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1st IEEE International Conference on Medical Artificial Intelligence, MedAI 2023

作者： Xu, Xin Lu, Wenjing Lei, Jiahao Qiu, Peng Shen, Hong-Bin Yang, Yang Shanghai Jiao Tong University Key Lab. of Shanghai Education Commission for Intelligent Interaction and Cognitive Engineering Department of Computer Science and Engineering Shanghai200240 China Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Department of Vascular Surgery China Shanghai Jiao Tong University Institute of Image Processing and Pattern Recognition Key Laboratory of System Control and Information Processing Ministry of Education of China Shanghai200240 China

ISBN: (纸本)9798350358780

Interactive medical image segmentation methods have become increasingly popular in recent years. These methods combine manual labeling and automatic segmentation, reducing the workload of annotation while maintaining high accuracy. However, most current interactive segmentation frameworks are limited to 2D image data, and are not suitable for 3D image data due to the large size and high complexity of 3D data, as well as the challenges posed by information asymmetry and sparse annotation. In this paper, we propose SliceProp, an interactive segmentation framework that implements slice-wise label Bidirectional Propagation (LBP) for 3D medical image segmentation. SliceProp extends the interactive 2D image segmentation algorithm to 3D image segmentation, and can handle 3D data with large size and high complexity. Moreover, equipped with a Backtracking Feedback Check (BFC) module, SliceProp effectively addresses the issues of information asymmetry and spatial sparse annotation in 3D medical image segmentation. Additionally, we adopt an uncertainty-based criterion to pri-oritize the slices to be refined interactively, which enhances the efficiency of the interaction process by enabling the model to focus on the regions with the most unreliable predictions. SliceProp is evaluated on two datasets and achieves promising results compared to state-of-the-art methods. © 2023 IEEE.

关键词： Medical imaging

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Isoform Function Prediction Based on Heterogeneous Graph Attention Networks

Isoform Function Prediction Based on Heterogeneous Graph Att...

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2023 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2023

作者： Guo, Kuo Li, Yifan Chen, Hao Shen, Hong-Bin Yang, Yang Shanghai Jiao Tong University Key Lab. of Shanghai Education Commission for Intelligent Interaction and Cognitive Engineering Department of Computer Science and Engineering Shanghai200240 China Shanghai Jiao Tong University Key Laboratory of System Control and Information Processing Ministry of Education of China Institute of Image Processing and Pattern Recognition Shanghai200240 China Carnegie Mellon University School of Computer Science Computational Biology Department PittsburghPA15213 United States

ISBN: (纸本)9798350337488

Isoforms refer to different mRNA molecules transcribed from the same gene, which can be translated into proteins with varying structures and functions. Predicting the functions of isoforms is an essential topic in bioinformatics as it can provide valuable insights into the intricate mechanisms of gene regulation and biological processes. Conventionally, gene function labels are standardized in Gene Ontology (GO) terms. However, traditional methods for predicting isoform function are largely limited by the absence of isoform-specific labels, sparse annotations, and the vast number of GO terms. To address these issues, we propose HANIso, a deep learning-based method for isoform function prediction. HANIso leverages a pretrained protein language model to extract features from protein sequences. It also integrates heterogeneous information, such as isoform sequence features, GO annotations, and isoform interaction data, using a Heterogeneous Graph Attention Network (HAN). This allows the model to learn the importance of different sources of information and their semantic relationships through the attention mechanism. Our method can predict function labels at both the gene level and isoform level. We conduct experiments on two species datasets, and the results demonstrate that our method outperforms existing methods on both AUROC and AUPRC. HANIso has the potential to overcome the limitations of traditional methods and provide a more accurate and comprehensive understanding of isoform function. © 2023 IEEE.

关键词： alternative splicing gene ontology heterogeneous graph attention network isoform function prediction protein language model

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A 4-Channel Ultrafast Wavelength-Swept REC-DFB Laser Array for Fiber Bragg Grating Interrogation

A 4-Channel Ultrafast Wavelength-Swept REC-DFB Laser Array f...

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2023 Asia Communications and Photonics Conference/2023 International Photonics and Optoelectronics Meetings, ACP/POEM 2023

作者： Meng, Lingxin Dai, Pan Ban, Qilu Xu, Kaichuan Wang, Jiacheng Li, Zhen Wang, Feng Zeng, Jie Li, Shaobo Ma, Xiang Chen, Xiangfei Res. Center of Precision Photonics Integration and System Application of the Ministry of Education College of Engineering and Applied Sciences Nanjing University Key Lab. of Intelligent Optical Sensing and Manipulation of the Ministry of Education Engineering National Laboratory of Solid State Microstructures Nanjing210023 China Nanjing University of Aeronautics and Astronautics State Key Laboratory of Mechanics and Control for Aerospace Structures Nanjing210016 China The 54th Research Institute of China Electronics Technology Group Corporation Optical Communication Research and Development Center Shijiazhuang050081 China

ISBN: (纸本)9798350312614

We present a four-channel ultrafast wavelength-swept distributed feedback (DFB) semiconductor laser array based on the reconstruction-equivalent-chirp (REC) technique using instantaneous injection current modulation. With the aid of our designed laser driving circuit system consists of the microcontroller unit (MCU), field-programmable gate array (FPGA) and negative metal-oxide-semiconductor field effect transistors (n-MOSFETs), the precise pulse driving current for the 4-channel wavelength-swept REC-DFB laser array can be generated and a fast tuning of 16.424 nm within 10 μs is achieved. To further investigate the tuning performance of the proposed wavelength-swept laser source, we then applied it to the fiber Bragg grating (FBG) interrogation system and four FBG temperature sensor arrays were successfully demodulated. The development of high-efficient optical sensing systems heavily relies on the significance of the ultrafast wavelength-swept laser source, which has the potential to greatly enhance FBG interrogator performance in the future. © 2023 IEEE.

关键词： DFB laser array fast wavelength-swept fiber Bragg grating interrogation REC technique

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Mesenchymal stem cells loaded on 3D-printed gradient poly(e-caprolactone)/methacrylated alginate composite scaffolds for cartilage tissue engineering

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Regenerative Biomaterials 2021年第3期8卷 70-83页

作者： Yanyan Cao Peng Cheng Shengbo Sang Chuan Xiang Yang An Xiaochun Wei Zhizhong Shen Yixia Zhang Pengcui Li Key Lab of Advanced Transducers and Intelligent Control System of the Ministry of Education MicroNano System Research CenterCollege of Information and ComputerTaiyuan University of TechnologyTaiyuan 030024China College of Information Science and Engineering Hebei North UniversityZhangjiakou 075000China Shanxi Key Laboratory of Bone and Soft Tissue Injury Repair Department of OrthopedicsThe Second Hospital of Shanxi Medical UniversityTaiyuan 030001China Department of Plastic Surgery Peking University Third HospitalBeijing 100191China Department of Biomedical Engineering College of Biomedical EngineeringTaiyuan University of TechnologyTaiyuan 030024China

Cartilage has limited self-repair ability due to its avascular,alymphatic and aneural *** combination of three-dimensional(3D)printing and tissue engineering provides an up-and-coming approach to address this ***,we designed and fabricated a tri-layered(superficial layer(SL),middle layer(ML)and deep layer(DL))stratified scaffold,inspired by the architecture of collagen fibers in native cartilage *** scaffold was composed of 3D printed depth-dependent gradient poly(e-caprolactone)(PCL)impregnated with methacrylated alginate(ALMA),and its morphological analysis and mechanical properties were *** prove the feasibility of the composite scaffolds for cartilage regeneration,the viability,proliferation,collagen deposition and chondrogenic differentiation of embedded rat bone marrow mesenchymal stem cells(BMSCs)in the scaffolds were assessed by Live/dead assay,CCK-8,DNA content,cell morphology,immunofluorescence and real-time reverse transcription polymerase chain ***-loaded gradient PCL/ALMA scaffolds showed excellent cell survival,cell proliferation,cell morphology,collagen II deposition and hopeful chondrogenic differentiation compared with three individual-layer ***,our study demonstrates the potential use of the gradient PCL/ALMA construct for enhanced cartilage tissue engineering.

关键词： three-dimensional printing cartilage tissue engineering PCL methacrylated alginate bone marrow mesenchymal stem cells

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Compound Fault Diagnosis of Planetary Gearbox Using Capsule Network with Multi-Scale Convolutional Neural Network

Compound Fault Diagnosis of Planetary Gearbox Using Capsule ...

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Prognostics and system Health Management Conference (PHM)

作者： Guoyan Li Jingbin Zhang Guoliang Lu School of Mechanical and Electrical Engineering University of Electronic Science and Technology of China Chengdu China Key Laboratory of Advance Transducers and Intelligent Control System Ministry of Education Taiyuan University of Technology Taiyuan China Key Laboratory of High-efficiency and Clean Mechanical Manufacture of MOE National Demonstration Center for Experimental Mechanical Engineering Education School of Mechanical Engineering Shandong University Jinan China

ISBN: (数字)9798350360585

ISBN: (纸本)9798350360592

Capsule network is an innovative deep learning-based model that uses neuron vectors as inputs and outputs of the network. It can achieve independent output of multiple classification labels, and solve the problem of decoupling recognition of compound fault components in planetary gearboxes. However, the single-scale feature extraction cannot fully explore multi-scale feature information in compound fault signals. This study proposes a capsule network combined with multi-scale convolutional feature fusion to diagnose the compound fault of planetary gearbox. The multi-scale features are extracted from STFT images of vibration signals using convolutional layers with different kernel sizes; secondly, a capsule network is designed to classify and identify the fault components by using the dynamic routing algorithm. The experiments are conducted to assess the performance of the proposed method, and the results indicates that it can effectively decoupling identify the compound faults with strong anti-interference and stability.

关键词： Fault diagnosis Vibrations Convolution Heuristic algorithms Feature extraction Stability analysis Vectors

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Black Phosphorus-Organic Framework-Derived Pei/Peg Nanohybrid Prepared by a One-Pot Method for a Wide Detection Range Co2 Gas Sensor

SSRN

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SSRN 2022年

作者： Liu, Lulu Sang, Shengbo Han, Dan Liu, Zhihua Han, Xiaomei Li, Donghui Chen, Yi Liu, Dongming Liu, Xiaoru Zhuo, Kai Cheng, Yongqiang Yang, Kun Shanxi Key Laboratory of Micro Nano Sensors & Artificial Intelligence Perception College of Information and Computer Taiyuan University of Technology Taiyuan030024 China Key Lab of Advanced Transducers and Intelligent Control System of the Ministry of Education Taiyuan University of Technology Taiyuan030024 China Key Laboratory of Interface Science and Engineering in Advanced Materials Taiyuan University of Technology Ministry of Education Taiyuan030024 China

In this paper, we report a hybrid PEI/PEG-BP sensor (composite material of black phosphorus-organic framework-derived PEI/PEG nanohybrid) prepared by a one-pot method, in which the existence of PEI/PEG onto BP was confirmed by SEM, EDS, XPS and UPS. The gas sensing properties of the PEI/PEG-BP sensor, including the sensor response, response/recovery times, repeatability, selectivity, and effects of humidity on the sensor, were studied by exposure to several CO 2 gas concentrations ranging from 200 ppm to 300,000 ppm at room temperature (25 ℃). The results show that the PEI/PEG-BP sensor had an extremely wide detection range, with lower and upper detection limits of 200 ppm and 160,000 ppm, respectively. The response of the PEI/PEG-BP sensor to 200 ppm, and 160,000 ppm CO 2 gas at room temperature ( RT ) was 4.48%, and 254.02%, respectively, showing fast response/recovery time, excellent repeatability and high selectivity. The gas-sensing properties of the PEI/PEG-BP sensor are better than BP, PEI, PEG, PEI-BP and PEG-BP sensors. The superior properties of the PEI/PEG-BP sensor can be attributed to the BP framework, porous structure, electron doping, and surface reactive groups such as -NH 2 and -OH. The PEI/PEG-BP sensor, with its excellent gas-sensing performance will help us to further explore the changes of CO 2 concentration in microbial growth systems, natural environments, industrial production and so on. © 2022, The Authors. All rights reserved.

关键词： Carbon dioxide

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Rapid Response and Recovery Performance of NO2 Gas Sensor Based on Gan Hexagonal Pits at Room Temperature

SSRN

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SSRN 2022年

作者： Han, Xiaomei Han, Dan Liu, Xiaoru Chen, Yi Liu, Lulu Liu, Zhihua Li, Donghui Sang, Shengbo Shanxi Key Laboratory of Micro Nano Sensors & Artificial Intelligence Perception College of Information and Computer Taiyuan University of Technology Taiyuan030024 China Key Lab of Advanced Transducers and Intelligent Control System The Ministry of Education Taiyuan University of Technology Taiyuan030024 China Key Laboratory of Interface Science and Engineering in Advanced Materials Taiyuan University of Technology Ministry of Education Taiyuan030024 China

Although fantastic milestones of Gallium nitride (GaN)-based materials in optoelectronic devices had been reached, the focus on the optimization of their geometrical structure for gas-sensing applications was relatively scarce. In this work, we demonstrated NO2 gas sensor based on p-type GaN hexagonal pits (GaN-HP) with high surface-to-volume ratio by wet etching method. The fabricated NO2 gas sensor had high sensitivity, high selectivity, fast response/recovery times. The response of p-type GaN-HP with etching time for 10 min to 2 ppm NO2 gas was 6.2%, which also have quick response and recovery time at room temperature. UV light drastically enhanced the response of p-type GaN-HP sensor by 1.3 times to 100 ppm NO2 . The gas sensing mechanism of p-type GaN-HP gas sensor was explored, which provided a theoretical and experimental basis for further research and development of high-performance gas sensors based on GaN material. © 2022, The Authors. All rights reserved.

关键词： Gallium nitride

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Brillouin Frequency Shift Extraction by Bidirectional Integration of Brillouin Gain Spectrum

SSRN

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SSRN 2023年

作者： Liu, Shuangshuang Zhang, Jianzhong Ma, Zhe Liang, Zefeng Han, Jinfeng Xu, Jinglang Zhang, Mingjiang Key Laboratory of Advanced Transducers and Intelligent Control System Ministry of Education and Shanxi Province Taiyuan University of Technology Taiyuan030024 China College of Electronic Information and Optical Engineering Taiyuan University ofTechnology Taiyuan030024 China College of Physics Taiyuan University of Technology Taiyuan030024 China Shanxi-Zheda Institute of Advanced Materials and ChemicalEngineering Taiyuan030024 China

A novel Brillouin frequency shift (BFS) extraction approach based on bidirectional integration is proposed and investigated for mitigating the fluctuations in Brillouin optical time domain reflectometer (BOTDR) system. The proposed method involves calculating the BFS through the forward and backward integrations of the original Brillouin gain spectrum (BGS) data. The findings from both simulations and experiments demonstrate that bidirectional integration achieves superior BFS accuracy compared to Lorentzian curve fitting. To further evaluate its performance, the root mean square error of BFS is measured under the different signal-to-noise ratios (SNRs) and frequency steps and the results show that bidirectional integration has higher tolerance for low SNR. Specifically, bidirectional integration achieves a BFS accuracy of 0.853 MHz under SNR of 5.22 dB and significantly reduces the measurement time by 85.86%. Additionally, the introduced coefficient k characterizes the influence on the BGS compression, with bidirectional integration exhibiting a narrower full width at half maximum of BGS (52.74 MHz) compared to Lorentzian curve fitting (67.45 MHz). © 2023, The Authors. All rights reserved.

关键词： Extraction

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Design of a Novel Autonomous Docking system With a Supporting Robotic Fish

Design of a Novel Autonomous Docking System With a Supportin...

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IEEE International Conference on Real-time Computing and Robotics (RCAR)

作者： Huijie Dong Chunyang Zhao Tiezhu Qiao Jian Wang Di Chen Yan Meng Junzhi Yu Ministry of Education Key Laboratory of Advanced Transducers and Intelligent Control System Taiyuan University of Technology Taiyuan China Institute of Automation Laboratory of Cognitive and Decision Intelligence for Complex System Chinese Academy of Sciences Beijing China Department of Advanced Manufacturing and Robotics College of Engineering State Key Laboratory for Turbulence and Complex Systems Peking University Beijing China College of Electronics and Information Engineering Guangdong Ocean University Zhanjiang China

Underwater supporting robots serving as a relay of energy supplements and communication for other underwater equipment are promising for ocean exploration, development, and protection. This paper proposes a novel autonomous docking system centered on a designed supporting robotic fish named ‘CourierFish’. Specifically, CourierFish is capable of docking with a surface dock station for supplying itself and docking with a seafloor platform for supporting equipment in the platform. A visual navigation scheme integrating LED and ArUco markers is presented for accurate localization. The control approach for docking motion is also illustrated. Simulations and aquatic experiments are performed to verify the feasibility of the proposed docking system. The obtained results lay a solid foundation for the construction of various underwater equipment and robot networks.

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Physical-layer key distribution using synchronous complex dynamics of DBR semiconductor lasers

arXiv

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arXiv 2023年

作者： Wang, Anbang Du, Yicheng Li, Qingtian Wang, Longsheng Jia, Zhiwei Qin, Yuwen Wang, Yuncai Institute of Advanced Photonics Technology School of Information Engineering Guangdong University of Technology Guangzhou51006 China Key Laboratory of Photonic Technology for Integrated Sensing and Communication Ministry of Education of China Guangdong University of Technology Guangzhou51006 China Guangdong Provincial Key Laboratory of Information Photonics Technology Guangdong University of Technology Guangzhou51006 China Key Lab of Advanced Transducers and Intelligent Control System Ministry of Education Taiyuan University of Technology Taiyuan030024 China College of Optoelectronics Taiyuan University of Technology Taiyuan030024 China

Common-signal-induced synchronization of semiconductor lasers with optical feedback inspired a promising physical key distribution with information-theoretic security and potential in high rate. A significant challenge is the requirement to shorten the synchronization recovery time for increasing key rate without sacrificing operation parameter space for security. Here, open-loop synchronization of wavelength-tunable multi-section distributed Bragg reflector (DBR) lasers is proposed as a solution for physical-layer key distribution. Experiments show that the synchronization is sensitive to two operation parameters, i.e., currents of grating section and phase section. Furthermore, fast wavelength-shift keying synchronization can be achieved by direct modulation on one of the two currents. The synchronization recovery time is shortened by one order of magnitude compared to close-loop synchronization. An experimental implementation is demonstrated with a final key rate of 5.98 Mbit/s over 160 km optical fiber distance. It is thus believed that fast-tunable multi-section semiconductor lasers opens a new avenue of high-rate physical-layer key distribution using laser synchronization. Copyright © 2023, The Authors. All rights reserved.

关键词： Synchronization

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