Performance of an adaptive controller for automatic regulation of level of induced paralysis during surgery, using vecuronium bromide, is presented. In addition to adapting to variations in patient dynamic response pa...
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Performance of an adaptive controller for automatic regulation of level of induced paralysis during surgery, using vecuronium bromide, is presented. In addition to adapting to variations in patient dynamic response parameters, the controller accommodates any variation in the pure time delays of the response. The performance results are obtained from a computer simulation of the nonlinear patients pharmacokinetic and pharmacodynamic response to the drug.
FET based ion sensors appear promising as monitoring and diagnostic aids in clinical medicine. The principles underlying these miniaturized probes are outlined. The fifteen year development period, since their origina...
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FET based ion sensors appear promising as monitoring and diagnostic aids in clinical medicine. The principles underlying these miniaturized probes are outlined. The fifteen year development period, since their original description, is related to problems with reliability, biological compatibility, and incorporation of reference electrodes. Possible solutions to these problems are outlined. Some results of in vivo experimental and clinical measurements are reviewed which demonstrate their promise.
This report discusses those FET-based devices which, by virtue of their potential for miniaturization, low cost production, and operational stability, may be useful for monitoring and diagnostic procedures. Other meth...
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This report discusses those FET-based devices which, by virtue of their potential for miniaturization, low cost production, and operational stability, may be useful for monitoring and diagnostic procedures. Other methods allow detection of specific metabolic substrates, for example, fiberoptic-based chemical sensors and nuclear magnetic resonance techniques. Those methods are outside the scope of this discussion, but have been covered in recent books and reviews. The principles underlying the FET chemical sensor, and the design embodiments for medical applications are described. The current status and future requirements to bring these devices to the clinical medical instrumentation arena are assessed.
This review outlines the information processing tasks which involve the interaction between the patient and the provider of health care services. These areas include the clinical laboratory, automated multiphasic heal...
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This review outlines the information processing tasks which involve the interaction between the patient and the provider of health care services. These areas include the clinical laboratory, automated multiphasic health testing, medical records, patient monitoring, diagnostic support systems, and medical imaging. Health care professionals, including clinical engineers, must recognize the potential, understand basic principles, and utilize computers effectively during the next decade's rapid advances.
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