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From photon momentum transfer to acceleration sensing

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arXiv 2024年

作者： Yang, Jianyu Li, Nan Pan, Yuyao Yang, Jing Chen, Zhiming Cai, Han Wang, Yuliang Han, Chuankun Chen, Xingfan Liu, Cheng Hu, Huizhu State Key Laboratory of Extreme Photonics and Instrumentation College of Optical Science and Engineering Zhejiang University Hangzhou310027 China Research Center for Advanced Computational Sensing and Intelligent Processing Zhejiang Lab Hangzhou310000 China Beijing Aerospace Control Instrument Research Institute Beijing100854 China

As a typical application of photon momentum transfer, optical levitation systems are known for their ideal isolation from mechanical dissipation and thermal noise. These characters offer extraordinary potential for acceleration precision sensing and have attracted extensive attention in both fundamental and applied physics. Although considerable improvements of optical levitation accelerometers has been reported, the dynamic testing of the sensing performance remains a crucial challenge before the utilization in practical application scenarios. In this work, we present a dual-beam optical levitation accelerometer and demonstrate the test with dynamic inputs for the first time. An acceleration sensing sensitivity of 0.1µg and a measurement range of 1g are achieved. These advancements solidify the potential of optical levitation accelerometer for deployment in practical domains, including navigation, intelligent driving, and industrial automation, building a bridge between the laboratory systems and real-world applications. Copyright © 2024, The Authors. All rights reserved.

关键词： Momentum transfer

SASA-Net: A spatial-aware self-attention mechanism for building protein 3D structure directly from inter-residue distances

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SASA-Net: A spatial-aware self-attention mechanism for build...

2021 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2021

作者： Gong, Tiansu Ju, Fusong Sun, Shiwei Bu, Dongbo Key Lab of Intelligent Information Processing Institute of Computing Technology Chinese Academy of Sciences Beijing100190 China University of Chinese Academy of Sciences Beijing100049 China Zhongke Big Data Academy Henan Zhengzhou450046 China

ISBN: (纸本)9781665401265

Protein structure prediction has achieved considerable progresses mainly due to the increased accuracy of inter-residue distance estimation and the application of deep learning *** of the distance-based ab initio prediction approaches adopt a two-step diagram: constructing a potential function based on the estimated inter-residue distances, and then build a 3D structure that minimizes the potential function. These approaches have proven very promising;however, they still suffer from several limitations, especially the inaccuracies incurred by the handcrafted potential ***, we present SASA-Net, a deep learning-based approach that directly learns protein 3D structure from the estimated inter-residue distances. Unlike the existing approach simply representing protein structures as coordinates of atoms, SASA-Net represents protein structures using pose of residues, i.e., the coordinate system of each individual residue in which all backbone atoms of this residue are fixed. The key element of SASA-Net is a spatial-aware self-attention mechanism, which is able to adjust a residue's pose according to all other residues' features and the estimated distances between residues. By iteratively applying the spatial-aware self-attention mechanism, SASA-Net continuously improves the structure and finally acquires a structure with high accuracy. Using the CATH35 proteins as representatives, we demonstrate that SASA-Net is able to accurately and efficiently build structures from the estimated inter-residue distances. The high accuracy and efficiency of SASA-Net enables an end-to-end neural network model for protein structure prediction through combining SASA-Net and an neural network for inter-residue distance prediction. Source code of SASA-Net is available at https://*** gongtiansu/SASA-Net/ © 2021 IEEE.

关键词： Proteins

OmniTracker: Unifying Object Tracking by Tracking-with-Detection

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arXiv 2023年

作者： Wang, Junke Chen, Dongdong Wu, Zuxuan Luo, Chong Dai, Xiyang Yuan, Lu Jiang, Yu-Gang Shanghai Key Lab of Intell. Info. Processing School of CS Fudan University China Shanghai Collaborative Innovation Center on Intelligent Visual Computing China Microsoft Cloud + AI China Microsoft Research Asia China

Object tracking (OT) aims to estimate the positions of target objects in a video sequence. Depending on whether the initial states of target objects are specified by provided annotations in the first frame or the categories, OT could be classified as instance tracking (e.g., SOT and VOS) and category tracking (e.g., MOT, MOTS, and VIS) tasks. Combing the advantages of the best practices developed in both communities, we propose a novel tracking-with-detection paradigm, where tracking supplements appearance priors for detection and detection provides tracking with candidate bounding boxes for association. Equipped with such a design, a unified tracking model, OmniTracker, is further presented to resolve all the tracking tasks with a fully shared network architecture, model weights, and inference pipeline. Extensive experiments on 7 tracking datasets, including LaSOT, TrackingNet, DAVIS16-17, MOT17, MOTS20, and YTVIS19, demonstrate that OmniTracker achieves on-par or even better results than both task-specific and unified tracking models. Copyright © 2023, The Authors. All rights reserved.

关键词： Network architecture

Single-cell Long Non-coding RNA Landscape of T Cells in Human Cancer Immunity

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Genomics, Proteomics & Bioinformatics 2021年第3期19卷 377-393页

作者： Haitao Luo Dechao Bu Lijuan Shao Yang Li Liang Sun Ce Wang Jing Wang Wei Yang Xiaofei Yang Jun Dong Yi Zhao Furong Li Translational Medicine Collaborative Innovation Center The Second Clinical Medical College(Shenzhen People’s Hospital)Jinan UniversityShenzhen 518020China Shenzhen Key Laboratory of Stem Cell Research and Clinical Transformation Shenzhen 518020China Integrated Chinese and Western Medicine Postdoctoral Research Station Jinan UniversityGuangzhou 510632China Bioinformatics Research Group Key Laboratory of Intelligent Information ProcessingAdvanced Computing Research CenterInstitute of Computing TechnologyChinese Academy of SciencesBeijing 100190China Department of Gastrointestinal Surgery The Second Clinical Medical College(Shenzhen People’s Hospital)Jinan UniversityShenzhen 518020China

The development of new biomarkers or therapeutic targets for cancer immunotherapies requires deep understanding of *** date,the complete landscape and systematic characterization of long noncoding RNAs(lncRNAs)in T cells in cancer immunity are ***,by systematically analyzing full-length single-cell RNA sequencing(scRNA-seq)data of more than 20,000 libraries of T cells across three cancer types,we provided the first comprehensive catalog and the functional repertoires of lncRNAs in human T ***,we developed a custom pipeline for de novo transcriptome assembly and obtained a novel lncRNA catalog containing 9433 *** increased the number of current human lncRNA catalog by 16%and nearly doubled the number of lncRNAs expressed in T *** found that a portion of expressed genes in single T cells were lncRNAs which had been overlooked by the majority of previous *** on metacell maps constructed by the MetaCell algorithm that partitions scRNA-seq datasets into disjointed and homogenous groups of cells(metacells),154 signature lncRNA genes were *** were associated with effector,exhausted,and regulatory T cell ***,84 of them were functionally annotated based on the co-expression networks,indicating that lncRNAs might broadly participate in the regulation of T cell *** findings provide a new point of view and resource for investigating the mechanisms of T cell regulation in cancer immunity as well as for novel cancer-immune biomarker development and cancer immunotherapies.

关键词： Long non-coding RNA Transcriptome assembly Metacell Immune regulation Functional annotation

PG-Attack: A Precision-Guided Adversarial Attack Framework Against Vision Foundation Models for Autonomous Driving

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arXiv 2024年

作者： Fu, Jiyuan Chen, Zhaoyu Jiang, Kaixun Guo, Haijing Gao, Shuyong Zhang, Wenqiang Shanghai Key Lab of Intelligent Information Processing School of Computer Science Fudan University China Shanghai Engineering Research Center of AI & Robotics Academy for Engineering & Technology Fudan University China Engineering Research Center of Robotics Ministry of Education Academy for Engineering & Technology Fudan University China

Vision foundation models are increasingly employed in autonomous driving systems due to their advanced capabilities. However, these models are susceptible to adversarial attacks, posing significant risks to the reliability and safety of autonomous vehicles. Adversaries can exploit these vulnerabilities to manipulate the vehicle’s perception of its surroundings, leading to erroneous decisions and potentially catastrophic consequences. To address this challenge, we propose a novel Precision-Guided Adversarial Attack (PG-Attack) framework that combines two techniques: Precision Mask Perturbation Attack (PMP-Attack) and Deceptive Text Patch Attack (DTP-Attack). PMP-Attack precisely targets the attack region to minimize the overall perturbation while maximizing its impact on the target object’s representation in the model’s feature space. DTP-Attack introduces deceptive text patches that disrupt the model’s understanding of the scene, further enhancing the attack’s effectiveness. Our experiments demonstrate that PG-Attack successfully deceives a variety of advanced multi-modal large models, including GPT-4V, Qwen-VL, and imp-V1. Additionally, we won First-Place in the CVPR 2024 Workshop Challenge: Black-box Adversarial Attacks on Vision Foundation Models‡ and codes are available at https://***/fuhaha824/PG-Attack. Copyright © 2024, The Authors. All rights reserved.

关键词： Autonomous vehicles

Data-consistent Unsupervised Diffusion Model for Metal Artifact Reduction

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Data-consistent Unsupervised Diffusion Model for Metal Artif...

2023 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2023

作者： Tong, Zhan Wu, Zhan Yang, Yang Mao, Weilong Wang, Shijie Li, Yinsheng Chen, Yang Southeast University Laboratory of Image Science and Technology Nanjing210096 China Southeast University Ministry of Education Key Laboratory of Computer Network and Information Integration Nanjing210096 China Chinese Academy of Sciences Research Center for Medical Artificial Intelligence Shenzhen Institutes of Advanced Technology Shenzhen518055 China School of Computer Science and Engineering Key Lab. of New Generation Artificial Intelligence Technology and Its Interdisciplinary Applications Jiangsu Provincial Joint International Research Laboratory of Medical Information Processing The Laboratory of Image Science and Technology Nanjing210096 China

ISBN: (纸本)9798350337488

Computed Tomography (CT) is an imaging technique widely used in clinical diagnosis. However, high-attenuation metallic implants result in the obstruction of low-energy Xrays and further lead to metal artifacts in the reconstructed CT images. Deep supervised model-based metal artifact reduction(MAR) approaches are limited in clinical applications due to the difficulty in obtaining paired artifact-affected and artifactfree data. Furthermore, these model-based methods lack the consideration of data consistency in the sinogram-domain to perform exact metal trace inpainting. To address these challenges, we propose a Data-consistent unsupErVised diffusiOn model for meTal artifact rEDuction, called DEVOTED-Net. First, DEVOTED-Net leverages prior knowledge to guide the conditional diffusion model for fine-grained metal trace inpainting. Second, an unsupervised MAR framework is designed in the reverse process for the unknown metal traces restoration in the sinogram domain. Third, to further enhance the sinogram-domain data consistency, physics-based consistency constraint loss including conjugateray consistency loss and accumulation-ray consistency loss is designed. Extensive experiments are carried out to verify the performance of our algorithm on the publicly available dataset and clinical experimental dataset. This efficient, accurate, and reliable MAR approach holds great potential in clinics. © 2023 IEEE.

关键词： computed tomography deep unsupervised learning denoising diffusion probabilistic model Metal artifact reduction physics-based consistency constraint

Long-Tailed Multi-label Classification with Noisy label of Thoracic Diseases from Chest X-Ray

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Long-Tailed Multi-Label Classification with Noisy Label of T...

IEEE International Symposium on Biomedical Imaging

作者： Haoran Lai Qingsong Yao Zhiyang He Xiaodong Tao S. Kevin Zhou School of Biomedical Engineering Division of Life Sciences and Medicine University of Science and Technology of China Hefei P.R. China Suzhou Institute for Advanced Research University of Science and Technology of China Suzhou P.R. China Key Lab of Intelligent Information Processing of Chinese Academy of Sciences (CAS) Institute of Computing Technology CAS Beijing China Medical Business Department iFlytek Co. Ltd Hefei China

ISBN: (数字)9798350313338

ISBN: (纸本)9798350313345

Chest X-rays (CXR) often reveal rare diseases, demanding precise diagnosis. However, current computer-aided diagnosis (CAD) methods focus on common diseases, leading to inadequate detection of rare conditions due to the absence of comprehensive datasets. To overcome this, we present a novel benchmark for long-tailed multi-label classification in CXRs, encapsulating both common and rare thoracic diseases. Our approach includes developing the "LTML-MIMIC-CXR" dataset, an augmentation of MIMIC-CXR with 26 additional rare diseases. We propose a baseline method for this classification challenge, integrating adaptive negative regularization to address negative logits' over-suppression in tail classes, and a large loss reconsideration strategy for correcting noisy labels from automated annotations. Our evaluation on LTML- MIMIC-CXR demonstrates significant advancements in rare disease detection. This work establishes a foundation for robust CAD methods, achieving a balance in identifying a spectrum of thoracic diseases in CXRs. Access to our code and dataset is provided at: https://***/laihaoran/LTML-MIMIC-CXR.

关键词： Design automation Annotations MIMICs Pipelines Tail Computer aided diagnosis Noise measurement

Spatiotemporal Activity Modeling via Hierarchical Cross-Modal Embedding : Extended Abstract

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Spatiotemporal Activity Modeling via Hierarchical Cross-Moda...

International Conference on Data Engineering

作者： Yang Liu Xiang Ao Linfeng Dong Chao Zhang Jin Wang Qing He Key Lab of Intelligent Information Processing of Chinese Academy of Sciences (CAS) Institute of Computing Technology CAS Beijing China University of Chinese Academy of Sciences Beijing China Zhejiang University Hangzhou China College of Computing Georgia Tech United States Megagon Labs Mountain View United States

With the ever-increasing urbanization process, modeling people’s spatiotemporal activities from their online traces has become a crucial task. State-of-the-art methods for this task rely on cross-modal embedding, which maps items from different modalities (e.g., location, time, text) into the same latent space. Despite their inspiring results, existing cross-modal embedding methods merely capture co-occurrences between items without modeling their high-order interactions. In this paper, we first construct the user interaction graph and the activity graph from raw data records and propose a hierarchical cross-modal embedding method that takes the high-order relationships into consideration. We introduce both inter-record and intra-record meta-graph structures, which enable learning distributed representations that preserve high-order proximities across graphs from different layers. Our empirical experiments on three real-world datasets demonstrate that our method not only outperforms state-of-the-art methods for spatiotemporal activity prediction but also captures cross-modal proximity at a finer granularity.

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Resolving Task Confusion in Dynamic Expansion Architectures for Class Incremental Learning

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arXiv 2022年

作者： Huang, Bingchen Chen, Zhineng Zhou, Peng Chen, Jiayin Wu, Zuxuan Shanghai Key Lab of Intelligent Information Processing School of Computer Science Fudan University China Shanghai Collaborative Innovation Center on Intelligent Visual Computing China University of Maryland College ParkMD United States

The dynamic expansion architecture is becoming popular in class incremental learning, mainly due to its advantages in alleviating catastrophic forgetting. However, task confusion is not well assessed within this framework, e.g., the discrepancy between classes of different tasks is not well learned (i.e., inter-task confusion, ITC), and certain priority is still given to the latest class batch (i.e., old-new confusion, ONC). We empirically validate the side effects of the two types of confusion. Meanwhile, a novel solution called Task Correlated Incremental Learning (TCIL) is proposed to encourage discriminative and fair feature utilization across tasks. TCIL performs a multi-level knowledge distillation to propagate knowledge learned from old tasks to the new one. It establishes information flow paths at both feature and logit levels, enabling the learning to be aware of old classes. Besides, attention mechanism and classifier re-scoring are applied to generate more fair classification scores. We conduct extensive experiments on CIFAR100 and ImageNet100 datasets. The results demonstrate that TCIL consistently achieves state-of-the-art accuracy. It mitigates both ITC and ONC, while showing advantages in battle with catastrophic forgetting even no rehearsal memory is reserved. 1 Copyright © 2022, The Authors. All rights reserved.

关键词： Distillation