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A deep learning system for predicting time to progression of diabetic retinopathy

NATURE MEDICINE 2024年第2期30卷 358-359页

作者： [Anonymous] Shanghai Belt and Road International Joint Laboratory for Intelligent Prevention and Treatment of Metabolic Disorders Department of Computer Science and Engineering School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Department of Endocrinology and Metabolism Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai Diabetes Institute Shanghai Clinical Center for Diabetes Shanghai China MOE Key Laboratory of AI School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Shanghai China Department of Ophthalmology Huadong Sanatorium Wuxi China Department of Ophthalmology Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China Department of Ophthalmology and Visual Sciences The Chinese University of Hong Kong Hong Kong China Singapore Eye Research Institute Singapore National Eye Centre Singapore Singapore Department of Computer Science and Engineering The Hong Kong University of Science and Technology Hong Kong China Department of Chemical and Biological Engineering The Hong Kong University of Science and Technology Hong Kong China State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-sen University Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science Guangzhou China Department of Ophthalmology Peking Union Medical College Hospital Peking Union Medical College Chinese Academy of Medical Sciences Beijing China Medical Records and Statistics Office Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China Department of Geriatrics Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China National Engineering Research Center for Big Data Technology and System Services Computing Technology and System Lab Cluster and Grid Computing Lab School of Computer Science and Tech

We developed and validated a deep learning system (termed DeepDR Plus) in a diverse, multiethnic, multi-country dataset to predict personalized risk and time to progression of diabetic retinopathy. We show that DeepDR Plus can be integrated into the clinical workflow to promote individualized intervention strategies for the management of diabetic retinopathy.

关键词： Diabetes complications Machine learning Predictive markers

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Source Code Summarization in the Era of Large Language Models

arXiv

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arXiv 2024年

作者： Sun, Weisong Miao, Yun Li, Yuekang Zhang, Hongyu Fang, Chunrong Liu, Yi Deng, Gelei Liu, Yang Chen, Zhenyu State Key Laboratory for Novel Software Technology Nanjing University Nanjing China College of Computing and Data Science Nanyang Technological University Singapore Singapore School of Computer Science and Engineering University of New South Wales Sidney Australia School of Big Data and Software Engineering Chongqing University Chongqing China

To support software developers in understanding and maintaining programs, various automatic (source) code summarization techniques have been proposed to generate a concise natural language summary (i.e., comment) for a given code snippet. Recently, the emergence of large language models (LLMs) has led to a great boost in the performance of code-related tasks. In this paper, we undertake a systematic and comprehensive study on code summarization in the era of LLMs, which covers multiple aspects involved in the workflow of LLM-based code summarization. Specifically, we begin by examining prevalent automated evaluation methods for assessing the quality of summaries generated by LLMs and find that the results of the GPT-4 evaluation method are most closely aligned with human evaluation. Then, we explore the effectiveness of five prompting techniques (zero-shot, few-shot, chain-of-thought, critique, and expert) in adapting LLMs to code summarization tasks. Contrary to expectations, advanced prompting techniques may not outperform simple zero-shot prompting. Next, we investigate the impact of LLMs’ model settings (including top_p and temperature parameters) on the quality of generated summaries. We find the impact of the two parameters on summary quality varies by the base LLM and programming language, but their impacts are similar. Moreover, we canvass LLMs’ abilities to summarize code snippets in distinct types of programming languages. The results reveal that LLMs perform suboptimally when summarizing code written in logic programming languages compared to other language types (e.g., procedural and object-oriented programming languages). Finally, we unexpectedly find that CodeLlama-Instruct with 7B parameters can outperform advanced GPT-4 in generating summaries describing code implementation details and asserting code properties. We hope that our findings can provide a comprehensive understanding of code summarization in the era of *** Codes 68-04 Copyright © 202

关键词： Quality control

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arXiv

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arXiv 2022年

作者： Liu, Bin Papadopoulos, Dimitrios Malliaros, Fragkiskos D. Tsoumakas, Grigorios Papadopoulos, Apostolos N. Key Laboratory of Data Engineering and Visual Computing Chongqing University of Posts and Telecommunications Chongqing400065 China School of Informatics Aristotle University of Thessaloniki Thessaloniki54124 Greece Gif-sur-Yvette91190 France

The discovery of drug-target interactions (DTIs) is a very promising area of research with great potential. The accurate identification of reliable interactions among drugs and proteins via computational methods, which typically leverage heterogeneous information retrieved from diverse data sources, can boost the development of effective pharmaceuticals. Although random walk and matrix factorization techniques are widely used in DTI prediction, they have several limitations. Random walk-based embedding generation is usually conducted in an unsupervised manner, while the linear similarity combination in matrix factorization distorts individual insights offered by different views. To tackle these issues, we take a multi-layered network approach to handle diverse drug and target similarities, and propose a novel optimization framework, called Multiple similarity DeepWalk-based Matrix Factorization (MDMF), for DTI prediction. The framework unifies embedding generation and interaction prediction, learning vector representations of drugs and targets that not only retain higher-order proximity across all hyper-layers and layer-specific local invariance, but also approximate the interactions with their inner product. Furthermore, we develop an ensemble method (MDMF2A) that integrates two instantiations of the MDMF model, optimizing the area under the precision-recall curve (AUPR) and the area under the receiver operating characteristic curve (AUC) respectively. The empirical study on real-world DTI datasets shows that our method achieves statistically significant improvement over current state-of-the-art approaches in four different settings. Moreover, the validation of highly ranked non-interacting pairs also demonstrates the potential of MDMF2A to discover novel DTIs. Copyright © 2022, The Authors. All rights reserved.

关键词： Forecasting

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Causal-IQA: Towards the Generalization of Image Quality Assessment Based on Causal Inference 41

Causal-IQA: Towards the Generalization of Image Quality Asse...

引用

41st International Conference on Machine Learning, ICML 2024

作者： Zhong, Yan Wu, Xingyu Zhang, Li Yang, Chenxi Jiang, Tingting School of Mathematical Sciences Peking University Beijing China National Engineering Research Center of Visual Technology National Key Laboratory for Multimedia Information Processing School of Computer Science Peking University Beijing China Department of Computing The Hong Kong Polytechnic University Hong Kong Hefei Institute of Physical Science Chinese Academy of Sciences University of Science and Technology of China Hefei China National Biomedical Imaging Center Peking University Beijing China

Due to the high cost of Image Quality Assessment (IQA) datasets, achieving robust generalization remains challenging for prevalent deep learning-based IQA *** address this, this paper proposes a novel end-to-end blind IQA method: ***, we first analyze the causal mechanisms in IQA tasks and construct a causal graph to understand the interplay and confounding effects between distortion types, image contents, and subjective human ***, through shifting the focus from correlations to causality, Causal-IQA aims to improve the estimation accuracy of image quality scores by mitigating the confounding effects using a causality-based optimization *** optimization strategy is implemented on the sample subsets constructed by a Counterfactual Division process based on the Backdoor *** experiments illustrate the superiority of Causal-IQA. Copyright 2024 by the author(s)

关键词： Image correlation

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Rethinking the visual cues in audio-visual speaker extraction

arXiv

引用

arXiv 2023年

作者： Li, Junjie Ge, Meng Pan, Zexu Cao, Rui Wang, Longbiao Dang, Jianwu Zhang, Shiliang Tianjin Key Laboratory of Cognitive Computing and Application College of Intelligence and Computing Tianjin University Tianjin China Department of Electrical and Computer Engineering National University of Singapore Singapore Institute of Data Science National University of Singapore Singapore Shenzhen Research Institute of Big Data Shenzhen China

The Audio-visual Speaker Extraction (AVSE) algorithm employs parallel video recording to leverage two visual cues, namely speaker identity and synchronization, to enhance performance compared to audio-only algorithms. However, the visual front-end in AVSE is often derived from a pre-trained model or end-to-end trained, making it unclear which visual cue contributes more to the speaker extraction performance. This raises the question of how to better utilize visual cues. To address this issue, we propose two training strategies that decouple the learning of the two visual cues. Our experimental results demonstrate that both visual cues are useful, with the synchronization cue having a higher impact. We introduce a more explainable model, the Decoupled Audio-visual Speaker Extraction (DAVSE) model, which leverages both visual cues. Copyright © 2023, The Authors. All rights reserved.

关键词： Extraction

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First-Order Meta-Learning in Node Classification with Graph Convolutional Network 4

First-Order Meta-Learning in Node Classification with Graph ...

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4th International Conference on Artificial Intelligence and Big data, ICAIBD 2021

作者： Cao, Jing Xu, Yi Song, Xuening School of Information and Software Engineering University of Electronic Science and Technology of China China Trusted Cloud Computing and Big Data Key Laboratory of Sichuan Province Chengdu China

ISBN: (纸本)9780738131702

In recent years, research on graph representation learning within graph neural networks has made great progress. Among them, graph convolutional neural networks (GCN), which is based on spectral domain, have drawn great attention and become one of the mainstream graph embedding approaches. However, few-shot learning on graphs has little related work, as we know. Toward this problem, we propose a meta-learning method on graphs, FOML-GCN (First order meta-learning on GCN), aimed to be applied in various kinds of models of graph convolutional networks. As many common approaches in meta-learning, FOML-GCN involves two phases, meta-training and meta-testing. By learning the potential Knowledge from a small number of samples in existing classes during meta-training, our method enhances the ability in node classification of the base model by training within new few data that only appear in the meta-testing step. The experiment on two benchmark datasets shows that our FOML-GCN performs better than base GCN and other models of graph network in few-shot node classification tasks. © 2021 IEEE.

关键词： Graph neural networks

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A Software Diversity-Based Lab in Operating System for Cyber Security Students 3

A Software Diversity-Based Lab in Operating System for Cyber...

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3rd IEEE International Conference on Computer Science and Educational Informatization, CSEI 2021

作者： Wang, Junchao Pang, Jianmin Shan, Zheng Wei, Jin Yao, Jinyang Liu, Fudong State Key Laboratory of Mathematical Engineering and Advanced Computing Zheng Zhou China School of Computer Science Data Arena Institute Fudan University Zheng Zhou China

ISBN: (纸本)9781728184739

The course of operating system's labs usually fall behind the state of art technology. In this paper, we propose a Software Diversity-Assisted Defense (SDAD) lab based on software diversity, mainly targeting for students majoring in cyber security and computer science. This lab is consisted of multiple modules and covers most of the important concepts and principles in operating systems. Thus, the knowledge learned from the theoretical course will be deepened with the lab. For students majoring in cyber security, they can learn this new software diversity-based defense technology and understand how an exploit works from the attacker's side. The experiment is also quite stretchable, which can fit all level students. © 2021 IEEE.

关键词： Students

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An Enhanced Deep Reinforcement Learning-Based Global Router for VLSI Design

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Wireless Communications and Mobile computing 2023年第1期2023卷

作者： Xu, Saijuan Yang, Liliang Liu, Genggeng Department of Information Engineering Fujian Business University Fuzhou China College of Computer and Data Science Fuzhou University Fuzhou China Key Laboratory of Network Computing and Intelligent Information Processing Fuzhou University Fuzhou China

Global routing is a crucial step in the design of Very Large-Scale Integration (VLSI) circuits. However, most of the existing methods are heuristic algorithms, which cannot conjointly optimize the subproblems of global routing, resulting in congestion and overflow. In response to this challenge, an enhanced Deep Reinforcement Learning- (DRL-) based global router has been proposed, which comprises the following effective strategies. First, to avoid the overestimation problem generated by Q-learning, the proposed global router adopts the Double Deep Q-Network (DDQN) model. The DDQN-based global router has better performance in wire length optimization and convergence. Second, to avoid the agent from learning redundant information, an action elimination method is added to the action selection part, which significantly enhances the convergence performance of the training process. Third, to avoid the unfair allocation problem of routing resources in serial training, concurrent training is proposed to enhance the routability. Fourth, to reduce wire length and disperse routing resources, a new reward function is proposed to guide the agent to learn better routing solutions regarding wire length and congestion standard deviation. Experimental results demonstrate that the proposed algorithm outperforms others in several important performance metrics, including wire length, convergence performance, routability, and congestion standard deviation. In conclusion, the proposed enhanced DRL-based global router is a promising approach for solving the global routing problem in VLSI design, which can achieve superior performance compared to the heuristic method and DRL-based global router. © 2023 Saijuan Xu et al.

关键词： Reinforcement learning

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$\mathbf{A^{3}}$A3-CodGen: A Repository-Level Code Generation Framework for Code Reuse With Local-Aware, Global-Aware, and Third-Party-Library-Aware

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IEEE Transactions on Software engineering 2024年第12期50卷 3369-3384页

作者： Dianshu Liao Shidong Pan Xiaoyu Sun Xiaoxue Ren Qing Huang Zhenchang Xing Huan Jin Qinying Li School of Computing Australian National University Canberra ACT Australia CSIRO’s Data61 Sydney NSW Australia State Key Laboratory of Blockchain and Data Security Zhejiang University Hangzhou China Hangzhou High-Tech Zone (Binjiang) Institute of Blockchain and Data Security Hangzhou China School of Computer Information Engineering Jiangxi Normal University Jiangxi China Jiangxi University of Technology Jiangxi China

LLM-based code generation tools are essential to help developers in the software development process. Existing tools often disconnect with the working context, i.e., the code repository, causing the generated code to be not similar to human developers. In this paper, we propose a novel code generation framework, dubbed $A^{3}$ -CodGen, to harness information within the code repository to generate code with fewer potential logical errors, code redundancy, and library-induced compatibility issues. We identify three types of representative information for the code repository: local-aware information from the current code file, global-aware information from other code files, and third-party-library information. Results demonstrate that by adopting the $A^{3}$ -CodGen framework, we successfully extract, fuse, and feed code repository information into the LLM, generating more accurate, efficient, and highly reusable code. The effectiveness of our framework is further underscored by generating code with a higher reuse rate, compared to human developers. This research contributes significantly to the field of code generation, providing developers with a more powerful tool to address the evolving demands in software development in practice.

关键词： Codes Libraries Software development management data mining Benchmark testing Transformers Software engineering Context modeling Chatbots Australia

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Last-X-Generation Archiving Strategy for Multi-Objective Evolutionary Algorithms

Last-X-Generation Archiving Strategy for Multi-Objective Evo...

引用

Congress on Evolutionary Computation

作者： Tianye Shu Yang Nan Ke Shang Hisao Ishibuchi Department of Computer Science and Engineering Guangdong Provincial Key Laboratory of Brain-inspired Intelligent Computation Southern University of Science and Technology Shenzhen China Southern University of Science and Technology Shenzhen China National Engineering Laboratory for Big Data System Computing Technology Shenzhen University Shenzhen China

ISBN: (数字)9798350308365

ISBN: (纸本)9798350308372

For evolutionary multi-objective optimization algorithms (EMOAs), an external archive can be utilized for saving good solutions found throughout the evolutionary process. Recent studies showed that a solution set selected from an external archive is usually superior to the final population. That is, the incorporation of an external archive improves the performance of EMOAs. However, the computation time for maintaining an external archive is long, especially when the archive size is large. To solve this issue, a simple archiving strategy is to save all solutions generated in the last several generations. In this paper, we examine this archiving strategy for three representative EMOAs on artificial test problems (Minus-DTLZ and WFG) and real-world problems (RE). Our results show that archiving the last several generations clearly improves the performance of EMOAs without severely increasing the computation time.

关键词： Costs Sociology Evolutionary computation Statistics Optimization Standards

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