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arXiv 2025年

作者： Zhu, Junjie Liu, Huayu Wang, Jin Wen, Bangrong Huang, Kaixiang Li, Xiaofei Zhang, Haiyun Lu, Guodong The State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical Engineering Zhejiang University Hangzhou310058 China Zhejiang Key Laboratory of Industrial Big Data and Robot Intelligent Systems Zhejiang University Hangzhou310058 China School of Robotics Ningbo University of Technology Ningbo315211 China Robotics Research Center of Yuyao City Ningbo315400 China

From early Movement Primitive (MP) techniques to modern Vision-Language Models (VLMs), autonomous manipulation has remained a pivotal topic in robotics. As two extremes, VLM-based methods emphasize zero-shot and adaptive manipulation but struggle with fine-grained planning. In contrast, MP-based approaches excel in precise trajectory generalization but lack decision-making ability. To leverage the strengths of the two frameworks, we propose VL-MP, which integrates VLM with Kernelized Movement Primitives (KMP) via a low-distortion decision information transfer bridge, enabling fine-grained robotic manipulation under ambiguous situations. One key of VL-MP is the accurate representation of task decision parameters through semantic keypoints constraints, leading to more precise task parameter generation. Additionally, we introduce a local trajectory feature-enhanced KMP to support VL-MP, thereby achieving shape preservation for complex trajectories. Extensive experiments conducted in complex real-world environments validate the effectiveness of VL-MP for adaptive and fine-grained manipulation. Copyright © 2025, The Authors. All rights reserved.

关键词： Semantics

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CMCache: An Adaptive Cross-Level data Placement Method for Multi-Level Cache

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IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems 2025年

作者： Zeng, Zhaoyang Tan, Yujuan Ma, Zhulin Li, Jiali Zhao, Sanle Liu, Duo Chen, Xianzhang Ren, Ao Chongqing University College of Computer Science Chongqing400044 China Chongqing University Key Laboratory of Dependable Service Computing in Cyber Physical Society Ministry of Education Chongqing400044 China Chongqing Universityof Posts and Telecommunications College of Software Engineering China Chongqing University College of Big Data and Software Engineering Chongqing China

Multi-level cache systems enhance I/O performance by optimizing data placement across various cache levels from a global perspective. However, existing methods often struggle to place data at the optimal cache level promptly due to their reliance on historical access patterns and inflexible placement strategies. These methods face two main challenges: (1) For already cached data with sufficient access history, existing approaches only optimize movement between adjacent cache levels, potentially delaying data arrival at its globally optimal cache level and leading to unnecessary bandwidth consumption and increased latency. (2) For newly entered data without access history, current methods cannot accurately predict their future hotness and simply place them at a fixed cache level (i.e. first or last level), overlooking future accesses of new data and potentially resulting in high cache miss rates or cache pollution. To address these issues, we propose CMCache, an adaptive cross-level data placement method for multi-level cache. CMCache applies distinct placement strategies for cached and new data to reach the optimal level timely, considering their different characteristics. It also logically divides cache space into two sections to manage cached and new data separately, dynamically adjusting section sizes based on access patterns. This approach significantly improves data placement efficiency, achieving up to an 89% reduction in miss rates and a 79% decrease in average response times compared to existing methods. © 2025 IEEE.

关键词： Cache memory

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Single-cell technologies: current and near future

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Science China(Life Sciences) 2025年第1期68卷 1-4页

作者： Chenfei Wang Qi Liu Xiaohui Fan Tieliu Shi KeyLaboratory of Spine and Spinal CordInjury Repairand Regeneration Ministry of EducationOrthopedics DepartmentTongji HospitalBioinformatics DepartmentSchoolofLifeSciencesandTechnologyTongji UniversityShanghai 200082China Frontier Science Center for Stem Cells School of Life Sciences and TechnologyTongji UniversityShanghai 200092China Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji UniversityShanghai 200082China Research Institute of Intelligent Computing Zhejiang LabHangzhou 311121China Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang UniversityJiaxing 314103China Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal UniversityShanghai 200241China Key Laboratory of Advanced Theory and Application in Statistics and Data Science(MOE) School of StatisticsEast China Normal UniversityShanghai 200062China

Single-cell technologies enable the indepth exploration of multiple biological hierarchies at the scale of individual cells,which have deepened our knowledge of cellular diversity,tissue organization,and overall organism function(Sun et al.,2024).In 2009,single-cell RNA sequencing(scRNA-seq)was first developed as a powerful tool to dissect gene expression and uncover transcriptional *** the rapid advancement of technology,single-cell approaches have expanded to encompass other omics,such as genomics,epigenomics,proteomics,and ***,multimodal technologies including spatially resolved transcriptomics and clustered regularly interspaced short palindromic repeats(CRISPR)screening at the single-cell level further advanced our ability to comprehensively understand cellular ***-cell methods provide deeper insights into disease mechanisms across various conditions,including cancer,developmental disorders,and aging-associated *** this issue,we focus on topics related to single-cell methods,covering the following four aspects:(i)single-cell multi-omic sequencing technology;(ii)single-cell spatial technology;(iii)singlecell CRISPR screening technology;(iv)applications of single-cell technology.

关键词： expanded enable insight

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A Triangular Stable Node Network based on Self-supervised Learning for personalized prediction

A Triangular Stable Node Network based on Self-supervised Le...

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2025 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2025

作者： Liu, Qing Gao, Qian Fan, Jun Zhang, Zhiqiang Key Laboratory of Computing Power Network and Information Security Ministry of Education Shandong Computer Science Center National Supercomputer Center in Jinan Qilu University of Technology Shandong Academy of Sciences Jinan250014 China Shandong Engineering Research Center of Big Data Applied Technology Faculty of Computer Science and Technology Qilu University of Technology Shandong Academy of Sciences Jinan250353 China Shandong Provincial Key Laboratory of Industrial Network and Information System Security Shandong Fundamental Research Center for Computer Science Jinan250014 China China Telecom Digital Intelligence Techonology Co Ltd. No.1999 Shunhua road Shandong Jinan250101 China

ISBN: (纸本)9798350368741

In recent years, research has illuminated the potency of implicit data processing in enhancing user preferences. Nevertheless, barriers remain in breaking through the constraints of implicit information. This study aims to bridge this gap by firstly constructing a triangular stable node network model, tailored to manage implicit information with precision. Recognizing the challenge of pinpointing novel structures within large-scale graphs, we propose SLTSNN-a triangular stable node network based on self-supervised learning for personalized prediction. SLTSNN innovates by maximizing mutual information between graph-level and patch-level representations, while augmenting graph representations through extended enhanced representations. Additionally, it incorporates triangular data associations and introduces a triangular allocation attention network, which emphasizes strongly correlated preference features among similar users. Furthermore, SLTSNN employs contrastive learning to maximize mutual information between graph vectors and hidden representations, distinguishing between high-order global and local representations. The model's effectiveness in enhancing user preferences and capturing new graph structures is evidenced by its performance on hit rate and normalized discounted cumulative gain metrics across three datasets. © 2025 IEEE.

关键词： graph contrastive learning graph neural networks recommender systems self-supervised learning

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Multi-Hop Attention Diffusion Graph Neural Networks For Multimodal Fake News Detection

Multi-Hop Attention Diffusion Graph Neural Networks For Mult...

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International Conference on Acoustics, Speech, and Signal Processing (ICASSP)

作者： Zhongqiang Huang Dongli Lu Ying Sha Key Laboratory of Smart Farming for Agricultural Animals Wuhan China Engineering Research Center of Intelligent Technology for Agriculture Ministry of Education Wuhan China Hubei Engineering Technology Research Center of Agricultural Big Data Wuhan China College of Informatics Huazhong Agricultural University Wuhan China

ISBN: (数字)9798350368741

ISBN: (纸本)9798350368758

Fake news often spreads rapidly on social media in various forms, exposing users to a large amount of misinformation and disinformation. Recently, promising results have been achieved in fake news detection. However, most of the approaches only consider one-hop neighborhood information in cross-modal mapping relationships or focus mainly on pairwise interactions of multimodal fake news. However, the fine-grained feature mapping of multimodal fake news may go beyond binary relations. To address these issues, we propose a Multi-Hop Attention Diffusion Graph Neural Networks in this work to capture and complement the multivariate mapping relationships between fine-grained features, while extracting cross-modal higher-order alignment representations for multimodal fake news detection via cross-modal contrastive learning and modal matching. Extensive experiments on three public datasets demonstrate the effectiveness of the proposed approach in the multimodal fake news detection task.

关键词： Visualization Social networking (online) Fuses Spread spectrum communication Contrastive learning Signal processing Feature extraction Graph neural networks Fake news Speech processing

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Predicting Transcription Factor Binding Signals Based on a Novel Encoder-Decoder Framework 2nd

Predicting Transcription Factor Binding Signals Based on a N...

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2nd International Conference on Applied Intelligence, ICAI 2024

作者： Wang, Siguo Li, Zhipeng Zhang, Qinhu Ningbo Institute of Digital Twin Eastern Institute of Technology No. 568 Tongxin Road Zhuangshi Street Zhejiang Ningbo315201 China Big Data and Intelligent Computing Research Center Guangxi Academy of Science Nanning530007 China Institute for Regenerative Medicine Medical Innovation Center and State Key Laboratory of Cardiology School of Medicine Shanghai East Hospital Tongji University Shanghai200123 China

ISBN: (纸本)9789819619061

The transcription process is the initial step in gene expression and the core of the regulatory mechanism, in which transcription factors control gene expression through interactions with particular DNA sequences. Therefore, identification of transcription factor binding sites (TFBSs) provides theoretical basis for further dissection of transcriptional regulatory mechanisms and disease diagnosis. To address the limitations of current research on TFBSs, a novel symmetric Encoder-Decoder framework is proposed for predicting transcription factor binding signals values at base sites. Our approach utilizes word vectors to encode DNA sequences, followed by encoders that progressively extract feature representations from these sequences. We then employ Gated Recurrent Unit (GRU) to capture the contextual dependencies within the sequences, ultimately using decoders to reconstruct the binding signal values for the DNA sequence sites. In order to access the effectiveness of the proposed symmetric Encoder-Decoder framework, some experiments were conducted on 20 ChIP-seq datasets, and the results show that the proposed novel method outperformers several existing advanced methods. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2025.

关键词： DNA sequences

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A Self-Supervised Transfer Learning Framework for Gland Segmentation in Colorectal Cancer Histopathology with Limited Labeled data 2nd

A Self-Supervised Transfer Learning Framework for Gland Segm...

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2nd International Conference on Applied Intelligence, ICAI 2024

作者： Wen, Huer Wu, Yan Huang, De-Shuang Institute for Regenerative Medicine Medical Innovation Center and State Key Laboratory of Cardiology Shanghai East Hospital School of Medicine Tongji University Shanghai200123 China Big Data and Intelligent Computing Research Center Guangxi Academy of Science Nanning530007 China Ningbo Institute of Digital TwinEastern Institute of Technology No. 568 Tongxin Road Zhuangshi Street Zhejiang Ningbo315201 China

ISBN: (纸本)9789819619061

Accurate gland segmentation in colorectal cancer histopathology images is crucial for diagnosis and grading but is hampered by the limited availability of annotated data. To develop a robust and accurate gland segmentation method that effectively leverages unlabeled data to overcome the limitations of small annotated datasets. We propose a novel framework that combines self-supervised learning and transfer learning. A vision transformer is pre-trained using DINOv2 on a large unlabeled dataset (IMP-CRS-2024) and then fine-tuned on the GlaS dataset using a lightweight decoder and a boundary-aware loss function that combines Dice loss and a distance transform-weighted boundary loss. Our method achieves state-of-the-art performance on the GlaS dataset, surpassing existing methods in terms of F1-score, Object Dice, and Object Hausdorff distance. An ablation study confirms the benefits of both the self-supervised pre-training and the boundary-aware loss. Our approach effectively addresses the challenge of limited annotated data in gland segmentation, offering a promising solution for improving the accuracy and efficiency of colorectal cancer diagnosis. The framework can be generalized to other histopathology image analysis tasks and cancer types. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2025.

关键词： Self-supervised learning

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Salix-Leaf: Find Main Veins of Signal Clusters for Practical Parallel Decoding

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IEEE Transactions on Mobile computing 2025年

作者： Li, Yajun Zhao, Jumin Li, Dengao Wu, Hejun Xu, Shuang Bai, Ruiqin Taiyuan University of Technology College of Electronic Information and Optical Engineering Taiyuan China Key Laboratory of Big Data Fusion Analysis and Application of Shanxi Province Taiyuan China Intelligent Perception Engineering Technology Center of Shanxi Taiyuan China Taiyuan University of Technology College of Computer Science and Technology College of Data Science Taiyuan China Sun Yat-sen University Department of Computer Science Guangzhou China

Parallel decoding of backscatter improves communication throughput by enabling concurrent transmission of backscatter tags. In practical applications of parallel decoding, it is extremely difficult to distinguish collided signals in superclusters where multiple signal clusters overlap. Existing methods are usually effective for superclusters with uniformly distributed signals. Nevertheless, there are many more scenarios in which signals in superclusters tend to gather unevenly, and existing methods cannot work. Such uneven clustering of signals occurs due to the following two possible causes: (1) signal-strengthdifferences (SSDs) among tags;or (2) cluster drifting (CD) driven by interferences from other objects within communication environments. This paper proposes a novel scheme called SalixLeaf, which aims to identify the main veins of signal clusters to address this problem of superclusters with unevenly distributed signals. Salix-Leaf identifies the main vein of each signal cluster for fine-grained clustering so that the direction of the main veins can be used to verify the accuracy of clustering. In addition, SalixLeaf employs a supercluster decomposer that divides signals into different segments for clustering analysis, enhancing robustness and practicability. Experimental results show that Salix-Leaf achieves a 1.2-fold increase in throughput and a 25% reduction in bit error rate (BER) compared to the state-of-the-art. © 2002-2012 IEEE.

关键词： Backscattering

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Physics-inspired Machine Learning for Quantum Error Mitigation

arXiv

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arXiv 2025年

作者： Xu, Xiao-Yue Xue, Xin Chen, Tianyu Ding, Chen Li, Tian Zhou, Haoyi Huang, He-Liang Bao, Wan-Su Henan Key Laboratory of Quantum Information and Cryptography Zhengzhou Henan450000 China Department of Computer Science Beihang University Beijing100191 China Beijing Advanced Innovation Center for Big Data and Brain Computing Beijing100191 China Department of Software Beihang University Beijing100191 China

Noise is a major obstacle in current quantum computing, and Machine Learning for Quantum Error Mitigation (ML-QEM) promises to address this challenge, enhancing computational accuracy while reducing the sampling overheads of standard QEM methods. Yet, existing models lack physical interpretability and rely heavily on extensive datasets, hindering their scalability in large-scale quantum circuits. To tackle these issues, we introduce the Neural Noise Accumulation Surrogate (NNAS), a physics-inspired neural network for ML-QEM that incorporates the structural characteristics of quantum noise accumulation within multi-layer circuits, endowing the model with physical interpretability. Experimental results demonstrate that NNAS outperforms current methods across a spectrum of metrics, including error mitigation capability, quantum resource consumption, and training dataset size. Notably, for deeper circuits where QEM methods typically struggle, NNAS achieves a remarkable reduction of over half in errors. NNAS also demands substantially fewer training data, reducing dataset reliance by at least an order of magnitude, due to its ability to rapidly capture noise accumulation patterns across circuit layers. This work pioneers the integration of quantum process-derived structural characteristics into neural network architectures, broadly enhancing QEM's performance and applicability, and establishes an integrative paradigm that extends to various quantum-inspired neural network architectures. © 2025, CC BY.

关键词： Quantum computers

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Single-cell omics: experimental workflow, data analyses and applications

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Science China(Life Sciences) 2025年第1期68卷 5-102页

作者： Fengying Sun Haoyan Li Dongqing Sun Shaliu Fu Lei Gu Xin Shao Qinqin Wang Xin Dong Bin Duan Feiyang Xing Jun Wu Minmin Xiao Fangqing Zhao Jing-Dong J.Han Qi Liu Xiaohui Fan Chen Li Chenfei Wang Tieliu Shi Department of Clinical Laboratory the Affiliated Wuhu Hospital of East China Normal University(The Second People’s Hospital of Wuhu City)Wuhu 241000China Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration(Tongji University) Ministry of EducationOrthopaedic DepartmentTongji HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji UniversityShanghai 200082China Frontier Science Center for Stem Cells School of Life Sciences and TechnologyTongji UniversityShanghai 200092China Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji UniversityShanghai 200082China Research Institute of Intelligent Computing Zhejiang LabHangzhou 311121China Shanghai Research Institute for Intelligent Autonomous Systems Shanghai 201210China Center for Single-cell Omics School of Public HealthShanghai Jiao Tong University School of MedicineShanghai 200025China National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang UniversityJiaxing 314103China Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal UniversityShanghai 200241China Beijing Institutes of Life Science Chinese Academy of SciencesBeijing 100101China Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesCenter for Quantitative Biology(CQB)Peking UniversityBeijing 100871China Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases Women’s HospitalZhejiang University School of MedicineHangzhou 310006China Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of StatisticsEast China Normal U

Cells are the fundamental units of biological systems and exhibit unique development trajectories and molecular *** exploration of how the genomes orchestrate the formation and maintenance of each cell,and control the cellular phenotypes of various organismsis,is both captivating and *** the inception of the first single-cell RNA technology,technologies related to single-cell sequencing have experienced rapid advancements in recent *** technologies have expanded horizontally to include single-cell genome,epigenome,proteome,and metabolome,while vertically,they have progressed to integrate multiple omics data and incorporate additional information such as spatial scRNA-seq and CRISPR ***-cell omics represent a groundbreaking advancement in the biomedical field,offering profound insights into the understanding of complex diseases,including ***,we comprehensively summarize recent advances in single-cell omics technologies,with a specific focus on the methodology *** overview aims to guide researchers in selecting appropriate methods for single-cell sequencing and related data analysis.

关键词： single-cell sequencing genome epigenome proteomics metabolomics multimodal spatial transcriptomics CRISPR screening

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