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2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024

作者： Hu, Min Xu, Lingxiang Liu, Lei Wang, Xiaohua Li, Hongbo Yang, Jiaoyun Hefei University of Technology Anhui Province Key Laboratory of Affective Computing and Advanced Intelligent Machine Hefei China Hefei University of Technology National Smart Eldercare International Science and Technology Cooperation Base Hefei China Hefei University of Technology Intelligent Interconnected Systems Laboratory of Anhui Province Hefei China

ISBN: (纸本)9798350386226

Artificial intelligence methods offer objectivity and convenience in automatic depression detection, however, current research often neglects the critical role of facial landmarks. This oversight results in insufficient spatial structure information and a lack of detailed local representation, which fails to capture the nuanced semantic information crucial for identifying depression-related clues. To address these issues, we introduce a novel dual-branch network model comprising the Landmark-Image-Landmark Net (LIL Net) and the Global Context Vision Transformer Net (GCVit Net). Through a dual-stream, multiscale, and cross-fusion strategy, LIL Net is designed to extract original facial image features alongside landmark features, prioritizing the detailed semantic information of potential depression clues. LIL Net employs an innovative LIL Attention approach to jointly learn multiscale features from facial landmarks and images, thereby enhancing the model's ability to capture fine-grained depression-related cues. Furthermore, the Multi-scale Feature Fusion (MSFF) module fuses the obtained multiscale features, augmenting the semantic expression of potential depression clues within facial landmarks via attention mechanisms. Meanwhile, the GCVit Net branch network supplements global information by extracting global facial features. Finally, the features from both branches are concatenated to enhance the accuracy of depression degree predictions. Experimental results demonstrate that our model has superior performance in detecting depression compared to existing methods. We release our code at https://***/xlx777/LIL-Net. © 2024 IEEE.

关键词： Artificial intelligence

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Adaptive Neural Tracking Control for Nonlinear Servo System with Unknown Time-Varying Parameters and Uncertainties 42

Adaptive Neural Tracking Control for Nonlinear Servo System ...

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42nd Chinese Control Conference, CCC 2023

作者： Zhang, Faxiang Gao, Guanbin Na, Jing Wu, Jiande Kunming University of Science and Technology Faculty of Mechanical and Electrical Engineering Yunnan International Joint Laboratory of Intelligent Control and Application of Advanced Equipment Kunming650500 China Yunnan University Yunnan Key Laboratory of Intelligent Systems and Computing Kunming650500 China

ISBN: (纸本)9789887581543

This paper solves the neural network (NN) tracking control problem for uncertain nonlinear servo system with time-varying parameters and uncertainties. To address the uncertain nonlinear function with unknown time-varying parameters (i.e., unknown nonlinear spatiotemporal function), the time-varying parameter extraction method is used to separate the time-varying parameters from uncertain nonlinear spatiotemporal function, which yields an unknown state-based boundary function. By the tools of NN and adaptive technology, an adaptive neural tracking controller is designed, which guarantees the uniformly ultimately bounded (UUB) performance of the resulting closed-loop system. The effectiveness of the designed method is verified by simulations. © 2023 Technical Committee on Control Theory, Chinese Association of Automation.

关键词： Servomechanisms

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Text Guided Road Marking Point Cloud Completion

Text Guided Road Marking Point Cloud Completion

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Next Generation data-driven Networks (NGDN), International Conference on

作者： Xu He Qihong Xu Huan Luo College of Computer and Data Science Fuzhou University Fujian Provincial Key Laboratory of Network Computing and Intelligent Information Processing Fuzhou University Fuzhou China

ISBN: (数字)9798350388374

ISBN: (纸本)9798350388381

With the continuous development of intelligent transportation technologies such as autonomous driving and navigation, accurate perception of road markings becomes crucial. However, due to limitations in sensor perspectives and obstacles blocking the view, the scanned point cloud of road markings is often incomplete, potentially leading to erroneous decisions in intelligent transportation systems. Therefore, it becomes imperative to recover complete road markings from these incomplete point clouds. This paper proposes a text-guided road marking completion method, which integrates text information with point cloud data using attention mechanisms. By leveraging text information to guide the network in completing road marking point clouds, the proposed method aims to enhance the perception accuracy and completeness of road markings. Experimental validation on road marking datasets demonstrates the effectiveness and feasibility of the proposed approach.

关键词： Point cloud compression Accuracy Attention mechanisms Navigation Fuses Roads Transportation Diffusion models Robustness Next generation networking

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Protein Structure Prediction:Challenges,Advances,and the Shift of Research Paradigms

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Genomics, Proteomics & Bioinformatics 2023年第5期21卷 913-925页

作者： Bin Huang Lupeng Kong Chao Wang Fusong Ju Qi Zhang Jianwei Zhu Tiansu Gong Haicang Zhang Chungong Yu Wei-Mou Zheng Dongbo Bu Key Laboratory of Intelligent Information Processing Institute of Computing TechnologyChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Changping Laboratory Beijing 102206China Microsoft Research AI4Science Beijing 100080China Huawei Noah’s Ark Lab Wuhan 430206China Zhongke Big Data Academy Zhengzhou 450046China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China

Protein structure prediction is an interdisciplinary research topic that has attracted researchers from multiple fields,including biochemistry,medicine,physics,mathematics,and computer *** researchers adopt various research paradigms to attack the same structure prediction problem:biochemists and physicists attempt to reveal the principles governing protein folding;mathematicians,especially statisticians,usually start from assuming a probability distribution of protein structures given a target sequence and then find the most likely structure,while computer scientists formulate protein structure prediction as an optimization problem-finding the structural conformation with the lowest energy or minimizing the difference between predicted structure and native *** research paradigms fall into the two statistical modeling cultures proposed by Leo Breiman,namely,data modeling and algorithmic ***,we have also witnessed the great success of deep learning in protein structure *** this review,we present a survey of the efforts for protein structure *** compare the research paradigms adopted by researchers from different fields,with an emphasis on the shift of research paradigms in the era of deep *** short,the algorithmic modeling techniques,especially deep neural networks,have considerably improved the accuracy of protein structure prediction;however,theories interpreting the neural networks and knowledge on protein folding are still highly desired.

关键词： Protein folding Protein structure prediction Deep learning Transformer Language model

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A Hierarchical Adaptive Multi-Task Reinforcement Learning Framework for Multiplier Circuit Design 41

A Hierarchical Adaptive Multi-Task Reinforcement Learning Fr...

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41st International Conference on Machine Learning, ICML 2024

作者： Wang, Zhihai Wang, Jie Zuo, Dongsheng Ji, Yunjie Xia, Xilin Ma, Yuzhe Hao, Jianye Yuan, Mingxuan Zhang, Yongdong Wu, Feng CAS Key Laboratory of Technology in GIPAS MoE Key Laboratory of Brain-inspired Intelligent Perception and Cognition University of Science and Technology of China China Microelectronics Thrust Hong Kong University of Science and Technology Guangzhou China Noah's Ark Lab Huawei Technologies China College of Intelligence and Computing Tianjin University China

Multiplier design-which aims to explore a large combinatorial design space to simultaneously optimize multiple conflicting objectives-is a fundamental problem in the integrated circuits industry. Although traditional approaches tackle the multi-objective multiplier optimization problem by manually designed heuristics, reinforcement learning (RL) offers a promising approach to discover high-speed and area-efficient multipliers. However, the existing RL-based methods struggle to find Pareto-optimal circuit designs for all possible preferences, i.e., weights over objectives, in a sample-efficient manner. To address this challenge, we propose a novel hierarchical adaptive (HAVE) multi-task reinforcement learning framework. The hierarchical framework consists of a meta-agent to generate diverse multiplier preferences, and an adaptive multi-task agent to collaboratively optimize multipliers conditioned on the dynamic preferences given by the meta-agent. To the best of our knowledge, HAVE is the first to well approximate Pareto-optimal circuit designs for the entire preference space with high sample efficiency. Experiments on multipliers across a wide range of input widths demonstrate that HAVE significantly Pareto-dominates state-of-the-art approaches, achieving up to 28% larger hypervolume. Moreover, experiments demonstrate that multipliers designed by HAVE can well generalize to large-scale computation-intensive circuits. Copyright 2024 by the author(s)

关键词： Reinforcement learning

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Exploiting Multiple Features for Hash Codes Learning with Semantic-Alignment-Promoting Variational Auto-encoder 12th

Exploiting Multiple Features for Hash Codes Learning with Se...

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12th National CCF Conference on Natural Language Processing and Chinese computing, NLPCC 2023

作者： Chen, Jiayang Su, Qinliang School of Computer Science and Engineering Sun Yat-Sen University Guangzhou China Guangdong Key Laboratory of Big Data Analysis and Processing Guangzhou China Key Laboratory of Machine Intelligence and Advanced Computing Ministry of Education Beijing China

ISBN: (纸本)9783031446924

Semantic hashing is an effective technique to empower information retrieval. Currently, considerable efforts have been dedicated to generating high-quality hash codes by modeling document features using generative models and other approaches. However, most of these methods rely solely on a single type of feature, such as TFIDF features, BERT embeddings, etc. As different types of features have distinct but complementary information of documents, e.g. TFIDF mainly contains the keywords information and BERT focuses on the semantics, hash codes generated solely from either may not capture the full essence of the documents. To overcome this challenge, we propose a semantic-alignment-promoting variational auto-encoder to generate hash codes from multiple document features. Specifically, a VAE-based generative model is first developed to model the multiple features. Then, we propose a semantic-alignment-promoting inference network to estimate the parameters of the variational posterior from multiple features. Additionally, the quality of hash codes is further improved by promoting the semantic alignment between the hash codes of connected documents in a constructed connection graph. The results of extensive experiments on three public datasets demonstrate that our proposed model significantly outperforms current state-of-the-art models. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.

关键词： Semantics

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Interpretable multi-view attention network for drug-drug interaction prediction

Interpretable multi-view attention network for drug-drug int...

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2023 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2023

作者： Lin, Xuan Wen, Qi Yang, Sijie Yu, Zu-Guo Long, Yahui Zeng, Xiangxiang Xiangtan University College of Computer Science China Xiangtan University Key Laboratory of Intelligent Computing and Information Processing of Ministry of Education China Singapore Hunan University College of Information Science and Engineering China

ISBN: (纸本)9798350337488

Drug-drug interaction (DDI) plays an increasingly crucial role in drug discovery. Predicting potential DDI is also essential for clinical research. Given the high cost and risk of wet-lab experiments, in-silico DDI prediction is an alternative choice. Recently, deep learning methods have been developed for DDI prediction. However, most of existing methods focus on feature extraction from either molecular SMILES sequences or drug interactive networks, ignoring the valuable complementary information that can be derived from these two views. In this paper, we propose a novel interpretable Multi-View Attention network (MVA-DDI) for DDI prediction. MVA-DDI can effectively extracts drug representations from different perspectives to improve DDI prediction. Specifically, for a given drug, we design a transformer-based encoder and a graph convolutional networkbased encoder to learn sequence and graph representations from SMILES sequence and molecular graph, respectively. To fully exploit the complementary information between the sequence and molecular views, an attention mechanism is further adopted to adaptively aggregate the sequence and graph representations by taking the importance of different views into accounts, generating the final drug representations. Comparison experiments demonstrated that our MVA-DDI1 model achieved superior performance to state-of-the-art models on DDI prediction. © 2023 IEEE.

关键词： Contrastive learning Drug-drug interaction prediction Interpretable attention network Multi-view learning

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A News Media Bias and Factuality Profiling Framework Assisted by Modeling Correlation

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Computers, Materials & Continua 2024年第11期81卷 3351-3369页

作者： Qi Wang Chenxin Li Chichen Lin Weijian Fan Shuang Feng Yuanzhong Wang School of Computer and Cyber Sciences Communication University of ChinaBeijing100024China State Key Laboratory of Media Convergence and Communication Communication University of ChinaBeijing100024China School of Data Science and Intelligent Media Communication University of ChinaBeijing100024China Beijing 797 Audio Co. Ltd.Beijing100016China

News media profiling is helpful in preventing the spread of fake news at the source and maintaining a good media and news *** previous works only extract features and evaluate media from one dimension independently,ignoring the interconnections between different *** paper proposes a novel news media bias and factuality profiling framework assisted by correlated *** framework models the relationship and interaction between media bias and factuality,utilizing this relationship to assist in the prediction of profiling *** approach extracts features independently while aligning and fusing them through recursive convolu-tion and attention mechanisms,thus harnessing multi-scale interactive information across different dimensions and *** method improves the effectiveness of news media *** results indicate that our proposed framework significantly outperforms existing methods,achieving the best performance in Accuracy and F1 score,improving by at least 1%compared to other *** paper further analyzes and discusses based on the experimental results.

关键词： News media profiling factuality bias correlated features

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CSCL-DTI: Predicting drug-target interaction through cross-view and self-supervised contrastive learning

CSCL-DTI: Predicting drug-target interaction through cross-v...

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2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024

作者： Lin, Xuan Zhang, Xi Yu, Zu-Guo Long, Yahui Zeng, Xiangxiang Yu, Philip S. Xiangtan University College of Computer Science China Xiangtan University Key Laboratory of Intelligent Computing and Information Processing Ministry of Education China Singapore Hunan University College of Information Science and Engineering China University of Illinois Chicago Department of Computer Science United States

ISBN: (纸本)9798350386226

Accurately predicting drug-target interactions (DTI) is a critical step in drug discovery. Existing methods of DTI prediction primarily employ Simplified Molecular-Input Line-Entry System (SMILES) sequences or molecular graphs to learn drug representations. However, the features learned by such single-view approach is prone to incomplete. While some multiview methods that consider the views of both SMILES sequences and molecular graphs have been developed, these methods often fall in short in capturing potential interactions between views. In this work, we propose a novel dual contrastive learning framework CSCL-DTI for DTI prediction. First, we design a contrastive-enhanced cross-view representation learning (CVRL) to learn representations for drugs. In this module, Transformer-based and graph convolutional network (GCN)-based encoders are separately adopted to learn view-specific representations, followed by contrastive learning to enrich the representations by accounting for the potential interplay between local chemical context and topological structure. Second, we combine Transformer with self-supervised contrastive learning (SSCL) to learn representations for targets by modelling protein amino acids sequences. The scheme allows to effectively preserve the intrinsic characteristics of the sequences. Finally, we introduce a bilinear attention network to obtain an integrated representation by adaptively incorporating drug and target representations. Benchmarking experiments on two datasets demonstrated that CSCL-DTI1 outperforms six state-of-the-art methods. © 2024 IEEE.

关键词： Contrastive Learning

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Mitigating Over-Unlearning in Machine Unlearning with Synthetic data Augmentation 24th

Mitigating Over-Unlearning in Machine Unlearning with Synt...

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24th International Conference on Algorithms and Architectures for Parallel Processing, ICA3PP 2024

作者： Wang, Baohai Qu, Youyang Gao, Longxiang Li, Conggai Li, Lin Smith, David Jinan China Shandong Provincial Key Laboratory of Computing Power Internet and Service Computing Shandong Fundamental Research Center for Computer Science Jinan China Data61 Commonwealth Science and Industry Research Organization CanberraVIC Australia College of Business and Law Royal Melbourne Institute of Technology MelbourneVIC Australia

ISBN: (纸本)9789819615445

In machine learning, data privacy and security has become an increasingly growing concern. The introduction of machine unlearning offers the ability to address this issue through the removal of personal and sensitive data from trained models to comply with laws, regulations, and user privacy requirements. However, despite the significant benefits of this technique, performing unlearning operations is only sometimes smooth in practice. When we attempt to remove specific data, the model may over-adjust, resulting in its performance on unlearned data. This phenomenon not only reduces the accuracy of the model on known data but also affects its ability to generalize new data, thus weakening the model’s overall performance. Therefore, in this paper, we analyze the phenomenon of over-unlearning;firstly, we explore how to mitigate the effects of over-unlearning by generating synthetic data to fill in the forgotten parts, using data synthesis-based techniques. Secondly, we combine the data synthesis-based compensation strategy with model fine-tuning to further improve the model’s adaptability and generalization capability by further training the model to accommodate synthetic data. Through comprehensive experimentation, we verify the effectiveness of the proposed data synthesis-based compensation strategy. The experimental results show that the data synthesis-based compensation strategy can effectively mitigate the effects of the over-unlearning phenomenon, as well as maintaining the stability and accuracy of the model after removing specific data. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2025.

关键词： data assimilation

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