In China, the expressway isn’t free. When a vehicle exits, the exit toll station needs to calculate the toll according to the vehicle trajectory obtained by sending a trajectory query task to the trajectory center re...
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To deal with the challenge of information overload, in this paper, we propose a financial news recommendation algorithm which help users find the articles that are interesting to read. To settle the ambiguity problem,...
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To deal with the challenge of information overload, in this paper, we propose a financial news recommendation algorithm which help users find the articles that are interesting to read. To settle the ambiguity problem, a new presented OF-IDF method is employed to represent the unstructured text data in the form of key concepts, synonyms and synsets which are all stored in the domain ontology. For users, the recommendation algorithm build the profiles based on their behaviors to detect the genuine interests and predict current interests automatically and in real time by applying the thinking of relevance feedback. Finally, the experiment conducted on a financial news dataset demonstrates that the proposed algorithm significantly outperforms the performance of a traditional recommender.
In smart grid, privacy implications to individuals and their family is an important issue, due to the fine-grained usage data collection. Wireless communications are considered by many utility companies to obtain info...
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High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to dat...
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High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1 million people of European ancestry. We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also highlight shared genetic architecture between blood pressure and lifestyle exposures. Our findings identify new biological pathways for blood pressure regulation with potential for improved cardiovascular disease prevention in the future.
MicroRNAs can regulate hundreds of target genes and play a pivotal role in a broad range of biological process. However, relatively little is known about how these highly connected miRNAs-target networks are remodelle...
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MicroRNAs can regulate hundreds of target genes and play a pivotal role in a broad range of biological process. However, relatively little is known about how these highly connected miRNAs-target networks are remodelled in the context of various diseases. Here we examine the dynamic alteration of context-specific miRNA regulation to determine whether modified microRNAs regulation on specific biological processes is a useful information source for predicting cancer prognosis. A new concept, Context-specific miRNA activity (CoMi activity) is introduced to describe the statistical difference between the expression level of a miRNA's target genes and non-targets genes within a given gene set (context).
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