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MAINet: Modality-Aware Interaction Network for Medical Image Fusion

ACM Transactions on Multimedia Computing, Communications, and Applications 1000年

作者： Lisi Wei Libo Zhao Xiaoli Zhang College of Computer Science and Technology Jilin University China College of Artificial Intelligence and Big Data Hulunbuir University China and Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education Jilin University China College of Computer Science and Technology Jilin University China and Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education Jilin University China

Due to the limitations of imaging sensors, obtaining a medical image that simultaneously captures both functional metabolic data and structural tissue details remains a significant challenge in clinical diagnosis. To address this, Multimodal Medical Image Fusion (MMIF) has emerged as an effective technique for integrating complementary information from multimodal source images, such as CT, PET, and SPECT, which is critical for providing a comprehensive understanding of both anatomical and functional aspects of the human body. One of the key challenges in MMIF is how to exchange and aggregate this multimodal information. This paper rethinks MMIF by addressing the harmony of modality gaps and proposes a novel Modality-Aware Interaction Network (MAINet), which leverages cross-modal feature interaction and progressively fuses multiple features in graph space. Specifically, we introduce two key modules: the Cascade Modality Interaction (CMI) module and the Dual-Graph Learning (DGL) module. The CMI module, integrated within a multi-scale encoder with triple branches, facilitates complementary multimodal feature learning and provides beneficial feedback to enhance discriminative feature learning across modalities. In the decoding process, the DGL module aggregates hierarchical features in two distinct graph spaces, enabling global feature interactions. Moreover, the DGL module incorporates a bottom-up guidance mechanism, where deeper semantic features guide the learning of shallower detail features, thus improving the fusion process by enhancing both scale diversity and modality awareness for visual fidelity results. Experimental results on medical image datasets demonstrate the superiority of the proposed method over existing fusion approaches in both subjective and objective evaluations. We also validated the performance of the proposed method in applications such as infrared-visible image fusion and medical image segmentation.

关键词： Multimodal fusion Medical image fusion Cascade modality interaction Modality-awareness Graph convolutional network

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A Relation-Constraint Link Prediction Model for Dynamic knowledge Graphs with Entity Drift

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ACM Transactions on knowledge Discovery from data 1000年

作者： Xiulin Zheng Peipei Li Zan Zhang Jia Wu Xindong Wu Key Laboratory of Knowledge Engineering with Big Data (the Ministry of Education of China) Hefei University of Technology China and School of Computer Science and Information Engineering Hefei University of Technology China School of Computing Faculty of Science and Engineering Macquarie University Australia

knowledge Graphs (KGs) often suffer from incompleteness and this issue motivates the task of knowledge Graph Completion (KGC). Traditional KGC models mainly concentrate on static KGs with a fixed set of entities and relations, or dynamic KGs with temporal characteristics, faltering in their generalization to constantly evolving KGs with possible irregular entity drift. Thus, in this paper, we propose a novel link prediction model based on the embedding representation to handle the incompleteness of KGs with entity drift, termed as DCEL. Unlike traditional link prediction, DCEL could generate precise embeddings for drifted entity without imposing any regular temporal characteristic. The drifted entity is added into the KG with its links to the existing entity predicted in an incremental fashion with no requirement to retrain the whole KG for computational efficiency. In terms of DCEL model, it fully takes advantages of unstructured textual description, and is composed of four modules, namely MRC (Machine Reading Comprehension), RCAA (Relation Constraint Attentive Aggregator), RSA (Relation Specific Alignment) and RCEO (Relation Constraint Embedding Optimization). Specifically, the MRC module is first employed to extract short texts from long and redundant descriptions. Then, RCAA is used to aggregate the embeddings of textual description of drifted entity and the pre-trained word embeddings learned from corpus to a single text-based entity embedding while shielding the impact of noise and irrelevant information. After that, RSA is applied to align the text-based entity embedding to graph-based space to obtain the corresponding graph-based entity embedding, and then the learned embeddings are fed into the gate structure to be optimized based on the RCEO to improve the accuracy of representation learning. Finally, the graph-based model TransE is used to perform link prediction for drifted entity. Extensive experiments conducted on benchmark datasets in terms of evaluat

关键词： dynamic knowledge graph entity drift link prediction relation constraint

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Web-based Teamwork: Distributed Software Development Course under Covid-19

Web-based Teamwork: Distributed Software Development Course ...

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International Conference on Computer Science & education (ICCSE)

作者： Rui ZHANG Pedro Mestre Carlos Serodio Marília Prada Wenjuan GAO College of Computer Science and Technology Jilin University Key Lab of Symbolic Computation and Knowledge Engineering Chinese Ministry of Education Changchun China Centro Algoritmi University of Minho Guimaraes Portugal CITAB University of Tras-os-Montes and Alto Douro Vila Real Portugal Department of Social and Organizational Psychology Instituto Universitário de Lisboa (ISCTE-IUL) Lisboa Portugal Library of Changchun University Changchun China

ISBN: (数字)9781728172675

ISBN: (纸本)9781728172682

In a increasingly globalized world, it is very important to help students to acquire the hard and soft skills needed to cope with the challenges they will face when working in such environments. However, even though students find this subject interesting and volunteer for it, it is hard, even impossible to teach college students such a distributed fashion of teamwork. In this paper, a case study is provided to illustrate the methodology and experiences of a joint course, distributed software development, of multiple universities from Asia, Europe, North and South Americas. The results show that student can get the spirit, effective communication for such web-based teamwork environment and achieve software project development. The recent developments because of the Covid-19 pandemic are the facts that now students have to cooperate remotely with each other not only across continents but also inside their own city or country. It has increased the awareness of the need for this kind of training and effectively improved the interactions between team elements in different countries and improved the students' feeling of belonging to their team.

关键词： Software Software engineering Games Faces Teamwork Electronic mail Tools

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Computed tomography-based delta radiomics of tumor core_edge combination for systemic treatment response evaluation in pancreatic cancer

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Journal of Pancreatology 2024年第3期7卷 181-190页

作者： Xiang Li Na Lu Peijun Hu Yiwen Chen Liying Liu Xinyuan Liu Chengxiang Guo Wenbo Xiao Ke Sun Jingsong Li Xueli Bai Tingbo Liang Department of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalZhejiang University School of MedicineHangzhouChina Zhejiang Provincial Key Laboratory of Pancreatic Disease HangzhouChina Research Center for Healthcare Data Science Zhejiang LabHangzhou China Department of Radiology The First Affiliated HospitalZhejiang University School of MedicineHangzhouChina Department of Pathology The First Affiliated HospitalZhejiang University School of MedicineHangzhouChina Key Laboratory for Biomedical Engineering of Ministry of Education College of Biomedical Engineering and Instrument ScienceZhejiang UniversityHangzhouChina Zhejiang University Cancer Center HangzhouChina

Background:As a systemic disease,pancreatic cancer(PC)can be treated systemically to raise the R0 resection rate and enhance patient *** best ways to assess the treatment response to systemic treatment of patients with PC are still ***:A total of 122 PC patients were enrolled;25 of these patients were used as an independent testing *** to the pathologic response,PC patients were classified into the responder and nonresponder *** whole tumor,core,edge,and peritumoral were segmented from the enhanced computed tomography(CT)***-learning models were created by extracting the variations in radionics features before and after therapy(delta radiomics features).Finally,we compared the performance of models based on radiomics features,changes in tumor markers,and radiologic ***:The model based on the core(area under curve[AUC]=0.864)and edge features(AUC=0.853)showed better performance than that based on the whole tumor(AUC=0.847)or peritumoral area(AUC=0.846).Moreover,the tumor core_edge combination model(AUC=0.899)could better increase confidence in treatment response than using either of them *** accuracies of models based on changes in tumor markers and radiologic evaluation were relatively poorer than of the radiomics ***,Patients predicted to respond to therapy using the radiomics model showed a relatively longer overall survival(43 vs 27 months),although there were no significant differences(P=.063).Conclusions:The tumor core_edge combination delta radiomics model is an effective approach to evaluate pathologic response in PC patients with systemic treatment.

关键词： Computed tomography Delta radiomics Pancreatic cancer Pathologic response Systemic treatment

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Digital personal health libraries: A systematic literature review

arXiv

引用

arXiv 2020年

作者： Ding, Huitong Zhang, Chi An, Ning Zhang, Lingling Xie, Ning Alterovitz, Gil School of Computer Science and Information Engineering Hefei University of Technology Hefei China Key Laboratory of Knowledge Engineering with Big Data of Ministry of Education Hefei University of Technology Hefei China Department of Computer Science University of California Davis CA United States College of Nursing and Health Sciences University of Massachusetts Boston BostonMA United States Biomedical Cybernetics Laboratory Division of General Internal Medicine and Primary Care Department of Medicine Brigham and Women's Hospital BostonMA United States Department of Medicine Harvard Medical School BostonMA United States

Objective: This paper gives context on recent literature regarding the development of digital personal health libraries (PHL) and provides insights into the potential application of consumer health informatics in diverse clinical specialties. Materials and Methods: A systematic literature review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Here, 2,850 records were retrieved from PubMed and EMBASE in March 2020 using search terms: personal, health, and library. Information related to the health topic, target population, study purpose, library function, data source, data science method, evaluation measure, and status were extracted from each eligible study. In addition, knowledge discovery methods, including co-occurrence analysis and multiple correspondence analysis, were used to explore research trends of PHL. Results: After screening, this systematic review focused on a dozen articles related to PHL. These encompassed health topics such as infectious diseases, congestive heart failure, electronic prescribing. data science methods included relational database, information retrieval technology, ontology construction technology. Evaluation measures were heterogeneous regarding PHL functions and settings. At the time of writing, only one of the PHLs described in these articles is available for the public while the others are either prototypes or in the pilot stage. Discussion: Although PHL researches have used different methods to address problems in diverse health domains, there is a lack of an effective PHL to meet the needs of older adults. Conclusion: The development of PHLs may create an unprecedented opportunity for promoting the health of older consumers by providing diverse health information. Copyright © 2020, The Authors. All rights reserved.

关键词： Population statistics

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Toward a comprehensive hypothesis of oxygen-evolution reaction in the presence of iron and gold

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Journal of Energy Chemistry 2024年第2期89卷 172-183,I0005页

作者： Negah Hashemi Jafar Hussain Shah Cejun Hu Subhajit Nandy Pavlo Aleshkevych Sumbal Farid Keun Hwa Chae Wei Xie Taifeng Liu Junhu Wang Mohammad Mahdi Najafpour Department of Chemistry Institute for Advanced Studies in Basic Sciences(IASBS)Zanjan 45137-66731Iran Center for Advanced Mössbauer Spectroscopy Mössbauer Effect Data CenterDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina Key Lab of Advanced Energy Materials Chemistry(Ministry of Education) Renewable Energy Conversion and Storage CenterCollege of ChemistryNankai UniversityTianjin 300071China Advanced Analysis Center Korea Institute of Science and TechnologySeoul 02792Republic of Korea Institute of Physics Polish Academy of SciencesWarsaw 02-668Poland National and Local Joint Engineering Research Center for Applied Technology of Hybrid Nanomaterials Henan UniversityKaifeng 475004HenanChina Center of Climate Change and Global Warming Institute for Advanced Studies in Basic Sciences(IASBS)Zanjan 45137-66731Iran Research Center for Basic Sciences&Modern Technologies(RBST) Institute for Advanced Studies in Basic Sciences(IASBS)Zanjan 45137-66731Iran

This study investigates the effects of Fe on the oxygen-evolution reaction(OER)in the presence of *** distinct areas of OER were identified:the first associated with Fe sites at low overpotential(~330 mV),and the second with Au sites at high overpotential(~870 mV).Various factors such as surface Fe concentration,electrochemical method,scan rate,potential range,concentration,method of adding K_(2)Fe O_(4),nature of Fe,and temperature were varied to observe diverse behaviors during OER for Fe O_(x)H_(y)/*** amounts of Fe ions had a significant impact on OER,reaching a saturation point where the activity did not increase *** electronic interaction between Fe and Au ions was indicated by X-ray photoelectron spectroscopy(XPS)and electron paramagnetic resonance(EPR)*** situ visible spectroscopy confirmed the formation of Fe O_(4)^(2-)during *** situ Mossbauer and surfaceenhanced Raman spectroscopy(SERS)analyses suggest the involvement of Fe-based species as intermediates during the rate-determining step of OER.A lattice OER mechanism based on Fe O_(x)H_(y)was proposed for operation at low *** functional theory(DFT)calculations revealed that Fe oxide,Fe-oxide clusters,and Fe doping on the Au foil exhibited different activities and stabilities during *** study provides insights into the interplay between Fe and Au in OER,advancing the understanding of OER mechanisms and offering implications for the design of efficient electrocatalytic systems.

关键词： DFT calculation Fe/Au electrocatalysis Mechanism Oxygen evolution Water oxidation

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Disentangled Representation Learning with Transmitted Information Bottleneck

arXiv

引用

arXiv 2023年

作者： Dang, Zhuohang Luo, Minnan Jia, Chengyou Dai, Guang Wang, Jihong Chang, Xiaojun Wang, Jingdong The School of Computer Science and Technology The Ministry of Education Key Laboratory of Intelligent Networks and Network Security The Shaanxi Province Key Laboratory of Big Data Knowledge Engineering Xi'an Jiaotong University Shaanxi Xi’an710049 China The SGIT AI Laboratory Xi’an710048 China The State Grid Shaanxi Electric Power Company Ltd. State Grid Corporation of China Xi’an710048 China The School of Information Science and Technology University of Science and Technology of China Hefei230026 China Abu Dhabi United Arab Emirates Baidu Inc Beijing100085 China

Encoding only the task-related information from the raw data, i.e., disentangled representation learning, can greatly contribute to the robustness and generalizability of models. Although significant advances have been made by regularizing the information in representations with information theory, two major challenges remain: 1) the representation compression inevitably leads to performance drop;2) the disentanglement constraints on representations are in complicated optimization. To these issues, we introduce Bayesian networks with transmitted information to formulate the interaction among input and representations during disentanglement. Building upon this framework, we propose DisTIB (Transmitted Information Bottleneck for Disentangled representation learning), a novel objective that navigates the balance between information compression and preservation. We employ variational inference to derive a tractable estimation for DisTIB. This estimation can be simply optimized via standard gradient descent with a reparameterization trick. Moreover, we theoretically prove that DisTIB can achieve optimal disentanglement, underscoring its superior efficacy. To solidify our claims, we conduct extensive experiments on various downstream tasks to demonstrate the appealing efficacy of DisTIB and validate our theoretical analyses. Copyright © 2023, The Authors. All rights reserved.

关键词： Information theory

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Zero-knowledge Proof-based Practical Federated Learning on Blockchain

arXiv

引用

arXiv 2023年

作者： Xing, Zhibo Zhang, Zijian Li, Meng Liu, Jiamou Zhu, Liehuang Russello, Giovanni Asghar, Muhammad Rizwan The School of Computer Science The University of Auckland Auckland New Zealand The School of Cyberspace Science and Technology Beijing Institute of Technology Beijing100081 China Southeast Institute of Information Technology Beijing Institute of Technology Fujian351100 China Key Laboratory of Knowledge Engineering with Big Data Hefei University of Technology Ministry of Education School of Computer Science and Information Engineering Hefei University of Technology Anhui Hefei230601 China Anhui Province Key Laboratory of Industry Safety and Emergency Technology Intelligent Interconnected Systems Laboratory of Anhui Province Hefei University of Technology China The Department of Computer Science University of Surrey The School of Computer Science The University of Auckland Auckland New Zealand

Since the concern of privacy leakage extremely discourages user participation in sharing data, federated learning has gradually become a promising technique for both academia and industry for achieving collaborative learning without leaking information about the local data. Unfortunately, most federated learning solutions cannot efficiently verify the execution of each participant's local machine learning model and protect the privacy of user data, simultaneously. In this article, we first propose a Zero-knowledge Proof-based Federated Learning (ZKP-FL) scheme on blockchain. It leverages zero-knowledge proof for both the computation of local data and the aggregation of local model parameters, aiming to verify the computation process without requiring the plaintext of the local data. We further propose a Practical ZKP-FL (PZKP-FL) scheme to support fraction and non-linear operations. Specifically, we explore a Fraction-Integer mapping function, and use Taylor expansion to efficiently handle non-linear operations while maintaining the accuracy of the federated learning model. We also analyze the security of PZKP-FL. Performance analysis demonstrates that the whole running time of the PZKP-FL scheme is approximately less than one minute in parallel execution. Copyright © 2023, The Authors. All rights reserved.

关键词： Blockchain

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Probabilistic Graph Pattern Matching via Tumor knowledge Graph

引用

ACM Transactions on Probabilistic Machine Learning 1000年

作者： Lei Li Houdie Tu Zhenchao Tao Chenyang Bu Xindong Wu Key Laboratory of Knowledge Engineering with Big Data (the Ministry of Education of China) Hefei University of Technology Hefei 230601 China and School of Computer Science and Information Engineering Hefei University of Technology Hefei 230601 China School of Computer Science and Information Engineering Hefei University of Technology Hefei 230601 China School of Data Science University of Science and Technology of China Hefei 230052 China and West District of the First Affiliated Hospital of University of Science and Technology of China Hefei 230031 China Key Laboratory of Knowledge Engineering with Big Data (the Ministry of Education of China) Hefei University of Technology Hefei 230601 China

Graph Pattern Matching (GPM) entails the identification of subgraphs within a larger graph structure that either precisely mirror or closely parallel a predefined pattern graph. Despite the fact that research on GPM in large-scale graph data has been largely centered on social network analysis or enhancing the precision and efficiency of matching algorithms for expeditious subgraph retrieval, there is a noticeable absence of studies committed to probing GPM in medical domains. To rectify this shortcoming and probe the potential of GPM in clinical contexts, particularly in aiding patients with the selection of optimal tumor treatment plans, this paper introduces the concept of probabilistic graph pattern matching specifically modified for the Tumor knowledge Graph (TKG). We propose a multi-constraint graph pattern matching algorithm, hereinafter designated as TKG-McGPM, customized for the Tumor knowledge Graph. Through experimental verification, we establish that TKG-McGPM can facilitate more efficient and informed decision-making in tumor treatment planning.

关键词： Graph Pattern Matching Probabilistic Graph Pattern Matching Tumor knowledge Graph Monte Carlo Method

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Distilling the Unknown to Unveil Certainty

arXiv

引用

arXiv 2023年

作者： Zhao, Zhilin Cao, Longbing Zhang, Yixuan Lin, Kun-Yu Zheng, Wei-Shi The Data Science Lab School of Computing Macquarie University SydneyNSW2109 Australia The DataX Research Centre Macquarie University SydneyNSW2109 Australia The China-Austria Belt and Road Joint Laboratory on Artificial Intelligence and Advanced Manufacturing Hangzhou Dianzi University Zhejiang Hangzhou310005 China The School of Computer Science and Engineering Sun Yat-sen University Guangzhou510275 China The School of Computer Science and Engineering Key Laboratory of Machine Intelligence and Advanced Computing Ministry of Education Sun Yat-sen University Guangzhou510275 China

Out-of-distribution (OOD) detection is essential in identifying test samples that deviate from the in-distribution (ID) data upon which a standard network is trained, ensuring network robustness and reliability. This paper introduces OOD knowledge distillation, a pioneering learning framework applicable whether or not training ID data is available, given a standard network. This framework harnesses unknown OOD-sensitive knowledge from the standard network to craft a certain binary classifier adept at distinguishing between ID and OOD samples. To accomplish this, we introduce Confidence Amendment (CA), an innovative methodology that transforms an OOD sample into an ID one while progressively amending prediction confidence derived from the standard network. This approach enables the simultaneous synthesis of both ID and OOD samples, each accompanied by an adjusted prediction confidence, thereby facilitating the training of a binary classifier sensitive to OOD. Theoretical analysis provides bounds on the generalization error of the binary classifier, demonstrating the pivotal role of confidence amendment in enhancing OOD sensitivity. Extensive experiments spanning various datasets and network architectures confirm the efficacy of the proposed method in detecting OOD samples. Copyright © 2023, The Authors. All rights reserved.

关键词： Deep neural networks

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