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A coaxially extruded heterogeneous core-shell fiber with Schwann cells and neural stem cells

Regenerative Biomaterials 2020年第2期7卷 131-139页

作者： Xinda Li Dezhi Zhou Zhizhong Jin Hongqing Chen Xuanzhi Wang Xinzhi Zhang Tao Xu Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing Department of Mechanical EngineeringTsinghua UniversityBeijing 100084People’s Republic of China Key Laboratory for Advanced Materials Processing Technology Ministry of EducationDepartment of Mechanical EngineeringTsinghua UniversityBeijing 100084People’s Republic of China Department of Neurosurgery the First Hospital of China Medical UniversityShenyang 110122People’s Republic of China Department of Neurosurgery Xijing HospitalFourth Military Medical UniversityXi’an 710032People’s Republic of China Department of Neurosurgery the First Affiliated Hospital of Wannan Medical CollegeWuhu 241001People’s Republic of China East China Institute of Digital Medical Engineering Shangrao 334000People’s Republic of China Medprin Regenerative Medical Technologies Co. LtdShenzhen 518102People’s Republic of China Department of Precision Medicine and Healthcare Tsinghua Berkeley Shenzhen InstituteShenzhen 518055People’s Republic of China

Cellular therapies play a critical role in the treatment of spinal cord injury(SCI).Compared with cell-seeded conduits,fully cellular grafts have more similarities with autografts,and thus might result in better regeneration *** this study,we fabricated Schwann cell(SC)-neural stem cell(NSC)core–shell alginate hydrogel fibers in a coaxial extrusion *** rat SC line RSC96 and mouse NSC line NE-4C were used in this *** cellular components were achieved in the core portion and the relative spatial positions of these two cells partially mimic the construction of nerve fibers in *** were demonstrated to express more genes of neurotrophic factors in alginate *** proliferation and differentiation tendency of NSCs was observed when they were co-cultured with *** model has strong potential for application in SCI repair.

关键词： coaxial extrusion neural stem cell Schwann cell

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Mobility Analysis of Novel Deployable Mechanism Based on Tetrahedral Element

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Jixie Gongcheng Xuebao/Journal of Mechanical Engineering 2019年第12期55卷 9-18页

作者： Guo, Jinwei Xu, Yundou Liu, Wenlan Yao, Jiantao Zhao, Yongsheng Parallel Robot and Mechatronic System Laboratory of Hebei Province Yanshan University Qinhuangdao066004 China Key Laboratory of Advanced Forging & Stamping Technology and Science of Ministry of National Education Yanshan University Qinhuangdao066004 China

The DOF (degree of freedom) analysis is carried out for the symmetrical and asymmetrical composite unit mechanism based on the 3RR-3URU tetrahedral element and the deployable composite unit structure based on the 3UU-3URU tetrahedral basic element. Firstly, the DOF and properties of 3RR-3URU tetrahedral basic element are analyzed based on the link-demolishing and equivalent method. The basic elements are combined into symmetric 3RR-3URU composite unit and asymmetric 3RR-3URU composite unit. Then, the structures and the geometric constraints of the two composite units are analyzed, and the screw theory and G-K formula are applied to analyze the DOF of the two composite units. Secondly, in view of the problem that the composite unit based on 3RR-3URU cannot satisfy the large deployable antenna mechanism, the 3UU-3URU basic element and its composite unit are proposed, and the DOF of which are obtained according to G-K formula. Finally, the simulation models of three composite units are established, and the ADAMS simulation software is used to simulate the motion of the three combined units. The simulation results verify the correctness of the DOF analysis. The results provide an important theoretical basis for the design and analysis of tetrahedral deployable antenna mechanism. © 2019 Journal of Mechanical Engineering.

关键词： Degrees of freedom (mechanics)

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Teeth profile parameter design and transmission property analysis of external generating wave movable teeth transmission

Teeth profile parameter design and transmission property ana...

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19th International Conference of Fluid Power and Mechatronic Control Engineering 2018

作者： Yi, Yali Gao, Yunfei Wei, Rui Jin, Herong College of Mechanical Engineering Yanshan University Qinhuangdao China Key Laboratory of Advanced Forging and Stamping Technology and Science Ministry of Education of China Yanshan University Qinhuangdao China Parallel Robot and Mechatronic System Laboratory of Hebei Province Yanshan University Qinhuangdao China

A highly efficient integrated transmission unit - external generating wave movable teeth transmission − was proposed and two kinds of typical transmission types were researched. Fixed and moving coordinate systems were established based on movable teeth transmission theory. On the basis of the profile of a wave generator, the teeth profile equations of ring gear were deduced by using the transform matrix and profile enveloping principle. The effects of the teeth number of the ring gear, generating wave coefficient, and tooth profile coefficient on the profile of the ring gear were investigated. The formula for calculating curvature radius of the ring gear was given. The pressure angle formulas were deduced, and the change rule of the pressure angle extremum was researched to obtain a continuous transmission condition. The relationship between design parameters and performance effect was analysed based on the analysis of the curvature and pressure angle. The results show that the transmission precision reached 97.67%, and the proper design parameters could guarantee transmission performance. Those researches lay a theoretical foundation for the design and application of an external generating wave movable teeth title. © 2019 Institution of Engineering and technology. All rights reserved.

关键词： Gear teeth

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The microstructural dependence of ionic transport in bicontinuous nanoporous metal

arXiv

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arXiv 2021年

作者： Wang, Congcheng Tsang, Anson Xiao, Diwen Xu, Yuan Yang, Shida Liu, Ling-Zhi Zheng, Qiang Liu, Pan Jin, Hai-Jun Chen, Qing Department of Mechanical and Aerospace Engineering The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong The Energy Institute The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong George W. Woodruff School of Mechanical Engineering Georgia Institute of Technology AtlantaGA United States Department of Chemistry The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong Shenyang National Laboratory for Materials Science Institute of Metal Research Chinese Academy of Sciences Shenyang China State Key Laboratory of Metal Matrix Composites Shanghai Key Laboratory of Advanced High-Temperature Materials and Precision Forming School of Materials Science and Engineering Shanghai Jiao Tong University Shanghai China

Ionic transports in nanopores hold the key to unlocking the full potential of bi-continuous nanoporous (NP) metals as advanced electrodes in electrochemical devices. The precise control of the uniform NP metal structures also provides us a unique opportunity to understand how complex structures determine transports at nanoscales. For NP Au from the dealloying of a Ag-Au alloy, we can tune the pore size in the range of 13 nm to 2.4 µm and the porosity between 38% and 69% via isothermal coarsening. For NP Ag from the reduction-induced decomposition of AgCl, we can control additionally its structural hierarchy and pore orientation. We measure the effective ionic conductivities of 1 M NaClO4 through these NP metals as membranes, which range from 7% to 44% of that of a free solution, corresponding to calculated pore tortuosity's between 2.7 and 1.3. The tortuosity of NP Au displays weak dependences on both the pore size and the porosity, consistent with the observed self-similarity in the coarsening, except for those of pores 2reduction with these two low-tortuosity NP Ag's, demonstrating the significance of the structure-transport relationships for designing functional NP metals. © 2021, CC BY.

关键词： Chlorine compounds

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Profile Division and Programmatic Modeling of Tetrahedral Truss Deployable Antennas

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Zhongguo Jixie Gongcheng/China Mechanical Engineering 2019年第12期30卷 1400-1408页

作者： Han, Bo Xu, Yundou Guo, Luyao Zhang, Shuo Yao, Jiantao Zhao, Yongsheng Parallel Robot and Mechatronic System Laboratory of Hebei Province Yanshan University QinhuangdaoHebei066004 China Key Laboratory of Advanced Forging & Stamping Technology and Science of Ministry of Education Yanshan University QinhuangdaoHebei066004 China

Tetrahedral truss deployable antennas were studied, and a simple profile division method was proposed. Based on MATLAB and SOLIDWORKS, a programmatic modeling method was proposed. Custom software development for SOLIDWORKS was completed by VBA programming language, and visual operation interfaces were designed. Two examples of deployable antenna mechanisms were used to verify the correctness of the profile division method and the programmatic modeling processes. The proposed profile division method proposed herein is simple and the quality of the profile mesh is good, the method of programmatic modeling is convenient and quick to model the antenna mechanisms, and the overall design efficiency is greatly improved. © 2019, China Mechanical Engineering Magazine Office. All right reserved.

关键词： MATLAB

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Game Scene Construction for Lower Limb Rehabilitation Robot Based on Virtual Reality

Game Scene Construction for Lower Limb Rehabilitation Robot ...

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International Conference on Electromechanical Control technology and Transportation (ICECTT)

作者： Yongfei Feng Di Jin Qianjun Shao Jianye Niu Luige Vladareanu Hongbo Wang Faculty of Mechanical Engineering & Mechanics Ningbo University Ningbo China Hebei Key Laboratory of Robot Sensing and Human-Robot Interaction Hebei University of Technology Tianjin China Robotics and Mechatronic Department Institute of Solid Mechanics of the Romanian Academy Bucharest Romania Parallel Robot and Mechatronic System Laboratory of Hebei Province and Key Laboratory of Advanced Forging & Stamping Technology and Science of Ministry of Education Yanshan University Qinhuangdao China

ISBN: (数字)9781728199283

ISBN: (纸本)9781728199290

At present, the number of patients with lower extremity dysfunction is increasing year by year. However, traditional rehabilitation training cannot meet the needs of patients for rehabilitation training. Rehabilitation robot is a good solution to train patients instead of the rehabilitation physician. Based on clinical practice experience, a lower limb rehabilitation training system based on virtual reality (VR) is designed, which combined the VR technology and rehabilitation evaluation program to improve the rehabilitation efficiency of patients. According to the functional requirements of the lower limb rehabilitation robot (LLR-RO), the construction of rehabilitation robot control system and sensor system is completed. Based on the Unity3D development environment, a VR scenes of space shooting is planned and created for rehabilitation training VR technology which enables patients to complete the training process while maintaining a pleasant mood. Through the software and hardware debugging, the feasibility, data transmission capability of VR-based remote rehabilitation training system and the synchronization performance of VR scenes and rehabilitation robots are verified. In the future, more virtual reality scenes will be studied to adapt to patients of different genders and ages.

关键词： Games Training Rehabilitation robotics Space vehicles Legged locomotion Aircraft Aerospace electronics

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Cross-coupling control of contour error for five-axis linkage machining

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Journal of Physics: Conference Series 2021年第6期1748卷

作者： Baoying Peng Mingpeng Hou Milan Zhang State Key Laboratory of Advanced Forming Technology and Equipment China Academy of Machinery Science and Technology Beijing China The department Of Mechanical Engineering Beijing Information Science & Technology University Beijing China

The accuracy of five-axis linkage machining is influenced by many factors, such as linear axis errors, tool rotation errors, contour trajectory changes, milling force changes, and five-axis parameters do not mismatch. To improve the machining accuracy, the kinematical model of five-axis linkage with B-C double swing head is derived on the basis of RTCP (Rotation tool center point). The following errors of five axis coupled form contour error calculation model is proposed and a cross-coupled controller is designed. Choosing the curve of impeller as an example, a simulation model of five-axis linkage machining is established. Simulation results show that the cross-coupling controller designed for can improve the machining contour accuracy of the five-axis machining effectively.

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On the Origin of Capacity Increase in Rechargeable Magnesium Batteries with Manganese Oxide Cathodes and Copper Metal Current Collectors

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Angewandte Chemie 2024年第5期137卷

作者： Zhao Li Yi Li Yang Zhan Xiaodong Lin Yingying Yao Tianshuo Zhao Fengzhan Sun Hao Xu Zhewen Ma Wei Zhang Yanling Xue Xiaolong Li Alexandru Vlad Jianxin Zou National Engineering Research Center of Light Alloy Net Forming State Key Laboratory of Metal Matrix Composite Center of Hydrogen Science School of Materials Science and Engineering Shanghai Jiao Tong University 200240 Shanghai China Institute of Condensed Matter and Nanosciences Université Catholique de Louvain B-1348 Louvain-la-Neuve Belgium Institute for Clean Energy & Advanced Materials School of Materials and Energy Southwest University 400715 Chongqing China State Key Laboratory of Advanced Processing and Recycling of Nonferrous Metals School of Materials Science and Engineering Lanzhou University of Technology 730050 Lanzhou China Shanghai Synchrotron Radiation Facility Shanghai Advanced Research Institute Chinese Academy of Sciences 201204 Shanghai China

Rechargeable magnesium batteries (RMBs), with Cu as positive electrode current collector (CC), typically display a gradual capacity increase with cycling. Whereas the origin of this was suggested in gradual active material electro-activation, the fact that this is prevalent in many positive electrode material systems remains unexplained. Herein, we elucidate the underlying mechanism through a series of multiscale joint operando X-ray characterizations, including operando synchrotron X-ray diffraction and imaging technology. We select a series of manganese oxides as benchmark positive electrodes and find that no magnesium ions are stored within the lattices of these materials, despite an apparent cell capacity increase with cycling. The origin of capacity increase is rooted in the gradual electrochemical corrosion of metallic Cu, release of Cu(I, II) species in electrolyte, and their subsequent redox activity, resulting in apparent electrode capacity gains. Furthermore, the shuttle and redox speciation of Cu ions trigger the irreversible depletion of both the Cu CC (or any other source) and the magnesium metal, ultimately leading to cell failure. Our work suggests the need to reconsider the appropriateness of using Cu as a positive electrode CC for RMBs.

关键词： Magnesium metal batteries synchrotron X-ray characterizations X-ray imaging operando X-ray characterizations copper current collector

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Evolution analysis of key mechanical properties during the forming process of JCOE and JCOC pipes and its influence on collapse failure

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Ocean Engineering 2025年 335卷

作者： Shaocong Qi Guoyi Shen Xihai Liu Wanlin Cheng Ruixue Zhai Qingdang Meng Jun Zhao Gaochao Yu Key Laboratory of Advanced Forging & Stamping Technology and Science (Yanshan University) Ministry of Education of China Qinhuangdao 066004 China School of Mechanical Engineering Yanshan University Qinhuangdao 066004 China Hebei Huayang Steel Pipe Co. Ltd Cangzhou 061403 China Hebei Yadu Pipeline Equipment Co. Ltd Cangzhou 061300 China Department of Mechanical Engineering Imperial College London London SW7 2AZ UK

The LSAW pipes are main trunk pipes for offshore oil and gas energy development. Enhancing the buckling resistance performance of submarine pipes and accurately evaluating its collapse pressure are research priorities. This study analyzes for the first time the evolution of residual stress and compressive strength during the full-process forming of JCOE and JCOC pipes, and reveals the influence mechanism of mechanical properties on collapse. The yield plateau phenomenon and variable elastic modulus behavior of X65 steel were described by modifying Chaboche model. A theoretical model for the evolution of mechanical properties during JCO forming, expansion, and compression processes were established. The full-process forming and collapse simulations were conducted. The experimental and theoretical yield stresses have good consistency. The calibration ratio and t / D ratio are key factors affecting the yield stress and residual stress. Compared with JCOE pipes, JCOC pipes have lower residual stress but higher compressive strength. Within calibration ratio range of ±0.4 % to ±1.0 %, residual stress is the main factor affecting collapse. As the calibration ratio increases, residual stress improves and compressive yield stress becomes a key factor. This study is of great significance for the forming and buckling analysis of pipelines.

关键词： Residual stresses

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Janus Evaporators with Ultrathin and Non-Tortuous Channels: High Efficiency, Long-Term and Stable-Floating Solar Desalination

SSRN

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SSRN 2025年

作者： Zhang, Liang Guo, Chuhuan Liang, Minhui Fang, Yi Zhang, Jiaru Xi, Man Bian, Fenggang You, Jichun Shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai201800 China University of Chinese Academy of Sciences Beijing100049 China College of Material Chemistry and Chemical Engineering Hangzhou Normal University Hangzhou311121 China Shanghai Advanced Research Institute Chinese Academy of Sciences Shanghai201800 China Key Laboratory of Yarn Materials Forming and Composite Processing Technology of Zhejiang Province Jiaxing University Jiaxing314001 China

In this work, a self-floating Janus evaporator based on poly(l-lactic acid) (PLLA) shape memory membranes with uniform vertically penetrative channels (SMEUVs) was prepared for solar-driven interfacial evaporation. The asymmetric wettability and the pore structure with non-tortuous ultrathin channels (~4.6 μm) play important roles in the evaporation performance. Firstly, the superhydrophobic layer of the evaporator enables the membrane to stay out of the water to achieve efficient light absorption while the hydrophilic layer in the water ensures continuous water pumping. Secondly, the vertically penetrative channels not only shorten the distance for water transport and vapor diffusion but also promote the rapid reflux of salt ions back into the bulk seawater. Finally, the combination of these structures effectively reduces the space between the membrane and the water, enhancing its attachment and minimizing the likelihood of being displaced by vortex and wave forces. As a result, the optimal specimen (SMEUVs coated with carbon black) exhibits an impressively high evaporation rate of 1.41 kg·m⁻²·h⁻¹ with energy efficiency over 92 % under 1-sun irradiation in a 3.5 wt% NaCl solution, along with remarkable long-term stability by maintaining continuous operation for over 200 hours even in a 25 wt% NaCl solution and sustaining stable evaporation performance in fluctuating water. Our results are significant for the design, fabrication and application of solar-driven interfacial evaporation system. © 2025, The Authors. All rights reserved.

关键词： Desalination

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