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Control Engineering and robotics (ISCER), International Symposium on

作者： Xian Wu Lei Lu Chengyun Yang Wenjie Li Yinan Wang Haoran Zhao Lei Zhang Jiangsu Provincial Key Laboratory of Advanced Robotics&Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow University Suzhou China

Precise and rapid shaft hole assembly is important for improving equipment performance and assembly efficiency. As the variety of parts and shapes, the accuracy and efficiency of manual assembly are limited. In this paper, a shaft hole assembly method by using image recognition algorithm and robot is proposed. In the image recognition process, a shape recognition method based on 2D point cloud matching is presented, and combined with robot to realize grasping and assembly movement. In order to improve the recognition accuracy and reduce the real-time computational complexity, the method with binarization, Gauss filtering and shape recognition are provided to process the image obtained from camera. The experiment results show that the proposed image recognition could effectively identify part shape and complete the assembly process accurately, i.e., the method could effectively improve the efficiency and accuracy of shaft hole assembly.

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Modulating Strengthening Ability of Layer-Grained Fcc Metals with Distinct Stacking Fault Energy, Molecular Dynamics Simulation

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SSRN 2023年

作者： Jing, Peng Wang, Yu Zhou, Yuankai School of Mechanical Engineering Jiangsu University of Science and Technology Zhenjiang212003 China Jiangsu Provincial Key Laboratory of Advanced Manufacturing for Marine Mechanical Equipment Jiangsu University of Science and Technology Zhenjiang212003 China

The limited ductility of nanocrystalline metals severely hinders their practical applications due to the absence of strain hardening. In this study, we observe strain hardening in layer-grained models through molecular dynamics simulations. Our quantitative analysis demonstrates that grain boundary deformation induces strain hardening, while dislocation activities lead to strain softening in the simulation model. This finding is fundamentally different from previous assumptions that dislocation activities cause strain hardening, and grain boundary deformation leads to strain softening. The competition between grain boundary deformation and dislocation activities determines the strain hardening behaviors in nanocrystalline metals. By modifying the stacking fault energy and tailoring lamellar grains, it is possible to increase the proportion of grain boundary deformation and achieve ductility in strong nanocrystalline metals. Such materials, which exhibit high strength and good ductility, hold great potential for a wide range of industrial and engineering applications. © 2023, The Authors. All rights reserved.

关键词： Molecular dynamics

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Design of A Bionic Spudcan and Analysis of Penetration and Extraction Performances for Jack-up Platform

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China Ocean Engineering 2020年第1期34卷 80-88页

作者： GUO Sheng ZHUANG Hong TANG Wen-xian WU Wen-le LIU Qin WANG Yue-yang School of Mechanical Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China Jiangsu Provincial Key Laboratory of Advanced Manufacturing for Marine Mechanical Equipment Jiangsu University of Science and TechnologyZhenjiang 212003China

The mechanisms of soil structure interaction have drawn much attention in the past years in the installation and operation of jack-up platform. A bionic spudcan produced by biomimetic of egg and snail shell is proposed, and the performance of the penetration and extraction are analyzed by numerical method. The geometric contour of egg and snail shell is measured, and its mathematical model is established respectively. According to the structure of existing spudcan of jack-up platform, three kinds of typical biomimetic spudcan are designed. Furthermore, numerical analysis models of biomimetic spudcan are established respectively to study the soil structure interaction mechanism in the process of penetration and extraction, and contrastive analysis of resistance characteristics are carried out. To conclude, the results show that the biomimetic spudcan facilitates the platform installation, and it is also beneficial to the improvement of the bearing capacity of spudcan.

关键词： jack-up platform egg shell snail shell bionic design spudcan soil structure interaction

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Microstructure Evolution and Growth Kinetics of Cu6sn5 Intermetallic Compound at Liquid-Solid Interfaces in Cu/Sn/Cu Interconnects Under Ultrasonic Waves

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SSRN 2024年

作者： Niu, Hongwei Bian, Hong Wang, Jian Song, Xiaoguo Zhao, Hongyun School of Materials Engineering Jiangsu University of Technology Changzhou213001 China State Key Laboratory of Advanced Welding and Joining Harbin Institute of Technology Harbin150001 China Shandong Provincial Key Laboratory of Special Welding Technology Harbin Institute of Technology at Weihai Weihai264209 China

The microstructure evolution and growth kinetics of Cu6Sn5 intermetallic compound (IMC) in a Cu/Sn/Cu interconnection structure during the ultrasonic-assisted transient liquid phase (TLP) soldering process were investigated. Being different from the symmetrical growth during isothermal aging without ultrasonic waves (USW), highly asymmetrical growth of Cu6Sn5 at the upper and lower Sn/Cu interfaces was observed with USW. Cu6Sn5 grains exhibited scallop-type morphology, and were discrete at the upper interface;while that at the lower Sn/Cu interface exhibited column-type morphology, and were conterminous at the lower interface. USW caused the mass migration of Cu atoms from the upper Cu surface toward the lower interface, resulting in sufficient Cu atomic ﬂux for the fast formation of Cu6Sn5 at the lower interface, and many cavitation pits on the upper Cu surface. A growth model was established to explain the growth kinetics of the Cu6Sn5 IMC, indicating a reaction-controlled growth mechanism. © 2024, The Authors. All rights reserved.

关键词： Growth kinetics

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Revisiting astrocytic calcium signaling in the brain

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Fundamental Research 2024年第6期4卷 1365-1374页

作者： Ying Bai Zhongqiu Zhou Bing Han Xianyuan Xiang Wenhui Huang Honghong Yao Department of Pharmacology Jiangsu Provincial Key Laboratory of Critical Care MedicineSchool of MedicineSoutheast UniversityNanjing 210009China Shenzhen Institute of Advanced Technology Chinese Academy of SciencesShenzhen 518055China Molecular Physiology CIPMMUniversity of SaarlandHomburg 66421Germany Co-innovation Center of Neuroregeneration Nantong UniversityNantong 226001China Institute of Life Sciences Key Laboratory of Developmental Genes and Human DiseaseSoutheast UniversityNanjing 210096China Center for Global Health School of Public HealthNanjig Medical UniversityNanjing 211166China

Astrocytes,characterized by complex spongiform morphology,participate in various physiological processes,and abnormal changes in their calcium(Ca^(2+))signaling are implicated in central nervous system ***,medications targeting the control of Ca^(2+)have fallen short of the anticipated therapeutic outcomes in clinical *** underscores the fact that our comprehension of this intricate regulation of calcium ions remains considerably *** recent years,with the advancement of Ca^(2+)labeling,imaging,and analysis techniques,Ca^(2+)signals have been found to exhibit high specificity at different spatial locations within the intricate structure of *** has ushered the study of Ca^(2+)signaling in astrocytes into a new phase,leading to several groundbreaking research *** this,the comprehensive understanding of astrocytic Ca^(2+)signaling and their implications remains challenging area for future research.

关键词： Astrocyte Ca^(2+)signaling Central nervous system Synapse Ion channel

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Micro-LED for short distance optical links with low power consumption

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Optics Letters 2025年第10期50卷 3453-3456页

作者： Xu, Feifan Zhao, Rui Tao, Tao Zhi, Ting Tian, Pengfei Deng, Gaoqiang Zhuang, Zhe Xie, Zili Zhang, Yuantao Zhang, Rong Liu, Bin The Jiangsu Provincial Key Laboratory of Advanced Photonic and Electronic Materials School of Electronic Science and Engineering Nanjing University Nanjing210093 China The College of Electronic and Optical Engineering Nanjing University of Posts and Telecommunications Nanjing210093 China The School of Information Science and Technology Fudan University Shanghai200433 China The School of Integrated Circuits Nanjing University Suzhou215163 China The College of Electronic Science and Engineering Jilin University Changchun130012 China

Optical interconnects have been recognized as a transformative approach for data centers. This paper presents an investigation of Micro-LED-based signal emitters for high-speed optical interconnection systems. By utilizing optimized quantum well and current injection structures, high-speed Micro-LEDs were fabricated, and their carrier injection efficiency, modulation bandwidth, and signal quality were thoroughly characterized. A high bandwidth exceeding 1 GHz was achieved in a single Micro-LED at an injection current of 2 mA, and the maximum exceeds 1.6 GHz. Notably, a single Micro-LED supported high signal transmission rates up to 3.07 Gbps using the NRZ modulation format. Additionally, the power consumption was measured to be only 7.34 pJ/bit for 2.125 Gbps signal transmission, with a bit error rate (BER) of 2.4E-3. These results reveal the promising potential of compact Micro-LEDs for integrated optical links, with significant room remaining for improvement, particularly in power consumption reduction. © 2025 Optica Publishing Group. All rights, including for text and data mining (TDM), Artificial Intelligence (AI) training, and similar technologies, are reserved.

关键词： Bit error rate Optical interconnects Optical signals Optical systems Signal processing Signal transmission

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Dock4 is required for the maintenance of cochlear hair cells and hearing function

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自然科学基础研究（英文） 2023年第4期3卷 557-569页

作者： Guodong Hong Xiaolong Fu Jieyu Qi Buwei Shao Xuan Han Yuan Fang Shuang Liu Cheng Cheng Chengwen Zhu Junyan Gao Xia Gao Jie Chen Ming Xia Wei Xiong Renjie Chai State Key Laboratory of Digital Medical Engineering Department of Otolaryngology Head and Neck SurgeryZhongda HospitalSchool of Life Sciences and TechnologyAdvanced Institute for Life and HealthJiangsu Province High-Tech Key Laboratory for Bio-Medical ResearchSoutheast UniversityNanjing 210096China School of Life Sciences IDG/McGovem Institute for Brain ResearchTsinghua UniversityBeijing 100083China Department of Otolaryngology Head and Neck Surgery Jiangsu Provincial Key Medical Discipline(Laboratory)Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjing 210008China Research Institute of Otolaryngology Nanjing 210008China Department of Otolaryngology Head and Neck Surgery Jiangsu Provincial Key Medical Discipline(Laboratory)Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjing 210008China Jiangsu Rehabilitation Research Center for Hearing and Speech Impairment NanjingJiangsu 210004China Department of Otolaryngology Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityShandong 250000China Medical Science and Technology Innovation Center Shandong First Medical University & Shandong Academy of Medical SciencesShandong 250022China State Key Laboratory of Digital Medical Engineering Department of Otolaryngology Head and Neck SurgeryZhongda HospitalSchool of Life Sciences and TechnologyAdvanced Institute for Life and HealthJiangsu Province High-Tech Key Laboratory for Bio-Medical ResearchSoutheast UniversityNanjing 210096China Co-Innovation Center of Neuroregeneration Nantong UniversityNantong 226001China Institute for Stem Cell and Regeneration Chinese Academy of ScienceBeijing 100101China Beijing Key Laboratory of Neural Regeneration and Repair Capital Medical UniversityBeijing 100069China Department of Otolaryngology Head and Neck Surgery Sichuan Provincial People's HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610072China

Auditory hair cells(HCs)are the mechanosensory receptors of the cochlea,and HC loss or malfunction can re-sult from genetic ***4,a member of the Dock180-related protein superfamily,is a guanine nucleotide exchange factor for Rac1,and previous reports have shown that Dock4 mutations are associated with autism spec-trum disorder,myelodysplastic syndromes,and ***,we found that Dock4 is highly expressed in the cochlear HCs of ***,the role of Dock4 in the inner ear has not yet been *** advantage of the piggyBac transposon system,Dock4 knockdown(KD)mice were established to explore the role of Dock4 in the *** to wild-type controls,Dock4 KD mice showed significant hearing impairment from postnatal day ***4 KD mice showed hair bundle deficits and increased oxidative stress,which even-tually led to HC apoptosis,late-onset HC loss,and progressive hearing ***,molecular mechanism studies showed that Rac1/β-catenin signaling was significantly downregulated in Dock4 KD cochleae and that this was the cause for the disorganized stereocilia and increased oxidative stress in ***,our work demon-strates that the Dock4/Rac1/β-catenin signaling pathway plays a critical role in the maintenance of auditory HCs and hearing function.

关键词： Hair cell Stereocilia Oxidative stress Apoptosis Hearing loss Dock4

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Safety Protection Method of Rehabilitation robot Based on fNIRS and RGB-D Information Fusion

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Journal of Shanghai Jiaotong university(Science) 2022年第1期27卷 45-54页

作者： LI Dong FAN Yulin LU Na CHEN Guodong WANG Zheng CHI Wenzheng School of Mechanical and Electrical Engineering/Jiangsu Provincial Key Laboratory of Advanced Robotics/Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow UniversitySuzhou 215123JiangsuChina Department of Gerontology Shanghai Jiao Tong University Affiliated Sixth People’s HospitalShanghai 200233China Department of Instrument Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China

In order to improve the safety protection performance of the rehabilitation robot,an active safety protection method is proposed in the rehabilitation *** oxyhemoglobin concentration information and RGB-D information are combined in this method,which aims to realize the comprehensive monitoring of the invasion target,the patient’s brain function movement state,and the joint angle in the rehabilitation *** main focus is to study the fusion method of the oxyhemoglobin concentration information and RGB-D information in the rehabilitation *** analysis of brain functional connectivity coefficient was used to distinguish the basic motion *** human skeleton recognition algorithm was used to realize the angle monitoring of the upper limb joint combined with the depth *** with speed and separation monitoring,the protection method of multi-information fusion is safer and more comprehensive for stroke *** building the active safety protection platform of the upper limb rehabilitation robot,the performance of the system in different safety states is tested,and the safety protection performance of the method in the upper limb rehabilitation scene is verified.

关键词： upper limb rehabilitation robot safety protection functional near-infrared spectroscopy(fNIRS) multi-information fusion

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Dynamic Obstacle Avoidance for Application of Human-robot Cooperative Dispensing Medicines

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Journal of Shanghai Jiaotong university(Science) 2022年第1期27卷 24-35页

作者： WANG Zheng XU Hui LU Na TAO Wei CHEN Guodong CHI Wenzheng SUN Lining Department of Gerontology Shanghai Jiao Tong University Affiliated Sixth People’s HospitalShanghai 200233China School of Mechanical and Electrical Engineering/Jiangsu Provincial Key Laboratory of Advanced Robotics/Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow UniversitySuzhou 215123JiangsuChina Department of Instrument Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China

For safety reasons,in the automated dispensing medicines process,robots and humans cooperate to accomplish the task of drug sorting and *** this dynamic unstructured environment,such as a humanrobot collaboration scenario,the safety of human,robot,and equipment in the environment is *** this work,a practical and effective robot motion planning method is proposed for dynamic unstructured *** figure out the problems of blind zones of single depth sensor and dynamic obstacle avoidance,we first propose a method for establishing offline mapping and online fusion of multi-sensor depth images and 3D grids of the robot workspace,which is used to determine the occupation states of the 3D grids occluded by robots and obstacles and to conduct real-time estimation of the minimum distance between the robot and ***,based on the reactive control method,the attractive and repulsive forces are calculated and transformed into robot joint velocities to avoid obstacles in real ***,the robot’s dynamic obstacle avoidance ability is evaluated on an experimental platform with a UR5 robot and two KinectV2 RGB-D sensors,and the effectiveness of the proposed method is verified.

关键词： automated dispensing medicines dynamic unstructured environment human-robot collaboration dynamic obstacle avoidance multi-sensor depth images 3D grids reactive control method

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Data-consistent Unsupervised Diffusion Model for Metal Artifact Reduction

Data-consistent Unsupervised Diffusion Model for Metal Artif...

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2023 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2023

作者： Tong, Zhan Wu, Zhan Yang, Yang Mao, Weilong Wang, Shijie Li, Yinsheng Chen, Yang Southeast University Laboratory of Image Science and Technology Nanjing210096 China Southeast University Ministry of Education Key Laboratory of Computer Network and Information Integration Nanjing210096 China Chinese Academy of Sciences Research Center for Medical Artificial Intelligence Shenzhen Institutes of Advanced Technology Shenzhen518055 China School of Computer Science and Engineering Key Lab. of New Generation Artificial Intelligence Technology and Its Interdisciplinary Applications Jiangsu Provincial Joint International Research Laboratory of Medical Information Processing The Laboratory of Image Science and Technology Nanjing210096 China

ISBN: (纸本)9798350337488

Computed Tomography (CT) is an imaging technique widely used in clinical diagnosis. However, high-attenuation metallic implants result in the obstruction of low-energy Xrays and further lead to metal artifacts in the reconstructed CT images. Deep supervised model-based metal artifact reduction(MAR) approaches are limited in clinical applications due to the difficulty in obtaining paired artifact-affected and artifactfree data. Furthermore, these model-based methods lack the consideration of data consistency in the sinogram-domain to perform exact metal trace inpainting. To address these challenges, we propose a Data-consistent unsupErVised diffusiOn model for meTal artifact rEDuction, called DEVOTED-Net. First, DEVOTED-Net leverages prior knowledge to guide the conditional diffusion model for fine-grained metal trace inpainting. Second, an unsupervised MAR framework is designed in the reverse process for the unknown metal traces restoration in the sinogram domain. Third, to further enhance the sinogram-domain data consistency, physics-based consistency constraint loss including conjugateray consistency loss and accumulation-ray consistency loss is designed. Extensive experiments are carried out to verify the performance of our algorithm on the publicly available dataset and clinical experimental dataset. This efficient, accurate, and reliable MAR approach holds great potential in clinics. © 2023 IEEE.

关键词： computed tomography deep unsupervised learning denoising diffusion probabilistic model Metal artifact reduction physics-based consistency constraint

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