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Yolk-Shell Nanostructure: An Ideal Architecture to Achieve Harmonious Integration of Magnetic-Plasmonic Hybrid Theranostic Platform

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Advanced materials (Deerfield Beach, Fla.) 2017年第21期29卷 2017 Jun;29(21)页

作者： Li-Sen Lin Xiangyu Yang Zijian Zhou Zhen Yang Orit Jacobson Yijing Liu Angela Yang Gang Niu Jibin Song Huang-Hao Yang Xiaoyuan Chen The Key Lab of Analysis and Detection Technology for Food Safety of the MOE College of Chemistry Fuzhou University Fuzhou 350108 China. Laboratory of Molecular Imaging and Nanomedicine (LOMIN) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institutes of Health (NIH) Bethesda MD 20892 USA.

Magnetic-plasmonic hybrid nanoparticles (MPHNs) have attracted great interest in cancer theranostics. However, the relaxivity of the magnetic component is typically reduced by the plasmonic component in conventional core-shell structured MPHNs, due to the presence of a water-impenetrable coating which severely restricts the proximity of protons to the magnetic portion. To circumvent this issue, yolk-shell structured MPHNs comprising a Fe O core within a hollow cavity encircled by a porous Au outer shell are designed. As expected, the introduction of hollow cavity between the magnetic and plasmonic portions significantly prevents the decline in relaxivity of the Fe O core caused by the Au layer. Moreover, in addition to conferring high near-infrared absorption to plasmonic component, the hollow cavity and the pores in the outer shell can also provide a large storage space and release channels for anticancer drugs. Furthermore, the multicomponent nanoparticles (NPs) still have a compact size of less than 100 nm to ensure efficient tumor accumulation. Taken together, the yolk-shell Fe O @Au NPs can be regarded as an ideal magnetic-plasmonic theranostic platform for magnetic resonance/photoacoustic/positron emission tomography multimodal imaging and light-activated chemothermal synergistic therapy.

关键词： harmonious integration magnetic-plasmonic platforms multimodal imaging synergistic therapy yolk-shell nanostructures

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The development of infrared remote sensors for Chinese meteorological satellites

The development of infrared remote sensors for Chinese meteo...

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International Conference on infrared and Millimeter Waves

作者： Lei Ding Wei Lu Shanghai Institute of Technical Physics Key Laboratory of Infrared System Detection and Imaging Technology Shanghai China

ISBN: (纸本)9781479982738

Meteorological satellites have become an irreplaceable weather and ocean observing tool. Since the first Chinese polar-orbiting meteorological satellite Feng-Yun (FY-1A) was launched successfully in 1988, there are totally 13 meteorological satellites that were launched into both sun synchronous and geostationary orbit. China is among the few countries in the world which are simultaneously operating both orbiting meteorological satellites. All the satellites have been incorporated into the global constellations of operational meteorological satellites within the WMO framework. More satellites are under construction to be the second generation ones. The status of Chinese meteorological satellite mission is introduced in this paper.

关键词： Satellites Satellite broadcasting infrared sensors Remote sensing Radiometry Detectors imaging

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A fully integrated buck converter with a novel digital soft-start circuit

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Australian Journal of Electrical and Electronics Engineering 2016年第2期13卷 91-95页

作者： Zhang, Zhang Song, Mingxin Wang, Xing Cheng, Zhengxi Xie, Guangjun School of Information Science and Technology Fudan University ShanghaiPRC 200433 China School of Electronic Science & Applied Physics Hefei University of Technology Hefei AnhuiPRC 230009 China Key Laboratory of Infrared Imaging Materials and Detectors Shanghai Institute of Technical Physics Chinese Academy of Sciences ShanghaiPRC 200083 China

A novel digital soft-start circuit in the fully integrated buck converter is presented in this paper. The soft-start approach based on a linearly ramped-up reference is proposed to prevent massive in-rush current and overshoot voltage during the start-up phase of the buck converter. Compared with conventional soft-start circuit, the novel circuit is realized by a compact on-chip circuit that requires no external pins and is very simple as well. A fully integrated DC–DC buck converter with proposed circuit has been based on a 0.18 μm mixed signal CMOS process. The results show that this novel soft-start enables the output voltage of the converter to be linearly ramped up to the steady state. © 2015 Engineers Australia.

关键词： Buck converter

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Non-destructive detection of pigments in oil painting by using terahertz tomography

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Science China(Physics,Mechanics & Astronomy) 2015年第12期58卷 193-194页

作者： ZHANG ZhenWei WANG KeJia LEI Yong ZHANG ZhuoYong ZHANG ZhenWei WANG KeJia LEI Yong ZHANG ZhuoYong ZHAO YuanMeng LI ChenYu GU An SHI NingChang ZHAO Kun ZHAN HongLei ZHANG CunLin Beijing Key Laboratory for Terahertz Spectroscopy and Imaging Key Laboratory of Terahertz Optoelectronics Ministry of Education Department of Physics Capital Normal University Beijing 100048 China Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Wuhan 430074 China The Department of Conservation Science and Technology the Palace Museum Beijing 100009 China Beijing Key Laboratory of Optical Detection Technology for Oil and Gas China University of Petroleum Beijing 102249 China Department of Chemistry Capital Normal University Beijing 100048 China

Dear Editors, Terahertz technology has been applied in many fields [1-3]. The protection and restoration of historical relics and cul- tural heritage, which is a new application area of terahertz technology, have been attracting much attention recently [4,5] because of its social significance and market prospects The most important premise is to obtain information of the cultural relics without damaging them again. Therefore the appropriate non-destructively testing methods are urgently needed in this area. Terahertz （THz） wave bridges the gap between microwave and infrared waves.

关键词：层析成像技术无损检测油画颜料太赫兹

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CMOS amplifier for neural signal recording applications

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key Engineering Materials 2015年 645卷 1279-1284页

作者： Zhang, Zhang Cheng, Zhengxi Zhuang, Yiwei Key Laboratory of Infrared Imaging Materials and Detectors Shanghai Institute of Technical Physics Chinese Academy of Sciences Shanghai200083 China State Key Laboratory of ASIC and System Fudan University Shanghai200433 China School of Electronic Science and Applied Physics Hefei University of Technology Hefei Anhui230009 China

A low power low noise CMOS amplifier with integrated filter for neural signal recording is designed and fabricated with CSMC 0.5 μm CMOS process. DC offsets introduced by electrode-tissue interface are rejected through a feedback low-pass filter. The bandwidth of the amplifier is in 3.5Hz-5.5KHz range, and the gain is about 48dB in the midband. AC input differential mode voltage range is 10mV, and DC input differential mode voltage range is 180mV. The amplifier can accommodate 180mV DC offsets drift and 10mV neural spikes. The neural probe array is integrated directly on the surface of the amplifier array chip, and is tested in saline solution, and also is implanted in rats in vivo, the results of the experiments show that the amplifier is suitable for neural signal recording. The power dissipation is about 14μW while consuming 0.16 mm2 of chip area, which satisfies implantable devices requirements. © 2015 Trans Tech Publications, Switzerland.

关键词： Low pass filters

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Polyphenol-Inspired Facile Construction of Smart Assemblies for ATP- and pH-Responsive Tumor MR/Optical imaging and Photothermal Therapy

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Small (Weinheim an der Bergstrasse, Germany) 2017年第20期13卷 2017 May;13(20)页

作者： Xiao-Rong Song Shi-Hua Li Jiayong Dai Liang Song Guoming Huang Ruhui Lin Juan Li Gang Liu Huang-Hao Yang The Key Lab of Analysis and Detection Technology for Food Safety of the MOE State Key Laboratory of Photocatalysis on Energy and Environment College of Chemistry Fuzhou University Fuzhou 350108 China. Academy of Intergrative Medicine Biomedical Research Center Fujian University of Tranditional Chinese Medicine Fuzhou 350122 China. State Key Laboratory of Molecular Vaccinology and Molecular Diagnostic Center for Molecular Imaging and Translational Medicine School of Public Health Xiamen University Xiamen 361005 China.

Smart assemblies have attracted increased interest in various areas, especially in developing novel stimuli-responsive theranostics. Herein, commercially available, natural tannic acid (TA) and iron oxide nanoparticles (Fe O NPs) are utilized as models to construct smart magnetic assemblies based on polyphenol-inspired NPs-phenolic self-assembly between NPs and TA. Interestingly, the magnetic assemblies can be specially disassembled by adenosine triphosphate, which shows a stronger affinity to Fe O NPs than that of TA and partly replaces the surface coordinated TA. The disassembly can further be facilitated by the acidic environment hence causing the remarkable change of the transverse relaxivity and potent "turn-on" of fluorescence (FL) signals. Therefore, the assemblies for specific and sensitive tumor magnetic resonance and FL dual-modal imaging and photothermal therapy after intravenous injection of the assemblies are successfully employed. This work not only provides understandings on the self-assembly between NPs and polyphenols, but also will open new insights for facilely constructing versatile assemblies and extending their biomedical applications.

关键词： fluorescence magnetic properties photothermal therapy self-assembly stimuli-responsive

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A novel method of spike detection for interferograms based on two-step filtering

A novel method of spike detection for interferograms based o...

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4th International Conference on Frontiers of Manufacturing Science and Measuring technology, ICFMM 2014

作者： Zou, Yao Pu Han, Chang Pei Zhang, Lei Pan, Wen Gui Wang, Chao Key Laboratory of Infrared System Detection and Imaging Technology SITP UCAS China

ISBN: (纸本)9783038351924

According to the characteristics of interferogram, we design a new spike detection method, which firstly filters an interferogram with two different ways and then detects spikes based on both results. Theoretical analysis and computer simulation shows that this algorithm performs well in detecting spikes in any position of an interferogram with high accuracy, and can be easily implemented in hardware. © (2014) Trans Tech Publications, Switzerland.

关键词： Computer hardware

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A method to compensate the dead time for three-phase PWM inverters

A method to compensate the dead time for three-phase PWM inv...

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International Conference on Frontiers of Energy, Materials and Information Engineering, ICFMEI 2014

作者： Pan, Wen Gui Zhang, Lei Zou, Yao Pu Wang, Chao Han, Chang Pei Key Laboratory of Infrared System Detection and Imaging Technology SITP UCAS Shanghai China

ISBN: (纸本)9783038352778

As for a vector control of a permanent magnet synchronous motor, this paper analyzed the influence of dead-time effect of three-phase bridge inverters on output voltage and current in details. A novel on-line method was proposed for dead-time effect compensation based on disturbance observer. At last, the method is simulated using MATLAB and the simulation results proves the effectiveness and feasibility of the method presented. © (2014) Trans Tech Publications, Switzerland.

关键词： Pulse width modulation

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Single hazy image restoration based on fields of experts model and guided filtering

Single hazy image restoration based on fields of experts mod...

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IEEE International Conference on Cyber technology in Automation, Control, and Intelligent Systems

作者： Pucheng Zhou Mogen Xue Xiaoli Zhao Imaging Detection Technology Anhui Province Key Laboratory of Polarization Hefei P. R. China

A kind of haze removal algorithm is proposed, so as to improve the visibility of degraded image with only single image. Firstly, the raw atmospheric transmission map is obtained using the dark channel prior. Then, Fields of Experts model with guided filtering is integrated to get the priors from the degraded image, so as to amend the raw atmosphere transmission map. Finally, the scene albedo is restored based on the atmosphere scattering model. Results on a variety of outdoor haze images show the feasibility and validity of our algorithm. Moreover, a comparative study is also proposed with several other state-of-the-art algorithms demonstrate that our algorithm has similar or even better haze removal results.

关键词： Atmospheric modeling Mathematical model Image restoration Filtering Image color analysis Computational modeling

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A design of on-board dual-channel data handling method based on two FPGAs 6

A design of on-board dual-channel data handling method based...

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6th International SpaceWire Conference, SpaceWire 2014

作者： Yaopu, Zou Jiayou, Jiang Changpei, Han Key Laboratory of Infrared System Detection and Imaging Technology Shanghai Institute of Technical Physics UCAS Shanghai China Key Laboratory of Infrared System Detection and Imaging Technology Shanghai Institute of Technical Physics CAS Shanghai China

ISBN: (纸本)9780955719653

SpaceWire is used on FY4 meteorological satellite as on-board data-handling network. Based on SpaceWire, this paper provides a design using two FPGAs and AT7911 chips for the dual-channel data processing of a payload on FY4 to ensure that data can be transported efficiently and reliably. This design has proved to be feasible when tested on the ground. © 2014 University of Dundee.

关键词： Data handling

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