检索结果-内蒙古大学图书馆

Temperature-sensitive Micelles as Artificial Chaperones for Insulin Protection

Chinese Journal of Polymer Science 2025年第2期43卷 350-359页

作者： Jia-Wen Chen Yan Xiao Mei-Dong Lang Shanghai Key Laboratory of Advanced Polymeric Materials Key Laboratory for Ultrafine Materials of Ministry of EducationSchool of Materials Science and EngineeringEast China University of Science and TechnologyShanghai200237China

Insulin is an essential and versatile protein taking part in the control of blood glucose levels and protein ***,under prolonged storage or high temperature stress,insulin tends to unfold and aggregate into toxic amyloid fibrils,leading to loss of physiological *** by natural chaperones,a series of temperature-sensitive polycaprolactone-based micelles were designed to prevent insulin from *** micelles were fabricated through the self-assembly of amphiphilic copolymers of methoxy poly(ethylene glycol)-poly(4-diethylformamide caprolactone-co-caprolactone)(mPEG_(17)-P(DECL-co-CL)),which had a regular spherical morphology with particle sizes of about 100 *** addition,the lower critical solution temperature(LCST)of the micelles could be tuned to 9 and 29℃by changing the ratio of DECL to *** from the temperature-sensitivity of DECL segment,the binding ability of micelles to insulin could be modulated by changing the *** LCST,micelles effectively inhibited insulin aggregation and protected it from thermal inactivation due to the strong binding ability between the hydrophobic segment DECL and *** LCST,DECL segment returned to hydrophilic and bound weakly with insulin,leading to the release of insulin and assisting in its recovery of secondary ***,these temperature-sensitive micelles provided an effective strategy for insulin protection.

关键词： Temperature-sensitive Insulin Micelles Chaperones

来源：评论

学校读者我要写书评

暂无评论

Subsurface deformation mechanism and the interplay relationship between strength–ductility and fretting wear resistance during fretting of a high-strength titanium alloy

引用

Friction 2024年第10期12卷 2259-2280页

作者： Yanlin TONG Ke HUA Haoyang XIE Yue CAO Zhuobin HUANG Zhenpeng LIANG Xiaolin LI Hongxing WU Haifeng WANG State Key Laboratory of Solidification Processing Center of Advanced Lubrication and Seal MaterialsNorthwestern Polytechnical UniversityXi’an 710072China

Fretting wear damage of high-strength titanium fasteners has caused a large number of disastrous ***,it is believed that both high strength and excellent ductility can reduce fretting wear ***,whether strength and ductility are contradictory or not and their appropriate matching strategy under the external applied normal stress(Fw)are still confusing ***,by analyzing the subsurface-microstructure deformation mechanism of several samples containing variousαprecipitate features,for the first time,we design strategies to improve fretting damage resistance under different matching relation between Fw and the tensile strength of materials(Rm).It is found that when Fw is greater than Rm or Fw is nearly equivalent to Rm,the deformation mechanism mainly manifests as serious grain fragmentation ofβandαGB *** deformation in large areas only reduces damage to a limited *** is crucial to improve the strength to resist cracking and wear,but it is of little significance to improve the ***,when Fw is far less than Rm,coordinated deformation ability reflected by ductility plays a more important *** deformation mechanism mainly manifests as localized deformation ofβandαGB constituents(kinking induced by twinning and spheroidizing).A unique composite structure of nano-grained/lamellar layer and localized deformation transition layer reduces fretting damage by five times compared with a single nanograined *** when the strength is great enough,improving the plasticity can reduce *** study can provide a principle for designing fretting damage resistant alloys.

关键词： fretting wear high-strength titanium alloy microstructures subsurface deformation

来源：评论

学校读者我要写书评

暂无评论

Effect of rolling-texture intensity on fretting damage and subsurface deformation behavior in a high-strength titanium alloy

引用

Journal of materials Science & technology 2024年第29期196卷 200-214页

作者： Yanlin Tong Ke Hua Linghong Sun Haoyang Xie Mingqi Zhao Long Zhou Hongxing Wu Haifeng Wang State Key Laboratory of Solidification Processing Center of Advanced Lubrication and Seal MaterialsNorthwestern Polytechnical UniversityXi’an 720072China

Fretting damage is common in the high-strength titanium alloy fastener widely used in the aeronautic industry,leading to the failure of fastening fit or the initiation of *** titanium alloy fasteners often have typical preferred orientation characteristics(i.e.,texture),and this is one of the important factors affecting its ***,the investigations on the mechanism ofβrolling-texture intensity on fretting damage resistance and subsurface deformation are less ***,fretting wear tests were carried out on samples with different rolling texture *** results demonstrate that the samples with quite low(A-10%sample)and quite high(D-70%sample)rolling-texture intensity both exhibit excellent fretting wear resistance,but their mechanisms are completely *** dispersed grain orientation renders the A-10%sample with good recovery ability and a positive friction effect during *** stress only concentrating at grain boundaries(GBs)weakens cracks’initiation and *** unique orientation-layered structure(OLS)leads to excellent recovery ability and a positive friction *** propagation is inhibited and only propagates along the OLS boundary without a connected ***,samples with moderate rolling texture intensity exhibit severe *** are restricted in local areas,so the poor recovery ability makes them have a negative friction *** propagation driving force continuously *** rolling texture intensity can reduce wear by three *** study can provide information on the principle for designing fretting damage-resistant alloys.

关键词： High-strength titanium alloy Rolling-texture intensity Fretting wear Subsurface deformation

来源：评论

学校读者我要写书评

暂无评论

Universal Encapsulation Adhesive for Lead Sedimentation and Attachable Perovskite Solar Cells with Enhanced Performance

引用

Energy & Environmental materials 2024年第3期7卷 303-310页

作者： Xuehao Zhu Haoyu Cai Cong Bai Zhengzhe Wu Wenjian Shen Yiming Xiong Juan Zhao Fuzhi Huang Yibing Cheng Jie Zhong Research Centre for Advanced Thin Film Photovoltaics State Key Laboratory of Advanced Technology for Materials Synthesis and ProcessingWuhan University of TechnologyWuhan 430070China Foshan Xianhu Laboratory of the Advanced Energy Science and Technology Guangdong Laboratory Foshan 528216China School of Automobile Engineering Wuhan University of TechnologyWuhan 430070China

In this work,a modified polyurethane adhesive(PUA)was prepared to realize a convenient encapsulation strategy for lead sedimentation and attachable perovskite solar cells(A-PSCs).The modified PUA can completely self-heal within 45 min at room temperature with an efficient lead ion-blocking rate of 99.3%.The PUA film can be coated on a metal electrode with slight efficiency improvement from 23.96%to 24.15%.The thermal stability at 65℃and the humidity stability at 55%relative humidity(RH)are superior to the devices encapsulated with *** PUA film has strong adhesion to the flexible substrate and the initial efficiency of the flexible perovskite module(17.2%)encapsulated by PUA remains 92.6%within 1825 *** results suggest that PUA encapsulation is universal for rigid and flexible PSCs with enhanced stability and low lead ***,it was found that flexible PSCs can be well attached to various substrates with PUA,providing a facile route for the A-PSCs in various scenarios without additional encapsulation and installation.

关键词： adhesive attachable device flexible module lead leakage polyurethane

来源：评论

学校读者我要写书评

暂无评论

Exploring the oxidation behaviors of the Ti-V-Cr-Mo high-entropy MAX at 800 ℃ for its self-lubricity

引用

Journal of materials Science & technology 2024年第20期187卷 49-62页

作者： Cheng-Feng Du Yaqing Xue Hongwei Liang Chuanchao Wang Qingyan Zeng Jinjin Wang Lili Xue Hong Yu State Key Laboratory of Solidification Processing Center of Advanced Lubrication and Seal MaterialsNorthwestern Polytechnical UniversityXi’an 710072China

Given the unique nanolaminate structure,the MAX phase ceramics which are composed of alternatively stacked two-dimensional(2D)metal(M)carbides(X)and main group(A)atomic layers have shown promising properties at elevated ***,an excellent self-lubricating performance of a high-entropy(HE)(TiVCrMo)_(3)AlC_(2)MAX is demonstrated at 800℃ in the ***,the formation mechanism of a self-lubricative tribofilm is still waiting for *** this work,the HE(TiVCrMo)_(3)AlC_(2)MAX is synthesized and its oxidation behaviors are systematically evaluated at 800℃ in the air.A two-stage parabolic oxidation behavior is detected,which can be mainly ascribed to the volatilization of MoO_(3)species coupled with the thickening of the compound oxide ***,the HE com-position results in chemically complex phases including Rutile and vacancy-ordered TiO species in the oxide scale,which contribute to a higher ion diffusion rate for mass ***,the continued volatilization of MoO_(3)is beneficial for the enhanced lubricity and anti-wear performance of the(TiVCrMo)_(3)AlC_(2)MAX at 800℃.

关键词： MAX High-entropy High-temperature oxidation Kinetics Oxide scale

来源：评论

学校读者我要写书评

暂无评论

Laser Powder Bed Fusion of Beta-Type Titanium Alloys for Biomedical Application:A Review

引用

Acta Metallurgica Sinica(English Letters) 2024年第1期37卷 17-28页

作者： Xuan Luo Chao Yang Dongdong Li Lai-Chang Zhang State Key Laboratory of Materials Processing and Die&Mould Technology Huazhong University of Science and TechnologyWuhan430074China National Engineering Research Center of Near-Net-Shape Forming for Metallic Materials Guangdong Provincial Key Laboratory for Processing and Forming of Advanced Metallic MaterialsSouth China University of TechnologyGuangzhou510640China Centre for Advanced Materials and Manufacturing School of EngineeringEdith Cowan University270 Joondalup DriveJoondalupPerthWA6027Australia

Additive manufacturing ofβ-type titanium alloy is expected to replace Ti-6Al-4V alloy in the field of orthopedic implantation because of their low elastic modulus,excellent corrosion resistance,and *** briefly introducing the laser powder bed fusion(LPBF)process and physical phenomena,this paper reviews the recent progresses in LPBF-edβ-type Ti *** strategies to strengthening and tougheningβ-type Ti alloys are critically *** is followed by the processing routes employed to achieve to low modulus for orthopedic applications,especially a new methodology for tailoring crystallographic orientation called multi-track coupled directional *** effect of processing and compositions on performance metrics ofβ-type Ti alloys included corrosion behavior,and biocompatibility is *** the end,challenges in additive manufacturing ofβ-type Ti alloys in future are highlighted,with the aim to ensue clinical application of LPBF-edβ-type Ti alloys.

关键词： β-type Ti alloys Laser powder bed fusion Mechanical properties Elastic modulus Biocompatibility

来源：评论

学校读者我要写书评

暂无评论

The deteriorated degradation resistance of Mg alloy microtubes for vascular stent under the coupling effect of radial compressive stress and dynamic medium

引用

Journal of Magnesium and Alloys 2024年第2期12卷 573-585页

作者： Mengyao Liu Yabo Zhang Qingyuan Zhang Yan Wang Di Mei Yufeng Sun Liguo Wang Shijie Zhu Shaokang Guan School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China Henan Key Laboratory of Advanced Magnesium Alloys Zhengzhou 450002China Key Laboratory of Advanced Materials Processing&Mold Ministry of Education Zhengzhou 450002China

The degradation of Mg alloys relates to the service performance of Mg alloy biodegradable *** order to investigate the degradation behavior of Mg alloys as vascular stent materials in the near service environment,the hot-extruded fine-grained Mg-Zn-Y-Nd alloy microtubes,which are employed to manufacture vascular stents,were tested under radial compressive stress in the dynamic Hanks'Balanced Salt Solution(HBSS).The results revealed that the high flow rate accelerates the degradation of Mg alloy microtubes and its degradation is sensitive to radial compressive *** results contribute to understanding the service performance of Mg alloys as vascular stent materials.

关键词： Mg alloy Microtubes Degradation behavior Radial compressive stress Dynamic conditions

来源：评论

学校读者我要写书评

暂无评论

300 MPa grade biodegradable high-strength ductile low-alloy(BHSDLA)Zn-Mn-Mg alloys:An in vitro study

引用

Journal of materials Science & technology 2023年第7期138卷 233-244页

作者： Zhang-Zhi Shi Xiang-Min Li Sheng-Lian Yao Yun-Zhi Tang Xiao-Jing Ji Qiang Wang Xi-Xian Gao Lu-Ning Wang Beijing Advanced Innovation Center for Materials Genome Engineering Key Laboratory for Advanced Materials Processing of Ministry of EducationSchool of Materials Science and EngineeringUniversity of Science and Technology BeijingBeijing 100083China

300 MPa grade biodegradable Zn-(0.6,0.8)Mn-(300 MPa and elongations>15%have been developed,which are designated as Zn06Mn006Mg(HE)and Zn08Mn005Mg(HE)in as-extruded *** are the newest members of a small group of bio... 详细信息

300 MPa grade biodegradable Zn-(0.6,0.8)Mn-(<0.1)Mg alloys with yield strengths>300 MPa and elongations>15%have been developed,which are designated as Zn06Mn006Mg(HE)and Zn08Mn005Mg(HE)in as-extruded *** are the newest members of a small group of biodegradable Zn alloys with mechanical properties beyond the generally accepted benchmark for orthopedic *** in simulated body fluid for 30 days,Zn06Mn006Mg(HE)and Zn08Mn005Mg(HE)exhibit corrosion rates of 38 and 53μm y^(-1),*** show high antibacterial rates of 93%-97%against *** 25%-75%extracts of both the alloys,MC3T3-E1 cell viabilities for 1 day and 3 days are all over 100%,indicating complete *** 100%extracts for 3 days,both alloys show *** a longtime room temperature storage of 72 weeks,natural embrittling alike Zn-Mg alloys does not *** Zn-Mn-Mg alloys still have mechanical properties exceeding the benchmark by a large *** in vitro study shows the newly developed BHSDLA Zn-Mn-Mg alloys are promising candidates for orthopedic implants.

关键词： Biodegradable Zn alloys Orthopedic implants Microstructure Mechanical properties Biocompatibility

来源：评论

学校读者我要写书评

暂无评论

Generation and Suppression of Pendant Droplet Oscillation in Electron Beam Directed Energy Deposition

引用

Engineering 2024年第6期37卷 215-229页

作者： Zhiyue Liang Zhenyu Liao Haoyu Zhang Zixiang Li Li Wang Baohua Chang Dong Du Department of Mechanical Engineering Tsinghua UniversityBeijing 100084China Key Laboratory for Advanced Materials Processing Technology Ministry of EducationTsinghua UniversityBeijing 100084China

Electron beam–directed energy deposition(EB–DED)has emerged as a promising wire-based metal additive manufacturing ***,the effects of EBs on pendant droplets at wire tips have not yet been *** aim of this study is to enhance the understanding of this action by analyzing the mechanism of droplet *** pendant droplet oscillation phenomenon hinders the stable transfer of droplets to the molten pool and limits the feasibility of manufacturing complex lattice structures by EB–***,another aim of this study is to create an oscillation suppression *** escalating asymmetric amplitude is the main characteristic of droplet *** primary oscillationinducing force is the recoil force generated from the EB-acted local surface of the *** physical mechanism of this force is the rapid increase and uneven distribution of the local surface temperature caused by the partial action of the *** prerequisites for droplet oscillation include vacuum conditions,high power densities,and bypass wire feeding *** proposed EB–dynamic surrounding melting(DSM)method can be applied to conveniently and effectively suppress oscillations,enable the accurate transfer of droplets to the molten pool,and achieve stable processes for preparing the strut elements of lattice *** the temperature and improving the uniformity of its distribution are the mechanisms of oscillation suppression in EB–*** this study,the physical basis for interpreting the mechanism by which EBs act on droplets and the technical basis for using EB–DED to prepare complex lattice structure parts are provided.

关键词： Additive manufacturing Electron beam freeform fabrication In situ monitoring Pendant droplet

来源：评论

学校读者我要写书评

暂无评论

1,3,5-Trifluorobenzene endorsed EC-free electrolyte for high-voltage and wide-temperature lithium-ion batteries

引用

Journal of Energy Chemistry 2023年第10期85卷 49-57,I0003页

作者： Mingsheng Qin Ziqi Zeng Qiang Wu Xiaowei Liu Qijun Liu Shijie Cheng Jia Xie State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic EngineeringHuazhong University of Science and TechnologyWuhan 430074HubeiChina State Key Laboratory of Materials Processing and Die&Mould Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074HubeiChina State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070HubeiChina

Ethylene carbonate(EC)is susceptible to the aggressive chemistry of nickel-rich cathodes,making it undesirable for high-voltage lithium-ion batteries(LIBs).The arbitrary elimination of EC leads to better oxidative tolerance but always incurs interfacial degradation and electrolyte ***,an EC-free electrolyte is deliberately developed based on gradient solvation by pairing solvation-protection agent(1,3,5-trifluorobenzene,F_(3)B)with propylene carbonate(PC)/methyl ethyl carbonate(EMC)formulation.F_(3)B keeps out of inner coordination shell but decomposes preferentially to construct robust interphase,inhibiting solvent decomposition and electrode ***,the optimized electrolyte(1.1 M)with wide liquid range(-70–77℃)conveys decent interfacial compatibility and high-voltage stability(4.6 V for LiNi_(0.6)Mn_(0.2)Co_(0.2)O_(2),NCM622),qualifying reliable operation of practical NCM/graphite pouch cell(81.1%capacity retention over 600 cycles at 0.5 C).The solvation preservation and interface protection from F_(3)B blaze a new avenue for developing high-voltage electrolytes in next-generation LIBs.

关键词： Lithium-ion batteries Solvation structure High-voltage electrolyte Wide-temperature range Interfacial chemistry

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：