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检索条件"机构=Key Lab. of RF Circuits and Systems"

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A drop-shaped deterministic lateral displacement microfluidic chip for accurate size-based circulating tumor cells separation

A drop-shaped deterministic lateral displacement microfluidi...

引用

2024 International Conference on Next Generation Electronics and Photonics, INGEP 2024

作者： Xiang, Rikui Chen, Jin Sun, Jingjing Huang, Xiwei Ministry of Education Key Lab of RF Circuits and Systems Hangzhou Dianzi University China

Cells released from the primary tumor to the peripheral blood are referred to as circulating tumor cells (CTCs). The detection of CTCs at an early stage can be instructive to the implementation of follow-up treatments. However, due to the rarity of CTCs in the peripheral blood, it is urgent to develop an accurate CTC separation method. Here, we propose a drop-shaped deterministic lateral displacement (DLD) microfluidic chip to accurately separate and enumerate CTCs with cost-effective and simple testing procedures. The drop-shaped DLD enhanced performance for the separation of white blood cells (WBCs) and CTCs, which achieved CTCs high separation efficiency (>99%) and >50% CTCs purity. Our drop-shaped DLD microfluidic chip offers a lab.l-free and highly reliable CTCs separation solution and is promising to low-cost point-of-care CTCs detection. © Published under licence by IOP Publishing Ltd.

关键词： Microfluidics

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An optimized MOPSA algorithm for highly accurate deterministic lateral displacement microfluidic sorting chip design

An optimized MOPSA algorithm for highly accurate determinist...

引用

2024 International Conference on Next Generation Electronics and Photonics, INGEP 2024

作者： Chen, Jin Xiang, Rikui Huang, Xiwei Ministry of Education Key Lab of RF Circuits and Systems Hangzhou Dianzi University China

Deterministic lateral displacement (DLD) sorting is a passive sorting technology. Due to the advantages of small volume and high accuracy, the DLD devices have been used in many applications. The critical diameter (Dc) value of the DLD device depends on the geometric structure of the internal post array. However, the existing empirical formula cannot match all types of post-arrays. Achieving the desired Dc value typically involves multiple iterative processes, leading to increased lab.r and time costs. In this paper, we propose an optimized trajectory prediction algorithm based on the original MOPSA, which considers the impact of fluidic pressure on particle trajectories. The method is to stretch the 2D physical field space into 3D, the particle expands from a 2D circle into a 3D ball on the pressure analysis. The net pressure on the particle is calculated, and the displacement of the particle is predicted by combining Newton's second law and the displacement formula. A DLD device with Dc=10.6 µm was designed using this optimized algorithm and fabricated. It is verified by separation of 10 µm and 11 µm polystyrene particles. The test results were consistent with the simulation results. Compared with the empirical formula and the original MOPSA, this optimized algorithm can improve the prediction accuracy of particle trajectories in DLD devices. © Published under licence by IOP Publishing Ltd.

关键词： Trajectories

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Cost-effective scanning digital microscopic system for wide field-of-view and high-resolution biomedical imaging

Cost-effective scanning digital microscopic system for wide ...

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2024 International Conference on Next Generation Electronics and Photonics, INGEP 2024

作者： Lin, Siru Lv, Zhihang Huang, Xiwei Ministry of Education Key Lab of RF Circuits and Systems Hangzhou Dianzi University China

Microscopes serve as indispensable tools for exploring the microcosm and conducting biological detection. However, traditional microscopes fail to balance the field of view and resolution, limiting wide-field imaging capabilities. Here, we propose a low-cost, wide-field, high-resolution digital microscopy imaging system, providing high-quality and versatile microscopy tools for budget-constrained lab.ratories. The design of this system is based on the low-cost mechanical scanning and positioning platform provided by a computer numerical control (CNC) router architecture. The use of a transmitted light structure ensures uniform field illumination for both bright-field and fluorescence microscopy. Utilizing a 20× objective lens, this microscopy system achieves clear imaging of 1µm particles and rapidly acquires hundreds of microscopic images for subsequent stitching, thus achieving high-resolution wide-field imaging in both bright-field and fluorescence modes. The system integrates the advantages of wide-field, high-resolution imaging, and high-throughput image acquisition, providing a cost-effective solution for wide-field microscopy. © Published under licence by IOP Publishing Ltd.

关键词： Budget control

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The cell elastic modulus sensing based on surface acoustic wave devices

The cell elastic modulus sensing based on surface acoustic w...

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2024 International Conference on Next Generation Electronics and Photonics, INGEP 2024

作者： Ye, Boya Sun, Lingling Ministry of Education Key Lab. of RF Circuits and Systems College of Electron. and Info. Hangzhou Dianzi University Hangzhou310018 China

Elastic modulus is an important parameter to reflect the status of the cell. In this work, the elastic modulus of liquid and cancer cell were studied based on the delay line type surface acoustic wave (SAW) device. Firstly, the finite element method (FEM) was used to analyse and design the sensor, a cavity was etched on the propagation path. After the acoustic wave transmit through the cavity, the transmission parameter was disturbed by the material in the cavity. The phase shift of the S21 parameter of the SAW sensor was used to detect the elastic modulus of liquid or cell in the cavity. © Published under licence by IOP Publishing Ltd.

关键词： Acoustic waves

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Design of Quasi-Absorptive Ultra-Wideband Bandpass Filter Based on Stub Resonator

Design of Quasi-Absorptive Ultra-Wideband Bandpass Filter Ba...

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2023 International Applied Computational Electromagnetics Society Symposium, ACES-China 2023

作者： Feng, Zhang-Zhe Ma, Yi-Hao Zhao, Wen-Sheng School of Electronics and Information Hangzhou Dianzi University Moe Key Lab of Rf Circuits and Systems Hangzhou310018 China

ISBN: (纸本)9781733509657

In this paper, a design method for quasi- absorptive ultra-wideband (UWB) bandpass filter (BPF) that can achieve quasi-reflectionless at both ports is proposed. The absorptive UWB BPF consists of a reflective UWB BPF and two resistively terminated bandstop filters (BSF), which are connected on both ports of the reflective UWB BPF. Within the passband, the BSF sections are considered as open circuit due to their high input impedance, allowing energy transmission through the reflective BPF. In the stopband, the input impedance of the BSF sections match the source impedance, resulting in the absorption of energy reflected by the reflective BPF. To demonstrate the design, an absorptive UWB BPF are designed and simulated. © 2023 Applied Computational Electromagnetics Society (ACES).

关键词： Notch filters

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A Single-Notch Ultra-Wideband Bandpass Filter Based on Bow-Tie Cells

A Single-Notch Ultra-Wideband Bandpass Filter Based on Bow-T...

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2023 IEEE International Workshop on Electromagnetics: Applications and Student Innovation Competition, iWEM 2023

作者： Xie, Yu-Feng Ma, Yi-Hao Zhao, Wen-Sheng Hangzhou Dianzi University Moe Key Lab of Rf Circuits and Systems School of Electronics and Information Hangzhou310018 China

ISBN: (纸本)9798350336740

This paper presents a highly efficient ultra-wideband (UWB) bandpass filter using coplanar waveguide (CPW) technology. The design employs bow-tie cells to achieve four transmission poles and one transmission zero. A step impedance resonator is introduced for further performance enhancement, and it contributes an additional transmission zero at low frequencies and optimizes the stopband. A T-shaped short-circuit stub is used to create a trap frequency band with deep attenuation, effectively blocking the ITU8.0 frequency band centered at 8.2 GHz. The proposed filter features a passband range from 3.7 GHz to 9.6 GHz, an insertion loss less than 0.8 dB, and a return loss greater than 20 dB. Additionally, the filter exhibits high selectivity, with a 30 dB skirt factor of 0.88 and a wide stopband up to 17.7 GHz, where S21 is below -20 dB. © 2023 IEEE.

关键词： Coplanar waveguides

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An Absorptive Common-Mode Stripline Filter for High-Speed Digital systems

An Absorptive Common-Mode Stripline Filter for High-Speed Di...

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2023 International Applied Computational Electromagnetics Society Symposium, ACES-China 2023

作者： Chen, Yu-Bin Ma, Yi-Hao Wang, Da-Wei Zhao, Wen-Sheng School of Electronics and Information Hangzhou Dianzi University Moe Key Lab of Rf Circuits and Systems Hangzhou310018 China

ISBN: (纸本)9781733509657

This paper presents an absorptive common-mode stripline filter, which consists of two reflective common-mode filter (CMF) units and one absorptive CMF unit. For differential-mode (DM) signal, the filter is equivalent to an all-pass filter, while for common-mode (CM) signal, it exhibits band-stop characteristics. The filter can achieve more than 90% energy absorption for CM signal in the frequency range from 4.84 GHz to 6.11 GHz, while the DM signal could pass through from DC to 10.32 GHz. © 2023 Applied Computational Electromagnetics Society (ACES).

关键词： All-pass filters

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Broadband Absorptive Common-Mode Filter Based on H-Shaped Defect Ground Structure

Broadband Absorptive Common-Mode Filter Based on H-Shaped De...

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2023 IEEE International Workshop on Electromagnetics: Applications and Student Innovation Competition, iWEM 2023

作者： Lv, Jun-Chen Ma, Yi-Hao Zhao, Wen-Sheng Hangzhou Dianzi University Moe Key Lab of Rf Circuits and Systems School of Electronics and Information Hangzhou310018 China

ISBN: (纸本)9798350336740

A broadband absorptive common-mode (CM) filter based on an H-shaped defect ground structure (DGS) is proposed in this paper. The filter suppresses CM noise by periodically etching H-shaped defect structures with different sizes along the return path of the differential lines, while maintaining the integrity of the differential signal. It achieves a CM suppression over 20 dB within the frequency range of 1.83 GHz to 6.38 GHz. Further, the filter achieves absorption by embedding a resistor in the etched structure to dissipate reflected noise. By operating within the frequency ranges of 2.06 GHz to 3.14 GHz and 4.83 GHz to 6.88 GHz, the CM noise absorption efficiency can surpass 90%, effectively eradicating CM noise in the Wi-Fi frequency bands of 2.4 GHz and 5 GHz. The size of the filter is approximately 0.17λg ×0.41λg © 2023 IEEE.

关键词： Defected ground structures

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Semi-supervised Regression Model for Eye Diagram Estimation of High Bandwidth Memory (HBM) Silicon Interposer

Semi-supervised Regression Model for Eye Diagram Estimation ...

引用

2023 International Applied Computational Electromagnetics Society Symposium, ACES-China 2023

作者： Li, Guo-Sheng Mao, Chang-Sheng Zhao, Wen-Sheng School of Electronics and Information Hangzhou Dianzi University Moe Key Lab of Rf Circuits and Systems Hangzhou310018 China

ISBN: (纸本)9781733509657

This paper presents a semi-supervised regression model for accurate eye height and eye width estimation of high bandwidth memory (HBM) silicon interposer channels. The model combines a channel characteristic-based deep neural network with a co-trained convolution neural network. For verification, the proposed model was applied to the stripline channels of an HBM silicon interposer. The root-mean-square errors (RMSE) of the predicted results of eye width and eye height are 4.95 mV and 7.32 ps. © 2023 Applied Computational Electromagnetics Society (ACES).

关键词： Deep neural networks

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A compact broadband amplifier for 5G FR2 in 65nm CMOS

A compact broadband amplifier for 5G FR2 in 65nm CMOS

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2023 International Applied Computational Electromagnetics Society Symposium, ACES-China 2023

作者： Wu, Qingyan Wen, Jincai School of Electronics and Information Engineering Hangzhou Dianzi University Hangzhou China Ministry of Education Hangzhou Dianzi University Key Lab. of Rf Circuits and Systems Hangzhou China

ISBN: (纸本)9781733509657

In this paper, a compact broadband amplifier is realized based on 65nm CMOS technology. The three differential CMOS pairs adopt the common source (CS) structure, rely on the capacitance neutralization technology and use the transformer for impedance transformation to achieve ultra-wideband matching. The simulation results show that in FR2 frequency band (24.26 - 52.6GHz), the output gain of the amplifier is 17±2.5dB, the DC power consumption is 45mW, the supply voltage is 1V, and the core circuit area is 0.11mm2. © 2023 Applied Computational Electromagnetics Society (ACES).

关键词： Millimeter waves

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