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6th International Conference on intelligent computing and Signal Processing (ICSP)

作者： Xiaohua Wang Jie Yang Min Hu Xia Wu Anhui Province Key Laboratory of Affective Computing and Advanced Intelligent Machine School of Computer Science and Information Engineering Hefei University of Technology Hefei China

Traditional image emotion recognition focuses only on the emotion information embedded in the subject or part of the image, while ignoring the global emotion information. In this paper, we propose a new network based on Vision Transformer: a global perception network, containing a main module and a background module. The main module enhances the weighting of objects by showing the interdependencies between modelled channels. The background module further searches for emotional information in the background. In addition, we employ multi-task learning and Adaptive Gradient Clipping to improve the network. Extensive experiments show that our proposed method outperforms the state-of-the-art methods for image sentiment analysis.

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Deep Reinforcement Learning with Human Guidance for Autonomous Driving Car Following

Deep Reinforcement Learning with Human Guidance for Autonomo...

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IEEE International Conference on Mechatronics, Robotics and Automation (ICMRA)

作者： Wenbo Wang Qingchao Xu Xingfu Yang Yandong Liu School of Software Engineering Dalian University Dalian China Key Laboratory of Advanced Design and Intelligent Computing Ministry of Education Dalian University Dalian China

ISBN: (数字)9798350307535

ISBN: (纸本)9798350307542

To solve the complex modeling and difficult parameter adjustment of traditional car-following control methods, we propose the car-following framework KgPPO-CF. The KgPPOCF brings expert experience into the interactive process of Deep Reinforcement Learning, which improves the speed and robustness of training policies. We use four different reward functions and compare the effects of policies trained by different designs on car-following control. In the Carla simulator, KgPPO-CF achieves car-following control in a continuous action space. The experimental results show that, compared with the traditional control methods, the control strategy obtained by KgPPO-CF training has better adaptability.

关键词： Training Accuracy Mechatronics Aerospace electronics Deep reinforcement learning Robustness Automobiles Robotics and automation Standards Autonomous vehicles

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Identification of key Genes as Potential Drug Targets for Gastric Cancer

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Tsinghua Science and Technology 2023年第4期28卷 649-664页

作者： Md.Tofazzal Hossain Md.Selim Reza Yin Peng Shengzhong Feng Yanjie Wei Center for High Performance Computing Joint Engineering Research Center for Health Big Data Intelligent Analysis TechnologyShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China School of Computer Science and Technology University of Chinese Academy of SciencesBeijing 100049China Department of Statistics Bangabandhu Sheikh Mujibur Rahman Science and Technology UniversityGopalganj 8100Bangladesh Guangdong Provincial Key Laboratory for Genome Stability and Disease Prevention and Regional Immunity and Diseases Department of PathologyShenzhen UniversityShenzhen 518060China

Gastric cancer(GC)is one of the most common cancers and ranks the third in cancer mortality all over the *** goal of this study was to identify potential hub-genes,highlighting their functions,signaling pathways,and candidate drugs for the treatment of GC *** used publicly available next generation sequencing(NGS)data to identify differentially expressed(DE)*** top DE genes were mapped to STRING database to construct the protein-protein interaction(PPI)network and top hub genes were selected for further *** found a total of 1555 DE genes with 870 upregulated and 685 downregulated genes in *** selected the top 400(200 upregulated and 200 downregulated)genes to construct a PPI network and extracted the top 15 hub *** gene ontology(GO)term and kyoto encyclopedia of genes and genomes(KEGG)pathway enrichment analyses of the 15 hub genes exposed some important functions and signaling pathways that were significantly associated with GC *** survival analysis of the hub genes disclosed that the lower expressions of the three hub genes CDH2,COL4A1,and COL5A2 were associated with better survival of GC *** three genes might be the candidate biomarkers for the diagnosis and treatment of ***,we considered 3 key proteins(genomic biomarkers)(COL4A1,CDH2,and CO5A2)as the drug target proteins(receptors),performed their docking analysis with the 102 meta-drug agents,and found Everolimus,Docetaxel,Lanreotide,Venetoclax,Temsirolimus,and Nilotinib as the top ranked 6 candidate drugs with respect to our proposed target proteins for the treatment against GC ***,the proposed drugs might play vital role for the treatment against GC patients.

关键词： gastric cancer hub genes candidate genes molecular docking candidate drugs

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OSRE: Object-to-Spot Rotation Estimation for Bike Parking Assessment

arXiv

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arXiv 2023年

作者： Alfasly, Saghir Al-Huda, Zaid Bello, Saifullah Elazab, Ahmed Lu, Jian Xu, Chen Shenzhen Key Laboratory of Advanced Machine Learning and Applications Shenzhen University China Guangdong Key Laboratory of Intelligent Information Processing China School of Computing and Artificial Intelligent Southwest Jiaotong University China School of Biomedical Engineering Shenzhen University China

Current deep models provide remarkable object detection in terms of object classification and localization. However, estimating object rotation with respect to other visual objects in the visual context of an input image still lacks deep studies due to the unavailability of object datasets with rotation annotations. This paper tackles these two challenges to solve the rotation estimation of a parked bike with respect to its parking area. First, we leverage the power of 3D graphics to build a camera-agnostic well-annotated Synthetic Bike Rotation Dataset (SynthBRSet). Then, we propose an object-to-spot rotation estimator (OSRE) by extending the object detection task to further regress the bike rotations in two axes. Since our model is purely trained on synthetic data, we adopt image smoothing techniques when deploying it on real-world images. The proposed OSRE is evaluated on synthetic and real-world data providing promising results. Our data and code are available at https://***/OSRE/. © 2023, CC BY.

关键词： Rotation

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MFN: Explainable DNA triple helixes Stabilized Design based on mCGR and flow network

MFN: Explainable DNA triple helixes Stabilized Design based ...

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IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

作者： Xiaoru Wen Lijun Sun Lei Xie Yanfen Zheng Ben Cao Bin Wang Key Laboratory of Advanced Design and Intelligent Computing Ministry of Education School of Software Engineering Dalian University Dalian China School of Computer Science and Technology Dalian University of Technology Dalian China

ISBN: (数字)9798350386226

ISBN: (纸本)9798350386233

DNA triple helix structure, as a highly specific gene targeting tool, enable gene regulation by precisely identifying and binding to target DNA sequences. However, the limits of design quality and efficiency affect their wide application in gene therapy. Therefore, in this paper, we propose an antiparallel DNA triple helixes design method-MFN based on matrix chaotic game representation (mCGR) and flow network. Leveraging the structural characteristics of DNA sequences, this method employs the mCGR algorithm to construct an initial matrix, generating a set of DNA sequences that conform to foundational constraints. Then, these sequences are mapped as stream network nodes to screen crosstalk structures by path search, and the whole process is observable and interpretable. Experimental results show that MFN significantly improves the design efficiency of triple helix structure and reduces crosstalk phenomenon. Wet experiments further verify the effectiveness of the method. In summary, MFN achieves an efficient and high-quality design of DNA triple helixes and provides a new idea for targeted gene therapy.

关键词： Scalability Design methodology DNA Crosstalk Genomics Games Reliability engineering Regulation Gene therapy Bioinformatics

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Remolding Semantic Focus with Dual Attention Mechanism for Aspect-based Sentiment Analysis 8

Remolding Semantic Focus with Dual Attention Mechanism for A...

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8th IEEE International Conference on Cloud computing and Intelligence Systems, CCIS 2022

作者： Li, Xingda Bao, Yanwei Hu, Min Ren, Fuji Hefei University of Technology Hefei Anhui230009 China Hefei University of Technology Anhui Province Key Laboratory of Affective Computing and Advanced Intelligent Machine China University of Electronic Science and Technology of China Chengdu Chengdu611730 China

ISBN: (纸本)9781665477352

Aspect-based sentiment analysis (ABSA) is an NLP task that classify fine-grained sentiment towards one specific aspect from the same text. While attention mechanism has achieved great success, attaching aspects to abstract sentiment remains challenging. In this paper, we propose dual attention mechanism, a novel method to re-weight the distribution of attention between stack BERT layers, in prompt learning way with pretrained language model BERT. Specifically, after obtaining the most attractive words, the method raises weight of other possible corresponding words and makes model consider more comprehensively. To introduce more aspect information, we classify the sentiment in improved prompt learning way. Note that the overfitting using BERT on ABSA, we utilize the approach of staged loss that restrict the training not too small. Finally, the experiment results demonstrate the effectiveness and the stability of dual attention and provide a good insight of attention mechanism. © 2022 IEEE.

关键词： Sentiment analysis

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CLIMS++: Cross Language Image Matching with Automatic Context Discovery for Weakly Supervised Semantic Segmentation

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International Journal of Computer Vision 2025年 1-20页

作者： Xie, Jinheng Deng, Songhe Hou, Xianxu Luo, Zhaochuan Shen, Linlin Huang, Yawen Zheng, Yefeng Shou, Mike Zheng Computer Vision Institute School of Computer Science and Software Engineering Shenzhen University Shenzhen518060 China Department of Computer Science Wenzhou-Kean University Wenzhou325060 China Guangdong Provincial Key Laboratory of Intelligent Information Processing Shenzhen University Shenzhen China Show Lab National University of Singapore Singapore639798 Singapore School of AI and Advanced Computing Xi’an Jiaotong-Liverpool University Suzhou215400 China Jarvis Research Center Tencent YouTu Lab Shenzhen518703 China

While promising results have been achieved in weakly-supervised semantic segmentation (WSSS), limited supervision from image-level tags inevitably induces discriminative reliance and spurious relations between target classes and background regions. Thus, Class Activation Map (CAM) usually tends to activate discriminative object regions and falsely includes lots of class-related backgrounds. Without pixel-level supervisions, it could be very difficult to enlarge the foreground activation and suppress those false activation of background regions. In this paper, we propose a novel framework of Cross Language Image Matching with Automatic Context Discovery (CLIMS++), based on the recently introduced Contrastive Language-Image Pre-training (CLIP) model, for WSSS. The core idea of our framework is to introduce natural language supervision to activate more complete object regions and suppress class-related background regions in CAM. In particular, we design object, background region, and text label matching losses to guide the model to excite more reasonable object regions of each category. In addition, we propose to automatically find spurious relations between foreground categories and backgrounds, through which a background suppression loss is designed to suppress the activation of class-related backgrounds. The above designs enable the proposed CLIMS++ to generate a more complete and compact activation map for the target objects. Extensive experiments on PASCAL VOC 2012 and MS COCO 2014 datasets show that our CLIMS++ significantly outperforms the previous state-of-the-art methods. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025.

关键词： Semantic Segmentation

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Performance Verification of Smith Predictor Control Using IMC Scheme via Chemical Reaction Networks and DNA Strand Displacement Reaction

Performance Verification of Smith Predictor Control Using IM...

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Smart World Congress (SWC), IEEE

作者： Jingwang Yao Hui Lv Yijun Xiao Key Laboratory of Advanced Design and Intelligent Computing Ministry of Education School of Software Engineering Dalian University Dalian China State Key Laboratory of Synthetical Automation for Process Industries Northeastern University Shenyang China

Biochemical process control is often achieved through feedback control strategies for theoretical analysis and optimization of biochemical reaction processes. Here, the design improves the robustness of the biochemical process by taking advantage of the Smith prediction structure and internal mode control within the chemical reaction network theory framework to intervene against the time delays and perturbations present in the biochemical process. First, an IMC representation of Smith prediction is constructed using the presence of parameter rectification of the control method, and then an IMC-MSP control scheme is proposed. A first-order time-lag controlled object is established in the construction of the IMC-MSP control scheme. Besides, CRNs and kinetic representations are established based on the control structure to facilitate the evaluation of the control system performance. In this paper, CRNs representations of parabolic functions as signal inputs are defined for the first time and optimized for stepping signals to facilitate the design and study of biomolecular circuits. Notably, for the CRNs-based IMC-MSP control scheme, on the one hand, numerical simulation experiments are designed to verify the effectiveness of the whole scheme from multiple perspectives of time delays, external perturbations, and filter tuning parameters; on the other hand, using DNA strand displacement is reflected to verify the feasibility of the whole scheme.

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Rsta: A Reversible Signal Transmission Architecture for Breaking the Limitation of Unidirectional Transmission

SSRN

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SSRN 2025年

作者： Liu, Xin Cui, Shuang Zhang, Xun Zhou, Fuxing Sheng, Kaikai Wang, Bin Zhang, Qiang School of Computer Science and Technology Dalian University of Technology Dalian116024 China Key Laboratory of Advanced Design and Intelligent Computing Ministry of Education School of Software Engineering Dalian University Dalian116622 China

Molecular circuits are essential tools for biosensing and molecular information processing. However, the long-distance and reversible transmission of orthogonal signals remains a significant challenge in molecular circuits, preventing molecular signals from achieving reversible transmission similar to that of electrical signals in wires. To overcome the limitations of unidirectional signal transmission and facilitate the integration of antagonistic circuits. We propose a reversible signal transmission architecture (RSTA) with wire-like characteristics to achieve reversible signal transmission based on fundamental molecular devices known as reversible signal fan-out devices (RSFDs). The polarity of the input signal dictates the transmission direction, establishing the initial condition for the output signals. Cascaded RSFDs within RSTA offer two key advantages. First, the temporal response to signals. Second, the reversible transformation of opposite circuit types without structural modification. We experimentally validated the principles and functionality of RSTA using temporal logic device and integrated molecular circuits. This work advances the field of reversible molecular signal transmission, enabling the rational design of complex molecular circuits and molecular information processing systems. We envision applications of this technology in nanomachines, molecular computing, and biosensing. © 2025, The Authors. All rights reserved.

关键词： Temporal logic

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A Novel Deep Learning Approach Featuring Graph-Based Algorithm for Cell Segmentation and Tracking

A Novel Deep Learning Approach Featuring Graph-Based Algorit...

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2023 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2023

作者： Zhao, Keliang Niyogisubizo, Jovial Xiao, Linxia Pan, Yi Wei, Dongqing Rosiyadi, Didi Wei, Yanjie Chinese Academy of Sciences Shenzhen Key Laboratory of Intelligent Bioinformatics and Center for High Performance Computing Shenzhen Institute of Advanced Technology Shenzhen518055 China Chinese Academy of Sciences College of Computer Science and Control Engineering Shenzhen Institutes of Advanced Technology Shenzhen518055 China Shanghai Jiao Tong University State Key Laboratory of Microbial Metabolism School of Life Sciences and Biotechnology Shanghai200240 China National Research and Innovation Agency Research Center for Artificial Intelligence and Cybersecurity Bandung Indonesia

ISBN: (纸本)9798350337488

The precise segmentation and tracking of cells in microscopy image sequences play a pivotal role in biomedical research, facilitating the study of tissue, organ, and organism development. However, manual segmentation and tracking of cells is time-consuming and often require professional experiences. Besides, segmenting cells in the images with a low signal-to-noise ratio remains difficult. While deep learning (DL) has become a common method for cell segmentation, few DL- based methods address concurrent cell segmentation and tracking. In this paper, we propose a novel DL approach featuring graph-based tracking for cell segmentation and tracking in microscopy images. We combine Deeplabv3+ for semantic segmentation and ResNet50 for enhanced feature extraction, enabling comprehensive cell detection and instance segmentation. Post-processing, involving non-maxima suppression and outlier detection, refines predictions and produces final segmentation. The tracking method is based on the relative position of graph nodes to track segmented cells, encompassing cell division and apoptosis. We conduct our experiments on the induced pluripotent stem (iPS) cell datasets, and the results show that the segmentation and tracking performance of our method yields superior performance compared to the benchmark models. More specifically, our approach achieved DET values of 0.955 and 0.913, TRA values of 0.951 and 0.906, and SEG values of 0.690 and 0.665 on two iPS dataset videos, respectively. Additionally, the performance assessment encompasses four real microscopy datasets from the Cell Tracking Challenge (CTC). Our method greatly reduces the cost of manual labeling and labor-intensive costs. © 2023 IEEE.

关键词： cell segmentation cell tracking deep learning Deeplabv3+ instance segmentation iPS cell reprogramming

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