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CancerUniT: Towards a Single Unified Model for Effective Detection, Segmentation, and Diagnosis of Eight Major Cancers Using a Large Collection of CT Scans

arXiv

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arXiv 2023年

作者： Chen, Jieneng Xia, Yingda Yao, Jiawen Yan, Ke Zhang, Jianpeng Lu, Le Wang, Fakai Zhou, Bo Qiu, Mingyan Yu, Qihang Yuan, Mingze Fang, Wei Tang, Yuxing Xu, Minfeng Zhou, Jian Zhao, Yuqian Wang, Qifeng Ye, Xianghua Yin, Xiaoli Shi, Yu Chen, Xin Zhou, Jingren Yuille, Alan Liu, Zaiyi Zhang, Ling DAMO Academy Alibaba Group China Johns Hopkins University United States Hupan Lab Hangzhou310023 China Sun Yat-sen University Cancer Center China Sichuan Cancer Hospital China The First Affiliated Hospital of Zhejiang University China Shengjing Hospital of China Medical University China Guangdong Provincial People's Hospital China Guangdong Key Laboratory of Artificial Intelligence in Medical Image Analysis and Application China

Human readers or radiologists routinely perform full-body multi-organ multi-disease detection and diagnosis in clinical practice, while most medical AI systems are built to focus on single organs with a narrow list of a few diseases. This might severely limit AI's clinical adoption. A certain number of AI models need to be assembled non-trivially to match the diagnostic process of a human reading a CT scan. In this paper, we construct a Unified Tumor Transformer (CancerUniT) model to jointly detect tumor existence & location and diagnose tumor characteristics for eight major cancers in CT scans. CancerUniT is a query-based Mask Transformer model with the output of multi-tumor prediction. We decouple the object queries into organ queries, tumor detection queries and tumor diagnosis queries, and further establish hierarchical relationships among the three groups. This clinically-inspired architecture effectively assists inter- and intra-organ representation learning of tumors and facilitates the resolution of these complex, anatomically related multi-organ cancer image reading tasks. CancerUniT is trained end-to-end using a curated large-scale CT images of 10,042 patients including eight major types of cancers and occurring non-cancer tumors (all are pathology-confirmed with 3D tumor masks annotated by radiologists). On the test set of 631 patients, CancerUniT has demonstrated strong performance under a set of clinically relevant evaluation metrics, substantially outperforming both multi-disease methods and an assembly of eight single-organ expert models in tumor detection, segmentation, and diagnosis. This moves one step closer towards a universal high performance cancer screening tool. Copyright © 2023, The Authors. All rights reserved.

关键词： Tumors

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Convergence analysis of Nonconvex Distributed Stochastic Zeroth-order Coordinate Method

Convergence Analysis of Nonconvex Distributed Stochastic Zer...

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IEEE Conference on Decision and Control

作者： Shengjun Zhang Yunlong Dong Dong Xie Lisha Yao Colleen P. Bailey Shengli Fu OS-CAR Laboratory University of North Texas Denton TX USA School of Artificial Intelligence and Automation the MOE Key Laboratory of Image Processing and Intelligent Control and the State Key Laboratory of Digital Manufacturing Equipment and Technology Huazhong University of Science and Technology Wuhan China University of North Texas Denton TX USA

ISBN: (纸本)9781665436601

This paper investigates the stochastic distributed nonconvex optimization problem of minimizing a global cost function formed by the summation of n local cost functions. We solve such a problem by involving zeroth-order (ZO) information exchange. In this paper, we propose a ZO distributed primal–dual coordinate method (ZODIAC) to solve the stochastic optimization problem. Agents approximate their own local stochastic ZO oracle along with coordinates under an adaptive smoothing parameter. We show that the proposed algorithm achieves the convergence rate of ${\mathcal{O}}(\sqrt p /\sqrt T )$ for general nonconvex cost functions. We demonstrate the efficiency of proposed algorithms through a numerical example in comparison with the existing state-of-the-art centralized and distributed ZO algorithms.

关键词： Smoothing methods Conferences Benchmark testing Cost function Approximation algorithms Information exchange Convergence

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Aluminum electrolysis multi-fault diagnosis using wavelet packet decomposition and directed acyclic graph support vector machine 8

Aluminum electrolysis multi-fault diagnosis using wavelet pa...

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8th IEEE Data Driven Control and Learning Systems Conference, DDCLS 2019

作者： Zhou, Kaibo Chen, Xudong Xu, Gaofeng Ge, Yaobao Zhang, Zhixin MOE Key Laboratory of Image Processing and Intelligence Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan430074 China

ISBN: (纸本)9781728114545

The operation condition of aluminum electrolytic cells is critical to the stability of the aluminum electrolysis process. Under the tough working environment, there will be many abnormal states in the cells, detrimental to aluminum quality, aluminum electrolysis efficiency and electrolytic cells life. Therefore, it's of great significance to develop an effective process monitoring and multi-fault diagnosis method. The diagnosis accuracy and the speed of traditional multi-classification methods are limited. To solve these problems, a fault detection and multi-fault diagnosis framework based on wavelet packet decomposition (WPD) and directed acyclic graph support vector machine (DAG-SVM) is proposed. First, features are extracted from aluminum electrolytic cell voltage signals. Then, DAG-SVM is used to detect and diagnose abnormal states. The result shows that the proposed method can detect and diagnose three abnormal states, anode effect state, voltage instability and liquid aluminum fluctuation with a high precision. The accuracy can reach about 86.8%. © 2019 IEEE.

关键词： Failure analysis

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Utility-Oriented Underwater image Quality Assessment Based on Transfer Learning

arXiv

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arXiv 2022年

作者： Chen, Weiling Lin, Rongfu Liao, Honggang Zhao, Tiesong Gu, Ke Le Callet, Patrick Fujian Key Lab for Intelligent Processing and Wireless Transmission of Media Information Fuzhou University Fuzhou350108 China Peng Cheng Laboratory Shenzhen518000 China The Faculty of Information Technology Beijing University of Technology Engineering Research Center of Intelligent Perception and Autonomous Control Ministry of Education Beijing Key Laboratory of Computational Intelligence and Intelligent System Beijing Artificial Intelligence Institute Beijing100124 China Équipe Image Perception et Interaction Laboratoire des Sciences du Numérique de Nantes Université de Nantes France

The widespread image applications have greatly promoted the vision-based tasks, in which the image Quality Assessment (IQA) technique has become an increasingly significant issue. For user enjoyment in multimedia systems, the IQA exploits image fidelity and aesthetics to characterize user experience;while for other tasks such as popular object recognition, there exists a low correlation between utilities and perceptions. In such cases, the fidelity-based and aesthetics-based IQA methods cannot be directly applied. To address this issue, this paper proposes a utility-oriented IQA in object recognition. In particular, we initialize our research in the scenario of underwater fish detection, which is a critical task that has not yet been perfectly addressed. Based on this task, we build an Underwater image Utility Database (UIUD) and a learning-based Underwater image Utility Measure (UIUM). Inspired by the top-down design of fidelity-based IQA, we exploit the deep models of object recognition and transfer their features to our UIUM. Experiments validate that the proposed transfer-learning-based UIUM achieves promising performance in the recognition task. We envision our research provides insights to bridge the researches of IQA and computer vision. Copyright © 2022, The Authors. All rights reserved.

关键词： Multimedia systems

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A New Control System Based on An Improved PID Neural Network Controller for Landslide System Control

A New Control System Based on An Improved PID Neural Network...

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第三十九届中国控制会议

作者： Ying Zhang Shu Sun Cheng Lian Xiaoping Wang the School of Artificial Intelligence and Automation the Key Laboratory of Image Processing and Intelligent Control Huazhong University of Science and Technology the School of Artificial Intelligence and Automation the Key Laboratory of Image Processing and Intelligent Control Huazhong University of Science and Technology the School of Automation Wuhan University of Technology IEEE

In this paper, a new control system based on the improved PID neural network controller（PIDNNC） is designed to control the landslide displacement. In the control system,the fuzzy comprehensive judgement model of landslide system is established to judge whether the system needs to be controlled and give the expected displacement. To solve the problem of random initialization in PIDNNC, This paper proposed an improved PIDNNC based on fuzzy PID controller（F-PIDNNC）.The fuzzy PID controller is used to obtain the proportional,integral and differential coefficients kp, ki and kd. Then the obtained parameters are taken as the initial weights of *** effectiveness of the proposed control system is simulated on Baishuihe and Shiliushubao landslides. The results show that the proposed control system based on F-PIDNNC is much accurate and faster than the traditional one-dimensional fuzzy PID controller and PIDNNC.

关键词： PID neural network Fuzzy PID controller Landslide control Stability evaluation

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Bayesian deep-learning structured illumination microscopy enables reliable super-resolution imaging with uncertainty quantification

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Nature communications 2025年第1期16卷 5027页

作者： Tao Liu Jiahao Liu Dong Li Shan Tan Key Laboratory of Image Processing and Intelligent Control of Ministry of Education of China School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan 430074 China. State Key Laboratory of Membrane Biology Tsinghua-Peking Center for Life Sciences Beijing Frontier Research Center for Biological Structure IDG/McGovern Institute for Brain Research New Cornerstone Science Laboratory School of Life Sciences Tsinghua University Beijing 100084 China. li-dong@***. Key Laboratory of Image Processing and Intelligent Control of Ministry of Education of China School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan 430074 China. shantan@***.

The objective of optical super-resolution imaging is to acquire reliable sub-diffraction information on bioprocesses to facilitate scientific discovery. Structured illumination microscopy (SIM) is acknowledged as the optimal modality for live-cell super-resolution imaging. Although recent deep learning techniques have substantially advanced SIM, their transparency and reliability remain uncertain and under-explored, often resulting in unreliable results and biological misinterpretation. Here, we develop Bayesian deep learning (BayesDL) for SIM, which enhances the reconstruction of densely labeled structures while enabling the quantification of super-resolution uncertainty. With the uncertainty, BayesDL-SIM achieves high-fidelity distribution-informed SIM imaging, allowing for the communication of credibility estimates to users regarding the model outcomes. We also demonstrate that BayesDL-SIM boosts SIM reliability by identifying and preventing erroneous generalizations in various model misuse scenarios. Moreover, the BayesDL uncertainty shows versatile utilities for daily super-resolution imaging, such as error estimation, data acquisition evaluation, etc. Furthermore, we demonstrate the effectiveness and superiority of BayesDL-SIM in live-cell imaging, which reliably reveals F-actin dynamics and the reorganization of the cell cytoskeleton. This work lays the foundation for the reliable implementation of deep learning-based SIM methods in practical applications.

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Advancing Cross-Subject Domain Generalization in Brain–Computer Interfaces With Multiadversarial Strategies

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IEEE Transactions on Instrumentation and Measurement 2025年 74卷

作者： Liu, Yici Qin, Lang Chen, Xin Le Bouquin Jeannes, Regine Louis Coatrieux, Jean Shu, Huazhong Southeast University LIST Key Laboratory of New Generation Artificial Intelligence Technology and Its Interdisciplinary Applications Jiangsu Provincial Joint International Research Laboratory of Medical Information Processing Ministry of Education Nanjing210096 China INSERM RennesF-3502 France The First Affiliated Hospital With Nanjing Medical University Department of Radiology Nanjing210029 China Laboratoire Traitement du Signal et de l’Image Universit de Rennes 1 Rennes35000 France Centre de Recherche en Information Biomedicale Sino-Francais Rennes35042 France National Institute for Health and Medical Research Rennes35000 France

A cross-subject domain generalization (DG) approach with multiadversarial strategies (DGMA) is introduced to reduce brain-computer interfaces (BCIs) systems' dependency on high-quality, subject-specific electroencephalographic (EEG) data, making it adaptable to unseen domains. DGMA leverages annotated training data from other subjects and consists of three modules: 1) prefeature extraction (PFE), enhancing EEG signal separability through preprocessing, data augmentation, and tangent space mapping;2) distribution feature updater (DFU), aligning intersubject feature distributions with marginal maximum mean discrepancy (MMD);and 3) multiadversarial training (MAT), initially using gradient reversal layer (GRL) to amplify domain differences and classification loss, allowing the model to learn diverse domain-specific features before minimizing these differences to balance domain transferability and discriminability. DGMA is capable of better capturing domain-specific features while achieving stronger generalization compared with traditional methods focused solely on minimizing domain differences. Validated on four motor imagery datasets, DGMA achieved state-of-the-art accuracies of 76.1% on BCI Competition IV 2a and 72.4% on the 002-2014 dataset. Additional tests on a private fatigue dataset and the SEED dataset yielded accuracies of 99.5% and 86.6%, respectively. © 1963-2012 IEEE.

关键词： Signal reconstruction

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Domain Generalization for Mammographic image analysis with Contrastive Learning

SSRN

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SSRN 2023年

作者： Li, Zheren Cui, Zhiming Zhang, Lichi Wang, Sheng Lei, Chenjin Ouyang, Xi Chen, Dongdong Zhao, Xiangyu Liu, Chunling Liu, Zaiyi Gu, Yajia Shen, Dinggang Cheng, Jie-Zhi Shanghai United Imaging Intelligence Co. Ltd Shanghai Shanghai200030 China The School of Biomedical Engineering Shanghai Jiao Tong University Shanghai Shanghai200240 China The School of Biomedical Engineering ShanghaiTech University Shanghai Shanghai201210 China The Department of Radiology Guangdong Provincial People’s Hospital Southern Medical University Guangdong Guangzhou510080 China Guangdong Provincial Key Laboratory of Artificial Intelligence in Medical Image Analysis and Application Guangdong Guangzhou510080 China The Department of Radiology Fudan University Shanghai Cancer Center Shanghai Shanghai200032 China

The deep learning technique has been shown to be effectively addressed several image analysis tasks in the computer-aided diagnosis scheme for mammography. The training of an efficacious deep learning model requires large data with diverse styles and qualities. The diversity of data often comes from the use of various scanners of vendors. But, in practice, it is impractical to collect a sufficient amount of diverse data for training. To this end, a novel contrastive learning is developed to equip the deep learning models with better style generalizability. Specifically, the multi-style and multi-view unsupervised self-learning scheme is carried out to seek robust feature embedding against style diversity as a pretrained model. Afterward, the pretrained network is further fine-tuned to the downstream tasks, e.g., mass detection, matching, BI-RADS rating, and breast density classification. The proposed method has been evaluated extensively and rigorously with mammograms from various vendor style domains and several public datasets. The experimental results suggest that the proposed domain generalization method can effectively improve performance of four mammographic image tasks on the data from both seen and unseen domains, and outperform many state-of-the-art (SOTA) generalization methods. © 2023, The Authors. All rights reserved.

关键词： Mammography

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Semi-Supervised and Self-Supervised Collaborative Learning for Prostate 3D MR image Segmentation

Semi-Supervised and Self-Supervised Collaborative Learning f...

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IEEE International Symposium on Biomedical Imaging

作者： Yousuf Babiker M. Osman Cheng Li Weijian Huang Nazik Elsayed Leslie Ying Hairong Zheng Shanshan Wang Paul C. Lauterbur Research Center for Biomedical Imaging Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen China University of Chinese Academy of Sciences Beijing China Faculty of Mathematical and Computer Sciences University of Gezira Wad Madani Sudan Department of Biomedical Engineering and Department of Electrical Engineering University at Buffalo The State University of New York New York USA Guangdong Provincial Key Laboratory of Artificial Intelligence in Medical Image Analysis and Application Guangdong China

Volumetric magnetic resonance (MR) image segmentation plays an important role in many clinical applications. Deep learning (DL) has recently achieved state-of-the-art or even human-level performance on various image segmentation tasks. Nevertheless, manually annotating volumetric MR images for DL model training is labor-exhaustive and time-consuming. In this work, we aim to train a semi-supervised and self-supervised collaborative learning framework for prostate 3D MR image segmentation while using extremely sparse annotations, for which the ground truth annotations are provided for just the central slice of each volumetric MR image. Specifically, semi-supervised learning and self-supervised learning methods are used to generate two independent sets of pseudo labels. These pseudo labels are then fused by the Boolean operation to extract a more confident pseudo label set. The images with either manual or network self-generated labels are then employed to train a segmentation model for target volume extraction. Experimental results on a publicly available prostate MR image dataset demonstrate that, while requiring significantly less annotation effort, our framework generates very encouraging segmentation results. The proposed framework is very useful in clinical applications when training data with dense annotations are difficult to obtain.

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Distributed Online Optimization for Charging and Discharging of Plug-in Electric Vehicles

Distributed Online Optimization for Charging and Discharging...

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IEEE International Conference on Cyborg and Bionic Systems (CBS)

作者： Haiming Xiong Ming Chi Zhi-Wei Liu Dandan Hu Liang-Liang Zhu Cheng Jiang Jun-Ping Gui Yao Rao School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan China Key Laboratory of Image Processing and Intelligent Control Ministry of Education Huazhong University of Science and Technology Wuhan China School of Management South-Central University for Nationalities Wuhan China Nari Group Corporation State Grid Electric Power Research Institute Nanjing China State Grid Electric Power Research Institute Wuhan Efficiency Evaluation Company Limited Wuhan China

The increasing number of uncoordinated charging and discharging for plug-in electric vehicles (PEVs) poses new challenges to the operation of the distribution network. We introduce a dynamic price mechanism so that charging at peak load will lead to an increase in cost. Then, a distributed online charging and discharging scheduling scheme for PEVs based on the dynamic price mechanism is proposed, considering the minimization of charging cost and battery degradation cost. Unlike most of the existing studies that require the future information of PEVs to schedule charging, the proposed algorithm can solve the scheduling problem for PEVs by taking advantage of a distributed alternating direction method of multipliers (ADMM). Simulation results demonstrate the effectiveness and correctness of the proposed scheduling scheme.

关键词： Plug-in electric vehicles Schedules Costs Heuristic algorithms Simulation Dynamic scheduling Minimization

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