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arXiv 2024年

作者： Wang, Jingyao Guo, Huijie Qiang, Wenwen Li, Jiangmeng Zheng, Changwen Xiong, Hui Hua, Gang University of Chinese Academy of Sciences Beijing China National Key Laboratory of Space Integrated Information System Institute of Software Chinese Academy of Sciences Beijing China Beijing Advanced Innovation Center for Big Data and Brain Computing Beihang University Beijing China Thrust of Artificial Intelligence Hong Kong University of Science and Technology Guangzhou China Department of Computer Science and Engineering The Hong Kong University of Science and Technology Hong Kong Wormpex AI Research LLC BellevueWA98004 United States

Humans excel at adapting perceptions and actions to diverse environments, enabling efficient interaction with the external world. This adaptive capability relies on the biological nervous system (BNS), which activates different brain regions for distinct tasks. Meta-learning similarly trains machines to handle multiple tasks but relies on a fixed network structure, not as flexible as BNS. To investigate the role of flexible network structure (FNS) in meta-learning, we conduct extensive empirical and theoretical analyses, finding that model performance is tied to structure, with no universally optimal pattern across tasks. This reveals the crucial role of FNS in meta-learning, ensuring meta-learning to generate the optimal structure for each task, thereby maximizing the performance and learning efficiency of meta-learning. Motivated by this insight, we propose to define, measure, and model FNS in meta-learning. First, we define that an effective FNS should possess frugality, plasticity, and sensitivity. Then, to quantify FNS in practice, we present three measurements for these properties, collectively forming the structure constraint with theoretical supports. Building on this, we finally propose Neuromodulated Meta-Learning (NeuronML) to model FNS in meta-learning. It utilizes bi-level optimization to update both weights and structure with the structure constraint. Extensive theoretical and empirical evaluations demonstrate the effectiveness of NeuronML on various tasks. Code is publicly available at https://***/WangJingyao07/NeuronML. Copyright © 2024, The Authors. All rights reserved.

关键词： Contrastive Learning

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Cosmology with fast radio bursts in the era of SKA

arXiv

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arXiv 2023年

作者： Zhang, Ji-Guo Zhao, Ze-Wei Li, Yichao Zhang, Jing-Fei Li, Di Zhang, Xin Department of Physics College of Sciences Northeastern University Shenyang110819 China Northeastern University Shenyang110819 China National Astronomical Observatories Chinese Academy of Sciences Beijing100101 China University of Chinese Academy of Sciences Beijing100049 China Research Center for Intelligent Computing Platforms Zhejiang Laboratory Hangzhou311100 China National Frontiers Science Center for Industrial Intelligence and Systems Optimization Northeastern University Shenyang110819 China Key Laboratory of Data Analytics and Optimization for Smart Industry Ministry of Education Northeastern University Shenyang110819 China

We present a forecast of the cosmological parameter estimation using fast radio bursts (FRBs) from the upcoming Square Kilometre Array (SKA), focusing on the issues of dark energy, the Hubble constant, and baryon density. We simulate 105 and 106 localized FRBs from a 10-year SKA observation, and find that: (i) using 106 FRB data alone can tightly constrain dark-energy equation of state parameters better than CMB+BAO+SNe, providing an independent cosmological probe to explore dark energy;(ii) combining the FRB data with gravitational-wave standard siren data from 10-year observation with the Einstein Telescope, the Hubble constant can be constrained to a sub-percent level, serving as a powerful low-redshift probe;(iii) using 106 FRB data can constrain the baryon density Ωbh to a precision of ∼ 0.1%. Our results indicate that SKA-era FRBs will provide precise cosmological measurements to shed light on both dark energy and the missing baryon problem, and help resolve the Hubble tension. Copyright © 2023, The Authors. All rights reserved.

关键词： Cosmology

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LungX-Net: Lung Cancer Diagnosis from CT and Histopathological Images via Attention Based Multi-Level Feature Fusion Network

LungX-Net: Lung Cancer Diagnosis from CT and Histopathologic...

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IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

作者： Sohaib Asif Vicky Yang Wang Dong Xu Taizhou Campus of Zhejiang Cancer Hospital (Taizhou Cancer Hospital) Taizhou Key Laboratory of Minimally Invasive Interventional Therapy & Artificial Intelligence Taizhou China Center of Intelligent Diagnosis and Therapy (Taizhou) Hangzhou Institute of Medicine (HIM) Chinese Academy of Sciences Taizhou China Wenling Institute of Big Data and Artificial Intelligence in Medicine Taizhou China Department of Diagnostic Ultrasound Imaging & Interventional Therapy Zhejiang Cancer Hospital Hangzhou Institute of Medicine (HIM) Chinese Academy of Sciences Hangzhou China

ISBN: (数字)9798350386226

ISBN: (纸本)9798350386233

Lung cancer ranks among the top causes of cancer mortality worldwide. However, early detection can significantly boost survival rates, potentially increasing them by as much as 70%. While deep learning algorithms have shown promise in detecting lung cancer from CT scans, current methods are often inefficient, and single-model approaches struggle with complex medical images. Leveraging diverse model features can enhance accuracy and simplify detection. This paper introduces LungX-Net, an innovative and cost-effective deep learning model aimed at improving lung cancer diagnostic accuracy using CT and histopathological images. The proposed model unifies two networks into a unified, trainable feature extraction architecture, employing model compression to preserve essential core blocks. This approach enhances the model’s ability to propagate strong and robust features while significantly reducing computational resource requirements. The model also integrates a Convolutional Block Attention Module (CBAM) to enhance feature extraction by emphasizing the most important regions, which further improves overall accuracy. The integration of these techniques optimizes diagnostic performance while strategically minimizing complexity, making LungX-Net a powerful tool for efficient and precise lung cancer diagnosis. The proposed LungX-Net was evaluated on both CT and histopathological datasets, achieving a recognition accuracy of 99.09% on the CT dataset and 99.30% on the histopathological dataset. LungX-Net demonstrated superior performance compared to previous approaches, achieving greater accuracy with fewer parameters and faster testing times, highlighting its efficiency and cost-effectiveness.

关键词： Deep learning Accuracy Computed tomography Computational modeling Lungs Lung cancer Mortality Feature extraction Medical diagnostic imaging Testing

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Coherent H ∞ control for Markovian jump linear quantum systems

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IFAC-PapersOnLine 2020年第2期53卷 269-274页

作者： Yanan Liu Daoyi Dong Ian R. Petersen Qing Gao Steven X. Ding Hidehiro Yonezawa School of Engineering and Information Technology University of New South Wales Canberra ACT 2600 Australia Center for Quantum Computation and Communication Technology Australian Research Council Canberra ACT 2600 Australia Institute for Automatic Control and Complex Systems (AKS) University of Duisburg-Essen. 47057 Duisburg Germany Research School of Electrical Energy and Materials Engineering The Australian National University Canberra ACT 2601 Australia School of Automation Science and Electrical Engineering State Key Laboratory of Software Development Environment Beijing and also with Advanced Innovation Center for Big Data and Brain Computing Beihang University Beijing 100191 China

The purpose of this paper is to design a coherent feedback controller for a Markovian jump linear quantum system suffering from a fault signal. The control objective is to bound the effect of the disturbance input on the output for the time-varying quantum system. We prove the relation between the H ∞ control problem, the dissipation properties, and the solutions of Riccati differential equations, by which the H ∞ controller of the Markovian jump linear quantum system is given by the solutions of Linear Matrix Inequalities (LMIs).

关键词： Coherent quantum feedback H∞ control fault-tolerant control Markovian jump linear quantum systems

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Impact of temperature and relative humidity on the transmission of COVID-19: A modeling study in China and the United States

arXiv

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arXiv 2020年

作者： Wang, Jingyuan Tang, Ke Feng, Kai Lin, Xin Lv, Weifeng Chen, Kun Wang, Fei School of Computer Science and Engineering Beihang University China Beijing Advanced Innovation Center for Big Data and Brain Computing Beihang University China School of Social Sciences Tsinghua University China State Key Laboratory of Software Development Environment Beihang University China Department of Statistics University of Connecticut United States Center for Population Health University of Connecticut Health Center United States Department of Population Health Sciences Weill Cornell Medical College Cornell University United States

Objectives We aim to assess the impact of temperature and relative humidity on the transmission of COVID-19 across communities after accounting for community-level factors such as demographics, socioeconomic status, and human mobility status. Design A retrospective cross-sectional regression analysis via the Fama-MacBeth procedure is adopted. Setting We use the data for COVID-19 daily symptom-onset cases for 100 Chinese cities and COVID-19 daily confirmed cases for 1,005 U.S. counties. Participants A total of 69,498 cases in China and 740,843 cases in the U.S. are used for calculating the effective reproductive numbers. Primary outcome measures Regression analysis of the impact of temperature and relative humidity on the effective reproductive number (R value). Results Statistically significant negative correlations are found between temperature/relative humidity and the effective reproductive number (R value) in both China and the U.S. Conclusions Higher temperature and higher relative humidity potentially suppress the transmission of COVID-19. Specifically, an increase in temperature by 1 degree Celsius is associated with a reduction in the R value of COVID-19 by 0.026 (95% CI [-0.0395,-0.0125]) in China and by 0.020 (95% CI [-0.0311, -0.0096]) in the U.S.;an increase in relative humidity by 1% is associated with a reduction in the R value by 0.0076 (95% CI [-0.0108,-0.0045]) in China and by 0.0080 (95% CI [-0.0150,-0.0010]) in the U.S. Therefore, the potential impact of temperature/relative humidity on the effective reproductive number alone is not strong enough to stop the pandemic. Copyright © 2020, The Authors. All rights reserved.

关键词： Regression analysis

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Ready for emerging threats to recommender systems? A graph convolution-based generative shilling attack

arXiv

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arXiv 2021年

作者： Wu, Fan Gao, Min Yu, Junliang Wang, Zongwei Liu, Kecheng Wang, Xu Key Laboratory of Dependable Service Computing in Cyber Physical Society Chongqing University Ministry of Education Chongqing401331 China School of Big Data and Software Engineering Chongqing University Chongqing401331 China School of Information Technology and Electrical Engineering The University of Queensland Queensland4072 Australia Informatics Research Centre Henley Business School University of Reading Berkshire ReadingRG6 6UD United Kingdom School of Mechanical Engineering Chongqing University Chongqing400044 China

To explore the robustness of recommender systems, researchers have proposed various shilling attack models and analyzed their adverse effects. Primitive attacks are highly feasible but less effective due to simplistic handcrafted rules, while upgraded attacks are more powerful but costly and difficult to deploy because they require more knowledge from recommendations. In this paper, we explore a novel shilling attack called Graph cOnvolution-based generative shilling ATtack (GOAT) to balance the attacks' feasibility and effectiveness. GOAT adopts the primitive attacks' paradigm that assigns items for fake users by sampling and the upgraded attacks' paradigm that generates fake ratings by a deep learning-based model. It deploys a generative adversarial network (GAN) that learns the real rating distribution to generate fake ratings. Additionally, the generator combines a tailored graph convolution structure that leverages the correlations between co-rated items to smoothen the fake ratings and enhance their authenticity. The extensive experiments on two public datasets evaluate GOAT's performance from multiple perspectives. Our study of the GOAT demonstrates technical feasibility for building a more powerful and intelligent attack model with a much-reduced cost, enables analysis the threat of such an attack and guides for investigating necessary prevention measures. Copyright © 2021, The Authors. All rights reserved.

关键词： Recommender systems

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FABind: fast and accurate protein-ligand binding 23

FABind: fast and accurate protein-ligand binding

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Proceedings of the 37th International Conference on Neural Information Processing Systems

作者： Qizhi Pei Kaiyuan Gao Lijun Wu Jinhua Zhu Yingce Xia Shufang Xie Tao Qin Kun He Tie-Yan Liu Rui Yan Gaoling School of Artificial Intelligence Renmin University of China and Engineering Research Center of Next-Generation Intelligent Search and Recommendation Ministry of Education School of Computer Science and Technology Huazhong University of Science and Technology Microsoft Research AI4Science School of Information Science and Technology University of Science and Technology of China Gaoling School of Artificial Intelligence Renmin University of China Gaoling School of Artificial Intelligence Renmin University of China and Beijing Key Laboratory of Big Data Management and Analysis Methods

Modeling the interaction between proteins and ligands and accurately predicting their binding structures is a critical yet challenging task in drug discovery. Recent advancements in deep learning have shown promise in addressing this challenge, with sampling-based and regression-based methods emerging as two prominent approaches. However, these methods have notable limitations. Sampling-based methods often suffer from low efficiency due to the need for generating multiple candidate structures for selection. On the other hand, regression-based methods offer fast predictions but may experience decreased accuracy. Additionally, the variation in protein sizes often requires external modules for selecting suitable binding pockets, further impacting efficiency. In this work, we propose FABind, an end-to-end model that combines pocket prediction and docking to achieve accurate and fast protein-ligand binding. FABind incorporates a unique ligand-informed pocket prediction module, which is also leveraged for docking pose estimation. The model further enhances the docking process by incrementally integrating the predicted pocket to optimize protein-ligand binding, reducing discrepancies between training and inference. Through extensive experiments on benchmark datasets, our proposed FABind demonstrates strong advantages in terms of effectiveness and efficiency compared to existing methods. Our code is available at Github https://***/QizhiPei/FABind.

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Preface

引用

Science China Technological Sciences 2024年

作者： Gong YiHong Wang GuoYin College of Artificial Intelligence Xi'an Jiaotong University Chongqing Key Laboratory of Computational Intelligence Chongqing University of Posts and Telecommunications Key Laboratory of Cyberspace Big Data Intelligent Security Chongqing University of Posts and Telecommunications College of Computer and Information Science Chongqing Normal University

Large AGI(artificial general intelligence) models, represented by OpenAI's GPT-4, DALL-E, Sora, etc., have amazed the world by exhibiting superior capabilities on a variety of NLP and text-to-image/video generation tasks. The success of these models was achieved by exploiting ultra-scale training data, ultra-scale computational models, and unlimited computing power.

关键词：

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A deep learning system for predicting time to progression of diabetic retinopathy

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NATURE MEDICINE 2024年第2期30卷 358-359页

作者： [Anonymous] Shanghai Belt and Road International Joint Laboratory for Intelligent Prevention and Treatment of Metabolic Disorders Department of Computer Science and Engineering School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Department of Endocrinology and Metabolism Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai Diabetes Institute Shanghai Clinical Center for Diabetes Shanghai China MOE Key Laboratory of AI School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Shanghai China Department of Ophthalmology Huadong Sanatorium Wuxi China Department of Ophthalmology Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China Department of Ophthalmology and Visual Sciences The Chinese University of Hong Kong Hong Kong China Singapore Eye Research Institute Singapore National Eye Centre Singapore Singapore Department of Computer Science and Engineering The Hong Kong University of Science and Technology Hong Kong China Department of Chemical and Biological Engineering The Hong Kong University of Science and Technology Hong Kong China State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-sen University Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science Guangzhou China Department of Ophthalmology Peking Union Medical College Hospital Peking Union Medical College Chinese Academy of Medical Sciences Beijing China Medical Records and Statistics Office Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China Department of Geriatrics Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China National Engineering Research Center for Big Data Technology and System Services Computing Technology and System Lab Cluster and Grid Computing Lab School of Computer Science and Tech

We developed and validated a deep learning system (termed DeepDR Plus) in a diverse, multiethnic, multi-country dataset to predict personalized risk and time to progression of diabetic retinopathy. We show that DeepDR Plus can be integrated into the clinical workflow to promote individualized intervention strategies for the management of diabetic retinopathy.

关键词： Diabetes complications Machine learning Predictive markers

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Investigating 16 Open Clusters in the Kepler/K2 - Gaia DR3 field. I. Membership, Binary, and Rotation

arXiv

引用

arXiv 2023年

作者： Long, Liu Bi, Shaolan Zhang, Jinghua Zhang, Xianfei Zhang, Liyun Ge, Zhishuai Li, Tanda Chen, Xunzhou Li, YaGuang Ye, LiFei Sun, TianCheng Zhou, JianZhao Institute for Frontiers in Astronomy and Astrophysics Beijing Normal University Beijing102206 China Department of Astronomy Beijing Normal University Beijing100875 China South-Western Institute for Astronomy Research Yunnan University Chenggong District Kunming650500 China College of Physics Guizhou University Guiyang550025 China State Key Laboratory of Public Big Data Guizhou University Guiyang550025 China Beijing Planetarium Beijing Academy of Science and Technology Beijing100044 China Research Center for Intelligent Computing Platforms Zhejiang Laboratory Hangzhou311100 China School of Physics University of Sydney NSW2006 Australia Stellar Astrophysics Centre Department of Physics and Astronomy Aarhus University Ny Munkegade 120 Aarhus CDK-8000 Denmark

Using data from the Gaia data Release 3 (Gaia DR3) and Kepler/K2, we present a catalog of 16 open clusters with ages ranging from 4 to 4000 Myr, which provides detailed information on membership, binary systems, and rotation. We assess the memberships in 5D phase space, and estimate the basic parameters of each cluster. Among the 20,160 members, there are 4,381 stars identified as binary candidates and 49 stars as blue straggler stars. The fraction of binaries vary in each cluster, and the range between 9% to 44%. We obtain the rotation periods of 5,467 members, of which 4,304 are determined in this work. To establish a benchmark for the rotation-age-color relation, we construct color-period diagrams. We find that the rotational features of binaries are similar to that of single stars, while features for binaries are more scattered in the rotation period. Moreover, the morphology of the color-period relationship is already established for Upper Scorpius at the age of 19 Myr, and some stars of varying spectral types (i.e. FG-, K-, and M-type) show different spin-down rates after the age of ∼ 110 Myr. By incorporating the effects of stalled spin-down into our analysis, we develop an empirical rotation-age-color relation, which is valid with ages between 700 - 4000 Myr and colors corresponding to a range of 0.5 BP − GRP)0 Copyright © 2023, The Authors. All rights reserved.

关键词： Color

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