：评论

学校读者我要写书评

暂无评论

design and Development of functional Biodegradable Polycarbonates and Polypeptides for Emerging Biomedical applications

Design and Development of Functional Biodegradable Polycarbo...

引用

第五届中美高分子科学与工程前沿论坛

作者： Chao Deng Fenghua Meng Ru Cheng Jian Zhang Zhiyuan Zhong Biomedical Polymers Laboratory and Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application College of Chemistry Chemical Engineering and Materials Science Soochow University

The ever growing biomedical technology such as regenerative medicine and controlled drug release intimately relies on the development of advanced functional biomaterials,among which aliphatic polycarbonates and polypeptides due to their excellent biocompatibility and biodegradability have received the most *** the past years,various types of functional polycarbonates and polypeptides have been

关键词： design and Development of functional Biodegradable Polycarbonates and Polypeptides for Emerging Biomedical applications

来源：评论

学校读者我要写书评

暂无评论

Iron-mediated AGET ATRP of Styrene and Methyl Methacrylate Using Ascorbic Acid Sodium Salt as Reducing Agent

引用

Chinese Journal of polymer Science 2014年第8期32卷 1010-1018页

作者： Jin-long Pan Zhen Li Li-fen Zhang 程振平朱秀林 Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application Department of Polymer Science and Engineering College of Chemistry Chemical Engineering and Materials Science Soochow University

Atom transfer radical polymerization of styrene （St） and methyl methacrylate （MMA） in bulk and in different solvents using activators generated by electron transfer （AGET ATRP） were investigated in the presence of a limited amount of air using FeC13-6H2O as the catalyst, ascorbic acid sodium salt （AsAc-Na） as the reducing agent, and a cheap and commercially available tetrabutylammonium bromide （TBABr） as the ligand. It was found that polymerization in THF resulted in shorter induction period than that in bulk and in toluene for AGET ATRP of St, while referring to AGET ATRP of MMA, polymerization in THF showed three advantages compared with that in bulk and toluene：1） shortening the induction period, 2） enhancing the polymerization rate and 3） having better controllability. The living features of the obtained polymers were verified by chain end analysis and chain-extension experiments.

关键词： Atom transfer radical polymerization （ATRP） AGET ATRP Iron catalyst Kinetics （polym.）.

来源：评论

学校读者我要写书评

暂无评论

A low-toxic and bioreducible polymeric nanocarrier for glutathione-mediated intracellular release of antineoplastic agent

A low-toxic and bioreducible polymeric nanocarrier for gluta...

引用

The 6th International Conference on Nanoscience & Technology, China 2015

作者： Jinlin He Fei Li Pengfei Ju Dongling Cao Mingzu Zhang Peihong Ni College of Chemistry Chemical Engineering and Materials ScienceSuzhou Key Laboratory of Macromolecular Design and Precision SynthesisJiangsu Key Laboratory of Advanced Functional Polymer Design and ApplicationSoochow University

As one of the main therapeutic methods toward cancers, chemotherapy can efficiently inhibit tumor growth in a large extent [1]. However, it is usually restricted with the severe cytotoxicity of antineoplastic agents against normal tissues and organs. To address this issue, various kinds of drug formulations have been fabricated to balance the minimization of undesirable adverse effects and the improvement of therapeutic efficacy [2,3]. Method: A stimuli-responsive amphiphilic triblock copolymer poly(ethylethylene phosphate)-blockpoly(disulfide)s-block-poly(ethylethylene phosphate)(PEEP-b-PDS-b-PEEP) is prepared via a combination of polycondensation and ring-opening polymerization, which serves as a low-toxic nanocarrier for the loading and triggered release of clinically used doxorubicin(DOX). Results: The spherical micelles are fabricated from the self-assembly of these amphiphilic triblock copolymers in aqueous solution. As a representative antineoplastic agent, DOX is efficiently encapsulated in thehydrophobic core of micelles. The DOX release is proceeded in a cytoplasmic glutathione-mediated way, which facilitates the triggered release inside the tumor tissues. In addition, the MTT tests indicate that these copolymers exhibit low cytotoxicity. Conclusions: The preliminary in vitro drug release and cytotoxicity assays reveal that this novel reduction-responsive polymeric nanocarrier shows great potential in cancer chemotherapy.

关键词： Cancer chemotherapy,polymeric nanocarrier,Biosafety,Biodegradability

来源：评论

学校读者我要写书评

暂无评论

Amplified Detection of Iron Ion Based on Plasmon Enhanced Fluorescence and Subsequently Fluorescence Quenching

引用

Nano-Micro Letters 2014年第4期6卷 327-334页

作者： Lin Zhou Han Zhang Yanping Luan Si Cheng Li-Juan Fan Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application College of Chemistry Chemical Engineering and Materials Science Soochow University

A facile and rapid approach for detecting low concentration of iron ion(Fe3+) with improved sensitivity was developed on the basis of plasmon enhanced fluorescence and subsequently amplified fluorescence ***1Ag4@Si O2 nanoparticles were synthesized and dispersed into fluorescein isothiocyanate(FITC) solution. The fluorescence of the FITC solution was improved due to plasmon enhanced fluorescence. However, efficient fluorescence quenching of the FITC/Au1Ag4@Si O2 solution was subsequently achieved when Fe3+, with a concentration ranging from17 n M to 3.4 l M, was added into the FITC/Au1Ag4@Si O2 solution, whereas almost no fluorescence quenching was observed for pure FITC solution under the same condition. FITC/Au1Ag4@Si O2 solution shows a better sensitivity for detecting low concentration of Fe3+compared to pure FITC solution. The quantized limit of detection toward Fe3+was improved from 4.6 l M for pure FITC solution to 20 n M for FITC/Au1Ag4@Si O2 solution.

关键词： Gold–silver alloy Plasmon enhanced fluorescence Fluorescence quenching Iron ion

来源：评论

学校读者我要写书评

暂无评论

Photo-induced Living Cationic Copolymerization of Isobutyl Vinyl Ether and Vinyl Ether with Carbazolyl Groups

引用

Chinese Journal of polymer Science 2014年第11期32卷 1564-1574页

作者： Ming Li 张丽芬 Mei-xia Tao 程振平 Xiu-lin Zhu Suzhou Key Laboratory of Macromolecular Design and Precision Synthesis Jiangsu Key Laboratory of Advanced Functional Polymer Design and ApplicationDepartment of Polymer Science and EngineeringCollege of ChemistryChemical Engineering and Materials ScienceSoochow University

In this work, a fluorescent monomer 2-（9-carbazolyl） ethyl vinyl ether（CEVE） was synthesized in our lab, and its photo-induced living cationic copolymerization behavior with isobutyl vinyl ether（IBVE） was investigated in detail using diphenyliodonium chloride（DPICl）/2,2-dimethoxy-2-phenylacetophenone（DMPA） and zinc bromide（Zn Br2） initiating system in dichloromethane solution at 5 °C, -5 °C, and -15 °C, respectively. The living nature of this copolymerization system was confirmed by adding fresh comonomer method after the copolymerization almost finished. In addition, the obtained fluorescent copolymer poly（IBVE-co-CEVE） has a low glass transition temperature（Tg）, below -10 °C.

关键词： Photopolymerization Kinetics（polym.） Copolymerization Cationic polymerization Living cationic polymerization.

来源：评论

学校读者我要写书评

暂无评论

Micelles, Microgels and Hydrogels Based on Polyphosphoesters for Anti-Cancer Drug Delivery

Micelles, Microgels and Hydrogels Based on Polyphosphoesters...

引用

The 5th Asian Symposium on Emulsion polymerization and functional polymeric Microspheres

作者： Peihong Ni Jian Hu Yan Xiao Jinlin He Mingzu Zhang College of Chemistry Chemical Engineering and Materials ScienceSuzhou Key Laboratroy of Macromolecular Design and Precision SynthesisJiangsu Key Laboratory of Advanced Functional Polymer Design and ApplicationSoochow University

Polyphosphoesters(PPEs) have been a class of promising materials for biomedical applications because of their excellent biodegradability and biocompatibility, controlled synthesis, diversified structures, and versatile functionalities.[1,2] They can be degraded into small molecular components(phosphate, alcohol, and diols) by hydrolytic or enzymatic cleavage of the phosphoester bonds under physiological conditions. In recent years, our group has been focused on the synthesis of PPEs and their applications in anti-cancer drug delivery.[3,4]

关键词： Polyphosphoester Microgel Hydrogel Drug delivery

来源：评论

学校读者我要写书评

暂无评论

Inverted Solar Cells: Lowering the Work Function of ITO by Covalent Surface Grafting of Aziridine: application in Inverted polymer Solar Cells (vol 1, 1570004, 2015)

引用

advanced MATERIALS INTERFACES 2015年第4期2卷

作者： Song, Yingxue Yan, Li Zhou, Yi Song, Bo Li, Yongfang Suzhou Key Laboratory of Macromolecular Design and Precision Synthesis Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 China

来源：评论

学校读者我要写书评

暂无评论

Characterization of single-handed,coiled,carbonaceous,tubular nanoribbons

引用

Chinese Chemical Letters 2014年第6期25卷 879-882页

作者： Dan Liu Yong-Min Guo Yi Li Bao-Zong Li Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application Department of Polymer Science and EngineeringCollege of ChemistryChemical Engineering and Materials ScienceSoochow University

Left-handed, coiled, 4,4＇-biphenylene bridged polybissilsesquioxane, tubular nanoribbons were prepared according to the published literature. After carbonization and removal of silica using HF aqueous solution, left-handed, coiled, carbonaceous, tubular nanoribbons were obtained. The left- handed, coiled, carbonaceous, tubular nanoribbons were characterized using field-emission scanning electron microscopy, transmission electron microscopy, powder X-ray diffraction, Raman spectropho- tometer, diffuse reflectance circular dichroism （DRCD）, and N2 adsorptions. Micropores were formed due to the removal of silica. The nitrogen BET surface area is 1727 m2/g. A broad, positive DRCD signal, identified at 400-800 rim, indicates the carbonaceous, tubular nanoribbons exhibit optical activity. The helical pitch is proposed to play an important role in the position of the DRCD signal.

关键词： Nanoparticles Carbon/silica Sol-gel preparation Structural

来源：评论

学校读者我要写书评

暂无评论

Preparation of single-handed helical phenolic resin nanoflbers using a supramolecular templating method

引用

Chinese Chemical Letters 2014年第10期25卷 1363-1366页

作者： Li-Qing Ma Hao Chen Yong-Min Guo Bao-Zong Li Yi Li Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application Department of Polymer Science and EngineeringCollege of ChemistryChemical Engineering and Materials ScienceSoochow University

Single-handed helical phenolic resin nanofibers were synthesized through a supramolecular templating approach using the supramolecular self-assemblies of a pair of chiral low-molecular-weight amphiphiles as the templates and 2,4-dihydroxybenzoic acid and formaldehyde as the *** phenolic resin nanofibers were characterized using field-emission scanning electron microscopy,transmission electron microscopy and diffused reflection circular *** results indicated that the chirality of the supramolecular self-assemblies was successfully transferred to the phenolic resin *** left- and right-handed helical phenolic resin nanofibers exhibited opposite optical activity.

关键词： Supramolecular template Chirality Phenolic resins Nanofibers

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：