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Any-Angle Routing Algorithm for Microfluidic Biochips Driven by Flow Path

Jisuanji Yanjiu yu Fazhan/Computer Research and Development 2025年第4期62卷 978-988页

作者： Youlin, Pan Shuai, Guo Xing, Huang Genggeng, Liu College of Computer and Data Science Fuzhou University Fuzhou350116 China Engineering Research Center of Big Data Intelligence Fuzhou University Ministry of Education Fuzhou350116 China Fujian Key Laboratory of Network Computing and Intelligent Information Processing Fuzhou University Fuzhou350116 China School of Computer Science Northwestern Polytechnical University Xi’an710072 China

Continuous-flow microfluidic biochips (CFMBs) have become a hot research topic in recent years due to their ability to perform biochemical assays automatically and efficiently. For the first time, PathDriver+ takes the requirements of the actual fluid transportation into account in the design process of CFMBs and implements the actual fluid transport and removal, and plans separate flow paths for each transport task, which have been neglected in previous work. However, PathDriver+ does not take full advantage of the flexibility of CFMBs routing because it only considers the optimization of flow channel length for the global routing in the mesh model, except for the detailed routing. In addition, PathDriver+ only considers the X architecture, while the existing work shows that the any-angle routing can utilize the routing resources more efficiently and shorten the flow channel length. To address the above issues, we propose a flow path-driven arbitrary angle routing algorithm, which can improve the utilization of routing resources and reduce the flow channel length while considering the actual fluid transportation requirements. The proposed algorithm constructs a search graph based on constrained Delaunay triangulation to improve the search efficiency of routing solutions while ensuring the routing quality. Then, a Dijkstra-based flow path routing method is used on the constructed search graph to generate a routing result with a short channel length quickly. In addition, in the routing process, channel reuse strategy and intersection optimization strategy are proposed for the flow path reuse and intersection number optimization problems, respectively, to further improve the quality of routing results. The experimental results show that compared with the latest work PathDriver+, the length of channels, the number of ports used, and the number of channel intersections are significantly reduced by 33.21%, 11.04%, and 44.79%, respectively, and the channel reuse rate is i

关键词： High level synthesis

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SSFam: Scribble Supervised Salient Object Detection Family

arXiv

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arXiv 2024年

作者： Liu, Zhengyi Deng, Sheng Wang, Xinrui Wang, Linbo Fang, Xianyong Tang, Bin Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education School of Computer Science and Technology Anhui University Hefei China School of Artificial Intelligence and Big Data Hefei University Hefei China

Scribble supervised salient object detection (SSSOD) constructs segmentation ability of attractive objects from surroundings under the supervision of sparse scribble labels. For the better segmentation, depth and thermal infrared modalities serve as the supplement to RGB images in the complex scenes. Existing methods specifically design various feature extraction and multi-modal fusion strategies for RGB, RGB-Depth, RGB-Thermal, and Visual-Depth-Thermal image input respectively, leading to similar model flood. As the recently proposed Segment Anything Model (SAM) possesses extraordinary segmentation and prompt interactive capability, we propose an SSSOD family based on SAM, named SSFam, for the combination input with different modalities. Firstly, different modal-aware modulators are designed to attain modal-specific knowledge which cooperates with modal-agnostic information extracted from the frozen SAM encoder for the better feature ensemble. Secondly, a siamese decoder is tailored to bridge the gap between the training with scribble prompt and the testing with no prompt for the stronger decoding ability. Our model demonstrates the remarkable performance among combinations of different modalities and refreshes the highest level of scribble supervised methods and comes close to the ones of fully supervised methods. https://***/liuzywen/SSFam Copyright © 2024, The Authors. All rights reserved.

关键词： Image segmentation

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Control Logic Routing for Continuous-Flow Microfluidic Biochips Based on Deep Reinforcement Learning

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Jisuanji Yanjiu yu Fazhan/Computer Research and Development 2025年第4期62卷 950-962页

作者： Cai, Huayang Huang, Xing Liu, Genggeng College of Computer and Data Science Fuzhou University Fuzhou350116 China Engineering Research Center of Big Data Intelligence Fuzhou University Ministry of Education Fuzhou350116 China Fujian Key Laboratory of Network Computing and Intelligent Information Processing Fuzhou University Fuzhou350116 China School of Computer Science Northwestern Polytechnical University Xi’an710072 China

With the advancement of electronic design automation, continuous-flow microfluidic biochips have become one of the most promising platforms for biochemical experiments. This chip manipulates fluid samples in milliliters or nanoliters by utilizing internal microvalves and microchannels, and thus automatically performs basic biochemical experiments, such as mixing and detection. To achieve the correct bioassay function, the microvalves deployed inside the chip are usually managed by a multiplexer-based control logic, and valves receive control signals from a core input through the control channel for accurate switching. Since biochemical reactions typically require high sensitivity, the length of control paths connecting each valve needs to be reduced to ensure immediate signal propagation, and thus to reduce the signal propagation delay. In addition, to reduce the fabrication cost of chips, a vital issue to be addressed in the logic architecture design is how to effectively reduce the total channel length within the control logic. To address the above issues, we propose a deep reinforcement learning-based control logic routing algorithm to minimize the signal propagation delay and total control channel length, thereby automatically constructing an efficient control channel network. The algorithm employs the dueling deep Q-network architecture as the agent of the deep reinforcement learning framework to evaluate the tradeoff between signal propagation delay and total channel length. Besides, the diagonal channel routing is implemented for the first time for control logic, thus fundamentally improving the efficiency of valve switching operations and reducing the fabrication cost of the chip. The experimental results demonstrate that the proposed algorithm can effectively construct a high-performance and low-cost control logic architecture. © 2025 Science Press. All rights reserved.

关键词： Deep reinforcement learning

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NcoVis: A Visual Analysis Framework for Exploring Academic Collaboration Networks under New Collaborative Relationships 25

NcoVis: A Visual Analysis Framework for Exploring Academic C...

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25th IEEE International Conference on Computer Supported Cooperative Work in Design, CSCWD 2022

作者： Yu, Ye Wu, Yao Liang, Xi Ma, Cheng Lu, Qiang Key Laboratory of Knowledge Engineering with Big Data Hefei University of Technology Ministry of Education Hefei China School of Computer Science and Information Hefei University of Technology Hefei China Intelligent Interconnected Systems Laboratory of Anhui Province Hefei University of Technology Hefei China

ISBN: (纸本)9781665405270

Academic collaboration has become one of the topics of large-scale social network analysis. The information extracted from academic collaboration also shows the contextual value in combination with other data. For academic collaborative social networks with intricate collaborative relationships, previous research methods mainly focused on network structure and community discovery, lacking in mining the characteristics of relationships in collaborative networks. There were some limitations in the research perspective. In this work, we propose a collaborative relationship representation method that is more suitable for academic collaborative social networks. It marks the attribute characteristics of nodes in collaborative relationships and highlights collaborative relationships in visualization. By adopting this new representation of collaborative relationships, we designed a visual analysis framework NcoVis, to visualize academic collaborative social networks. We further visually analyze the link relationship groups guided by nodes, and explore the potential representation of the structure and attribute characteristics of link relationships, so that analysts can explore the theme and structural change characteristics of link relationships, communities and the whole network in collaborative social networks. To prove the proposed framework, we conducted a case study on the academic collaboration literature data set, and analyzed the questionnaire with Likert scale through the user evaluation experiment, which verified the effectiveness of our method and the practicability of NcoVis. © 2022 IEEE.

关键词： Visualization

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Multi-scale cyclical similarity prototype refinement for few-shot breast ultrasound image segmentation

Multi-scale cyclical similarity prototype refinement for few...

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International Conference on Signal Processing Proceedings (ICSP)

作者： Yingfeng Ou Xing Yang Jian Zhang Caiqing Jian Lihui Wang Engineering Research Center of Text Computing Ministry of Education Key Laboratory of Intelligent Medical Image Analysis and Precise Diagnosis of Guizhou Province State Key Laboratory of Public Big Data College of Computer Science and Technology Guizhou University Guiyang China

ISBN: (数字)9798350387384

ISBN: (纸本)9798350387391

Few-shot learning based methods can address the reliance on large-scale labeled samples in current breast tumor segmentation. However, previous methods typically rely on a few support samples to extract abstract, coarse-grained semantic prototypes, without considering the interaction between support and query data. In this study, we aim to provide each query image with relevant and information-rich support information. By integrating the difficult point selection module and the multi-scale cyclical prototype refinement module, we progressively refine coarse-grained support prototypes into more informative, fine-grained class prototypes, thereby better matching the highly variable breast ultrasound query data. Experiments on two datasets demonstrate that our proposed multi-scale cyclical similarity prototype refinement network (CSPRNet) achieves remarkable improvements compared to previous state-of-the-art methods. Specifically, using ResNet50 as the backbone, we achieve 57.93%/57.92% and 57.58%/59.24% mIoU for 1-shot and 5-shot segmentation, respectively, on public and private datasets, outperforming the suboptimal method by 8.18%/2.55% and 2.77%/4.48%.

关键词： Image segmentation Ultrasonic imaging Breast tumors Semantics Prototypes Signal processing data mining Few shot learning Residual neural networks

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Deep Vision Guided Mobile robot Dual Axis PID Dynamic Real Time Adjustment Following

Deep Vision Guided Mobile Robot Dual Axis PID Dynamic Real T...

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WRC Symposium on Advanced robotics and Automation (WRC SARA)

作者： Yang Li Guanci Yang Ling He Le Zhao Tianyi Zhao Haoran Sun Key Laboratory of Advanced Manufacturing Technology of the Ministry of Education Guizhou University Guiyang Guizhou China Key Laboratory of Advanced Manufacturing Technology of the Ministry of Education/ State Key Laboratory of Public Big Data / Guizhou Provincial Key Laboratory of Internet+” Collaborative Intelligent Manufacturing Guizhou University Guiyang Guizhou China

The real-time tracking of moving objects by social robots is crucial for ensuring object-oriented services. This paper presents a real-time following algorithm for mobile robots based on deep vision object detection. Firstly, using a binocular depth vision camera, real-time target information from a firstperson perspective is collected, and a lightweight deep learning model is employed to detect the relative position of the human body posture with respect to the social robot. Subsequently, to address the issue of unsmooth trajectory during the tracking process, a dual-axis PID algorithm is developed for cooperative control of the robot’s speed and heading angle. Given the inherent randomness in human body movement, target loss can occur during tracking. To enhance the algorithm’s robustness, a dynamic tracking mechanism is introduced. Finally, we implement a vision-driven two-wheel differential social robot following algorithm on the ROS system and validate it through three real-world experimental scenarios. The mean values of the target acquisition rate, tracked target position, and angle smoothness are found to be 0.81, 0.46, and 1.02, respectively.

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DDoS Detection and Defense Based on FLAD and SDN

DDoS Detection and Defense Based on FLAD and SDN

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International Conference on Fuzzy Systems and Knowledge Discovery (FSKD)

作者： Jie Dong Wenyu Fang Wanling Zheng Jinkun Liu Yanhua Liu College of Computer and Data Science Fuzhou University Fuzhou China Fujian Key Laboratory of Network Computing and Intelligent Information Processing Fuzhou University Fuzhou China Engineering Research Center of Big Data Intelligence Ministry of Education Fuzhou China

ISBN: (数字)9798350356328

ISBN: (纸本)9798350356335

In order to achieve more efficient and accurate DDoS detection while ensuring data privacy, this paper proposes a DDoS detection method based on FLAD. Firstly, this paper uses the FLAD algorithm to train a global DDoS detection model without leaving local traffic data, protecting the privacy and security of traffic data between different hosts, and improving aggregation efficiency by dynamically adjusting the aggregation weights to adapt to different sub-dataset increments. Secondly, a DDoS traffic detection method based on the integration of LSTM and CNN is proposed, which extracts and analyzes the temporal correlation of traffic data by calculating the statistical characteristics of traffic data within a time period, to achieve real-time detection of traffic feature data. Again, combined with the concept of SDN, real-time defense against DDoS based on ODL-API is implemented, and precise matching of DDoS detection results with network entity information is achieved, realizing the technology of real-time and precise issuance of multiple flow rules, effectively blocking DDoS malicious attack traffic, protecting important entities in the topology, and maintaining stable traffic in the topology. This paper focuses on solving the detection problem of DDoS traffic data increments and uneven data distribution through the FLAD algorithm. Experimental results show that the proposed method improves the accuracy of DDoS attack detection by more than 4% and the F1 Score by more than 7% compared to the FedAvg aggregation algorithm.

关键词： Training data privacy Network topology Denial-of-service attack Feature extraction Real-time systems Topology Labeling Computer crime Long short term memory

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Local Entropy Based Fuzzy Connectedness Segmentation for Thyroid Ultrasound Images

Local Entropy Based Fuzzy Connectedness Segmentation for Thy...

引用

IEEE International Conference on Systems, Man and Cybernetics

作者： Yixuan Fu Kai Li Junying Chen Key Laboratory of Big Data and Intelligent Robot (SCUT) Ministry of Education School of Software Engineering South China University of Technology Guangzhou China Department of Ultrasound Third Affiliated Hospital of Sun Yat-sen University Guangzhou China

Although deep learning methods are popular in recent years to achieve dominant image segmentation performance, the carefully annotated training images are very difficult to obtain in clinical medicine, and the deep learning model training demands a lot of computing resources which are not always available. To overcome these difficulties, it is very necessary to investigate segmentation algorithms which do not require any training data. In this work, we improve a semi-automatic conventional segmentation algorithm, fuzzy connectedness segmentation, by introducing the local information entropy of the ultrasound image into the fuzzy affinity membership function. The proposed semi-automatic local entropy based fuzzy connectedness (LEFC) segmentation algorithm is further modified by incorporating the popular deep learning methods to make the LEFC algorithm fully automatic. The proposed semi-automatic LEFC algorithm achieves better performance than other representative fuzzy connectedness segmentation algorithms with the accuracy and IoU values increased by 5.9~14% and 5~10.5%, and achieves very close segmentation performance as compared with the best deep learning model in the experiments (0.2% lower accuracy and 0.2% lower IoU compared to CE-Net). Besides, the automatic LEFC algorithm improves the segmentation results obtained by the corresponding deep learning based coarse segmentation modules with the accuracy and IoU increased by 0.2~8% and 0.1~3.8%, respectively. Furthermore, the experiment results demonstrate that the proposed automatic LEFC algorithm obtains stably good segmentation performance even with limited training data, achieving the accuracy and IoU values (at the stable state) 23.6 % and 18.5% higher than those of the corresponding U-Net model which is trained with the samesized dataset.

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Mobility-aware Seamless Service Migration and Resource Allocation in Multi-edge IoV Systems

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IEEE Transactions on Mobile Computing 2025年第07期24卷 6315-6332页

作者： Chen, Zheyi Huang, Sijin Min, Geyong Ning, Zhaolong Li, Jie Zhang, Yan Fuzhou University College of Computer and Data Science Fuzhou350116 China Ministry of Education Engineering Research Center of Big Data Intelligence Fuzhou350002 China Fuzhou University Fujian Key Laboratory of Network Computing and Intelligent Information Processing Fuzhou350116 China University of Exeter Department of Computer Science Faculty of Environment Science and Economy ExeterEX4 4QF United Kingdom Chongqing University of Posts and Telecommunications School of Communications and Information Engineering Chongqing400065 China Shanghai Jiao Tong University Department of Computer Science and Engineering Shanghai200240 China University of Oslo Department of Informatics Oslo0316 Norway

Mobile Edge Computing (MEC) offers low-latency and high-bandwidth support for Internet-of-Vehicles (IoV) applications. However, due to high vehicle mobility and finite communication coverage of base stations, it is hard to maintain uninterrupted and high-quality services without proper service migration among MEC servers. Existing solutions commonly rely on prior knowledge and rarely consider efficient resource allocation during the service migration process, making it hard to reach optimal performance in dynamic IoV environments. To address these important challenges, we propose SR-CL, a novel mobility-aware seamless Service migration and Resource allocation framework via Convex-optimization-enabled deep reinforcement Learning in multi-edge IoV systems. First, we decouple the Mixed Integer Nonlinear Programming (MINLP) problem of service migration and resource allocation into two sub-problems. Next, we design a new actor-critic-based asynchronous-update deep reinforcement learning method to handle service migration, where the delayed-update actor makes migration decisions and the one-step-update critic evaluates the decisions to guide the policy update. Notably, we theoretically derive the optimal resource allocation with convex optimization for each MEC server, thereby further improving system performance. Using the real-world datasets of vehicle trajectories and testbed, extensive experiments are conducted to verify the effectiveness of the proposed SR-CL. Compared to benchmark methods, the SR-CL achieves superior convergence and delay performance under various scenarios. © 2025 IEEE.

关键词： Convex optimization

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Automatic Deep Active Contour Model Based on Local Image Characteristics

Automatic Deep Active Contour Model Based on Local Image Cha...

引用

IEEE International Conference on Systems, Man and Cybernetics

作者： Haijun You Kai Li Junying Chen Key Laboratory of Big Data and Intelligent Robot (SCUT) Ministry of Education School of Software Engineering South China University of Technology Guangzhou China Department of Ultrasound Third Affiliated Hospital of Sun Yat-sen University Guangzhou China

In recent years, convolutional neural networks have made remarkable achievements in medical image segmentation. Unclear margins and fuzzy boundary regions are formed surrounding the thyroid gland area under the influence of artifacts and speckles, which increases the difficulty of thyroid ultrasound image segmentation. However, building an effective CNN model usually requires massive computing resources, long training time, and large amounts of carefully labeled data. In this work, we develop a fast, compact, accurate and robust image segmentation model for automatic thyroid segmentation in medical ultrasound images. We propose an automatic deep active contour (DAC) model based on local image characteristics, which utilizes the deep neural network model to obtain the initial contour and constructs external energy items based on the local image characteristics of contour points. Compared with the deep neural network model, the DAC model requires less training data, and the segmentation performance of the DAC model on a small dataset can reach that of the deep neural network model on a larger dataset. The proposed DAC model can be used for automatic thyroid segmentation in medical ultrasound images, which does not require massive computing resources, long training time, and large amounts of carefully labeled data.

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