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Network and Systems Medicine 2021年第1期4卷 2-50页

作者： Zanin, Massimiliano Aitya, Nadim A.A. Basilio, José Baumbach, Jan Benis, Arriel Behera, Chandan K. Bucholc, Magda Castiglione, Filippo Chouvarda, Ioanna Comte, Blandine Dao, Tien-Tuan Ding, Xuemei Pujos-Guillot, Estelle Filipovic, Nenad Finn, David P. Glass, David H. Harel, Nissim Iesmantas, Tomas Ivanoska, Ilinka Joshi, Alok Boudjeltia, Karim Zouaoui Kaoui, Badr Kaur, Daman Maguire, Liam P. McClean, Paula L. McCombe, Niamh De Miranda, João Luís Moisescu, Mihnea Alexandru Pappalardo, Francesco Polster, Annikka Prasad, Girijesh Rozman, Damjana Sacala, Ioan Sanchez-Bornot, Jose M. Schmid, Johannes A. Sharp, Trevor Solé-Casals, Jordi Spiwok, Vojtěch Spyrou, George M. Stalidzans, Egils Stres, Blaa Sustersic, Tijana Symeonidis, Ioannis Tieri, Paolo Todd, Stephen Van Steen, Kristel Veneva, Milena Wang, Da-Hui Wang, Haiying Wang, Hui Watterson, Steven Wong-Lin, Kongfatt Yang, Su Zou, Xin Schmidt, Harald H.H.W. Centro de Tecnología Biomédica Universidad Politécnica de Madrid Madrid Spain Intelligent Systems Research Centre School of Computing Engineering and Intelligent Systems Ulster University Ulster United Kingdom Center for Physiology and Pharmacology Institute of Vascular Biology and Thrombosis Research Medical University of Vienna Vienna Austria TUM School of Life Sciences Weihenstephan Technical University of Munich Freising Germany Holon Israel CNR National Research Council IAC Institute for Applied Computing Rome Italy Lab of Computing Medical Informatics and Biomedical Imaging Technologies School of Medicine Aristotle University of Thessaloniki Thessaloniki Greece Université Clermont Auvergne INRAE UNH Plateforme d'Exploration du Métabolisme MetaboHUB Clermont Clermont-Ferrand France Université de Technologie de Compiègne Compiègne France Labex MS2T Control of Technological Systems-of-Systems CNRS and Université de Technologie de Compiègne Compiègne France Faculty of Engineering University of Kragujevac Kragujevac Serbia Kragujevac Serbia Steinbeis Advanced Risk Technologies Institute Doo Kragujevac Kragujevac Serbia Pharmacology and Therapeutics School of Medicine Galway Neuroscience Centre National University of Ireland Galway Ireland School of Computing Ulster University Ulster United Kingdom Holon Israel Department of Mathematics and Natural Sciences Kaunas University of Technology Kaunas Lithuania Faculty of Computer Science and Engineering Ss. Cyril and Methodius University Skopje Macedonia Medicine Faculty Université Libre de Bruxelles CHU de Charleroi Charleroi Belgium Northern Ireland Centre for Stratified Medicine Biomedical Sciences Research Institute Ulster University Ulster United Kingdom Escola Superior de Tecnologia e Gestão Instituto Politécnico de Portalegre Portalegre Portugal Instituto Superior Técnico Universidade de Lisboa Lisboa Portugal Faculty of Automatic Control and Computers University Politehnica of B

Background: Systems Medicine is a novel approach to medicine, that is, an interdisciplinary field that considers the human body as a system, composed of multiple parts and of complex relationships at multiple levels, and further integrated into an environment. Exploring Systems Medicine implies understanding and combining concepts coming from diametral different fields, including medicine, biology, statistics, modeling and simulation, and data science. Such heterogeneity leads to semantic issues, which may slow down implementation and fruitful interaction between these highly diverse fields. Methods: In this review, we collect and explain more than100 terms related to Systems Medicine. These include both modeling and data science terms and basic systems medicine terms, along with some synthetic definitions, examples of applications, and lists of relevant references. Results: This glossary aims at being a first aid kit for the Systems Medicine researcher facing an unfamiliar term, where he/she can get a first understanding of them, and, more importantly, examples and references for digging into the topic. © Massimiliano Zanin et al., 2021;Published by Mary Ann Liebert, Inc. 2021.

关键词： Semantics

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PSGAN: A generative adversarial network for remote sensing image pan-sharpening

arXiv

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arXiv 2018年

作者： Liu, Xiangyu Wang, Yunhong Liu, Qingjie Beijing Advanced Innovation Center for Big Data and Brain Computing Beijing Key Laboratory of Digital Media School of Computer Science and Engineering Beihang University Beijing100191 China

Remote sensing image fusion (also known as pan-sharpening) aims to generate a high resolution multi-spectral image from inputs of a high spatial resolution single band panchromatic (PAN) image and a low spatial resolution multi-spectral (MS) image. In this paper, we propose PSGAN, a generative adversarial network (GAN) for remote sensing image pan-sharpening. To the best of our knowledge, this is the first attempt at producing high quality pan-sharpened images with GANs. The PSGAN consists of two parts. Firstly, a two-stream fusion architecture is designed to generate the desired high resolution multi-spectral images, then a fully convolutional network serving as a discriminator is applied to distinct "real" or "pan-sharpened" MS images. Experiments on images acquired by Quickbird and GaoFen-1 satellites demonstrate that the proposed PSGAN can fuse PAN and MS images effectively and significantly improve the results over the state of the art traditional and CNN based pan-sharpening methods. Copyright © 2018, The Authors. All rights reserved.

关键词： Generative adversarial networks

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Spatiotemporal Knowledge Distillation for Efficient Estimation of Aerial Video Saliency

arXiv

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arXiv 2019年

作者： Li, Jia Fu, Kui Zhao, Shengwei Ge, Shiming State Key Laboratory of Virtual Reality Technology and Systems School of Computer Science and Engineering Beihang University Beijing100191 China Beijing Advanced Innovation Center for Big Data and Brain Computing Beihang University Beijing100191 China Institute of Information Engineering Chinese Academy of Sciences Beijing100095 China School of Cyber Security at University of Chinese Academy of Sciences Beijing100095 China

—The performance of video saliency estimation techniques has achieved significant advances along with the rapid development of Convolutional Neural Networks (CNNs). However, devices like cameras and drones may have limited computational capability and storage space so that the direct deployment of complex deep saliency models becomes infeasible. To address this problem, this paper proposes a dynamic saliency estimation approach for aerial videos via spatiotemporal knowledge distillation. In this approach, five components are involved, including two teachers, two students and the desired spatiotemporal model. The knowledge of spatial and temporal saliency is first separately transferred from the two complex and redundant teachers to their simple and compact students, and the input scenes are also degraded from high-resolution to low-resolution to remove the probable data redundancy so as to greatly speed up the feature extraction process. After that, the desired spatiotemporal model is further trained by distilling and encoding the spatial and temporal saliency knowledge of two students into a unified network. In this manner, the inter-model redundancy can be further removed for the effective estimation of dynamic saliency on aerial videos. Experimental results show that the proposed approach outperforms ten state-of-the-art models in estimating visual saliency on aerial videos, while its speed reaches up to 28,738 FPS on the GPU platform. Copyright © 2019, The Authors. All rights reserved.

关键词： Students

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Learning Structured Twin-Incoherent Twin-Projective Latent Dictionary Pairs for Classification

Learning Structured Twin-Incoherent Twin-Projective Latent D...

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IEEE International Conference on data Mining (ICDM)

作者： Zhao Zhang Yulin Sun Zheng Zhang Yang Wang Guangcan Liu Meng Wang School of Computer Science and Technology Soochow University Suzhou China Key Laboratory of Knowledge Engineering with Big Data (Ministry of Education) Hefei University of Technology School of Computer Science and Information Engineering Hefei University of Technology Hefei China Bio-Computing Research Center Harbin Institute of Technology (Shenzhen) Shenzhen China School of Information and Control Nanjing University of Information Science and Technology Nanjing China

In this paper, we extend the popular dictionary pair learning (DPL) into the scenario of twin-projective latent flexible DPL under a structured twin-incoherence. Technically, a novel framework called Twin-Projective Latent Flexible DPL (TP-DPL) is proposed, which minimizes the twin-incoherence constrained flexibly-relaxed reconstruction error to avoid the possible over-fitting issue and produce accurate reconstruction. In this setting, TP-DPL integrates the twin-incoherence based latent flexible DPL and the joint embedding of codes as well as salient features by twin-projection into a unified model in an adaptive neighborhood-preserving manner. Therefore, TP-DPL can unify the procedures of salient feature representation and classification. The twin-incoherence constraint on coefficients and features can explicitly ensure high intra-class compactness and inter-class separation over them. TP-DPL also integrates the adaptive weighting to preserve local neighborhood of both coefficients and salient features within each class explicitly. For efficiency, TP-DPL selects the Frobenius-norm and abandons the costly l0/l1-norm for group sparse representation. Another byproduct is that TP-DPL can directly apply the class-specific twin-projective reconstruction residual to compute the label of data. Extensive results on public databases show that TP-DPL can deliver the state-of-the-art performance.

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Inexact Orthant-Wise Quasi-Newton Method

Inexact Orthant-Wise Quasi-Newton Method

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2018 2nd International Conference on Applied Mathematics, Modelling and Statistics Application (AMMSA 2018)

作者： Faguo Wu Wang Yao Xiao Zhang Chenxu Wang Zhiming Zheng Key Laboratory of Mathematics Informatics and Behavioral SemanticsMinistry of EducationSchool of Mathematics and Systems ScienceBeihang University Beijing Advanced Innovation Center for Big Data and Brain Computing Beihang University Big Data Management Department Information Technology Department China Minsheng Bank

The Orthant-Wise Limited-memory QuasiNewton method(OWL-QN), based on the L-BFGS method, is an effective algorithm for solving the '1-regularized sparse learning problem. In order to deal with the '1-regularization, OWL-QN restrict the point to an orthant on which the quadratic model is valid and differentiable. In this paper, we propose an Inexact Orthant-Wise Limited-memory Quasi-Newton method(IOWLQN). This method, at every iteration, compute an approximate solution satisfied the inexactness conditions to estimate the exact solution. We give brief proof to the convergence and report the numerical results.

关键词： orthant-based sparse optimization inexact Newton proximal gadient

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OpenHI2 - Open source histopathological image platform

OpenHI2 - Open source histopathological image platform

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IEEE International Conference on Bioinformatics and Biomedicine

作者： Pargorn Puttapirat Haichuan Zhang Jingyi Deng Yuxin Dong Jiangbo Shi Hongyu He Zeyu Gao Chunbao Wang Xiangrong Zhang Chen Li National Engineering Lab for Big Data Analytics Xi'an Jiao tong University Shaanxi Province Key Laboratory of Satellite and Terrestrial Network Tech. R&D Xi'an Jiaotong University Department of Power System and Automation School of Electrical Engineering Xi'an Jiaotong University Department of Pathology the First Affiliated Hospital of Xi'an Jiaotong University Institute of Intelligent Information Processing Xidian University

ISBN: (纸本)9781728118680

Transition from conventional to digital pathology requires a new category of biomedical informatic infrastructure which could facilitate delicate pathological routine. Pathological diagnoses are sensitive to many external factors and is known to be subjective. Only systems that can meet strict requirements in pathology would be able to run along pathological routines and eventually digitized the area, and the developed platform should comply with existing pathological routines and international standards. Currently, there are a number of available software tools which can perform histopathological tasks including virtual slide viewing, annotating, and basic image analysis, however, none of them can serve as a digital platform for pathology. Here we describe OpenHI2, an enhanced version Open Histopathological Image platform which is capable of supporting all basic pathological tasks and file formats;ready to be deployed in medical institutions on a standard server environment or cloud computing infrastructure. In this paper, we also describe the development decisions for the platform and propose solutions to overcome technical challenges including responsive region retrieval and viewing, virtual slide magnification, recording of diagnostic areas. These factors would promote OpenHI2 be used as a platform for histopathological images in real-world clinical settings. Furthermore, in research, OpenHI2 inherited the annotation functionality from the previous version, thus acquired annotations can be directly utilized by the newly added machine learning module which include popular machine learning models to perform tasks such as histology image classification and segmentation in the same environment. Addition can be made to the platform since each component is modularized and fully documented. OpenHI2 is free, open-source, and available at .

关键词： OpenHI digital pathology histopathological image analysis open source software open source software pathology Platform Software Tools open source Religious Missions External factors images

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Predicting ICU mortality by supervised bidirectional LSTM networks 1

Predicting ICU mortality by supervised bidirectional LSTM ne...

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1st Joint Workshop on AI in Health, AIH 2018

作者： Zhu, Yao Fan, Xiaoliang Wu, Jinzhun Liu, Xiao Shi, Jia Wang, Cheng Fujian Key Laboratory of Sensing and Computing for Smart Cities Xiamen University Xiamen China First Affiliated Hospital Xiamen University Xiamen China School of Information Technology Deakin University Melbourne Australia Digital Fujian Institute of Healthcare and Biomedical Big Data Research Xiamen University Xiamen China School of Information Science and Engineering Lanzhou University Lanzhou China

Mortality prediction in the Intensive Care Unit (ICU) is considered as one of critical steps for the treatment of patients in serious condition. It is a big challenge to model time-series variables for mortality prediction in ICU, because physiological variables such as heart rate and blood pressure are sampled with inconsistent time frequencies. In addition, it is difficult to capture the timing changes of clinical data and to interpret the prediction result of ICU mortality. To deal with these challenges, in this paper, we propose a novel ICU mortality prediction algorithm combining bidirectional LSTM (Long Short-Term Memory) model with supervised learning. First, we preprocess 37 time-series variables related to patients’ signs. Second, we construct the Bidirectional LSTM model with supervision technique to accurately reflect significant changes in patients’ signs. Finally, we train and evaluate our model using a real-world dataset containing 4,000 ICU patients. Experimental results show that our proposed method can significantly outperform many baseline methods. © CEUR-WS. All rights reserved.

关键词： Forecasting

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HERMES: Pedestrian Real-Time Offline Positioning and Moving Trajectory Tracking System Based on MEMS Sensors

HERMES: Pedestrian Real-Time Offline Positioning and Moving ...

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International Conference on Mobile Ad-hoc and Sensor Networks, MSN

作者： Xinxin Liu Xiaolong Xu Jiangsu Key Laboratory of Big Data Security and Intelligent Processing Nanjing University of Posts and Telecommunications Nanjing China School of Computer Science Nanjing University of Posts and Telecommunications Nanjing China

ISBN: (纸本)9781728105499;9781728105482

With the development of positioning technology, sensor-based positioning has become the most commonly used positioning method because it is more low-cost and efficient with the popularity of smart phones. In this paper, we construct a pedestrian real-time offline positioning and moving trajectory tracking system (HERMES) which only relies on the sensors inside smart phones. In HERMES, based on Pedestrian Dead Reckoning (PDR) model, a stable and accurate pedestrian gait recognition is achieved through the rare double sliding window, the pedestrian step length is estimated in real time by a training pedestrian step length model, and the pedestrian real-time course angle is available through orientation sensor inside smart phones. Thus, if given a pedestrian's initial position, the system can implement the real-time offline pedestrian positioning and moving trajectory tracking. Experiments show the pedestrian gait recognition algorithm implemented in this paper has a high accuracy and the positioning effect is satisfactory. The moving trajectory tracked by the HERMES has a small deviation from the experimenter's actual trajectory.

关键词： Acceleration Real-time systems Gait recognition Smart phones Estimation Trajectory tracking Legged locomotion

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Survey of key technologies on millimeter-wave CMOS integrated circuits

Survey of key technologies on millimeter-wave CMOS integrate...

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2017年第二届可靠性工程国际会议

作者： Fei Yu Lei Gao Lixiang Li Shuo Cai Wei Wang Chunhua Wang Hunan Provincial Key Laboratory of Intelligent Processing of Big Data on Transportation & School of Computer and Communication Engineering Changsha University of Science and Technology College of Information Science and Engineering Hunan University

In order to provide guidance for the development of high performance millimeter-wave complementary metal oxide semiconductor(MMW-CMOS) integrated circuits(IC), this paper provides a survey of key technologies on MMW-CMOS IC. Technical background of MMW wireless communications is described. Then the recent development of the critical technologies of the MMW-CMOS IC are introduced in detail and compared. A summarization is given, and the development prospects on MMWCMOS IC are also discussed.

关键词： Survey of key technologies on millimeter-wave CMOS integrated circuits

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Graphical representation and hierarchical decomposition mechanism for vertex-cover solution space

arXiv

引用

arXiv 2019年

作者： Wei, Wei Feng, Xiangnan Wang, Jiannan Liu, Xue Zheng, Zhiming School of Mathematical Sciences Beihang University Beijing100191 China Key Laboratory of Mathematics Informatics and Behavioral Semantics Ministry of Education 100191 China Research Institute of Frontier Science Beihang University Beijing100191 China Beijing Advanced Innovation Center for Big Data and Brain Computing Beihang University Beijing100191 China Peng Cheng Laboratory Guangdong Shenzhen518055 China Center for Humans and Machines Max Planck Institute for Human Development Berlin14195 Germany

In this paper, solution space organization of minimum vertex-cover problem is deeply investigated using the König-Egérvary (KE) graph and theorem, in which a hierarchical decomposition mechanism named KE-layer structure of general graphs is proposed to reveal the complexity of vertex-cover. An algorithm to verify the KE graph is given by the solution space expression of vertex-cover, and the relation between multi-layer KE graphs and maximal matching is illustrated and proved. Furthermore, a framework to calculate the KE-layer number and approximate the minimal vertex-cover is provided, with different strategies of switching nodes and counting energy. The phase transition phenomenon between different KE-layers are studied with the transition points located, and searching of vertex-cover got by this strategy presents comparable advantage against several other methods. The graphical representation and hierarchical decomposition provide a new perspective to illustrate the intrinsic complexity for large-scale graphs/systems recognition. Copyright © 2019, The Authors. All rights reserved.

关键词： Graphic methods

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