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A novel computational approach to predict activity of nuclear export signals

Journal of Computational and Theoretical Nanoscience 2015年第12期12卷 6016-6019页

作者： Chen, Zhihua Zhang, Pan Wu, Tingfang Shi, Xiaolong Wang, Xun Key Laboratory of Image Information Processing and Intelligent Control School of Automation Huazhong University of Science and Technology WuhanHubei430074 China College of Computer and Communication Engineering China University of Petroleum QingdaoShandong266580 China

A nuclear export signal (NES) is a sequence of amino acids, which is a protein localization signal, and contributes to regulate localization of cellular proteins. In recent peering works, activity of NESs were introduced in computational methods, which perform significantly well in identifying unknown NESs even from huge datasets, but suffer from a shortage that only a small number of NESs are associated with experimental verified active scores. In this work, we propose a novel computational method to predict active score of NESs. Specifically, we firstly abstract relevant features to NES activity, and then construct a mathematical model based on principal component analysis (PCA) to find each feature's contribution to activity. In this way, a method to calculate active score of unknown NESs is achieved. In data experiments, it is obtained that our method can achieve accuracy rate 80%. The activity of an unknown NES candidate can give us a preliminary understanding of it, and can be used to identify positive NESs from the negative ones. To the best acknowledge of the authors, this is the first time computational method is proposed to predict NESs' activity. Copyright © 2015 American Scientific Publishers All rights reserved.

关键词： Computational methods

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Generative Adversarial Network-Based Electromagnetic Signal Classification: A Semi- Supervised Learning Framework

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China Communications 2020年第10期17卷 157-169页

作者： Huaji Zhou Licheng Jiao Shilian Zheng Lifeng Yang Weiguo Shen Xiaoniu Yang Key Laboratory of Intelligent Perception and Image Understanding of Ministry of Education School of Artificial IntelligenceXidian UniversityXi'an 710071China Science and Technology on Communication Information Security Control Laboratory Jiaxing 314033China

Generative adversarial network(GAN)has achieved great success in many fields such as computer vision,speech processing,and natural language processing,because of its powerful capabilities for generating realistic *** this paper,we introduce GAN into the field of electromagnetic signal classification(ESC).ESC plays an important role in both military and civilian ***,in many specific scenarios,we can’t obtain enough labeled data,which cause failure of deep learning methods because they are easy to fall into ***,semi-supervised learning(SSL)can leverage the large amount of unlabeled data to enhance the classification performance of classifiers,especially in scenarios with limited amount of labeled *** present an SSL framework by incorporating GAN,which can directly process the raw in-phase and quadrature(IQ)signal *** to the characteristics of the electromagnetic signal,we propose a weighted loss function,leading to an effective classifier to realize the end-to-end classification of the electromagnetic *** validate the proposed method on both public RML2016.04c dataset and real-world Aircraft Communications Addressing and Reporting System(ACARS)signal *** experimental results show that the proposed framework obtains a significant increase in classification accuracy compared with the state-of-the-art studies.

关键词： generative adversarial network semi-supervised learning electromagnetic signal classification end-to-end classification weighted loss function

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3-D reconstruction of blood vessels skeleton based on Neural network

3-D reconstruction of blood vessels skeleton based on Neural...

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13th International Conference on Neural Information processing, ICONIP 2006

作者： Zhiguo, Cao Bo, Peng Institute of Image Processing and Artificial Intelligence Huazhong University of Sci. and Tec. State Key Lab. for Image Processing and Intelligent Control Wuhan 430074 Hubei China

ISBN: (纸本)3540464840

For the 3-D reconstruction of blood vessels skeleton from biplane angiography system, an efficient 3-D reconstruction method based on neural network(NN) is proposed in this paper. First, we find a set of 2-D corresponding points on the vessels' skeleton in the matched image pair. Secondly, NN is utilized to build the relationships between the 3-D points and their projective 2-D points. Thirdly, by feeding the corresponding points we found into the NN, the 3D coordinates of the points on vessels can be obtained. At last we employ B-spline interpolation to improve reconstruction performance. Experiment results demonstrate the efficiency of the new method. © Springer-Verlag Berlin Heidelberg 2006.

关键词： Blood vessels

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Multiobjective optimization using an immunodominance and clonal selection inspired algorithm

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Science in China(Series F) 2008年第8期51卷 1064-1082页

作者： GONG MaoGuo JIAO LiCheng MA WenPing DU HaiFeng Key Laboratory of Intelligent Perception and Image Understanding of Ministry of Education of China Institute of Intelligent Information Processing Xidian University Xi'an 710071 China School of Public and Administration Xi'an Jiaotong University Xi'an 710049 China

Based on the mechanisms of immunodominance and clonal selection theory, we propose a new multiobjective optimization algorithm, immune dominance clonal multiobjective algorithm （IDCMA）. IDCMA is unique in that its fitness values of current dominated individuals are assigned as the values of a custom distance measure, termed as Ab-Ab affinity, between the dominated individuals and one of the nondominated individuals found so far. According to the values of Ab-Ab affinity, all dominated individuals （antibodies） are divided into two kinds, subdominant antibodies and cryptic antibodies. Moreover, local search only applies to the subdominant antibodies, while the cryptic antibodies are redundant and have no function during local search, but they can become subdominant （active） antibodies during the subsequent evolution. Furthermore, a new immune operation, clonal proliferation is provided to enhance local search. Using the clonal proliferation operation, IDCMA reproduces individuals and selects their improved maturated progenies after local search, so single individuals can exploit their surrounding space effectively and the newcomers yield a broader exploration of the search space. The performance comparison of IDCMA with MISA, NSGA-Ⅱ, SPEA, PAES, NSGA, VEGA, NPGA, and HLGA in solving six well-known multiobjective function optimization problems and nine multiobjective 0/1 knapsack problems shows that IDCMA has a good performance in converging to approximate Pareto-optimal fronts with a good distribution.

关键词： multiobjective optimization immunodominance clonal selection artificial immune systems evolutionaryalgorithms

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Research on fuzzy enhancement in the diagnosis of liver tumor from B-mode ultrasound images

Research on fuzzy enhancement in the diagnosis of liver tumo...

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2011 IEEE International conference on intelligent Computation and Bio-Medical Instrumentation, ICBMI 2011

作者： Qiu, Wu Wang, Rui Xiao, Feng Ding, Mingyue School of Life Science and Technololgy Key Laboratory of Image Processing and Intelligent Control of Education Ministry of China Huazhong University of Science and Technology Wuhan Hubei China

ISBN: (纸本)9780769546230

Fuzzy enhancement is applied in computer aided diagnosis of liver cancer from B mode ultrasound images as a pre-processing procedure in this paper. It was evaluated with three classifiers including K means, back propagation neural network and support vector machine using 25 features from first order statistic (FOS), gray-level co-occurrence matrix (GLCM), gray-level run-length matrix (GLRLM), Grey level dependant matrix (GLDM) and LAWS. In the analysis of 166 normal liver tissue, 30 hemangioma and 60 malignant tumor, our method improved the classification accuracy of three classifiers (K means, BP neural network and support machine vector) in distinguishing liver cancer, hemangioma and normal liver cancer from B mode ultrasound images. It is proved that fuzzy enhancement as an efficient preprocessing procedure could be used in the computer aided diagnosis system of liver cancer. © 2011 IEEE.

关键词： Support vector machines

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Semisupervised Transfer Boosting (SS-TrBoosting)

IEEE Transactions on Artificial Intelligence

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IEEE Transactions on Artificial Intelligence 2024年第7期5卷 3431-3444页

作者： Deng, Lingfei Zhao, Changming Du, Zhenbang Xia, Kun Wu, Dongrui Key Laboratory of Image Processing and Intelligent Control Ministry of Education School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan 430074 China and also with Shenzhen Huazhong University of Science and Technology Research Institute Shenzhen 518063 China

Semisupervised domain adaptation (SSDA) aims at training a high-performance model for a target domain using few labeled target data, many unlabeled target data, and plenty of auxiliary data from a source domain. Previous works in SSDA mainly focused on learning transferable representations across domains. However, it is difficult to find a feature space where the source and target domains share the same conditional probability distribution. Additionally, there is no flexible and effective strategy extending existing unsupervised domain adaptation (UDA) approaches to SSDA settings. In order to solve the above two challenges, we propose a novel fine-tuning framework, semisupervised transfer boosting (SS-TrBoosting). Given a well-trained deep learning-based UDA or SSDA model, we use it as the initial model, generate additional base learners by boosting, and then use all of them as an ensemble. More specifically, half of the base learners are generated by supervised domain adaptation, and half by semisupervised learning. Furthermore, for more efficient data transmission and better data privacy protection, we propose a source data generation approach to extend SS-TrBoosting to semisupervised source-free domain adaptation (SS-SFDA). Extensive experiments showed that SS-TrBoosting can be applied to a variety of existing UDA, SSDA, and SFDA approaches to further improve their performance. © 2020 IEEE.

关键词： Supervised learning

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A multiobjective immune clustering ensemble technique applied to unsupervised SAR image segmentation 10

A multiobjective immune clustering ensemble technique applie...

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ACM International Conference on image and Video Retrieval, ACM-CIVR 2010

作者： Liu, Ruochen Zhang, Wei Jiao, Licheng Liu, Fang Key Laboratory of Intelligent Perception and Image Understanding of Ministry of Education of China Institute of Intelligent Information Processing Xidian University Xi'an China

ISBN: (纸本)9781450301176

In the past few years, multiobjective clustering has been one of the most successful techniques in the field of computer vision and data clustering. This paper proposes a novel unsupervised approach for synthetic aperture radar (SAR) image segmentation, namely, multiobjective immune clustering ensemble technique (MICET). The new technique first divides the image into several regions, and a certain number of pixels are picked out from these regions to form the clustering dataset. Second, artificial immune system (AIS) and multiobjective optimization (MOO) are introduced to generate multiple clustering results, which are then combined together for the following ensemble process. Multiple runs of the multiob-jective clustering method with different randomly selected image features are performed to ensure high quality components as well as necessary diversity for an efficient ensemble. Finally, each datum is assigned to one cluster according to the relationship with the clustering dataset. Experimental results show that interesting segmentation performances on SAR images can be achieved by the proposed technique despite its completely unsupervised nature. Copyright © 2010 ACM.

关键词： Multiobjective optimization

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Solving Nonlinear Equations Systems with a Two-Phase Root-Finder Based on Niching Differential Evolution 15th

Solving Nonlinear Equations Systems with a Two-Phase Root-Fi...

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15th International Conference on Bio-Inspired Computing: Theories and Applications, BIC-TA 2020

作者： Duan, Lianlang Xu, Fei Key Laboratory of Image Processing and Intelligent Control of Education Ministry of China School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan430074 China

ISBN: (纸本)9789811613531

Solving nonlinear equation systems (NESs) is a challenging problems in numerical computation. Two goals should be considered for solving NESs. One is to locate as many roots as possible and the other is to improve the solving precision. In this work, in order to achieve these two goals, a two-phase niching differential evolution (TPNDE) is proposed. The innovation of TPNDE is mainly reflected in the following three aspects. First, a probabilistic mutation mechanism is designed to increase the diversity of the population. Second, a novel reinitialization procedure is proposed to detect converged individuals and explore more new regions that may contain global optima. Third, distribution adjustment local search (DALS) is proposed to deal with the isolated solution and enhance the convergence of the algorithm. To evaluate the performance of TPNDE, we test our TPNDE and 5 state-of-the-art algorithms on 20 NESs with diverse features. The experimental results show that the proposed TPNDE algorithm is better than the other methods. © 2021, Springer Nature Singapore Pte Ltd.

关键词： Nonlinear equations

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A change detection algorithm based on object feature for SAR image

A change detection algorithm based on object feature for SAR...

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2009 Asia-Pacific Conference on Synthetic Aperture Radar, APSAR 2009

作者： Zhang, Xiaohua Li, Hongfeng Jiao, Licheng Institution of Intelligent Information Processing Key Laboratory of Intelligent Perception and Image Understanding of Ministry of Education Xidian University Xi'an 710071 China

ISBN: (纸本)9781424427314

In the detection of change objects of SAR images, regard to the images containing high intensity noise, traditional methods will produce a considerable false alarm. This paper presents a new method of change detection based on directional information. Direction measure is proposed to suppress noises and brighten object contours. Then region blocks which contain changing objects are extracted according to the difference map of direction measure. Finally, changed objects can be obtained using the OTSU threshold method for each region block. The experimental results on SAR images demonstrate the efficiency and accuracy of the proposed method. ©2009 IEEE.

关键词： Synthetic aperture radar

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Improvement and invariance analysis of Zernike moments 1

Improvement and invariance analysis of Zernike moments

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1st International Conference on Communications, Circuits and Systems, ICCCAS 2002

作者： Bin, Ye Xiong, Peng Jia State Key Laboratory for Image Processing and Intelligent Control Institute for Pattern Recognition and Artificial Intelligence Huazhong University of Science and Technology WuhanHubei430074 China

ISBN: (纸本)0780375475

An improved Zernike moment using a region-based shape descriptor is presented. The improved Zernike moment not only has rotation invariance, but also has scale invariance that the unimproved Zernike moment does not have. The experimental results show that the improved Zernike moment has better invariant properties than the unimproved Zernike moment using a region-based shape descriptor. © 2002 IEEE.

关键词： image enhancement

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