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Scientific data Lake for High Luminosity LHC project and other data-intensive particle and astro-particle physics experiments

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Journal of Physics: Conference Series 2020年第1期1690卷

作者： A Alekseev A Kiryanov A Klimentov T Korchuganova V Mitsyn D Oleynik A Smirnov S Smirnov A Zarochentsev Compiler Technology Department Ivannikov Institute for System Programming of the RAS Moscow 109004 Russia Cloud technologies and Big Data analytics laboratory Plekhanov Russian University of Economics Moscow 117997 Russia ATLAS group Universidad Andres Bello Santiago 7550196 Chile Department of computing resources and technologies NRC 'Kurchatov Institute' - PNPI 188300 Gatchina Russia Physics Department Brookhaven National Laboratory Upton NY 11973 USA Laboratory of Information Technologies Joint Institute for Nuclear Research Dubna 141980 Russia Institute of Nuclear Physics and Engineering National Research Nuclear University MEPhI Moscow 115409 Russia Laboratory of Ultra-High Energy Physics Saint Petersburg State University Saint Petersburg 198504 Russia

The next phase of LHC Operations – High Luminosity LHC (HL-LHC), which is aimed at ten-fold increase in the luminosity of proton-proton collisions at the energy of 14 TeV, is expected to start operation in 2027-2028 and will deliver an unprecedented scientific data volume of multi-exabyte scale. This amount of data has to be stored and the corresponding storage system should ensure fast and reliable data delivery for processing by scientific groups distributed all over the world. The present LHC computing and data processing model will not be able to provide the required infrastructure growth even taking into account the expected hardware technology evolution. To address this challenge the new state-of-the-art computing infrastructure technologies are now being developed and are presented here. The possibilities of application of the HL-LHC distributed data handling technique for other particle and astro-particle physics experiments dealing with large-scale data volumes like DUNE, LSST, Belle-II, JUNO, SKAO etc. are also discussed.

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Model Pruning-enabled Federated Split Learning for Resource-constrained Devices in Artificial Intelligence Empowered Edge computing Environment

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ACM Transactions on Sensor Networks 1000年

作者： Yongzhe Jia Bowen Liu Xuyun Zhang Fei Dai Arif Khan Lianyong Qi Wanchun Dou State Key Laboratory for Novel Software Technology Department of Computer Science and Technology Nanjing University Nanjing China Department of Computing Macquarie University Sydney Australia College of Big Data and Intelligent Engineering Southwest Forestry University Kunming China M3S Empirical Software Engineering Research Unit University of Oulu Oulu Finland College of Computer Science and Technology China University of Petroleum East China - Qingdao Campus Qingdao China

Distributed Collaborative Machine Learning (DCML) has emerged in artificial intelligence-empowered edge computing environments, such as the Industrial Internet of Things (IIoT), to process tremendous data generated by smart devices. However, parallel DCML frameworks require resource-constrained devices to update the entire Deep Neural Network (DNN) models and are vulnerable to reconstruction attacks. Concurrently, the serial DCML frameworks suffer from training efficiency problems due to their serial training nature. In this paper, we propose a Model Pruning-enabled Federated Split Learning framework (MP-FSL) to reduce resource consumption with a secure and efficient training scheme. Specifically, MP-FSL compresses DNN models by adaptive channel pruning and splits each compressed model into two parts that are assigned to the client and the server. Meanwhile, MP-FSL adopts a novel aggregation algorithm to aggregate the pruned heterogeneous models. We implement MP-FSL with a real FL platform to evaluate its performance. The experimental results show that MP-FSL outperforms the state-of-the-art frameworks in model accuracy by up to 1.35%, while concurrently reducing storage and computational resource consumption by up to 32.2% and 26.73%, respectively. These results demonstrate that MP-FSL is a comprehensive solution to the challenges faced by DCML, with superior performance in both reduced resource consumption and enhanced model performance.

关键词： Federated learning split learning model pruning edge computing

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An integrated cyberGIS and machine learning framework for fine-scale prediction of Urban Heat Island using satellite remote sensing and urban sensor network data

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Urban informatics 2022年第1期1卷 6页

作者： Fangzheng Lyu Shaohua Wang Su Yeon Han Charlie Catlett Shaowen Wang cyberGIS Center for Advanced Digital and Spatial Studies University of Illinois at Urbana-Champaign Urbana IL USA. Department of Geography and Geographic Information Science University of Illinois at Urbana-Champaign Urbana IL USA. Key Laboratory of Digital Earth Science Aerospace Information Research Institute Chinese Academy of Sciences Beijing 100094 China. International Research Center of Big Data for Sustainable Development Goals Beijing 100094 China. Computing Environment and Life Sciences Argonne National Laboratory Chicago IL USA.

Due to climate change and rapid urbanization, Urban Heat Island (UHI), featuring significantly higher temperature in metropolitan areas than surrounding areas, has caused negative impacts on urban communities. Temporal granularity is often limited in UHI studies based on satellite remote sensing data that typically has multi-day frequency coverage of a particular urban area. This low temporal frequency has restricted the development of models for predicting UHI. To resolve this limitation, this study has developed a cyber-based geographic information science and systems (cyberGIS) framework encompassing multiple machine learning models for predicting UHI with high-frequency urban sensor network data combined with remote sensing data focused on Chicago, Illinois, from 2018 to 2020. Enabled by rapid advances in urban sensor network technologies and high-performance computing, this framework is designed to predict UHI in Chicago with fine spatiotemporal granularity based on environmental data collected with the Array of Things (AoT) urban sensor network and Landsat-8 remote sensing imagery. Our computational experiments revealed that a random forest regression (RFR) model outperforms other models with the prediction accuracy of 0.45 degree Celsius in 2020 and 0.8 degree Celsius in 2018 and 2019 with mean absolute error as the evaluation metric. Humidity, distance to geographic center, and PM concentration are identified as important factors contributing to the model performance. Furthermore, we estimate UHI in Chicago with 10-min temporal frequency and 1-km spatial resolution on the hottest day in 2018. It is demonstrated that the RFR model can accurately predict UHI at fine spatiotemporal scales with high-frequency urban sensor network data integrated with satellite remote sensing data.

关键词： Machine learning Remote sensing Urban Heat Island Urban sensor network cyberGIS

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Comparative analysis of SIMILAR to RCD ONE(SRO) family from tetraploid cotton species and their diploid progenitors depict their significance in cotton growth and development

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Journal of Cotton Research 2024年第4期 438页

作者： SHABAN Muhammad TABASSUM Riaz RANA Iqrar Ahmad ATIF Rana Muhammad AZMAT Muhammad Abubakkar IQBAL Zubair MAJEED Sajid AZHAR Muhammad Tehseen Department of Plant Breeding and Genetics University of Agriculture Faisalabad Sub-Campus Burewala Department of Chemistry and Biochemistry University of AgricultureFaisalabad Centre of Agricultural Biochemistry and Biotechnology University of AgricultureFaisalabad Department of Plant Breeding and Genetics University of AgricultureFaisalabad Precision Agriculture and Analytics Lab National Centre in Big Data and Cloud Computing Centre for Advanced Studies in Agriculture and Food Security University of Agriculture Faisalabad Department of Plant Pathology University of California State Key Laboratory of Cotton Biology Institute of Cotton ResearchChinese Academy of Agricultural Sciences Federal Seed Certification and Registration Department Ministry of National Food Security and Research School of Agriculture Sciences Zhengzhou University

Background SRO(Similar to RCD1) genes family is largely recognized for their importance in the growth,development,and in responding to environmental ***,genome-wide identification and functional characterization of SRO genes from cotton species have not been reported so *** A total of 36 SRO genes were identified from four cotton *** analysis divided these genes into three groups with distinct *** and chromosomal distribution analysis indicated uneven distribution of GaSRO,GrSRO,GhSRO,and GbSRO genes on A2,D5 genomes,Gh-At,Gh-Dt,Gb-At,and Gb-Dt subgenomes,*** duplication analysis revealed the presence of six duplicated gene pairs among GhSRO *** promoter analysis,several elements responsive to the growth,development and hormones were found in GhSRO genes,implying gene induction during cotton growth and *** miRNAs responsive to plant growth and abiotic stress were predicted to target12 GhSRO ***-specific expression profiling demonstrated the roles of GhSRO genes in one or more *** addition,specific expression pattern of some GhSRO genes during ovule development depicted their involvement in these developmental *** The data presented in this report laid a foundation for understanding the classification and functions of SRO genes in cotton.

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Publisher Correction: A Fast and Refined Cancer Regions Segmentation Framework in Whole-slide Breast Pathological Images

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Scientific reports 2020年第1期10卷 8591页

作者： Zichao Guo Hong Liu Haomiao Ni Xiangdong Wang Mingming Su Wei Guo Kuansong Wang Taijiao Jiang Yueliang Qian Beijing Key Laboratory of Mobile Computing and Pervasive Device Institute of Computing Technology Chinese Academy of Sciences Beijing 100190 China. Beijing Key Laboratory of Mobile Computing and Pervasive Device Institute of Computing Technology Chinese Academy of Sciences Beijing 100190 China. hliu@***. Research Center for Big Data of Biomedical Sciences Institute of Basic Medical Sciences Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100005 China. Suzhou Institute of Systems Medicine Suzhou 215123 China. Graduate School of Peking Union Medical College Beijing 100005 China. Department of Pathology Xiangya Hospital Central South University Changsha Hunan 410013 China. Department of Pathology School of Basic Medical Sciences Central South University Changsha Hunan 410013 China. Department of Pathology Xiangya Hospital Central South University Changsha Hunan 410013 China. ***@***. Department of Pathology School of Basic Medical Sciences Central South University Changsha Hunan 410013 China. ***@***. Research Center for Big Data of Biomedical Sciences Institute of Basic Medical Sciences Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100005 China. taijiao@***. Suzhou Institute of Systems Medicine Suzhou 215123 China. taijiao@***.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Erratum: “Influence of heavy metal materials on magnetic properties of Pt/Co/heavy metal tri-layered structures” [Appl. Phys. Lett. 110, 012405 (2017)]

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Applied Physics Letters 2017年第10期110卷

作者： Boyu Zhang Anni Cao Junfeng Qiao Minghong Tang Kaihua Cao Xiaoxuan Zhao Sylvain Eimer Zhizhong Si Na Lei Zhaohao Wang Xiaoyang Lin Zongzhi Zhang Mingzhong Wu Weisheng Zhao 1Fert Beijing Research Institute Beihang University Beijing 100191 China 2Beijing Advanced Innovation Center for Big Data and Brain Computing (BDBC) Beihang University Beijing 100191 China 3School of Electronic and Information Engineering Beihang University Beijing 100191 China 4Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education) Department of Optical Science and Engineering Fudan University Shanghai 200433 China 5Department of Physics Colorado State University Fort Collins Colorado 80523 USA

The following errors appeared in the above article.1

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Correction: RPTOR blockade suppresses brain metastases of NSCLC by interfering the ceramide metabolism via hijacking YY1 binding

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Journal of experimental & clinical cancer research : CR 2024年第1期43卷 37页

作者： Ying Lin Yun Wu Qiangzu Zhang Xunwei Tu Sufang Chen Junfan Pan Nengluan Xu Ming Lin Peiwei She Gang Niu Yusheng Chen Hongru Li Department of Respiratory and Critical Care Medicine Shengli Clinical Medical College Fujian Medical University Fujian Provincial Hospital Fuzhou 350001 Fujian China. Department of General Practice Medicine Fujian Provincial Hospital Fuzhou 350001 China. The High Performance Computing Research Center Institute of Computing Technology Chinese Academy of Sciences Beijing 100095 China. The Centre for Experimental Research in Clinical Medicine Fujian Provincial Hospital Fuzhou 350001 Fujian China. The High Performance Computing Research Center Institute of Computing Technology Chinese Academy of Sciences Beijing 100095 China. g.niu@***. Department of Respiratory and Critical Care Medicine Shengli Clinical Medical College Fujian Medical University Fujian Provincial Hospital Fuzhou 350001 Fujian China. cysktz@***. Department of Respiratory and Critical Care Medicine Shengli Clinical Medical College Fujian Medical University Fujian Provincial Hospital Fuzhou 350001 Fujian China. muzi131122@***. Fujian Provincial Key Laboratory of Medical Big Data Engineering Fujian Provincial Hospital Shengli Clinical College of Fujian Medical University Fuzhou 350001 Fujian China. muzi131122@***.

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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (vol 50, pg 1412, 2018)

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NATURE GENETICS 2018年第12期50卷 1755-1755页

作者： Evangelou, Evangelos Warren, Helen R. Mosen-Ansorena, David Mifsud, Borbala Pazoki, Raha Gao, He Ntritsos, Georgios Dimou, Niki Cabrera, Claudia P. Karaman, Ibrahim Fu Liang Ng Evangelou, Marina Witkowska, Katarzyna Tzanis, Evan Hellwege, Jacklyn N. Giri, Ayush Edwards, Digna R. Velez Sun, Yan V. Cho, Kelly Gaziano, J. Michael Wilson, Peter W. F. Tsao, Philip S. Kovesdy, Csaba P. Esko, Tonu Magi, Reedik Milani, Lili Almgren, Peter Boutin, Thibaud Debette, Stephanie Ding, Jun Giulianini, Franco Holliday, Elizabeth G. Jackson, Anne U. Li-Gao, Ruifang Lin, Wei-Yu Luan, Jian'an Mangino, Massimo Oldmeadow, Christopher Prins, Bram Peter Qian, Yong Sargurupremraj, Muralidharan Shah, Nabi Surendran, Praveen Theriault, Sebastien Verweij, Niek Willems, Sara M. Zhao, Jing-Hua Amouyel, Philippe Connell, John de Mutsert, Renee Doney, Alex S. F. Farrall, Martin Menni, Cristina Morris, Andrew D. Noordam, Raymond Pare, Guillaume Poulter, Neil R. Shields, Denis C. Stanton, Alice Thom, Simon Abecasis, Goncalo Amin, Najaf Arking, Dan E. Ayers, Kristin L. Barbieri, Caterina M. Batini, Chiara Bis, Joshua C. Blake, Tineka Bochud, Murielle Boehnke, Michael Boerwinkle, Eric Boomsma, Dorret I. Bottinger, Erwin P. Braund, Peter S. Brumat, Marco Campbell, Archie Campbell, Harry Chakravarti, Aravinda Chambers, John C. Chauhan, Ganesh Ciullo, Marina Cocca, Massimiliano Collins, Francis Cordell, Heather J. Davies, Gail de Borst, Martin H. de Geus, Eco J. Deary, Ian J. Deelen, Joris Del Greco, Fabiola M. Demirkale, Cumhur Yusuf Dorr, Marcus Ehret, Georg B. Elosua, Roberto Enroth, Stefan Erzurumluoglu, A. Mesut Ferreira, Teresa Franberg, Mattias Franco, Oscar H. Gandin, Ilaria Gasparini, Paolo Giedraitis, Vilmantas Gieger, Christian Girotto, Giorgia Goel, Anuj Gow, Alan J. Gudnason, Vilmundur Guo, Xiuqing Gyllensten, Ulf Hamsten, Anders Harris, Tamara B. Harris, Sarah E. Hartman, Catharina A. Havulinna, Aki S. Hicks, Andrew A. Hofer, Edith Hofman, Albert Hottenga, Jouke-Jan Huffman, Jennifer E. Hwang, Shih-Jen Ingelsson, Erik James, Alan Jansen Department of Epidemiology and Biostatistics Imperial College London London UK. Department of Hygiene and Epidemiology University of Ioannina Medical School Ioannina Greece. William Harvey Research Institute Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK. National Institute for Health Research Barts Cardiovascular Biomedical Research Center Queen Mary University of London London UK. MRC-PHE Centre for Environment and Health Imperial College London London UK. Department of Mathematics Imperial College London London UK. Division of Epidemiology Department of Medicine Institute for Medicine and Public Health Vanderbilt Genetics Institute Vanderbilt University Medical Center Tennessee Valley Healthcare System (626)/Vanderbilt University Nashville TN USA. Vanderbilt Genetics Institute Vanderbilt Epidemiology Center Department of Obstetrics and Gynecology Vanderbilt University Medical Center Tennessee Valley Health Systems VA Nashville TN USA. Department of Epidemiology Emory University Rollins School of Public Health Atlanta GA USA. Department of Biomedical Informatics Emory University School of Medicine Atlanta GA USA. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC) VA Boston Healthcare System Boston MA USA. Division of Aging Department of Medicine Brigham and Women's Hospital Department of Medicine Harvard Medical School Boston MA USA. Atlanta VAMC and Emory Clinical Cardiovascular Research Institute Atlanta GA USA. VA Palo Alto Health Care System Division of Cardiovascular Medicine Stanford University School of Medicine Stanford CA USA. Nephrology Section Memphis VA Medical Center and University of Tennessee Health Science Center Memphis TN USA. Estonian Genome Center University of Tartu Tartu Estonia. Program in Medical and Population Genetics Broad Institute of Harvard and MIT Cambridge MA USA. Department Clinical Sciences Malmö Lund University Malmö Sweden. MRC

High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1 million people of European ancestry. We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also highlight shared genetic architecture between blood pressure and lifestyle exposures. Our findings identify new biological pathways for blood pressure regulation with potential for improved cardiovascular disease prevention in the future.

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