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arXiv 2020年

作者： Abdar, Moloud Pourpanah, Farhad Hussain, Sadiq Rezazadegan, Dana Liu, Li Ghavamzadeh, Mohammad Fieguth, Paul Cao, Xiaochun Khosravi, Abbas Rajendra Acharya, U. Makarenkov, Vladimir Nahavandi, Saeid Deakin University Australia College of Mathematics and Statistics Guangdong Key Lab. of Intelligent Information Processing Shenzhen University Shenzhen518060 China Dibrugarh University Dibrugarh India Department of Computer Science and Software Engineering Swinburne University of Technology Melbourne Australia Center for Machine Vision and Signal Analysis University of Oulu Oulu Finland Google research United States Department of Systems Design Engineering University of Waterloo Waterloo Canada State Key Laboratory of Information Security Institute of Information Engineering Chinese Academy of Sciences Beijing China Department of Electronics and Computer Engineering Ngee Ann Polytechnic Clementi Singapore Department of Computer Science University of Quebec in Montreal MontrealQC Canada

—Uncertainty quantification (UQ) plays a pivotal role in the reduction of uncertainties during both optimization and decision making, applied to solve a variety of real-world applications in science and engineering. Bayesian approximation and ensemble learning techniques are two of the most widely-used UQ methods in the literature. In this regard, researchers have proposed different UQ methods and examined their performance in a variety of applications such as computer vision (e.g., self-driving cars and object detection), image processing (e.g., image restoration), medical image analysis (e.g., medical image classification and segmentation), natural language processing (e.g., text classification, social media texts and recidivism risk-scoring), bioinformatics, etc. This study reviews recent advances in UQ methods used in deep learning, investigates the application of these methods in reinforcement learning, and highlight the fundamental research challenges and directions associated with the UQ field. Copyright © 2020, The Authors. All rights reserved.

关键词： Image segmentation

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Speaker Recognition Based on the Improved Double-Threshold Endpoint Algorithm and Multistage Vector Quantization 9

Speaker Recognition Based on the Improved Double-Threshold E...

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2017 9th IEEE International Conference on Communication Software and Networks (ICCSN 2017)

作者： Jun Zhu Jingjing Zhang Qiang Chen Peipei Tu Key Lab of Intelligent Computing and Signal Processing Ministry of Education School of Electronics and Information Engineering Anhui University

ISBN: (纸本)9781509038237;9781509038220

The traditional double-threshold endpoint detection method has the phenomenon of missing detection. Therefore, the speech recognition(SR) system based on vector quantization(VQ) in this paper proposes an improved algorithm for this phenomenon, which effectively avoids the problem of missing detection. Then, Mel Frequency Cepstral Coefficients(MFCC) is used to extract the characteristic parameters of the speech signal, and the multistage vector quantization is used to quantify the characteristic parameters. Experimental results show that, the proposed algorithm improves the recognition rate of the text-independent speaker recognition system by 8.7%, and it also confirms that the longer the training speech is, the higher the recognition rate will be.

关键词： the multistage vector quantization MFCC double-threshold endpoint detection method missing detection characteristic parameters

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用于糖尿病培训的大型语言模型:一项前瞻性研究（英文）

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Science Bulletin 2025年第6期 934-942页

作者：李灏萱江泽铧管洲榆包玉倩刘月星胡婷婷李佳佳刘茹涵吴量程棣纪宏伟王勇王亚星 Carol Y.Cheung 郑颖丰王继红李震吴卫兵 Cynthia Ciwei Lim Yong Mong Bee Hong Chang Tan Elif I.Ekinci David C.Klonoff Justin B.Echouffo-Tcheugui Nestoras Mathioudakis Leonor Corsino Rafael Simó Charumathi Sabanayagam Gavin Siew Wei Tan 程景煜黄天荫李华婷蔡淳毛丽娟 Lee-Ling Lim 覃宇宗盛斌贾伟平 Shanghai University of Sport School of Clinical Medicine Beijing Tsinghua Changgung Hospital Tsinghua Medicine Tsinghua University Beijing Visual Science and Translational Eye Research Institute(BERI) Tsinghua Medicine Tsinghua University Shanghai Belt and Road International Joint Laboratory of Intelligent Prevention and Treatment for Metabolic Diseases Department of Computer Science and Engineering School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Department of Endocrinology and Metabolism Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai Diabetes Institute Shanghai Clinical Center for Diabetes MoE Key Lab of Artificial Intelligence Artificial Intelligence Institute Shanghai Jiao Tong University Department of Cardiology the Affiliated Hospital of Qingdao University CEMS NCMIS HCMS MADIS Academy of Mathematics and Systems Science Chinese Academy of Sciences School of Mathematics University of Chinese Academy of Sciences Chinese Academy of Sciences Key Laboratory of Systems Health Science of Zhejiang Province School of Life Science Hangzhou Institute for Advanced Study University of Chinese Academy of Sciences Beijing Institute of Ophthalmology Beijing Tongren Hospital Capital Medical University Beijing Ophthalmology and Visual Sciences Key Laboratory Department of Ophthalmology and Visual Sciences The Chinese University of Hong Kong State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-sen University Guangdong Provincial Key Laboratory of Ophthalmology and Visual ScienceGuangdong Provincial Clinical Research Center for Ocular Diseases Department of Renal Medicine Singapore General Hospital Sing Health-Duke Academic Medical Centre Department of Endocrinology Singapore General Hospital Department of Endocrinology Austin Health Department of Medicine The University of Melbourne(Austin Health) Australian Centre for Accelerating Diabetes Innovations(ACADI) The Univ

Diabetes poses a considerable global health challenge, with varying levels of diabetes knowledge among healthcare professionals, highlighting the importance of diabetes training. Large Language Models(LLMs)provide new insights into diabetes training, but their performance in diabetes-related queries remains uncertain, especially outside the English language like Chinese. We first evaluated the performance of ten LLMs: Chat GPT-3.5, Chat GPT-4.0, Google Bard, Lla MA-7B, Lla MA2-7B, Baidu ERNIE Bot, Ali Tongyi Qianwen, Med GPT, Huatuo GPT, and Chinese Lla MA2-7B on diabetes-related queries, based on the Chinese National Certificate Examination for Primary Diabetes Care in China(NCE-CPDC) and the English Specialty Certificate Examination in Endocrinology and Diabetes of Membership of the Royal College of Physicians of the United Kingdom. Second, we assessed the training of primary care physicians(PCPs) without and with the assistance of Chat GPT-4.0 in the NCE-CPDC examination to ascertain the reliability of LLMs as medical assistants. We found that Chat GPT-4.0 outperformed other LLMs in the English examination, achieving a passing accuracy of 62.50%, which was significantly higher than that of Google Bard, Lla MA-7B, and Lla MA2-7B. For the NCE-CPFC examination, Chat GPT-4.0, Ali Tongyi Qianwen, Baidu ERNIE Bot, Google Bard, Med GPT, and Chat GPT-3.5 successfully passed, whereas Lla MA2-7B, Huatuo GPT,Chinese LLa MA2-7B, and Lla MA-7B failed. Chat GPT-4.0(84.82%) surpassed all PCPs and assisted most PCPs in the NCE-CPDC examination(improving by 1%–6.13%). In summary, LLMs demonstrated outstanding competence for diabetes-related questions in both the Chinese and English language, and hold great potential to assist future diabetes training for physicians globally.

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Out-of-domain Detection for Natural Language Understanding in Dialog Systems

arXiv

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arXiv 2019年

作者： Zheng, Yinhe Chen, Guanyi Huang, Minlie Beijing100102 China The Institute for Artificial Intelligence State Key Lab of Intelligent Technology and Systems Beijing National Research Center for Information Science and Technology Department of Computer Science and Technology Tsinghua University Beijing100084 China The Department of Information and Computing Sciences Utrecht University Utrecht3584 CC Netherlands

Natural Language Understanding (NLU) is a vital component of dialogue systems, and its ability to detect Out-of-Domain (OOD) inputs is critical in practical applications, since the acceptance of the OOD input that is unsupported by the current system may lead to catastrophic failure. However, most existing OOD detection methods rely heavily on manually labeled OOD samples and cannot take full advantage of unlabeled data. This limits the feasibility of these models in practical applications. In this paper, we propose a novel model to generate high-quality pseudo OOD samples that are akin to IN-Domain (IND) input utterances and thereby improves the performance of OOD detection. To this end, an autoencoder is trained to map an input utterance into a latent code. Moreover, the codes of IND and OOD samples are trained to be indistinguishable by utilizing a generative adversarial network. To provide more supervision signals, an auxiliary classifier is introduced to regularize the generated OOD samples to have indistinguishable intent labels. Experiments show that these pseudo OOD samples generated by our model can be used to effectively improve OOD detection in NLU. Besides, we also demonstrate that the effectiveness of these pseudo OOD data can be further improved by efficiently utilizing unlabeled data. Copyright © 2019, The Authors. All rights reserved.

关键词： Speech processing

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Jacobi Spectral Collocation Method Based on Lagrange Interpolation Polynomials for Solving Nonlinear Fractional Integro-Differential Equations

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Advances in Applied Mathematics and Mechanics 2018年第6期10卷 1440-1458页

作者： Xingfa Yang Yin Yang Yanping Chen Jie Liu State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body Hunan UniversityChangsha 410082HunanChina Hunan Key Laboratory for Computation and Simulation in Science and Engineering Key Laboratory of Intelligent Computing&Information Processing of Ministry of EducationSchool of Mathematics and Computational ScienceXiangtan UniversityXiangtan 411105HunanChina School of Mathematical Sciences South China Normal UniversityGuangzhou 510631GuangdongChina Center for Research on Leading Technology of Special Equipment School of Mechanical and Electric EngineeringGuangzhou UniversityGuangzhou 510006GuangdongChina

In this paper,we study a class of nonlinear fractional integro-differential equations,the fractional derivative is described in the Caputo *** the properties of the Caputo derivative,we convert the fractional integro-differential equations into equivalent integral-differential equations of Volterra type with singular kernel,then we propose and analyze a spectral Jacobi-collocation approximation for nonlinear integro-differential equations of Volterra *** provide a rigorous error analysis for the spectral methods,which shows that both the errors of approximate solutions and the errors of approximate fractional derivatives of the solutions decay exponentially in L^(∞)-norm and weighted L^(2)-norm.

关键词： Spectral method nonlinear fractional derivative Volterra integro-differential equations Caputo derivative

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Efficient and adaptive kernelization for nonlinear max-margin multi-view learning

arXiv

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arXiv 2019年

作者： Du, Changying Jia He, B. Du, Changde Zhuang, Fuzhen He, Qing Long, Guoping Huawei Noah's Ark Lab Beijing100085 China Key Laboratory of Intelligent Information Processing Institute of Computing Technology Chinese Academy of Sciences Beijing100190 China Institute of Software Chinese Academy of Sciences Beijing100190 China Research Center for Brain-Inspired Intelligence Institute of Automation CAS Beijing China University of Chinese Academy of Sciences Beijing100049 China

Existing multi-view learning methods based on kernel function either require the user to select and tune a single predefined kernel or have to compute and store many Gram matrices to perform multiple kernel learning. Apart from the huge consumption of manpower, computation and memory resources, most of these models seek point estimation of their parameters, and are prone to overfitting to small training data. This paper presents an adaptive kernel nonlinear max-margin multi-view learning model under the Bayesian framework. Specifically, we regularize the posterior of an efficient multi-view latent variable model by explicitly mapping the latent representations extracted from multiple data views to a random Fourier feature space where max-margin classification constraints are imposed. Assuming these random features are drawn from Dirichlet process Gaussian mixtures, we can adaptively learn shift-invariant kernels from data according to Bochners theorem. For inference, we employ the data augmentation idea for hinge loss, and design an efficient gradient-based MCMC sampler in the augmented space. Having no need to compute the Gram matrix, our algorithm scales linearly with the size of training set. Extensive experiments on real-world datasets demonstrate that our method has superior performance. Copyright © 2019, The Authors. All rights reserved.

关键词： Bayesian networks

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Harmonized-Multinational qEEG norms (HarMNqEEG)

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NEUROIMAGE 2022年 256卷 119190-119190页

作者： Li, Min Wang, Ying Lopez-Naranjo, Carlos Hu, Shiang Reyes, Ronaldo Cesar Garcia Paz-Linares, Deirel Areces-Gonzalez, Ariosky Hamid, Aini Ismafairus Abd Evans, Alan C. Savostyanov, Alexander N. Calzada-Reyes, Ana Villringer, Arno Tobon-Quintero, Carlos A. Garcia-Agustin, Daysi Yao, Dezhong Dong, Li Aubert-Vazquez, Eduardo Reza, Faruque Razzaq, Fuleah Abdul Omar, Hazim Abdullah, Jafri Malin Galler, Janina R. Ochoa-Gomez, John F. Prichep, Leslie S. Galan-Garcia, Lidice Morales-Chacon, Lilia Valdes-Sosa, Mitchell J. Trondle, Marius Zulkifly, Mohd Faizal Mohd Rahman, Muhammad Riddha Bin Abdul Milakhina, Natalya S. Langer, Nicolas Rudych, Pavel Koenig, Thomas Virues-Alba, Trinidad A. Lei, Xu Bringas-Vega, Maria L. Bosch-Bayard, Jorge F. Valdes-Sosa, Pedro Antonio [a]The Clinical Hospital of Chengdu Brain Science Institute MOE Key Lab for Neuroinformation School of Life Science and Technology University of Electronic Science and Technology of China Chengdu China [b]Cuban Center for Neurocience La Habana Cuba [c]McGill Centre for Integrative Neuroscience Ludmer Centre for Neuroinformatics and Mental Health Montreal Neurological Institute Canada [d]Department of Neurosciences School of Medical Sciences Universiti Sains Malaysia Universiti Sains Malaysia Health Campus Kota Bharu Kelantan 16150 Malaysia [e]Brain and Behaviour Cluster School of Medical Sciences Universiti Sains Malaysia Health Campus Kota Bharu Kelantan 16150 Malaysia [f]Hospital Universiti Sains Malaysia Universiti Sains Malaysia Health Campus Kota Bharu Kelantan 16150 Malaysia [g]Humanitarian Institute Novosibirsk State University Novosibirsk 630090 Russia [h]Laboratory of Psychophysiology of Individual Differences Federal State Budgetary Scientific Institution Scientific Research Institute of Neurosciences and Medicine Novosibirsk 630117 Russia [i]Laboratory of Psychological Genetics at the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences Novosibirsk 630090 Russia [j]University of Pinar del Río “Hermanos Saiz Montes de Oca” Pinar del Río Cuba [k]Department of Neurology Max Planck Institute for Human Cognitive and Brain Sciences Leipzig Germany [l]Department of Cognitive Neurology University Hospital Leipzig Leipzig Germany [m]Center for Stroke Research Charité-Universitätsmedizin Berlin Berlin Germany [n]Grupo Neuropsicología y Conducta - GRUNECO Faculty of Medicine Universidad de Antioquia Colombia [o]Research Department Institución Prestadora de Servicios de Salud IPS Universitaria Colombia [p]The Cuban center aging longevity and health Havana Cuba [q]Research Unit of NeuroInformation Chinese Academy of Medical Sciences Chengdu 2019RU035 China [r]School of Electrical Engineering Zhengzhou University Zhengzhou 4500

This paper extends frequency domain quantitative electroencephalography (qEEG) methods pursuing higher sensitivity to detect Brain Developmental Disorders. Prior qEEG work lacked integration of cross-spectral information omitting important functional connectivity descriptors. Lack of geographical diversity precluded accounting for site-specific variance, increasing qEEG nuisance variance. We ameliorate these weaknesses. (i) Create lifespan Riemannian multinational qEEG norms for cross-spectral tensors. These norms result from the HarMNqEEG project fostered by the Global Brain Consortium. We calculate the norms with data from 9 countries, 12 devices, and 14 studies, including 1564 subjects. Instead of raw data, only anonymized metadata and EEG cross spectral tensors were shared. After visual and automatic quality control, developmental equations for the mean and standard deviation of qEEG traditional and Riemannian DPs were calculated using additive mixed-effects models. We demonstrate qEEG "batch effects " and provide methods to calculate harmonized z-scores. (ii) We also show that harmonized Riemannian norms produce z-scores with increased diagnostic accuracy predicting brain dysfunction produced by malnutrition in the first year of life and detecting COVID induced brain dysfunction. (iii) We offer open code and data to calculate different individual z-scores from the HarMNqEEG dataset. These results contribute to developing bias-free, low-cost neuroimaging technologies applicable in various health settings.

关键词： Quantitative EEG EEG cross-spectrum Riemannian geometry Batch effects Z-score Harmonization Malnutrition Covid induced brain dysfunction Developmental Brain Chart

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de novo sequencing with mirror image protease of LysargiNase and trypsin for large scale proteomics

de novo sequencing with mirror image protease of LysargiNase...

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中国生物化学与分子生物学会第十二届全国会员代表大会暨2018年全国学术会议

作者：徐平杨皓李衍常赵明治张俊令王一豪迟浩贺思敏 National Center for Protein Sciences Beijing Key Lab of Intelligent Information Processing of Chinese Academy of Sciences (CAS) Institute of Computing TechnologyCAS

De novo peptide sequencing for an individual pure protein has improved remarkably with the progress of mass spectrometry but there still exists incomplete peptide fragmentation and indistingushiable series of fragmented ions,which interrupted the interpretation of amino acid sequence of *** is even worse at proteome ***,we developed a series of high efficiency proteases,including LysargiNase with super activity and acetylated trypsin with high *** advantage of these two enzymes,we developed a novel algorithm,pNovoM for automated de novo sequencing of the mirrored peptides generated from the digestion of trypsin and LysargiNase *** combination of paired mirror image spectra results nearly complete series of product ions,which facilitate the de novo sequencing on both of purified protein and proteasome samples.

关键词： de novo sequencing proteomics mirror enzyme LysargiNase

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ADAM CHALLENGE: DETECTING AGE-RELATED MACULAR DEGENERATION FROM FUNDUS IMAGES

arXiv

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arXiv 2022年

作者： Fang, Huihui Li, Fei Fu, Huazhu Sun, Xu Cao, Xingxing Lin, Fengbin Son, Jaemin Kim, Sunho Quellec, Gwenole Matta, Sarah Shankaranarayana, Sharath M. Chen, Yi-Ting Wang, Chuen-Heng Shah, Nisarg A. Lee, Chia-Yen Hsu, Chih-Chung Xie, Hai Lei, Baiying Baid, Ujjwal Innani, Shubham Dang, Kang Shi, Wenxiu Kamble, Ravi Singhal, Nitin Wang, Ching-Wei Lo, Shih-Chang Orlando, José Ignacio Bogunović, Hrvoje Zhang, Xiulan Xu, Yanwu The ADAM Challenge State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science Guangzhou China Intelligent Healthcare Unit Baidu Inc. Beijing China The Institute of High Performance Computing Agency for Science Technology and Research Singapore CONICET Yatiris lab of Pladema Institute Tandil Argentina Department of Ophthalmology and Optometry Medical University of Vienna Vienna Austria VUNO Inc Seoul Korea Republic of Inserm UMR 1101 BrestF-29200 France Univ Bretagne Occidentale BrestF-29200 France Zasti India Pvt. Ltd. India Graphen.Inc Muen Biomedical and Optoelectronics Technologies Inc Taiwan Department of Electrical Engineering Indian Institute of Technology Rajasthan Jodhpur India Department of Electrical Engineering National United University Taiwan Institute of Data Science Department of Statistics National Cheng Kung University Taiwan Shenzhen University Shenzhen China SGGS Institute of Engineering and Technology Nanded India Suzhou Tisu Information Technology Co. Ltd China AIRA Matrix Mumbai India Graduate Institute of Biomedical Engineering National Taiwan University of Science and Technology Taiwan

Age-related macular degeneration (AMD) is the leading cause of visual impairment among elderly in the world. Early detection of AMD is of great importance, as the vision loss caused by this disease is irreversible and permanent. Color fundus photography is the most cost-effective imaging modality to screen for retinal disorders. Cutting edge deep learning based algorithms have been recently developed for automatically detecting AMD from fundus images. However, there are still lack of a comprehensive annotated dataset and standard evaluation benchmarks. To deal with this issue, we set up the Automatic Detection challenge on Age-related Macular degeneration (ADAM), which was held as a satellite event of the ISBI 2020 conference. The ADAM challenge consisted of four tasks which cover the main aspects of detecting and characterizing AMD from fundus images, including detection of AMD, detection and segmentation of optic disc, localization of fovea, and detection and segmentation of lesions. As part of the ADAM challenge, we have released a comprehensive dataset of 1200 fundus images with AMD diagnostic labels, pixel-wise segmentation masks for both optic disc and AMD-related lesions (drusen, exudates, hemorrhages and scars, among others), as well as the coordinates corresponding to the location of the macular fovea. A uniform evaluation framework has been built to make a fair comparison of different models using this dataset. During the ADAM challenge, 610 results were submitted for online evaluation, with 11 teams finally participating in the onsite challenge. This paper introduces the challenge, the dataset and the evaluation methods, as well as summarizes the participating methods and analyzes their results for each task. In particular, we observed that the ensembling strategy and the incorporation of clinical domain knowledge were the key to improve the performance of the deep learning models. © 2022, CC BY-NC-ND.

关键词： Cost effectiveness

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A Pilot Allocation Scheme for TDD Massive MIMO System Enabled Het Net 9

A Pilot Allocation Scheme for TDD Massive MIMO System Enable...

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2017 9th IEEE International Conference on Communication Software and Networks (ICCSN 2017)

作者： Hui Zhi Quan Yuan Jun Zhu Yanjun Hu Key Lab of Intelligent Computing and Signal Processing (Anhui University) Ministry of Education School of Electronics and Information Engineering Anhui University

ISBN: (纸本)9781509038237;9781509038220

A pilot allocation(PA) scheme is propose to reduce pilot contamination for time division duplex(TDD) massive multiple-input multiple-output(MIMO) system enabled twotier heterogeneous cellular network(Het Net). In order to reduce inter-tier interference during channel estimation, proposed scheme assigns mutually orthogonal pilots between macro-cells and small-cells, and pilots are reused among macro-cells with different pilot reuse factors. Comprehensive analyses and simulations of uplink average signal to interference plus noise ratio(SINR) and average achievable ergodic rate for the proposed scheme are developed. Simulation results show that the proposed PA scheme can reduce pilot contamination and improve the SINR and ergodic rate at base stations(BSs). In addition, the average SINR increases when pilot reuse factor grows, which shows the benefit of the proposed scheme. The average ergodic rate first becomes larger and then becomes smaller when pilot reuse factor becomes larger, which means the large number of pilot symbols limits the increase of ergodic rate.

关键词： massive MIMO HetNet pilot allocation scheme SINR ergodic rate

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