Background: Recently, the popularity of dual-layer flat-panel detector (DL-FPD) based dual-energy cone-beam CT (CBCT) imaging has been increasing. However, the image quality of dual-energy CBCT remains constrained by ...
详细信息
Objective: The aim of this study is to validate the effectiveness of an energy-modulated scatter correction method in suppressing scatter in photon-counting detector (PCD)-based cone beam CT (CBCT) imaging. Approach: ...
详细信息
Skeletal muscle has a robust regeneration ability that is impaired by severe injury,disease,and *** in a decline in skeletal muscle ***,improving skeletal muscle regeneration is a key challenge in treating skeletal mu...
Skeletal muscle has a robust regeneration ability that is impaired by severe injury,disease,and *** in a decline in skeletal muscle ***,improving skeletal muscle regeneration is a key challenge in treating skeletal muscle-related *** to their significant role in tissue regeneration,implantation of M2 macrophages(M2M?) has great potential for improving skeletal muscle ***,we present a short-wave infrared(SWIR) fluorescence imaging technique to obtain more in vivo information for an in-depth evaluation of the skeletal muscle regeneration effect after M2M? *** fluorescence imaging was employed to track implanted M2M? in the injured skeletal muscle of mouse *** is found that the implanted M2M? accumulated at the injury site for two ***,SWIR fluorescence imaging of blood vessels showed that M2M? implantation could improve the relative perfusion ratio on day 5(1.09±0.09 vs 0.85±0.05;p=0.01) and day 9(1.38±0.16 vs 0.95±0.03;p=0.01) post-injury,as well as augment the degree of skeletal muscle regencration on day 13 ***,multiple linear regression analyses determined that post-injury time and relative perfusion ratio could be used as predictive indicators to evaluate skeletal muscle *** results provide more in vivo details about M2M? in skeletal muscle regeneration and confirm that M2M? could promote angiogenesis and improve the degree of skeletal muscle repair,which will guide the research and development of M2M? implantation to improve skeletal muscle regeneration.
暂无评论