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IEEE Computer Society Conference on Computer Vision and Pattern Recognition Workshops (CVPRW)

作者： Xinhan Di Xiaokun Dai Xinkang Zhang Xinrong Chen Deepearthgo Academy for Engineering&Technology Fudan Universiry Shanghai Key Laboratory of Medical Image Computing and Computer Assisted Intervention Fudan University

Currently, mixed reality head-mounted displays tracking the full body of users is an important human-computer interaction mode through the pose of the head and the hands. Unfortunately, users’ virtual representation and experience is limited due to high reconstruction error when simple transformer network architecture is applied. In this paper, we present a novel model, named Dual Attention Poser, which can learn the whole body reconstruction at a high accuracy. The proposed model consists of three key modules. Among them, dual-path attention encoder is designed to extract feature of the sparse signals. Cross attention mixer module enable the fusion of representation in the double path. Attention-gated-mlp decoder is applied to decode the hidden feature from the sparse input through attention gate. Test results on the AMASS dataset show that Dual Attention Poser can reduce the error by up to 18.2% in comparison with the state-of-the-art results.

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Multi-label inductive matrix completion for joint MGMT and IDH1 status prediction for glioma patients 1

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20th International Conference on medical image computing and Computer-Assisted Intervention, MICCAI 2017

作者： Chen, Lei Zhang, Han Thung, Kim-Han Liu, Luyan Lu, Junfeng Wu, Jinsong Wang, Qian Shen, Dinggang Jiangsu Key Laboratory of Big Data Security and Intelligent Processing Nanjing University of Posts and Telecommunications Nanjing China Department of Radiology and BRIC University of North Carolina Chapel Hill United States School of Biomedical Engineering Med-X Research Institute Shanghai Jiao Tong University Shanghai China Department of Neurosurgery Huashan Hospital Fudan University Shanghai China Shanghai Key Lab of Medical Image Computing and Computer Assisted Intervention Shanghai China

ISBN: (数字)9783319661858

ISBN: (纸本)9783319661841

MGMT promoter methylation and IDH1 mutation in high-grade gliomas (HGG) have proven to be the two important molecular indicators associated with better prognosis. Traditionally, the statuses of MGMT and IDH1 are obtained via surgical biopsy, which is laborious, invasive and time-consuming. Accurate presurgical prediction of their statuses based on preoperative imaging data is of great clinical value towards better treatment plan. In this paper, we propose a novel Multi-label Inductive Matrix Completion (MIMC) model, highlighted by the online inductive learning strategy, to jointly predict both MGMT and IDH1 statuses. Our MIMC model not only uses the training subjects with possibly missing MGMT/IDH1 labels, but also leverages the unlabeled testing subjects as a supplement to the limited training dataset. More importantly, we learn inductive labels, instead of directly using transductive labels, as the prediction results for the testing subjects, to alleviate the overfitting issue in small-sample-size studies. Furthermore, we design an optimization algorithm with guaranteed convergence based on the block coordinate descent method to solve the multivariate non-smooth MIMC model. Finally, by using a precious single-center multi-modality presurgical brain imaging and genetic dataset of primary HGG, we demonstrate that our method can produce accurate prediction results, outperforming the previous widely-used single- or multi-task machine learning methods. This study shows the promise of utilizing imaging-derived brain connectome phenotypes for prognosis of HGG in a non-invasive manner. © Springer International Publishing AG 2017.

关键词： Forecasting

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Genome-wide identification of cancer-related polyadenylated and non-polyadenylated RNAs in human breast and lung cell lines

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Science China(Life Sciences) 2013年第5期56卷 503-512,1-4页

作者： ZHAO GuoGuang JIAO Fei LIAO Qi LUO HaiTao LI Hui SUN Liang BU DeChao YU KunTao ZHAO Yi CHEN RunSheng Bioinformatic Research Group Key Laboratory of Intelligent Information ProcessingAdvanced Computing Research LaboratoryInstitute of Computing TechnologyChinese Academy of Sciences University of Chinese Academy of Sciences Department of Biochemistry and Molecular Biology Binzhou Medical College Department of Preventive Medicine School of MedicineNingbo University College of Computer Science and Technology Jilin University Bioinformatics Laboratory and National Laboratory of Biomacromolecules Institute of BiophysicsChinese Academy of SciencesBeijing 100101China

Eukaryotic mRNAs consist of two forms of transcripts:poly(A)+ and poly(A),based on the presence or absence of poly(A) tails at the 3 ***(A)+ mRNAs are mainly protein coding mRNAs,whereas the functions of poly(A) mRNA are largely *** studies have shown that a significant proportion of gene transcripts are poly(A) or bimorphic(containing both poly(A)+ and poly(A) transcripts).We compared the expression levels of poly(A) and poly(A)+ RNA mRNAs in normal and cancer cell *** also investigated the potential functions of these RNA transcripts using an integrative workflow to explore poly(A)+ and poly(A) transcriptome sequences between a normal human mammary gland cell line(HMEC) and a breast cancer cell line(MCF-7),as well as between a normal human lung cell line(NHLF) and a lung cancer cell line(A549).The data showed that normal and cancer cell lines differentially express these two forms of *** ontology(GO) annotation analyses hinted at the functions of these two groups of transcripts and grouped the differentially expressed genes according to the form of their *** data showed that cell cycle-,apoptosis-,and cell death-related functions corresponded to most of the differentially expressed genes in these two forms of transcripts,which were also associated with the ***,translational elongation and translation functions were also found for the poly(A) protein-coding genes in cancer cell *** demonstrate that poly(A) transcripts play an important role in cancer development.

关键词： polyadenylation non-polyadenylation function annotation high throughput sequencing cancer bioinformatics

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Segmentation of pulmonary vessels based on MSFM method

Segmentation of pulmonary vessels based on MSFM method

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International Conference on e-health Networking, Applications and Services (HealthCom)

作者： Xiaowei Wang Liying Cheng Danyang Huang Xuanshuang Gao Daili Liang Liuye He Zhimei Zhang Nan Li Wenjun Tan School of Physical Science and Technology Shenyang Normal University Shenyang China Chinese Academy of Sciences Shenzhen Institutes of Advanced Technology China Key Laboratory of Intelligent Computing in Medical Image Northeastern University Shenyang China

ISBN: (数字)9781728162676

ISBN: (纸本)9781728162683

Accurate segmentation of pulmonary blood vessels from CT images is of great significance for lung disease detection and segmentation of other lung structures. Manual segmentation is difficult to accurately segment vascular tissue for various reasons. Therefore, in view of the existing problems and shortcomings of the existing lung vessel segmentation method, a more efficient lung vessel segmentation algorithm is proposed, that is, the multi-template fast marching method (MSFM algorithm). Firstly, it used the hole filling and maximum inter-class variance algorithm for preprocess. In the process, the lung parenchyma is extracted from the chest CT, and then the lung blood vessels are extracted in the lung parenchymal area using the MSFM algorithm. In the extraction process, the threshold and gradient are used to limit the progress of the process and the lung blood vessels are more accurately segmented. Through experimental verification, the accuracy of lung blood vessel segmentation based on MSFM algorithm is improved.

关键词： image segmentation Computed tomography Pulmonary diseases Lung Surface morphology Blood vessels Biomedical imaging

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ECA-RetinaNet: A Novel Self-Attention RetinaNet for Environmental Microorganism image Object Detection

ECA-RetinaNet: A Novel Self-Attention RetinaNet for Environm...

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IEEE International Conference on Big Data

作者： Hechen Yang Jinzhu Yang Tao Jiang Xin Zhao Jinghua Zhang Peng Zhao Ao Chen Qianqing Nie Marcin Grzegorzek Chen Li Microscopic Image and Medical Image Analysis Group College of Medicine and Biological Information Engineering Northeastern University Shenyang China Key Laboratory of Intelligent Computing in Medical Image Ministry of Education Northeastern University Shenyang Liaoning China School of Intelligent Medicine Chengdu University of Traditional Chinese Medicine Chengdu China International Joint Institute of Robotics and Intelligent Systems Chengdu University of Information Technology Chengdu China Institute of Medical Informatics University of Luebeck Luebeck Germany

The detection of environmental microorganisms is always a difficult task, e specially when the multi-scale environment is complex. For tiny objects in microscopic images, current detection methods face the challenge of accurate identification and localization. In contrast, we propose a convolutional neural network (ECA-RetinaNet) for microscopic object detection of which underlying dataset is a high-quality EMDS-7 dataset. The accuracy of ECA-RetinaNet is high, with a high mean Average Precision (mAP) value of 81.42% in the Environmental Microorganisms (EMS) detection task. Its accuracy has been higher than that of the two-stage object detection network.

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Fast starting point generation method for unobscured two-mirror imaging systems with large field-of-views

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Optik 2023年第1期288卷

作者： Sun, Yiwei Wei, Yangjie Chen, Sike Zhao, Ji Key Laboratory of Intelligent Computing in Medical Image Ministry of Education College of Computer Science and Engineering Northeastern University Wenhua Street 3 Shenyang110819 China College of Mechanical Engineering and Automation Northeastern University Wenhua Street 3 Shenyang110819 China

The surface design methods for unobscured mirror systems have certain limitations, such as time consuming and uncertain optimization possibility. Although neural networks can efficiently improve the design speed and accuracy, the obscuration problem cannot be avoided due to the lack of obscuration judgment in the training process. This study proposes a fast method to generate the starting points for unobscured two-mirror imaging systems with large field-of-views (FOVs) based on neural networks. The design difficulty upper limit is determined to construct the training set of a backpropagation (BP) network, then an obscuration evaluation module is added in the training process. Subsequently, a BP network model of non-obscuration design starting points with a high optimization potential can be quickly generated. Experimental results show that the non-obscuration starting points generated by our method can be easily optimized, and the range of FOV is from 15° × 15 to 20° × 20°. © 2023 Elsevier GmbH

关键词： Imaging systems

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An ensemble framework with l_(21)-norm regularized hypergraph laplacian multi-label learning for clinical data prediction

An ensemble framework with l_(21)-norm regularized hypergrap...

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IEEE International Conference on Bioinformatics and Biomedicine

作者： Peng Cao Jinzhu Yang Shanshan Tang Dazhe Zhao Osmar Zaiane Min Huang Amine Trabelsi College of Computer Science and Engineering Key Laboratory of Intelligent Computing in Medical Image Ministry of Education Northeastern University College of Computer Science and Engineering Northeastern University College of Information Science and Engineering Northeastern University Department of Computing Science University of Alberta Department of Computing Science University of Alberta

ISBN: (纸本)9781728118680

Previous work has shown that machine learning algorithms lend themselves to clinical decision-making and are a valuable tool for physicians. For clinical data, it is often necessary to assign multiple labels to a patient record by choosing from a large number of potential labels. A key problem in learning from multi-labelled data is how to exploit the information contained in the correlations between labels. The hypergraph-based multi-label learning method learns from data by exploiting the spectral property of the hypergraph that encodes the correlation structure of labels. However, the problem with this method is the difficulty with which interpretations can be made. This is mainly due to its inability to recognize the importance of key features in the original feature space. Moreover, it is hard to comprehensively capture the complex structure of the correlations between labels. To overcome these difficulties and improve interpretability, we propose an l_(21)-norm regularized Graph Laplacian multi-label learning to perform feature selection and label embedding simultaneously. In-depth experimental studies, using the publicly available medical Information Mart for Intensive Care (MIMIC-III) database, validate the effectiveness of our approach.

关键词： Multi-label learning High dimensionality Feature selection Ensemble classification MIMIC-III Feature extraction hypergraph patient records Laplacian operator Learning spectral characteristic Machine learning algorithms interpretability Eigenvector

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DFGET: Displacement-Field Assisted Graph Energy Transmitter for Gland Instance Segmentation

arXiv

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arXiv 2023年

作者： Jian, Caiqing Qin, Yongbin Wang, Lihui Engineering Research Center of Text Computing & Cognitive Intelligence Ministry of Education Key Laboratory of Intelligent Medical Image Analysis and Precise Diagnosis of Guizhou Province State Key Laboratory of Public Big Data College of Computer Science and Technology Guizhou University Guiyang550025 China

Gland instance segmentation is an essential but challenging task in the diagnosis and treatment of adenocarcinoma. The existing models usually achieve gland instance segmentation through multi-task learning and boundary loss constraint. However, how to deal with the problems of gland adhesion and inaccurate boundary in segmenting the complex samples remains a challenge. In this work, we propose a displacement-field assisted graph energy transmitter (DFGET) framework to solve these problems. Specifically, a novel message passing manner based on anisotropic diffusion is developed to update the node features, which can distinguish the isomorphic graphs and improve the expressivity of graph nodes for complex samples. Using such graph framework, the gland semantic segmentation map and the displacement field (DF) of the graph nodes are estimated with two graph network branches. With the constraint of DF, a graph cluster module based on diffusion theory is presented to improve the intra-class feature consistency and inter-class feature discrepancy, as well as to separate the adherent glands from the semantic segmentation maps. Extensive comparison and ablation experiments on the GlaS dataset demonstrate the superiority of DFGET and effectiveness of the proposed anisotropic message passing manner and clustering method. Compared to the best comparative model, DFGET increases the object-Dice and object-F1 score by 2.5% and 3.4% respectively, while decreases the object-HD by 32.4%, achieving state-of-the-art performance. © 2023, CC BY-NC-ND.

关键词： Message passing

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Multilevel Perception Boundary-guided Network for Breast Lesion Segmentation in Ultrasound images

arXiv

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arXiv 2023年

作者： Yang, Xing Zhang, Jian Chen, Qijian Wang, Li Wang, Lihui Engineering Research Center of Text Computing & Cognitive Intelligence Ministry of Education Key Laboratory of Intelligent Medical Image Analysis and Precise Diagnosis of Guizhou Province State Key Laboratory of Public Big Data College of Computer Science and Technology Guizhou University Guiyang550025 China

Automatic segmentation of breast tumors from the ultrasound images is essential for the subsequent clinical diagnosis and treatment plan. Although the existing deep learning-based methods have achieved significant progress in automatic segmentation of breast tumor, their performance on tumors with similar intensity to the normal tissues is still not pleasant, especially for the tumor boundaries. To address this issue, we propose a PBNet composed by a multilevel global perception module (MGPM) and a boundary guided module (BGM) to segment breast tumors from ultrasound images. Specifically, in MGPM, the long-range spatial dependence between the voxels in a single level feature maps are modeled, and then the multilevel semantic information is fused to promote the recognition ability of the model for non-enhanced tumors. In BGM, the tumor boundaries are extracted from the high-level semantic maps using the dilation and erosion effects of max pooling, such boundaries are then used to guide the fusion of low and high-level features. Moreover, to improve the segmentation performance for tumor boundaries, a multi-level boundary-enhanced segmentation (BS) loss is proposed. The extensive comparison experiments on both publicly available dataset and in-house dataset demonstrate that the proposed PBNet outperforms the state-of-the-art methods in terms of both qualitative visualization results and quantitative evaluation metrics, with the Dice score, Jaccard coefficient, Specificity and HD95 improved by 0.70%, 1.1%, 0.1% and 2.5% respectively. In addition, the ablation experiments validate that the proposed MGPM is indeed beneficial for distinguishing the non-enhanced tumors and the BGM as well as the BS loss are also helpful for refining the segmentation contours of the tumor. Copyright © 2023, The Authors. All rights reserved.

关键词： Tumors

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Portrait image segmentation based on improved grabcut algorithm 6th

Portrait image segmentation based on improved grabcut algori...

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6th International Conference on Swarm Intelligence, ICSI 2015 held in conjunction with the 2nd BRICS Congress on Computational Intelligence, CCI 2015

作者： Li, Shuai Zheng, Xiaohui Chen, Xianjun Zhan, Yongsong Key Laboratory of Cloud Computing and Complex System Guilin University of Electronic Technology Guilin Guangxi541004 China Guangxi Experiment Center of Information Science Guilin University of Electronic Technology Guilin Guangxi541004 China Key Laboratory of Intelligent Processing of Computer Image and Graphics Guilin University of Electronic Technology Guilin Guangxi541004 China Guangxi Key Laboratory of Trusted Software Guilin University of Electronic Technology Guilin Guangxi541004 China Information Engineering School Haikou College of Economics Haikou Hainan571127

ISBN: (纸本)9783319204680

Traditional computer portrait caricature system mainly take the method that exaggerate and deform real images directly, that lead the facial image background also been deformed when exaggerate facial image. If in pretreatment stage, we segmented the characters and background of the input image, and then do the subsequent processing, the problem may be solved. But for better portrait caricature effects, we need an excellent segmentation algorithm. So, we propose an improved Grabcut image segmentation algorithm and use it to extract the prospect character image for exaggeration and deformation. In practical application, we separate deform and exaggerate the foreground characters image with TPS method, then fuse it with the original or new background picture, get the final image. Application proves, the method solves the background deformation problem well, and improves the quality and rate of image segmentation, caricature synthesis effect reality and natural. © Springer International Publishing Switzerland 2015.

关键词： image segmentation

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