This paper proposes a Complex-Valued Neural Network (CVNN) for glucose sensing in milli-meter wave (mmWave). Based on the propagation characteristics of millimeter wave in glucose medium, we obtain the S21 parameter o...
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Tissue engineered skeletal muscle has potential to be used for the therapy of muscular dysfunction. In order to engineer skeletal muscle that better resemble the structured architecture in vivo, we cultured myoblasts ...
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Tissue engineered skeletal muscle has potential to be used for the therapy of muscular dysfunction. In order to engineer skeletal muscle that better resemble the structured architecture in vivo, we cultured myoblasts on topographically micropatterned elastic polymer films with 10-μm wide microgrooves. The organization and differentiation of myoblasts on nonpatterned and micropatterned PDMS films were characterized. In comparison to the myoblasts on nonpatterned PDMS films, myoblasts on micropatterned PDMS films aligned themselves along the direction of the microgrooves. The myoblasts on micropatterned films formed long and unbranched myotubes that had uniform diameter and aligned in the microgroove direction, suggesting that microgrooves promote end-to end fusion of myoblasts;in contrast, myotubes formed on nonpatterned surface were short and less uniform in diameter, and oriented in various directions. This study demonstrates a new approach to engineer muscular tissues on flexible substrate, and highlights the importance of topographical cues for creating more physiologically relevant environments to study myogenesis and engineer skeletal muscle.
In this study, an attempt was made to describe the age-related changes in pentosidine levels in isolated bone collagen and intact bone, and to determine the effect of increased pentosidine cross-link density on the du...
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ISBN:
(纸本)0791816117
In this study, an attempt was made to describe the age-related changes in pentosidine levels in isolated bone collagen and intact bone, and to determine the effect of increased pentosidine cross-link density on the ductility of both bone collagen and intact bone. Fifty-six cortical bone specimens were machined and assigned into four groups: intact, cross-link enhanced, demineralized, and demineralized cross-link enhanced. The specimens were then tested to failure in uniaxial tension. The results indicate that pentosidine cross-link density increases with age and that this leads to a decrease in ductility in both bone and isolated collagen.
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