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International Conference on Acoustics, Speech, and Signal Processing (ICASSP)

作者： Jindong Xie Jiachen Liu Yupei Lin Jinbao Wang Xianxu Hou Linlin Shen Computer Vision Institute School of Computer Science and Software Engineering Shenzhen University National Engineering Laboratory for Big Data System Computing Technology Shenzhen University School of Information Engineering Guangdong University of Technology Guangzhou China Guangdong Provincial Key Laboratory of Intelligent Information Processing School of AI and Advanced Computing Xi’an Jiaotong-Liverpool University

ISBN: (数字)9798350368741

ISBN: (纸本)9798350368758

The 3D generative adversarial network (GAN) inversion converts an image into 3D representation to attain high-fidelity reconstruction and facilitate realistic image manipulation within the 3D latent space. However, previous approaches face challenges regarding the trade-off between the reconstruction ability and editability. That is, reversing a real-world image to a low-dimensional latent code would inevitably lead to information loss, and achieving a near-perfect reconstruction using high-rate triplane representation often limits the ability to manipulate the image freely in the latent space. To address these issues, we propose a novel latent conditioning encoder-based framework with the alignment between the low-dimensional latent and high-dimensional triplane. A non-semantic guided editing strategy bridges the intrinsic relation between the latent condition and triplane generation, making it possible to edit the high-dimensional representation by latent manipulation. As a result, our method can achieve high-fidelity reconstruction and editing simultaneously by directly controlling the latent code. Experimental results demonstrate that our approach excels in reconstruction and editing quality compared to previous 3D inversion methods. Furthermore, our method can also edit even real faces with large poses and out-of-domain cases.

关键词： Bridges Three-dimensional displays Codes Signal processing Generative adversarial networks Vectors Acoustics Speech processing Image reconstruction Faces

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Single-cell technologies: current and near future

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Science China(Life Sciences) 2025年第1期68卷 1-4页

作者： Chenfei Wang Qi Liu Xiaohui Fan Tieliu Shi KeyLaboratory of Spine and Spinal CordInjury Repairand Regeneration Ministry of EducationOrthopedics DepartmentTongji HospitalBioinformatics DepartmentSchoolofLifeSciencesandTechnologyTongji UniversityShanghai 200082China Frontier Science Center for Stem Cells School of Life Sciences and TechnologyTongji UniversityShanghai 200092China Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji UniversityShanghai 200082China Research Institute of Intelligent Computing Zhejiang LabHangzhou 311121China Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang UniversityJiaxing 314103China Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal UniversityShanghai 200241China Key Laboratory of Advanced Theory and Application in Statistics and Data Science(MOE) School of StatisticsEast China Normal UniversityShanghai 200062China

Single-cell technologies enable the indepth exploration of multiple biological hierarchies at the scale of individual cells,which have deepened our knowledge of cellular diversity,tissue organization,and overall organism function(Sun et al.,2024).In 2009,single-cell RNA sequencing(scRNA-seq)was first developed as a powerful tool to dissect gene expression and uncover transcriptional *** the rapid advancement of technology,single-cell approaches have expanded to encompass other omics,such as genomics,epigenomics,proteomics,and ***,multimodal technologies including spatially resolved transcriptomics and clustered regularly interspaced short palindromic repeats(CRISPR)screening at the single-cell level further advanced our ability to comprehensively understand cellular ***-cell methods provide deeper insights into disease mechanisms across various conditions,including cancer,developmental disorders,and aging-associated *** this issue,we focus on topics related to single-cell methods,covering the following four aspects:(i)single-cell multi-omic sequencing technology;(ii)single-cell spatial technology;(iii)singlecell CRISPR screening technology;(iv)applications of single-cell technology.

关键词： expanded enable insight

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Family of Mutually Uncorrelated Codes for DNA Storage Address Design

IEEE Transactions on Nanobioscience

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IEEE Transactions on Nanobioscience 2025年 PP卷 PP页

作者： Liu, Zhenlu Cao, Ben Shao, Qi Zheng, Yanfen Wang, Bin Zhou, Shihua Zheng, Pan Dalian University Key Laboratory of Advanced Design and Intelligent Computing Ministry of Education School of Software Engineering Dalian116622 China Dalian University of Technology School of Computer Science and Technology Dalian116024 China University of Canterbury Upper Riccarton Department of Accounting and Information Systems Christchurch8140 New Zealand

Deoxyribonucleic acid (DNA) has become an ideal medium for long-term storage and retrieval due to its extremely high storage density and long-term stability. But access efficiency is an existing bottleneck in DNA storage, especially the lack of high-quality random access address sequences. Therefore, in this paper, we report a series of approaches based on k-weakly mutually uncorrelated (k-WMU) codes to design the address sequence to improve the access efficiency of DNA storage. To address the problem of DNA sequences that are poorly scalable at the base level, we propose a 0-m-ruling coding scheme combined with k-WMU codes that can make address sequences avoid generating secondary structure with stem lengths ranging from 3 to 9. Based on the decoupled structure, We further extend the k-WMU codes with error correction function while satisfying combinatorial biological constraints. In order to investigate the performance of the designed address sequences for real-world applications, we perform simulation experiments based on thermodynamic properties and error correction capability as well as compared the minimum free energy (MFE), melting temperature (TM), and average decoding success rate (ADSR) with previous work. The results show that designed address sequences have a high MFE value and ADSR and a substantial reduction in TM-variance while satisfying the combinatorial biological constraints. As the quality of address sequences improves, this will help to achieve accurate random access as well as enhance the robustness of the DNA storage system. © 2002-2011 IEEE.

关键词： DNA sequences

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NavG: Risk-Aware Navigation in Crowded Environments Based on Reinforcement Learning with Guidance Points

arXiv

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arXiv 2025年

作者： Zhang, Qianyi Luo, Wentao Liu, Boyi Zhang, Ziyang Wang, Yaoyuan Liu, Jingtai Institute of Robotics and Automatic Information System Nankai University Tianjin Key Laboratory of Intelligent Robotics Tianjin China Advanced Computing and Storage Lab Huawei 2012 Lab China Department of Electronic and Computer Engineering The Kong Kong University of Science and Technology Hong Kong

Motion planning in navigation systems is highly susceptible to upstream perceptual errors, particularly in human detection and tracking. To mitigate this issue, the concept of guidance points—a novel directional cue within a reinforcement learning-based framework—is introduced. A structured method for identifying guidance points is developed, consisting of obstacle boundary extraction, potential guidance point detection, and redundancy elimination. To integrate guidance points into the navigation pipeline, a perception-to-planning mapping strategy is proposed, unifying guidance points with other perceptual inputs and enabling the RL agent to effectively leverage the complementary relationships among raw laser data, human detection and tracking, and guidance points. Qualitative and quantitative simulations demonstrate that the proposed approach achieves the highest success rate and near-optimal travel times, greatly improving both safety and efficiency. Furthermore, real-world experiments in dynamic corridors and lobbies validate the robot’s ability to confidently navigate around obstacles and robustly avoid pedestrians. © 2025, CC BY.

关键词： Travel time

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A Bi-selection Method Based on Consistent Matrix for Large-Scale Datasets

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IEEE Transactions on Fuzzy Systems 2025年

作者： Quan, Jinsheng Qiao, Fengcai Yang, Tian Shen, Shuo Qian, Yuhua Hunan Normal University Hunan Provincial Key Laboratory of Intelligent Computing and Language Information Processing Institute of Interdisciplinary Studies Changsha410081 China National University of Defense Technology College of Advanced Interdisciplinary Studies Changsha410081 China Shanxi University Institute of Big Data Science and Industry Taiyuan030006 China

Biselection (feature and sample selection) enhances the efficiency and accuracy of machine learning models when handling large-scale data. Fuzzy rough sets, an uncertainty mathematics model known for its excellent interpretability, are widely used in machine learning, particularly for feature selection. While the consistent matrix has significantly improved the computational efficiency and scalability of feature selection, like most fuzzy rough set-based methods, it focuses only on feature selection and seldom incorporates sample selection. This feature-centric approach can limit classification performance, particularly in noisy and large-scale datasets where both features and samples require judicious selection. To overcome these limitations, this article explores the integration of sample selection with feature selection. First, we introduce a β-consistent granulation method to generate more accurate and concise fuzzy information granules, reducing the impact of noisy samples. In addition, a novel membership function is employed to distinguish noise while simultaneously evaluating both features and samples. As a result, a biselection algorithm with linear computation complexity is proposed to select high-quality features and samples. Numerical experiments demonstrate that, compared to eleven representative algorithms, our proposed method achieves an average accuracy improvement of 9.66% and a 933-fold increase in efficiency. © 2025 IEEE.

关键词： Biselection consistent matrix (CM) fuzzy sets granular computing rough sets

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A novel ECT image reconstruction method based on the deblurring diffusion model

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Flow Measurement and Instrumentation 2025年 104卷

作者： Liu, Yan-Dong Wu, Xin-Jie Liu, Shi-Xing Wang, Yi-Fan Key Laboratory of Advanced Design and Intelligent Computing Ministry of Education Dalian University Liaoning Dalian116622 China School of Software Engineering Dalian University Liaoning Dalian116622 China College of Physics Liaoning University Liaoning Shenyang110036 China School of Information Science and Engineering Shenyang University of Technology Liaoning Shenyang110870 China

To address the challenge of low reconstruction accuracy in Electrical Capacitance Tomography (ECT) images, we propose an imaging method based on a deblurring diffusion model, transforming the image reconstruction into image generation. In cases where the noise type affecting the ECT image reconstruction cannot be determined, inspired by the cold diffusion model, we use an alpha kernel instead of Gaussian noise to perform the image blurring process. During the deblurring process, we utilize the U-Net as the backbone network and incorporated the Linear Attention module to improve imaging accuracy. Additionally, recognizing the similarity between image error metrics and the Dice function, we integrate the Dice function into the loss. Simulation experiments demonstrate that the image errors and correlation coefficients using the proposed method outperform those achieved with the LBP, Tikhonov, Landweber, and classic CNNs. Finally, we deploy the proposed algorithm to the actual ECT system. © 2025 Elsevier Ltd

关键词： Image denoising

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Hi-End-MAE: Hierarchical encoder-driven masked autoencoders are stronger vision learners for medical image segmentation

arXiv

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arXiv 2025年

作者： Tang, Fenghe Yao, Qingsong Ma, Wenxin Wu, Chenxu Jiang, Zihang Zhou, S. Kevin Anhui Hefei230026 China Suzhou Institute for Advanced Research USTC Suzhou215123 China Stanford University Palo AltoCA94305 United States State Key Laboratory of Precision and Intelligent Chemistry USTC Anhui Hefei230026 China Institute of Computing Technology CAS Beijing100190 China

Medical image segmentation remains a formidable challenge due to the label scarcity. Pre-training Vision Transformer (ViT) through masked image modeling (MIM) on large-scale unlabeled medical datasets presents a promising solution, providing both computational efficiency and model generalization for various downstream tasks. However, current ViT-based MIM pre-training frameworks predominantly emphasize local aggregation representations in output layers and fail to exploit the rich representations across different ViT layers that better capture fine-grained semantic information needed for more precise medical downstream tasks. To fill the above gap, we hereby present Hierarchical Encoder-driven MAE (Hi-End-MAE), a simple yet effective ViT-based pre-training solution, which centers on two key innovations: (1) Encoder-driven reconstruction, which encourages the encoder to learn more informative features to guide the reconstruction of masked patches;and (2) Hierarchical dense decoding, which implements a hierarchical decoding structure to capture rich representations across different layers. We pre-train Hi-End-MAE on a large-scale dataset of 10K CT scans and evaluated its performance across seven public medical image segmentation benchmarks. Extensive experiments demonstrate that Hi-End-MAE achieves superior transfer learning capabilities across various downstream tasks, revealing the potential of ViT in medical imaging applications. The code is available at: https://***/FengheTan9/Hi-End-MAE. Copyright © 2025, The Authors. All rights reserved.

关键词： Computerized tomography

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COph100: A comprehensive fundus image registration dataset from infants constituting the "RIDIRP" database

arXiv

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arXiv 2025年

作者： Hu, Yan Gong, Mingdao Qiu, Zhongxi Liu, Jiabao Shen, Hongli Yuan, Mingzhen Zhang, Xiaoqing Li, Heng Lu, Hai Liu, Jiang Research Institute of Trustworthy Autonomous Systems Department of Computer Science and Engineering Southern University of Science and Technology Shenzhen China Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing Ophthalmology and Visual Sciences Key Laboratory Beijing China Center for High Performance Computing and Shenzhen Key Laboratory of Intelligent Bioinformatics Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen China

Retinal image registration is vital for diagnostic therapeutic applications within the field of ophthalmology. Existing public datasets, focusing on adult retinal pathologies with high-quality images, have limited number of image pairs and neglect clinical challenges. To address this gap, we introduce COph100, a novel and challenging dataset known as the Comprehensive Ophthalmology Retinal Image Registration dataset for infants with a wide range of image quality issues constituting the public "RIDIRP" database1. COph100 consists of 100 eyes, each with 2 to 9 examination sessions, amounting to a total of 491 image pairs carefully selected from the publicly available dataset. We manually labeled the corresponding ground truth image points and provided automatic vessel segmentation masks for each image. We have assessed COph100 in terms of image quality and registration outcomes using state-of-the-art algorithms. This resource enables a robust comparison of retinal registration methodologies and aids in the analysis of disease progression in infants, thereby deepening our understanding of pediatric ophthalmic conditions. Copyright © 2025, The Authors. All rights reserved.

关键词： Image registration

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Safe Reinforcement Learning for Social Motor Coordination in Two Dimensional Space

Safe Reinforcement Learning for Social Motor Coordination in...

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IEEE International Conference on Industrial Technology (ICIT)

作者： Fan Yang Yuening Huang Chao Zhai Hehong Zhang China University of Geosciences Wuhan Campus School of Automation Hubei Key Laboratory of Advanced Control and Intelligent Automation for Complex Systems Engineering Research Center of Intelligent Technology for Geo-Exploration Ministry of Education Wuhan China Rice University George R. Brown School of Engineering and Computing Houston Texas United States Fuzhou University School of Computer and Data Science Fuzhou China

ISBN: (数字)9798331521950

ISBN: (纸本)9798331521967

This paper presents an interactive motion control method based on reinforcement learning, designed to assist children with autism who have social motor impairments through a mirror game intervention. The virtual teacher uses the Deep Deterministic Policy Gradient (DDPG) algorithm to optimize its actions, guiding the participant to follow a Lissajous trajectory. To ensure safety, a motion-correction mechanism was developed, which automatically adjusts actions when the predicted trajectory surpasses predefined safety boundaries. The reward function considers both the distance between the virtual teacher and the target trajectory, as well as the distance between the virtual teacher and the participant, with dynamic adjustments applied by the motion-correction mechanism. Experimental results demonstrate that the virtual teacher effectively guides the participant towards the target trajectory while adhering to safety constraints.

关键词： Autism Filters Reinforcement learning Games Variable speed drives Motors Trajectory Safety Mirrors Motion control

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3D Anatomical Structure-Guided Deep Learning for Accurate Diffusion Microstructure Imaging

3D Anatomical Structure-Guided Deep Learning for Accurate Di...

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IEEE International Symposium on Biomedical Imaging

作者： Xinrui Ma Jian Cheng Wenxin Fan Ruoyou Wu Yongquan Ye Shanshan Wang Paul C. Lauterbur Research Center for Biomedical Imaging Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen Guangdong China University of Chinese Academy of Sciences Beijing China State Key Laboratory of Software Development Environment Beihang University Beijing China Key Laboratory of Data Science and Intelligent Computing Institute of International Innovation Beihang University Hangzhou Zhejiang China Pengcheng Laboratory Shenzhen Guangdong China United Imaging Healthcare Houston TX USA

ISBN: (数字)9798331520526

ISBN: (纸本)9798331520533

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require extensive diffusion gradient sampling, which can be time-consuming and limits the clinical applicability of tissue microstructure information. Recent advances in deep learning have shown promise in microstructure estimation; however, accurately estimating tissue microstructure from clinically feasible dMRI scans remains challenging without appropriate constraints. This paper introduces a novel framework that achieves high-fidelity and rapid diffusion microstructure imaging by simultaneously leveraging anatomical information from macro-level priors and mutual information across parameters. This approach enhances time efficiency while maintaining accuracy in microstructure estimation. Experimental results demonstrate that our method outperforms four state-of-the-art techniques, achieving a peak signal-to-noise ratio (PSNR) of 30.51±0.58 and a structural similarity index measure (SSIM) of 0.97±0.004 in estimating parametric maps of multiple diffusion models. Notably, our method achieves a 15× acceleration compared to the dense sampling approach, which typically utilizes 270 diffusion gradients.

关键词： Deep learning PSNR Accuracy Three-dimensional displays Magnetic resonance imaging Estimation Reconstruction algorithms Diffusion models Feature extraction Microstructure

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