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Universal Adversarial Perturbations for CNN Classifiers in EEG-Based BCIs

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arXiv 2019年

作者： Liu, Zihan Meng, Lubin Zhang, Xiao Fang, Weili Wu, Dongrui Key Laboratory of the Ministry of Education for Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan430074 China School of Design and Environment National University of Singapore 117566 Singapore Zhejiang Lab Hangzhou311121 China

Multiple convolutional neural network (CNN) classifiers have been proposed for electroencephalogram (EEG) based brain-computer interfaces (BCIs). However, CNN models have been found vulnerable to universal adversarial perturbations (UAPs), which are small and example-independent, yet powerful enough to degrade the performance of a CNN model, when added to a benign example. This paper proposes a novel total loss minimization (TLM) approach to generate UAPs for EEG-based BCIs. Experimental results demonstrated the effectiveness of TLM on three popular CNN classifiers for both target and non-target attacks. We also verified the transferability of UAPs in EEG-based BCI systems. To our knowledge, this is the first study on UAPs of CNN classifiers in EEG-based BCIs. UAPs are easy to construct, and can attack BCIs in real-time, exposing a potentially critical security concern of BCIs. Copyright © 2019, The Authors. All rights reserved.

关键词： Electroencephalography

Recommendations on Designing Practical Interval Type-2 Fuzzy Systems

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arXiv 2019年

作者： Wu, Dongrui Mendel, Jerry M. Key Laboratory of the Ministry of Education for Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan430074 China Ming Hsieh Department of Electrical Engineering University of Southern California Los AngelesCA United States College of Artificial Intelligence Tianjin Normal University Tianjin China

Interval type-2 (IT2) fuzzy systems have become increasingly popular in the last 20 years. They have demonstrated superior performance in many applications. However, the operation of an IT2 fuzzy system is more complex than that of its type-1 counterpart. There are many questions to be answered in designing an IT2 fuzzy system: Should singleton or non-singleton fuzzifier be used? How many membership functions (MFs) should be used for each input? Should Gaussian or piecewise linear MFs be used? Should Mamdani or Takagi-Sugeno-Kang (TSK) inference be used? Should minimum or product t-norm be used? Should type-reduction be used or not? How to optimize the IT2 fuzzy system? These questions may look overwhelming and confusing to IT2 beginners. In this paper we recommend some representative starting choices for an IT2 fuzzy system design, which hopefully will make IT2 fuzzy systems more accessible to IT2 fuzzy system designers. Copyright © 2019, The Authors. All rights reserved.

关键词： Membership functions

Tiny noise, big mistakes: Adversarial perturbations induce errors in Brain-Computer Interface spellers

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arXiv 2020年

作者： Zhang, Xiao Wu, Dongrui Ding, Lieyun Luo, Hanbin Lin, Chin-Teng Jung, Tzyy-Ping Chavarriaga, Ricardo Ministry of Education Key Laboratory of Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan430074 China School of Civil Engineering and Mechanics Huazhong University of Science and Technology Wuhan430074 China Centre of Artificial Intelligence Faculty of Engineering and Information Technology University of Technology Sydney Sydney2007 Australia La Jolla CA92093 United States Center for Advanced Neurological Engineering Institute of Engineering in Medicine UCSD La Jolla CA92093 United States ZHAW DataLab Zürich University of Applied Sciences Winterthur8401 Switzerland

An electroencephalogram (EEG) based brain-computer interface (BCI) speller allows a user to input text to a computer by thought. It is particularly useful to severely disabled individuals, e.g., amyotrophic lateral sclerosis patients, who have no other effective means of communication with another person or a computer. Most studies so far focused on making EEG-based BCI spellers faster and more reliable;however, few have considered their security. This study, for the first time, shows that P300 and steady-state visual evoked potential BCI spellers are very vulnerable, i.e., they can be severely attacked by adversarial perturbations, which are too tiny to be noticed when added to EEG signals, but can mislead the spellers to spell anything the attacker wants. The consequence could range from merely user frustration to severe misdiagnosis in clinical applications. We hope our research can attract more attention to the security of EEG-based BCI spellers, and more broadly, EEG-based BCIs, which has received little attention before. Copyright © 2020, The Authors. All rights reserved.

关键词： Electroencephalography

Enhanced Moth-flame Optimization Based on Cultural Learning and Gaussian Mutation

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Journal of Bionic Engineering 2018年第4期15卷 751-763页

作者： Liwu Xu Yuanzheng Li Kaicheng Li Gooi Hoay Beng Zhiqiang Jiang Chao Wang Nian Liu State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical Engineering and Electronics Huazhong University of Science and Technology Wuhan 430074 China School of Automation Ministry of Education Key Laboratory of lmage Processing and Intelligence Control Huazhong University of Science and Technology Wuhan 430074 China Nanyang Technological University Singapore 639798 Singapore School of Hydropower and lnformation Engineering Huazhong University of Science and Technology Wuhan 430074 China China Institute of Water Resources and Hydropower Research Beijing 100038 China State Key Laboratory of Alternate Electrical Power System with Renewable Energy Sources North China Electric Power University Beij'ing 102206 China

This paper presents an Enhanced Moth-Flame Optimization （EMFO） technique based on Cultural Learning （CL） and Gaussian Mutation （GM）. The mechanism of CL and the operator of GM are incorporated to the original algorithm of Moth-Flame Optimization （MFO）. CL plays an important role in the inheritance of historical experiences and stimulates moths to obtain information from flames more effectively, which helps MFO enhance its searching ability. Furthermore, in order to overcome the disadvantage of trapping into local optima, the operator of GM is introduced to MFO. This operator acts on the best flame in order to generate several variant ones, which can increase the diversity. The proposed algorithm of EMFO has been comprehensively evaluated on 13 benchmark functions, in comparison with MFO. Simulation results verify that EMFO shows a significant improvement on MFO, in terms of solution quality and algorithmic reliability.

关键词： bioinspired computing moth-flame optimization cultural learning Gaussian mutation benchmark functions

In Vitro Fertilization (IVF) cumulative pregnancy rate prediction from basic patient characteristics

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arXiv 2019年

作者： Zhang, Bo Cui, Yuqi Wang, Meng Li, Jingjing Jin, Lei Wu, Dongrui Reproductive Medicine Center Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei430030 China Key Laboratory of the Ministry of Education for Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan Hubei430074 China

Tens of millions of women suffer from infertility worldwide each year. In vitro fertilization (IVF) is the best choice for many such patients. However, IVF is expensive, time-consuming, and both physically and emotionally demanding. The first question that a patient usually asks before the IVF is how likely she will conceive, given her basic medical examination information. This paper proposes three approaches to predict the cumulative pregnancy rate after multiple oocyte pickup cycles. Experiments on 11,190 patients showed that first clustering the patients into different groups and then building a support vector machine model for each group can achieve the best overall performance. Our model could be a quick and economic approach for reliably estimating the cumulative pregnancy rate for a patient, given only her basic medical examination information, well before starting the actual IVF procedure. The predictions can help the patient make optimal decisions on whether to use her own oocyte or donor oocyte, how many oocyte pickup cycles she may need, whether to use embryo frozen, etc. They will also reduce the patient's cost and time to pregnancy, and improve her quality of life. Copyright © 2019, The Authors. All rights reserved.

关键词： Obstetrics

Identification and Prediction of key Nucleotide Sites Using Machine Learning in Bioinformatics: A Brief Overview

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Identification and Prediction of Key Nucleotide Sites Using ...

IEEE International Conference on Big Data and Cloud Computing (BdCloud)

作者： Jianhua Cai Leyi Wei Kun Zeng Guobao Xiao Fujian Provincial Key Laboratory of Information Processing and Intelligent Control Minjiang University Fuzhou P.R. China College of Mathematics and Computer Science Fuzhou University Fuzhou P.R. China College of Intelligence and Computing Tianjin University Tianjin P.R. China

ISBN: (数字)9781728143286

ISBN: (纸本)9781728143293

Nowadays, the burgeon of machine learning has promoted its wide application in various fields. In Bioinformatics, machine learning computational method has become an indispensable part. Its efficiency and simplicity break the expensive and inefficient barriers of previous experimental methods. This article briefly reviews the application and development of machine learning in identifying and predicting key nucleotide sites (such as 6mA, 5mC, 4mC, etc.) in DNA or RNA. Among them, supervised learning is one of the main methods to this work. Its wide application has provided great convenience for the development of identification and prediction of key nucleotides in Bioinformatics.

关键词： Bioinformatics Feature extraction Machine learning Predictive models Computational modeling DNA Prediction algorithms

Anode Effect prediction based on Expectation Maximization and XGBoost model

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Anode Effect prediction based on Expectation Maximization an...

Data Driven control and Learning Systems (DDCLS)

作者： Zhixin Zhang Gaofeng Xu Hongting Wang Kaibo Zhou School of Automation MOE Key Laboratory of Image Processing and Intelligence Control Huazhong University of Science and Technology Wuhan China

ISBN: (纸本)9781538626191

Anode Effect Prediction problem has been drawing great research interest of scientists, due to its significant values in reducing energy consumption and improving the efficiency of aluminum electrolysis. However, a large number of missing values contained in the collected data from the aluminum reduction cell are always neglected in the works, resulting in a decline in prediction accuracy and generalization ability. To solve this problem, a combined model of Expectation Maximization and XGBoost (EM-XGBoost) is proposed. Firstly, the original incomplete samples collected from the aluminum cells are recovered by Expectation Maximization (EM) algorithm. Afterwards, the XGBoost model trains on the recovered data, and then predicts the result for new samples. The more comprehensive metrics accuracy and F1 Score are introduced for evaluation. The results in the experiment show that the proposed model improves the accuracy to 99.7% and the F1 Score can achieve 99.8% under the premise of forecasting 30 minutes in advance. The proposed model not only has a high prediction accuracy, but also owns an excellent generalization ability.

关键词： Anodes Aluminum Data models Predictive models Electrochemical processes Measurement Filling

A Robust Ensemble Algorithm for Ischemic Stroke Lesion Segmentation: Generalizability and Clinical Utility Beyond the ISLES Challenge

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arXiv 2024年

作者： de la Rosa, Ezequiel Reyes, Mauricio Liew, Sook-Lei Hutton, Alexandre Wiest, Roland Kaesmacher, Johannes Hanning, Uta Hakim, Arsany Zubal, Richard Valenzuela, Waldo Robben, David Sima, Diana M. Anania, Vincenzo Brys, Arne Meakin, James A. Mickan, Anne Broocks, Gabriel Heitkamp, Christian Gao, Shengbo Liang, Kongming Zhang, Ziji Siddiquee, Md Mahfuzur Rahman Myronenko, Andriy Ashtari, Pooya Van Huffel, Sabine Jeong, Hyun-Su Yoon, Chi-Ho Kim, Chulhong Huo, Jiayu Ourselin, Sebastien Sparks, Rachel Clèrigues, Albert Oliver, Arnau Lladó, Xavier Chalcroft, Liam Pappas, Ioannis Bertels, Jeroen Heylen, Ewout Moreau, Juliette Hatami, Nima Frindel, Carole Qayyum, Abdul Mazher, Moona Puig, Domenec Lin, Shao-Chieh Juan, Chun-Jung Hu, Tianxi Boone, Lyndon Goubran, Maged Liu, Yi-Jui Wegener, Susanne Kofler, Florian Ezhov, Ivan Shit, Suprosanna Hernandez Petzsche, Moritz R. Menze, Bjoern Kirschke, Jan S. Wiestler, Benedikt Department of Quantitative Biomedicine University of Zurich Zurich Switzerland Department of Informatics Technical University Munich Germany Icometrix Leuven Belgium ARTORG Center for Biomedical Research University of Bern Bern Switzerland Department of Radiation Oncology University Hospital Bern University of Bern Switzerland University of Bern Bern Switzerland Chan Division of Occupational Science and Occupational Therapy University of Southern California Los AngelesCA United States Stevens Neuroimaging and Informatics Institute Department of Neurology Keck School of Medicine University of Southern California United States University Institute of Diagnostic and Interventional Neuroradiology Inselspital Bern Switzerland University Institute of Diagnostic and Interventional Neuroradiology University Hospital Bern Inselspital University of Bern Bern Switzerland Department of Diagnostic and Interventional neuroradiology University Medical Center Hamburg-Eppendorf Hamburg Germany Department of Medical Imaging Radboud University Medical Center Institute for Health Sciences Nijmegen Netherlands Deepwise AI Lab Beijing China Beijing University of Posts and Telecommunications Bejing China School of Computing and Augmented Intelligence Arizona State University TempeAZ United States NVIDIA Santa ClaraCA United States STADIUS Center for Dynamical Systems Signal Processing and Data Analytics KU Leuven Leuven Belgium Pohang Korea Republic of School of Biomedical Engineering & Imaging Sciences King’s College London United Kingdom Institute of Computer Vision and Robotics University of Girona Spain Wellcome Centre for Human Neuroimaging University College London London United Kingdom Laboratory of Neuro Imaging Stevens Institute for Neuroimaging and Informatics Keck School of Medicine University of Southern California Los Angeles United States KU Leuven Leuven Belgium CREATIS Université Lyon1 CNRS UMR5220 INSERM U1206 INSA-Lyon Villeurbanne696

Diffusion-weighted MRI (DWI) is essential for stroke diagnosis, treatment decisions, and prognosis. However, image and disease variability hinder the development of generalizable AI algorithms with clinical value. We address this gap by presenting a novel ensemble algorithm derived from the 2022 Ischemic Stroke Lesion Segmentation (ISLES) challenge. ISLES’22 provided 400 patient scans with ischemic stroke from various medical centers, facilitating the development of a wide range of cutting-edge segmentation algorithms by the research community. By assessing them against a hidden test set, we identified strengths, weaknesses, and potential biases. Through collaboration with leading teams, we combined top-performing algorithms into an ensemble model that overcomes the limitations of individual solutions. Our ensemble model combines the individual algorithms’ strengths and achieved superior ischemic lesion detection and segmentation accuracy (median Dice score: 0.82, median lesion-wise F1 score: 0.86) on our internal test set compared to individual algorithms. This accuracy generalized well across diverse image and disease variables. Furthermore, the model excelled in extracting clinical biomarkers like lesion types and affected vascular territories. Notably, in a Turing-like test, neuroradiologists consistently preferred the algorithm’s segmentations over manual expert efforts, highlighting increased comprehensiveness and precision. Validation using a real-world external dataset (N=1686) confirmed the model’s generalizability (median Dice score: 0.82, median lesion-wise F1 score: 0.86). The algorithm’s outputs also demonstrated strong correlations with clinical scores (admission NIHSS and 90-day mRS) on par with or exceeding expert-derived results, underlining its clinical relevance. This study offers two key findings. First, we present an ensemble algorithm that detects and segments ischemic stroke lesions on DWI across diverse scenarios on par with expert (neuro)rad

关键词： Diagnosis

Integration of nonlinear disturbance observer within proxy-based sliding mode control for pneumatic muscle actuators

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arXiv 2019年

作者： Cao, Yu Huang, Jian Wu, Dongrui Zhang, Mengshi Xiong, Caihua Li, Zhijun Key Laboratory for Image Processing and Intelligent Control of Education Ministry of China School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan China School of Mechanical Science Engineering State Key Laboratory of Digital Manufacturing Equipment and Technology Huazhong University of Science and Technology Wuhan430074 China College of Automation Science and Engineering South China University of Technology Guangzhou510641 China

This paper presents an integration of nonlinear disturbance observer within proxy-based sliding mode control (IDO-PSMC) approach for Pneumatic Muscle Actuators (PMAs). Due to the nonlinearities, uncertainties, hysteresis, and timevarying characteristics of the PMA, the model parameters are difficult to be identified accurately, which results in unmeasurable uncertainties and disturbances of the system. To solve this problem, a novel design of proxy-based sliding mode controller (PSMC) combined with a nonlinear disturbance observer (DO) is used for the tracking control of the PMA. Our approach combines both the merits of the PSMC and the DO so that it is effective in both reducing the "chattering" phenomeno n and improving the system robustness. A constrained Firefly Algorithm is used to search for the optimal control parameters. Based on the Lyapunov theorem, the states of the PMA are shown to be globally uniformly ultimately bounded. Extensive experiments were conducted to verify the superior performance of our approach, in multiple tracking scenarios. Copyright © 2019, The Authors. All rights reserved.

关键词： Sliding mode control