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Frequency-specific Alterations of Large-scale Functional Brain Networks in Patients with Alzheimer＇s Disease

Chinese medical Journal 2015年第5期128卷 602-609页

作者： Yuan-Yuan Qin Ya-Peng Li Shun Zhang Ying Xiong Lin-Ying Guo Shi-Qi Yang Yi-Hao Yao Wei Li Wen-Zhen Zhu Department of Radiology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei 430030 China Department of Control Science and Engineering Image Processing and Intelligent Control Key Laboratory of Education Ministry of China Huazhong University of Science and Technology Wuhan Hubei 430074 China

Background：Previous studies have indicated that the cognitive deficits in patients with Alzheimer＇s disease （AD） may be due to topological deteriorations of the brain ***,whether the selection of a specific frequency band could impact the topological properties is still not *** hypothesis is that the topological properties of AD patients are also ***：Resting state functional magnetic resonance imaging data from l0 right-handed moderate AD patients （mean age：64.3 years; mean mini mental state examination [MMSE]：18.0） and 10 age and gender-matched healthy controls （mean age：63.6 years; mean MMSE：28.2） were enrolled in this *** global efficiency,the clustering coefficient （CC）,the characteristic path length （CpL）,and ＂small-world＂ property were calculated in a wide range of thresholds and averaged within each group,at three different frequency bands （0.01-0.06 Hz,0.06-0.11 Hz,and 0.11-0.25 Hz）.Results：At lower-frequency bands （0.01-0.06 Hz,0.06-0.11 Hz）,the global efficiency,the CC and the ＂small-world＂ properties of AD patients decreased compared to *** at higher-frequency bands （0.11-0.25 Hz）,the CpL was much longer,and the ＂small-world＂ property was disrupted in AD,particularly at a higher *** topological properties changed with different frequency bands,suggesting the existence of disrupted global and local functional organization associated with ***：This study demonstrates that the topological alterations of large-scale functional brain networks inAD patients are frequency dependent,thus providing fundamental support for optimal frequency selection in future related research.

关键词： Alzheimer＇s Disease Frequency Network

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EMD-based Adaptive Wavelet Threshold for Pulse Wave Denoising

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Chinese Journal of Biomedical Engineering(English Edition) 2015年第1期24卷 1-8页

作者： XU Li-shengl SHEN Yan-hua ZHONG Yue KANG Yan Max Q.-H.Meng Sino -Dutch Biomedical and Information Engineering School Northeastern University Key Laboratory of Medical Image Computing (Northeastern University) Ministry of Education Department of Electronic Engineering The Chinese University of Hong Kong

It is inevitable that noises will be introduced during the acquisition of pulse wave signal, which can result in morphology changes of the original pulse wave,and affect the hemodynamic analysis and diagnosis based on pulse wave signals. In order to remove these noises, an adaptive de-noising method based on empirical mode decomposition(EMD) and wavelet threshold is proposed in this paper. Compared with the wavelet threshold method for denoising pulse wave, the proposed approach is more effective, especially at low signal-to-noise ratio.

关键词： pulse wave de-noising EMD adaptive filter wavelet threshold

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medical image protection using hyperchaos-based encryption

Medical image protection using hyperchaos-based encryption

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International Symposium on medical Information & Communication Technology (ISMICT)

作者： Chong Fu Ye Lin Hui-yan Jiang Hong-feng Ma School of Information Science and Engineering Northeastern University Shenyang China Key Laboratory of Medical Image Computing of Ministry of Education Northeastern University Shenyang China TeraRecon Foster City CA United States

ISBN: (纸本)9781479980734

The increasing utilization of telemedicine, especially the teleradiology services, has raised a great deal of concerns in the security of medical images transmitted over open networks. To meet this challenge, a new medical image protection scheme using hyperchaos-based encryption is suggested in this paper. Improvements have been made to both permutation and diffusion methods to address the security problems encountered by many existing chaos-based image ciphers. In the permutation stage, a pixel swapping-based strategy is introduced instead of using the area-preserving chaotic maps, and the swapping operation is determined by the first two state variables of the employed 4-D hyperchaotic system. During the diffusion procedure, the key stream elements, quantified from the other two state variables, are circularly shifted according to the plain-pixels. Consequently, the keystream is related to both the key and the plain-image, which ensures the security against known/ chosen-plaintext attack. Thorough experimental tests are carried out and the results indicate that the proposed scheme provides an effective way for online secure medical image transmission over public networks.

关键词： Biomedical imaging Encryption Chaotic communication Ciphers

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Dynamic restoration schemes in WDM mesh networks with traffic grooming capacity

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Sensors and Transducers 2014年第7期174卷 179-186页

作者： Cao, Chengjian Xuan, Yanjie Du, Li Key Laboratory of Medical Image Computing of Ministry of Education Northeastern University Shenyang China Northeastern University College of Information Science and Engineering P.O. Box 134 Shenyang China

This paper addresses the dynamic recovery problem in the wavelength division multiplexing mesh networks with traffic grooming capacity. We propose two restoration schemes. They are connection dynamic restoration scheme and lightpath dynamic restoration scheme. We also propose two restoration protocols, connection restoration protocol for connection dynamic restoration scheme and lightpath restoration protocol for lightpath dynamic restoration scheme, and formulate a model of restoration switching times for the two restoration schemes. Numerical result shows that connection dynamic restoration scheme and lightpath dynamic restoration scheme can achieve a better tradeoff of resource utilization rate and restoration success rate than protection scheme. Traffic grooming technology helps to improve the restoration success rate as well as to reduce restoration switching time. Connection dynamic restoration scheme yields a better performance than that of lightpath dynamic restoration scheme in terms of restoration success rate and restoration switching time. © 2014 IFSA Publishing, S. L.

关键词： Restoration

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High-speed image compression algorithm based on Gabor transform and fractal theory

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Journal of Information and Computational Science 2014年第5期11卷 1427-1434页

作者： Jiang, Huiyan Shi, Shuo Zhang, Yankong Ma, Zhiyuan Dong, Aoshuang Tong, Qiang Yang, Benqiang Zhang, Libo Software College Northeastern University Shenyang 110004 China Key Laboratory of Medical Image Computing of Ministry of Education Shenyang 110179 China Radiology Department PLA General Hospital Shenyang 110016 China

This paper proposed a novel image compression algorithm based on Gabor transform and fractal theory. First, texture features of image blocks were extracted based on Gabor transform;then cluster process were conducted for the R block and D block based on K-means algorithm, and in the process of block match, only those blocks belong to the same kind were taken into account, which can effectively reduce the encoding time. During the construction of the candidate blocks pool, two simplified approaches were introduced, including the simplification of the eight equidistant transforms and the outliers removed algorithm. Experimental results show that the proposed algorithm can both effectively speed up the encoding and ensure the image perfect visual effect, and has a good robustness. © 2014 by Binary Information Press.

关键词： image compression

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Continuous Outlier Monitoring on Uncertain Data Streams

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Journal of Computer Science & Technology 2014年第3期29卷 436-448页

作者：曹科研王国仁韩东红丁国辉王爱侠石凌旭 College of Information Science and Engineering Northeastern University Key Laboratory of Medical Image Computing Ministry of EducationNortheastern University College of Computer Shenyang Aerospace University Department of Command Information System Engineering Logistic Engineering University of People’s Liberation Army

Outlier detection on data streams is an important task in data mining. The challenges become even larger when considering uncertain data. This paper studies the problem of outlier detection on uncertain data streams. We propose Continuous Uncertain Outlier Detection （CUOD）, which can quickly determine the nature of the uncertain elements by pruning to improve the efficiency. Furthermore, we propose a pruning approach -- Probability Pruning for Continuous Uncertain Outlier Detection （PCUOD） to reduce the detection cost. It is an estimated outlier probability method which can effectively reduce the amount of calculations. The cost of PCUOD incremental algorithm can satisfy the demand of uncertain data streams. Finally, a new method for parameter variable queries to CUOD is proposed, enabling the concurrent execution of different queries. To the best of our knowledge, this paper is the first work to perform outlier detection on uncertain data streams which can handle parameter variable queries simultaneously. Our methods are verified using both real data and synthetic data. The results show that they are able to reduce the required storage and running time.

关键词： outlier detection uncertain data stream data mining parameter variable query

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An image ROI compression algorithm based on hybrid fractal model

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Journal of Information and Computational Science 2014年第4期11卷 1201-1208页

作者： Jiang, Huiyan Zhang, Yankong Shi, Shuo Ma, Zhiyuan Dong, Aoshuang Tong, Qiang Yang, Benqiang Zhang, Libo Software College Northeastern University Shenyang 110004 China Key Laboratory of Medical Image Computing of Ministry of Education Northeast University Shenyang 110179 China Radiology Department PLA General Hospital Shenyang 110014 China

This paper proposed a novel image ROI coding method. First, an abdominal CT image is divided into two parts, the region of interest and the region of no interest;then, the two parts are coded separately based on Huffman and Fractal-SPIHT. In order to verify the validity of the algorithm, this paper compares it with the bifurcation tree algorithm and the Fisher accelerate algorithm. image bit rate and Peak Signal to Noise Ratio (PSNR) are used as evaluation index. The experimental results show that, the proposed image ROI compression algorithm based on hybrid fractal model can guarantee the medical image has better visual effect reduces the data quantity of the image while effectively, the algorithm also has better robustness. 1548-7741/Copyright © 2014 Binary Information Press.

关键词： Fractals

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A novel lung nodules detection scheme based on vessel segmentation on CT images

A novel lung nodules detection scheme based on vessel segmen...

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作者： Jia, Tong Zhang, Hao Meng, Haixiu College of Information Science and Engineering Northeastern University Shenyang110819 China Key Laboratory of Medical Image Computing Ministry of Education Shenyang110819 China

Lung vessels often interfere with the detection of lung nodules. In this paper, a novel computer-Aided lung nodule detection scheme on vessel segmentation is proposed. This paper describes an active contour model which can combine image region mean gray value and image edge energy. It is used to segment and remove lung vessels. A selective shape filter based on Hessian Matrix is used to detect suspicious nodules and remove omitted lung vessels. This paper extracts density, shape and position features of suspicious nodules, and uses a Rule-Based Classification (RBC) method to identify true positive nodules. In the experiment results, the detection sensitivity is about 90% and FP is 1/scan. © 2014 - IOS Press and the authors.

关键词： Computerized tomography

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Modeling and stability analysis of the propagation of a worm

Modeling and stability analysis of the propagation of a worm

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2013 International Conference on Sport Science and Computer Science, CCCS 2013

作者： Yao, Yu Zhang, Zhao Li, Shuo Gao, Fuxiang Yu, Ge College of Information Science and Engineering Northeastern University Shenyang China Key Laboratory of Medical Image Computing Northeastern University Ministry of Education Shenyang China

ISBN: (纸本)9781845649166

Internet worm can spread not only via networks but also through external removable devices. In this paper, considering the influence of removable media, we construct two new worm propagation models. By analyzing the local asymptotic stability at infection-free equilibrium, a basic reproduction number is derived. System is locally stable at infection-free equilibrium if basic reproduction number is less than one;whereas system will lose its stability. Several numerical experiments are given to support the theoretical analysis. Finally, simulating the propagation behavior via simulation experiments, we further demonstrate the correctness of theoretical analysis. © 2014 WIT Press.

关键词： Asymptotic stability

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Modelling and analysis the worm propagation with variable infection rate

Modelling and analysis the worm propagation with variable in...

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2014 International Conference on Communication Technology and Application, CTA 2014

作者： Yao, Y. Wang, Y. Zhang, Y.Y. Gao, F.X. Key Laboratory of Medical Image Computing of Ministry of Education Northeastern University Shenyang 110004 China College of Information Science and Engineering Northeastern University Shenyang 110819 China

ISBN: (纸本)9781845649302

Previous models regarded infection rate as a constant which failed to catch the dynamical process of the infection rates. In this paper, we proposed a SIQRS model with the variable infection rate for the first time. Then we built the corresponding equation of worm propagation and analyzed the existence and stability of worm-free equilibrium. Moreover, in order to verify the effectiveness of the new model, we showed the numerical analysis. The results of numerical analysis show the SIQRS model with the variable infection rate is consistent with the process of the worm propagation more realistically. Finally, we gave some useful strategies which may be applied to constrain the spread of Internet worms. © 2014 WIT Press.

关键词： Numerical analysis

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